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14. Segment Reporting (Tables)
12 Months Ended
Dec. 31, 2020
Segment Reporting [Abstract]  
Information regarding industry segments
Information regarding industry segments at December 31, 2020, 2019, and 2018 and for the years then ended is as follows (in millions):
Life
Science
Clinical
Diagnostics
Other
Operations
Segment net sales 2020$1,231.8 $1,305.2 $8.6 
 2019885.9 1,412.0 13.8 
2018861.7 1,411.8 15.9 
Allocated interest expense2020$8.0 $13.8 $0.1 
20197.4 15.9 0.1 
20187.2 16.7 0.1 
Depreciation and amortization2020$32.8 $65.1 $1.0 
201929.4 71.7 0.9 
201834.1 72.0 0.5 
Segment profit (loss)2020$256.3 $149.1 $(0.6)
 201972.1 148.5 (1.5)
201828.7 (145.7)0.2 
Segment assets2020$607.3 $1,065.6 $9.5 
2019496.1 1,075.8 9.2 
Capital expenditures2020$16.8 $43.6 $3.1 
201916.6 58.9 0.6 
Reconciliation of segment profit to consolidated income before taxes The following reconciles total segment profit to consolidated income before taxes (in millions):
Year Ended December 31,
 202020192018
Total segment profit (loss)$404.8 $219.1 $(116.8)
Foreign currency exchange losses, net(1.8)(2.2)(2.9)
Net corporate operating and other expense not allocated to segments(15.7)(12.9)(10.4)
Change in fair market value of equity securities4,495.8 2,031.0 606.2 
Other income, net24.5 26.1 36.6 
Consolidated income before income taxes$4,907.6 $2,261.1 $512.7 
Reconciliation of Assets from Segment to Consolidated
The following reconciles total segment assets to consolidated total assets (in millions):
 December 31,
 20202019
Total segment assets$1,682.4 $1,581.1 
Cash and other current assets1,098.2 1,233.5 
Property, plant and equipment, net, and operating lease right-of-use
  assets, excluding segment specific balances52.7 56.0 
Goodwill, net291.9 264.1 
Other long-term assets9,847.4 4,863.4 
Total assets$12,972.6 $8,008.9 
Net sales and assets to external customers by geographic area
The following presents net sales to external customers by geographic region based primarily on the location of the use of the product or service (in millions):
 Year Ended December 31,
 202020192018
Europe$857.7 $770.3 $792.0 
Asia546.5 505.0 495.5 
United States1,004.8 899.1 863.6 
Other (primarily Canada and Latin America)136.6 137.3 138.3 
Total net sales$2,545.6 $2,311.7 $2,289.4 

The following presents Property, plant and equipment, net, Operating lease right-of-use assets and Other assets, excluding deferred income taxes, by geographic region based upon the location of the asset (in millions):
 December 31,
 20202019
Europe$208.6 $198.3 
Asia53.3 51.5 
United States454.4 468.7 
Other (primarily Canada and Latin America)12.0 12.7 
Total Property, plant and equipment, net, Operating lease right-of-use assets and Other assets, excluding deferred income taxes$728.3 $731.2