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12. Restructuring Costs (Details) - USD ($)
$ in Thousands
 3 Months Ended
Mar. 31, 2021
Mar. 31, 2020
Dec. 31, 2020
Restructuring Cost and Reserve [Line Items]      
Cost of goods sold $ 326,169 $ 254,276  
European Reorganization      
Restructuring Cost and Reserve [Line Items]      
Restructuring Reserve 71,200   $ 0
Restructuring Charges 75,600    
Payments for Restructuring (2,000)    
Restructuring Reserve, Foreign Currency Translation (Gain) Loss (2,400)    
European Reorganization | Accounts Payable and Accrued Liabilities [Member]      
Restructuring Cost and Reserve [Line Items]      
Restructuring Reserve 35,200    
European Reorganization | Other Noncurrent Liabilities [Member]      
Restructuring Cost and Reserve [Line Items]      
Restructuring Reserve 36,000    
European Reorganization | Selling, General and Administrative Expenses [Member]      
Restructuring Cost and Reserve [Line Items]      
Restructuring Reserve, Accrual Adjustment 34,700    
European Reorganization | Cost of Sales [Member]      
Restructuring Cost and Reserve [Line Items]      
Restructuring Reserve, Accrual Adjustment 23,900    
European Reorganization | Research and Development Expense [Member]      
Restructuring Cost and Reserve [Line Items]      
Restructuring Reserve, Accrual Adjustment 17,000    
European Reorganization | Life Science [Member]      
Restructuring Cost and Reserve [Line Items]      
Restructuring Reserve 12,400   0
Restructuring Charges 12,900    
Payments for Restructuring (100)    
Restructuring Reserve, Foreign Currency Translation (Gain) Loss (400)    
European Reorganization | Clinical Diagnostics [Member]      
Restructuring Cost and Reserve [Line Items]      
Restructuring Reserve 58,800   $ 0
Restructuring Charges 62,700    
Payments for Restructuring (1,900)    
Restructuring Reserve, Foreign Currency Translation (Gain) Loss $ (2,000)