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4. Intangible Assets, Goodwill and Other
9 Months Ended
Sep. 30, 2022
Goodwill and Intangible Assets Disclosure [Abstract]  
Goodwill and Intangible Assets Disclosure GOODWILL AND OTHER PURCHASED INTANGIBLE ASSETS
Changes to goodwill by segment are as follows (in millions):
Life
Science
Clinical
Diagnostics
Total
Balances as of December 31, 2021:
Goodwill$333.3 $349.2 $682.5 
Accumulated impairment losses(41.8)(293.4)(335.2)
Goodwill, net291.5 55.8 347.3 
Acquisitions (see Note 2)— 55.9 55.9 
Currency fluctuations— (3.6)(3.6)
Period increase, net— 52.3 52.3 
Balances as of September 30, 2022:
Goodwill333.3 401.5 734.8 
Accumulated impairment losses(41.8)(293.4)(335.2)
Goodwill, net$291.5 $108.1 $399.6 
Information regarding our identifiable purchased intangible assets with finite and indefinite lives is as follows (in millions):
September 30, 2022
Weighted-Average Remaining Amortization Period (years)Purchase
Price
Accumulated
Amortization
Net
Carrying
Amount
Customer relationships/lists5.13$99.2 $(83.1)$16.1 
Know how3.00158.9 (145.5)13.4 
Developed product technology13.06206.8 (115.6)91.2 
Licenses6.1158.2 (37.0)21.2 
Tradenames6.815.9 (4.2)1.7 
Covenants not to compete3.276.4 (3.7)2.7 
     Total finite-lived intangible assets535.4 (389.1)146.3 
In-process research and development178.8 — 178.8 
     Total purchased intangible assets $714.2 $(389.1)$325.1 

 December 31, 2021
Weighted-Average Remaining Amortization Period (years)Purchase
Price
Accumulated
Amortization
Net
Carrying
Amount
Customer relationships/lists5.27$111.8 $(90.7)$21.1 
Know how3.75171.6 (154.9)16.7 
Developed product technology13.42215.6 (115.6)100.0 
Licenses6.7964.9 (40.6)24.3 
Tradenames7.336.3 (4.4)1.9 
Covenants not to compete3.786.5 (2.9)3.6 
     Total finite-lived intangible assets576.7 (409.1)167.6 
In-process research and development86.3 — 86.3 
     Total purchased intangible assets $663.0 $(409.1)$253.9 


Amortization expense related to purchased intangible assets is as follows (in millions):

Three Months EndedNine Months Ended
 September 30,September 30,
 2022202120222021
Amortization expense$6.2 $7.3 $18.8 $21.7