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14. Segment Reporting (Tables) | 12 Months Ended
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Dec. 31, 2022
Segment Reporting [Abstract] |
Information regarding industry segments | Information regarding industry segments at December 31, 2022, 2021, and 2020 and for the years then ended is as follows (in millions):
|  |  | Life Science |  | Clinical Diagnostics |  | Other Operations
Net sales | 2022 |  | $ | 1,347.2 |  |  | $ | 1,451.0 |  |  | $ | 4.0 |
| 2021 |  | 1,400.8 |  |  | 1,515.9 |  |  | 5.8 |
| 2020 |  | 1,231.8 |  |  | 1,305.2 |  |  | 8.6 |
Depreciation and amortization | 2022 |  | $ | 57.9 |  |  | $ | 79.4 |  |  | $ | — |
| 2021 |  | 54.8 |  |  | 82.8 |  |  | — |
| 2020 |  | 50.5 |  |  | 88.1 |  |  | — |
Operating profit (loss) | 2022 |  | $ | 266.8 |  |  | $ | 217.7 |  |  | $ | (1.9) |
| 2021 |  | 319.7 |  |  | 181.8 |  |  | (1.2) |
| 2020 |  | 282.6 |  |  | 138.3 |  |  | 0.4 |
Segment assets | 2022 |  | $ | 269.9 |  |  | $ | 448.8 |  |  | $ | 0.6 |
| 2021 |  | 207.7 |  |  | 363.5 |  |  | 1.0 |
| 2020 |  | 220.6 |  |  | 401.2 |  |  | 0.5 |
Reconciliation of segment profit to consolidated income before taxes | The following reconciles total operating profit to consolidated income before taxes (in millions):
| Year Ended December 31,
| 2022 |  | 2021 |  | 2020
Total operating profit | $ | 482.6 |  |  | $ | 500.3 |  |  | $ | 421.3 |
Interest expense | (38.1) |  |  | (1.5) |  |  | (21.9) |
Foreign currency exchange gains (losses), net | 0.2 |  |  | (2.7) |  |  | (1.7) |
Gains (losses) from change in fair market value of equity securities and loan receivable | (5,193.6) |  |  | 4,926.2 |  |  | 4,495.8 |
Other income, net | 44.6 |  |  | 26.8 |  |  | 24.5 |
Consolidated income (loss) before income taxes | $ | (4,704.3) |  |  | $ | 5,449.1 |  |  | $ | 4,918.0 |
Reconciliation of Assets from Segment to Consolidated | The following reconciles total segment assets to consolidated total assets (in millions):
|  | December 31,
|  | 2022 |  | 2021
Total segment assets |  | $ | 719.3 |  |  | $ | 572.2 |
Cash, short-term investments and other current assets |  | 2,438.7 |  |  | 1,418.3 |
Property, plant and equipment, net, and operating lease right-of-use assets |  | 679.6 |  |  | 716.4 |
Goodwill, net |  | 406.5 |  |  | 347.3 |
Other long-term assets |  | 9,257.6 |  |  | 14,745.2 |
Total assets |  | $ | 13,501.7 |  |  | $ | 17,799.4 |
Net sales and assets to external customers by geographic area | The following presents net sales to external customers by geographic region based primarily on the location of the use of the product or service (in millions):
|  | Year Ended December 31,
|  | 2022 |  | 2021 |  | 2020
United States |  | 1,155.5 |  |  | $ | 1,130.6 |  |  | $ | 1,004.8 |
Europe |  | $ | 851.9 |  |  | 946.9 |  |  | 857.7 |
Asia |  | 639.4 |  |  | 688.4 |  |  | 546.5 |
Other (primarily Canada and Latin America) |  | 155.4 |  |  | 156.6 |  |  | 136.6 |
Total net sales |  | $ | 2,802.2 |  |  | $ | 2,922.5 |  |  | $ | 2,545.6 |
The following presents Property, plant and equipment, net, Operating lease right-of-use assets and Other assets, excluding deferred income taxes, by geographic region based upon the location of the asset (in millions):
|  | December 31,
|  | 2022 |  | 2021
United States |  | 465.7 |  |  | $ | 478.7 |
Europe |  | $ | 183.7 |  |  | 211.4 |
Asia |  | 63.8 |  |  | 64.9 |
Other (primarily Canada and Latin America) |  | 15.6 |  |  | 16.5 |
Total Property, plant and equipment, net, Operating lease right-of-use assets and Other assets, excluding deferred income taxes |  | $ | 728.8 |  |  | $ | 771.5 |

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- Definition Tabular disclosure of information concerning material long-lived assets (excluding financial instruments, customer relationships with financial institutions, mortgage and other servicing rights, deferred policy acquisition costs, and deferred taxes assets) located in identified geographic areas and/or the amount of revenue from external customers attributed to that country from which revenue is material. An entity may also provide subtotals of geographic information about groups of countries. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 280 -SubTopic 10 -Section 50 -Paragraph 41 -URI https://asc.fasb.org/extlink&oid=126901519&loc=d3e9038-108599 Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 220 -SubTopic 10 -Section S99 -Paragraph 2 -Subparagraph (SX 210.5-03.1) -URI https://asc.fasb.org/extlink&oid=126953954&loc=SL114868664-224227 + Details
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- Definition Tabular disclosure of the profit or loss and total assets for each reportable segment. An entity discloses certain information on each reportable segment if the amounts (a) are included in the measure of segment profit or loss reviewed by the chief operating decision maker or (b) are otherwise regularly provided to the chief operating decision maker, even if not included in that measure of segment profit or loss. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 280 -SubTopic 10 -Section 50 -Paragraph 22 -URI https://asc.fasb.org/extlink&oid=126901519&loc=d3e8736-108599 Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 280 -SubTopic 10 -Section 50 -Paragraph 25 -URI https://asc.fasb.org/extlink&oid=126901519&loc=d3e8813-108599 Reference 3: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 350 -SubTopic 20 -Section 50 -Paragraph 1 -URI https://asc.fasb.org/extlink&oid=121556970&loc=d3e13816-109267 Reference 4: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 280 -SubTopic 10 -Section 50 -Paragraph 30 -URI https://asc.fasb.org/extlink&oid=126901519&loc=d3e8906-108599 + Details
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