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1. Significant Accounting Policies Property, Plant and Equipment (Details) - USD ($) $ in Thousands | 12 Months Ended
--- | ---
Dec. 31, 2022 | Dec. 31, 2021 | Dec. 31, 2020
Property, Plant and Equipment [Line Items] |  |  |
Restricted investments | $ 5,560 | $ 5,560 |
Retained earnings | 9,898,203 | 13,525,343 |
Other assets | 94,599 | 104,189 |
Prepaid Taxes | 7,800 |  |
Income Tax Expense (Benefit) | 1,076,738 | (1,194,798) | $ (1,103,778)
Intangible Assets, Net (Excluding Goodwill) | $ 332,147 | $ 253,939 |
Property, Plant and Equipment | Property, Plant and Equipment Property, plant and equipment are stated at cost, less accumulated depreciation and amortization. Additions and improvements are capitalized, and maintenance and repairs are expensed as incurred. Included in property, plant and equipment are buildings and equipment acquired under capital lease arrangements, reagent rental equipment and capitalized software, including costs for software developed or obtained for internal use. Depreciation is computed on a straight-line basis over the estimated useful lives of the assets. The estimated useful lives of property, plant and equipment are generally as follows: buildings, 10-50 years; leasehold improvements, the life of the improvements or the term of the lease, whichever is shorter; reagent rental equipment, 1-5 years; equipment, 3-12 years; and computer software, 3-5 years. When property and equipment is retired or otherwise disposed of, the cost and accumulated depreciation are relieved from the accounts and the net gain or loss is included in operating expenses. Internal-Use Software Development Costs Costs incurred in the development of internal use software during the application development stage are capitalized and included in Property, plant and equipment, net on the consolidated balance sheets. Such capitalized costs include costs directly associated with the development of the applications. Capitalization of such costs begins when the preliminary project stage is complete and ceases at the point the project is substantially complete and is ready for its intended purpose. Internal-use software is amortized on a straight-line basis over the estimated useful life of between 3-5 years. Costs incurred during the preliminary project stage, as well as maintenance and training costs, are expensed as incurred. |  |
Minimum [Member] | Customer Relationships [Member] |  |  |
Property, Plant and Equipment [Line Items] |  |  |
Finite-Lived Intangible Asset, Useful Life | 4 years |  |
Minimum [Member] | Developed Technology Rights [Member] |  |  |
Property, Plant and Equipment [Line Items] |  |  |
Finite-Lived Intangible Asset, Useful Life | 2 years |  |
Minimum [Member] | License |  |  |
Property, Plant and Equipment [Line Items] |  |  |
Finite-Lived Intangible Asset, Useful Life | 12 years |  |
Minimum [Member] | Trade Names [Member] |  |  |
Property, Plant and Equipment [Line Items] |  |  |
Finite-Lived Intangible Asset, Useful Life | 6 years |  |
Minimum [Member] | Noncompete Agreements [Member] |  |  |
Property, Plant and Equipment [Line Items] |  |  |
Finite-Lived Intangible Asset, Useful Life | 3 years |  |
Minimum [Member] | Building and Building Improvements [Member] |  |  |
Property, Plant and Equipment [Line Items] |  |  |
Property, Plant and Equipment, Useful Life | 10 years |  |
Minimum [Member] | Reagent Rental Equipment [Member] |  |  |
Property, Plant and Equipment [Line Items] |  |  |
Property, Plant and Equipment, Useful Life | 1 year |  |
Minimum [Member] | Equipment [Member] |  |  |
Property, Plant and Equipment [Line Items] |  |  |
Property, Plant and Equipment, Useful Life | 3 years |  |
Minimum [Member] | Software Development |  |  |
Property, Plant and Equipment [Line Items] |  |  |
Property, Plant and Equipment, Useful Life | 3 years |  |
Maximum [Member] | Customer Relationships [Member] |  |  |
Property, Plant and Equipment [Line Items] |  |  |
Finite-Lived Intangible Asset, Useful Life | 16 years |  |
Maximum [Member] | Technology-Based Intangible Assets |  |  |
Property, Plant and Equipment [Line Items] |  |  |
Finite-Lived Intangible Asset, Useful Life | 14 years |  |
Maximum [Member] | Developed Technology Rights [Member] |  |  |
Property, Plant and Equipment [Line Items] |  |  |
Finite-Lived Intangible Asset, Useful Life | 20 years |  |
Maximum [Member] | License |  |  |
Property, Plant and Equipment [Line Items] |  |  |
Finite-Lived Intangible Asset, Useful Life | 13 years |  |
Maximum [Member] | Trade Names [Member] |  |  |
Property, Plant and Equipment [Line Items] |  |  |
Finite-Lived Intangible Asset, Useful Life | 10 years |  |
Maximum [Member] | Noncompete Agreements [Member] |  |  |
Property, Plant and Equipment [Line Items] |  |  |
Finite-Lived Intangible Asset, Useful Life | 10 years |  |
Maximum [Member] | Building and Building Improvements [Member] |  |  |
Property, Plant and Equipment [Line Items] |  |  |
Property, Plant and Equipment, Useful Life | 50 years |  |
Maximum [Member] | Reagent Rental Equipment [Member] |  |  |
Property, Plant and Equipment [Line Items] |  |  |
Property, Plant and Equipment, Useful Life | 5 years |  |
Maximum [Member] | Equipment [Member] |  |  |
Property, Plant and Equipment [Line Items] |  |  |
Property, Plant and Equipment, Useful Life | 12 years |  |
Maximum [Member] | Software Development |  |  |
Property, Plant and Equipment [Line Items] |  |  |
Property, Plant and Equipment, Useful Life | 5 years |  |

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- Definition Disclosure of accounting policy for long-lived, physical asset used in normal conduct of business and not intended for resale. Includes, but is not limited to, work of art, historical treasure, and similar asset classified as collections. + References Reference 1: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 958 -SubTopic 360 -Section 50 -Paragraph 1 -Subparagraph (d) -URI https://asc.fasb.org/extlink&oid=126982197&loc=d3e99779-112916 Reference 2: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 958 -SubTopic 360 -Section 50 -Paragraph 6 -URI https://asc.fasb.org/extlink&oid=126982197&loc=d3e99893-112916 Reference 3: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 360 -SubTopic 10 -Section 50 -Paragraph 1 -URI https://asc.fasb.org/extlink&oid=6391035&loc=d3e2868-110229 + Details
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