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14. Segment Reporting (Tables)

12 Months Ended

Dec. 31, 2022

Segment Reporting [Abstract]

Information regarding industry segments

Information regarding industry segments at December 31, 2022, 2021, and 2020 and for the years then ended is as follows (in millions):

									Life Science						Clinical Diagnostics						Other Operations
Net sales			2022						$	1,347.2					$	1,451.0					$	4.0
			2021						1,400.8						1,515.9						5.8
			2020						1,231.8						1,305.2						8.6
Depreciation and amortization			2022						$	57.9					$	79.4					$	—
			2021						54.8						82.8						—
			2020						50.5						88.1						—
Operating profit (loss)			2022						$	266.8					$	217.7					$	(1.9)
			2021						319.7						181.8						(1.2)
			2020						282.6						138.3						0.4
Segment assets			2022						$	269.9					$	448.8					$	0.6
			2021						207.7						363.5						1.0
			2020						220.6						401.2						0.5

Reconciliation of segment profit to consolidated income before taxes

The following reconciles total operating profit to consolidated income before taxes (in millions):

			Year Ended December 31,
			2022						2021						2020
Total operating profit			$	482.6					$	500.3					$	421.3
Interest expense			(38.1)						(1.5)						(21.9)
Foreign currency exchange gains (losses), net			0.2						(2.7)						(1.7)
Gains (losses) from change in fair market value of equity securities and loan receivable			(5,193.6)						4,926.2						4,495.8
Other income, net			44.6						26.8						24.5
Consolidated income (loss) before income taxes			$	(4,704.3)					$	5,449.1					$	4,918.0

Reconciliation of Assets from Segment to Consolidated

The following reconciles total segment assets to consolidated total assets (in millions):

						December 31,
						2022						2021
Total segment assets						$	719.3					$	572.2
Cash, short-term investments and other current assets						2,438.7						1,418.3
Property, plant and equipment, net, and operating lease right-of-use assets						679.6						716.4
Goodwill, net						406.5						347.3
Other long-term assets						9,257.6						14,745.2
Total assets						$	13,501.7					$	17,799.4

Net sales and assets to external customers by geographic area

The following presents net sales to external customers by geographic region based primarily on the location of the use of the product or service (in millions):

						Year Ended December 31,
						2022						2021						2020
United States						1,155.5						$	1,130.6					$	1,004.8
Europe						$	851.9					946.9						857.7
Asia						639.4						688.4						546.5
Other (primarily Canada and Latin America)						155.4						156.6						136.6
Total net sales						$	2,802.2					$	2,922.5					$	2,545.6

The following presents Property, plant and equipment, net, Operating lease right-of-use assets and Other assets, excluding deferred income taxes, by geographic region based upon the location of the asset (in millions):

						December 31,
						2022						2021
United States						465.7						$	478.7
Europe						$	183.7					211.4
Asia						63.8						64.9
Other (primarily Canada and Latin America)						15.6						16.5
Total Property, plant and equipment, net, Operating lease right-of-use assets and Other assets, excluding deferred income taxes						$	728.8					$	771.5

X

- Definition

Tabular disclosure of all significant reconciling items in the reconciliation of total assets from reportable segments to the entity's consolidated assets.

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Tabular disclosure of the reconciliation of profit (loss) from reportable segments to the consolidated income (loss) before income tax expense (benefit) and discontinued operations. Includes, but is not limited to, reconciliation after income tax if income tax is allocated to the reportable segment.

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Tabular disclosure of the profit or loss and total assets for each reportable segment. An entity discloses certain information on each reportable segment if the amounts (a) are included in the measure of segment profit or loss reviewed by the chief operating decision maker or (b) are otherwise regularly provided to the chief operating decision maker, even if not included in that measure of segment profit or loss.

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