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4. Goodwill and other Purchased Intangible Assets Intangible Assets, Goodwill and Other (Details) - USD ($)
$ in Thousands
 12 Months Ended
Dec. 31, 2022
Dec. 31, 2021
Goodwill [Roll Forward]    
Goodwill period start $ 682,500 $ 627,100
Accumulated impairment loss period start (335,200) (335,200)
Goodwill, net period start 347,343 291,900
Goodwill, Acquired During Period 55,900 55,400
Goodwill, Impairment Loss 0 0
Currency fluctuations 3,300 0
Goodwill, Period Increase (Decrease) 59,200 55,400
Goodwill period end 741,700 682,500
Accumulated impairment loss period end (335,200) (335,200)
Goodwill, net period end 406,488 347,343
Life Science [Member]    
Goodwill [Roll Forward]    
Goodwill period start 333,300 277,900
Accumulated impairment loss period start (41,800) (41,800)
Goodwill, net period start 291,500 236,100
Goodwill, Acquired During Period 0 55,400
Currency fluctuations 0 0
Goodwill, Period Increase (Decrease) 0 55,400
Goodwill period end 333,300 333,300
Accumulated impairment loss period end (41,800) (41,800)
Goodwill, net period end 291,500 291,500
Clinical Diagnostics [Member]    
Goodwill [Roll Forward]    
Goodwill period start 349,200 349,200
Accumulated impairment loss period start (293,400) (293,400)
Goodwill, net period start 55,800 55,800
Goodwill, Acquired During Period 55,900 0
Currency fluctuations 3,300 0
Goodwill, Period Increase (Decrease) 59,200 0
Goodwill period end 408,400 349,200
Accumulated impairment loss period end (293,400) (293,400)
Goodwill, net period end $ 115,000 $ 55,800