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10. Segment Information Segment Profit Reconciliations (Details) - USD ($) $ in Thousands | 3 Months Ended
--- | ---
Mar. 31, 2023 | Mar. 31, 2022
Segment Reporting, Reconciling Item for Operating Profit (Loss) from Segment to Consolidated [Line Items] |  |
Marketable Securities, Unrealized Gain (Loss) | $ (17,525) | $ (4,545,117)
Net sales | 676,844 | 700,062
Operating Income (Loss) | 61,913 | 146,408
Interest expense | 12,337 | 4,048
Foreign Currency Transaction Gain (Loss), before Tax | 2,347 | 2,128
Other Nonoperating Income (Expense) | 50,431 | 32,597
Income (Loss) from Continuing Operations before Income Taxes, Noncontrolling Interest | 84,829 | (4,368,032)
Life Science [Member] |  |
Segment Reporting, Reconciling Item for Operating Profit (Loss) from Segment to Consolidated [Line Items] |  |
Net sales | 323,600 | 347,200
Operating Income (Loss) | 35,700 | 89,600
Other Segments [Member] |  |
Segment Reporting, Reconciling Item for Operating Profit (Loss) from Segment to Consolidated [Line Items] |  |
Net sales | 1,100 | 1,100
Operating Income (Loss) | (100) | (300)
Clinical Diagnostics [Member] |  |
Segment Reporting, Reconciling Item for Operating Profit (Loss) from Segment to Consolidated [Line Items] |  |
Net sales | 352,100 | 351,800
Operating Income (Loss) | 26,300 | 57,100
Operating Segments [Member] |  |
Segment Reporting, Reconciling Item for Operating Profit (Loss) from Segment to Consolidated [Line Items] |  |
Operating Income (Loss) | 61,900 | 146,400
Segment Reconciling Items [Member] |  |
Segment Reporting, Reconciling Item for Operating Profit (Loss) from Segment to Consolidated [Line Items] |  |
Debt and Equity Securities, Unrealized Gain (Loss) | (17,500) | (4,545,100)
Foreign Currency Gain (Loss) [Member] | Segment Reconciling Items [Member] |  |
Segment Reporting, Reconciling Item for Operating Profit (Loss) from Segment to Consolidated [Line Items] |  |
Foreign Currency Transaction Gain (Loss), before Tax | 2,300 | 2,100
Other Nonoperating Income (Expense) [Member] | Segment Reconciling Items [Member] |  |
Segment Reporting, Reconciling Item for Operating Profit (Loss) from Segment to Consolidated [Line Items] |  |
Other Nonoperating Income (Expense) | 50,400 | 32,600
Interest Expense | Segment Reconciling Items [Member] |  |
Segment Reporting, Reconciling Item for Operating Profit (Loss) from Segment to Consolidated [Line Items] |  |
Interest expense | $ (12,300) | $ (4,000)

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