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4. Intangible Assets, Goodwill and Other (Tables)
3 Months Ended
Mar. 31, 2023
Goodwill and Intangible Assets Disclosure [Abstract]  
Changes to goodwill by segment
Changes to goodwill by segment are as follows (in millions):
Life
Science
Clinical
Diagnostics
Total
Balances as of December 31, 2022:
Goodwill$333.3 $408.4 $741.7 
Accumulated impairment losses(41.8)(293.4)(335.2)
Goodwill, net291.5 115.0 406.5 
Acquisitions (see Note 2)— 0.4 0.4 
Foreign currency adjustments— 0.9 0.9 
Period increase, net— 1.3 1.3 
Balances as of March 31, 2023:
Goodwill333.3 409.7 743.0 
Accumulated impairment losses(41.8)(293.4)(335.2)
Goodwill, net$291.5 $116.3 $407.8 
Schedule of identifiable purchased intangible assets with definite lives
Information regarding our identifiable purchased intangible assets with finite and indefinite lives is as follows (in millions):
March 31, 2023
Weighted-Average Remaining Amortization Period (years)Purchase
Price
Accumulated
Amortization
Net
Carrying
Amount
Customer relationships/lists5.0$105.7 $(92.2)$13.5 
Know how2.5167.3 (156.1)11.2 
Developed product technology12.7211.9 (124.6)87.3 
Licenses5.659.0 (39.5)19.5 
Tradenames6.36.1 (4.5)1.6 
Covenants not to compete3.06.4 (4.3)2.1 
     Total finite-lived intangible assets556.4 (421.2)135.2 
In-process research and development192.6 — 192.6 
     Total purchased intangible assets $749.0 $(421.2)$327.8 

 December 31, 2022
Weighted-Average Remaining Amortization Period (years)Purchase
Price
Accumulated
Amortization
Net
Carrying
Amount
Customer relationships/lists5.0$104.7 $(89.9)$14.8 
Know how2.8166.2 (153.9)12.3 
Developed product technology12.8211.1 (121.6)89.5 
Licenses5.859.0 (38.5)20.5 
Tradenames6.66.1 (4.5)1.6 
Covenants not to compete3.16.4 (4.0)2.4 
     Total finite-lived intangible assets553.5 (412.4)141.1 
In-process research and development191.0 — 191.0 
     Total purchased intangible assets $744.5 $(412.4)$332.1 
Finite-lived Intangible Assets Amortization Expense [Table Text Block]
Amortization expense related to purchased intangible assets is as follows (in millions):

Three Months Ended
 March 31,
 20232022
Amortization expense$6.0 $6.3