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10. Segment Information Segment Profit Reconciliations (Details) - USD ($)
$ in Thousands
 3 Months Ended
Mar. 31, 2023
Mar. 31, 2022
Segment Reporting, Reconciling Item for Operating Profit (Loss) from Segment to Consolidated [Line Items]    
Marketable Securities, Unrealized Gain (Loss) $ (17,525) $ (4,545,117)
Net sales 676,844 700,062
Operating Income (Loss) 61,913 146,408
Interest expense 12,337 4,048
Foreign Currency Transaction Gain (Loss), before Tax 2,347 2,128
Other Nonoperating Income (Expense) 50,431 32,597
Income (Loss) from Continuing Operations before Income Taxes, Noncontrolling Interest 84,829 (4,368,032)
Life Science [Member]    
Segment Reporting, Reconciling Item for Operating Profit (Loss) from Segment to Consolidated [Line Items]    
Net sales 323,600 347,200
Operating Income (Loss) 35,700 89,600
Other Segments [Member]    
Segment Reporting, Reconciling Item for Operating Profit (Loss) from Segment to Consolidated [Line Items]    
Net sales 1,100 1,100
Operating Income (Loss) (100) (300)
Clinical Diagnostics [Member]    
Segment Reporting, Reconciling Item for Operating Profit (Loss) from Segment to Consolidated [Line Items]    
Net sales 352,100 351,800
Operating Income (Loss) 26,300 57,100
Operating Segments [Member]    
Segment Reporting, Reconciling Item for Operating Profit (Loss) from Segment to Consolidated [Line Items]    
Operating Income (Loss) 61,900 146,400
Segment Reconciling Items [Member]    
Segment Reporting, Reconciling Item for Operating Profit (Loss) from Segment to Consolidated [Line Items]    
Debt and Equity Securities, Unrealized Gain (Loss) (17,500) (4,545,100)
Foreign Currency Gain (Loss) [Member] | Segment Reconciling Items [Member]    
Segment Reporting, Reconciling Item for Operating Profit (Loss) from Segment to Consolidated [Line Items]    
Foreign Currency Transaction Gain (Loss), before Tax 2,300 2,100
Other Nonoperating Income (Expense) [Member] | Segment Reconciling Items [Member]    
Segment Reporting, Reconciling Item for Operating Profit (Loss) from Segment to Consolidated [Line Items]    
Other Nonoperating Income (Expense) 50,400 32,600
Interest Expense | Segment Reconciling Items [Member]    
Segment Reporting, Reconciling Item for Operating Profit (Loss) from Segment to Consolidated [Line Items]    
Interest expense $ (12,300) $ (4,000)