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Supplemental Cash Flow Information (Tables) | 9 Months Ended
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Sep. 30, 2024
Supplemental Cash Flow Elements [Abstract] |
Schedule of Cash Flow, Supplemental Disclosures | The reconciliation of net loss to net cash provided by operating activities is as follows (in millions):
| Nine Months Ended
| September 30,
| 2024 |  | 2023
Net loss | $ | (1,128.4) |  |  | $ | (987.0) |
Adjustments to reconcile net loss to net cash provided by operating activities: |  |  |
Depreciation and amortization | 112.4 |  |  | 108.7 |
Reduction in the carrying amount of right-of-use assets | 31.1 |  |  | 30.7 |
Share-based compensation | 45.9 |  |  | 45.1 |
Acquired in-process research and development | 29.5 |  |  | — |
Losses from change in fair market value of equity securities and loan receivable | 1,680.3 |  |  | 1,576.5 |
Changes in fair value of contingent consideration | 0.8 |  |  | (18.5) |
Payments for operating lease liabilities | (32.2) |  |  | (30.4) |
Decrease in accounts receivable | 25.6 |  |  | 31.6 |
Increase in inventories | (16.0) |  |  | (61.7) |
(Increase) decrease in other current assets | (4.7) |  |  | 15.0 |
Decrease in accounts payable and other current liabilities | (24.4) |  |  | (72.4) |
Increase in income taxes payable | 21.8 |  |  | 56.4 |
Decrease in deferred income taxes | (408.5) |  |  | (397.4) |
Increase in other long-term liabilities | 1.4 |  |  | 3.9 |
Other | (3.6) |  |  | (6.6) |
Net cash provided by operating activities | $ | 331.0 |  |  | $ | 293.9 |
Non-cash investing activities: |  |  |
Purchased property, plant and equipment | $ | 7.4 |  |  | $ | 2.9 |
Purchased marketable securities and investments | $ | 5.7 |  |  | $ | — |
Sold marketable securities and investments | $ | 0.2 |  |  | $ | — |

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