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Segment Information (Details) - USD ($)
$ in Thousands
 3 Months Ended 9 Months Ended
Sep. 30, 2024
Sep. 30, 2023
Sep. 30, 2024
Sep. 30, 2023
Segment Reporting, Reconciling Item for Operating Profit (Loss) from Segment to Consolidated [Line Items]        
Interest expense $ 12,174 $ 12,398 $ 36,715 $ 37,078
Foreign Currency Transaction Gain (Loss), before Tax (1,641) 1,680 2,012 5,280
Income (Loss) from Continuing Operations before Income Taxes, Noncontrolling Interest 861,620 137,102 (1,433,583) (1,278,496)
Marketable Securities, Unrealized Gain (Loss) 792,888 36,425 (1,680,290) (1,576,542)
Other Nonoperating Income (Expense) 18,081 20,446 70,740 87,365
Net sales 649,729 632,124 1,899,025 1,990,078
Life Science        
Segment Reporting, Reconciling Item for Operating Profit (Loss) from Segment to Consolidated [Line Items]        
Income before income taxes (9,800) 13,000 1,100 76,700
Net sales 260,900 263,500 753,100 887,300
Other Operating Segment        
Segment Reporting, Reconciling Item for Operating Profit (Loss) from Segment to Consolidated [Line Items]        
Income before income taxes 100 (100) (300) (300)
Net sales 0 500 500 2,500
Clinical Diagnostics        
Segment Reporting, Reconciling Item for Operating Profit (Loss) from Segment to Consolidated [Line Items]        
Income before income taxes 74,200 78,000 209,900 166,100
Net sales 388,800 368,100 1,145,400 1,100,300
Operating Segments        
Segment Reporting, Reconciling Item for Operating Profit (Loss) from Segment to Consolidated [Line Items]        
Income before income taxes 64,500 90,900 210,700 242,500
Segment Reporting, Reconciling Item, Excluding Corporate Nonsegment        
Segment Reporting, Reconciling Item for Operating Profit (Loss) from Segment to Consolidated [Line Items]        
Interest expense (12,200) (12,300) (36,700) (37,200)
Foreign Currency Transaction Gain (Loss), before Tax (1,600) 1,700 2,000 5,300
Marketable Securities, Unrealized Gain (Loss) 792,800 36,400 (1,680,300) (1,576,500)
Other Nonoperating Income (Expense) $ 18,100 $ 20,400 $ 70,700 $ 87,400