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Quarterly Financial Data (Unaudited) (Details) - USD ($)
$ / shares in Units, $ in Millions
 3 Months Ended 12 Months Ended
Dec. 31, 2024
Sep. 30, 2024
Jun. 30, 2024
Mar. 31, 2024
Dec. 31, 2023
Sep. 30, 2023
Jun. 30, 2023
Mar. 31, 2023
Dec. 31, 2024
Dec. 31, 2023
Dec. 31, 2022
Quarterly Financial Data [Abstract]                      
Income from operations                 $ 269.0 $ 337.8 $ 482.6
Research and development expense                 295.9 247.4 256.9
Cost of goods sold                 1,187.6 1,244.3 1,234.9
Selling, general and administrative expense                 $ 814.0 $ 841.7 $ 827.8
Net income (loss) per diluted share (in dollars per share) $ (25.57) $ 23.34 $ (76.26) $ 13.45 $ 12.14 $ 3.64 $ (39.59) $ 2.32      
Net income (loss) per basic share (in dollars per share) $ (25.57) $ 23.37 $ (76.26) $ 13.46 $ 12.15 $ 3.65 $ (39.59) $ 2.33 $ (65.36) $ (21.82) $ (121.79)
Net loss $ (715.8) $ 653.2 $ (2,165.5) $ 383.9 $ 349.7 $ 106.3 $ (1,162.3) $ 69.0 $ (1,844.2) $ (637.3) $ (3,627.5)
Gross Profit 342.0 355.9 355.1 325.9 366.3 335.7 362.5 362.4 1,378.9 1,426.9 1,567.3
Net cash used in investing activities                 (160.2) 20.2 (1,207.6)
Net sales $ 667.5 $ 649.7 $ 638.5 $ 610.8 $ 681.2 $ 632.1 $ 681.1 $ 676.8 2,566.5 2,671.2 2,802.2
Net cash provided by operating activities                 $ 455.2 $ 374.9 $ 194.4