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Stock options and warrants (Schedule of Stock-based Compensation) (Details) (USD $)
3 Months Ended
Mar. 31, 2013
Mar. 31, 2012
Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Line Items]    
Share-based compensation, operating expense $ 484,222 $ 221,996
Employees, Officers, and Directors [Member]
   
Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Line Items]    
Share-based compensation, operating expense 483,625 197,402
Investor Relations Activities [Member]
   
Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Line Items]    
Share-based compensation, operating expense    20,227
APPY1 Activities [Member]
   
Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Line Items]    
Share-based compensation, operating expense 597 1,491
Animal Health Activities [Member]
   
Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Line Items]    
Share-based compensation, operating expense    2,876
Selling, general and administrative expenses [Member]
   
Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Line Items]    
Share-based compensation, operating expense 483,625 220,505
Research and development expenses [Member]
   
Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Line Items]    
Share-based compensation, operating expense $ 597 $ 1,491