<SEC-DOCUMENT>0000950103-18-006806.txt : 20180531
<SEC-HEADER>0000950103-18-006806.hdr.sgml : 20180531
<ACCEPTANCE-DATETIME>20180531094941
ACCESSION NUMBER:		0000950103-18-006806
CONFORMED SUBMISSION TYPE:	SD
PUBLIC DOCUMENT COUNT:		1
<RULE>
<RULE-NAME>13p-1
<ITEM>
<ITEM-NUMBER>1.01
<ITEM-PERIOD>20171231
</ITEM>
</RULE>
FILED AS OF DATE:		20180531
DATE AS OF CHANGE:		20180531

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			CHARLES RIVER LABORATORIES INTERNATIONAL INC
		CENTRAL INDEX KEY:			0001100682
		STANDARD INDUSTRIAL CLASSIFICATION:	SERVICES-COMMERCIAL PHYSICAL & BIOLOGICAL RESEARCH [8731]
		IRS NUMBER:				061397316
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		SD
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-15943
		FILM NUMBER:		18870235

	BUSINESS ADDRESS:	
		STREET 1:		251 BALLARDVALE ST
		CITY:			WILMINGTON
		STATE:			MA
		ZIP:			01887
		BUSINESS PHONE:		781-222-6000

	MAIL ADDRESS:	
		STREET 1:		251 BALLARDVALE ST
		CITY:			WILMINGTON
		STATE:			MA
		ZIP:			01887

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	CHARLES RIVER LABORATORIES HOLDINGS INC
		DATE OF NAME CHANGE:	19991208
</SEC-HEADER>
<DOCUMENT>
<TYPE>SD
<SEQUENCE>1
<FILENAME>dp91541_sd.htm
<DESCRIPTION>FORM SD
<TEXT>
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<!-- Field: Rule-Page --><DIV ALIGN="CENTER" STYLE="margin-top: 3pt; margin-bottom: 3pt"><DIV STYLE="font-size: 1pt; border-top: Black 1pt solid; width: 100%">&nbsp;</DIV></DIV><!-- Field: /Rule-Page -->

<P STYLE="margin: 0">&nbsp;</P>

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        <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt; text-indent: 0pt">OMB APPROVAL&nbsp;</P></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="border-right: Black 1pt solid; border-bottom: Black 1pt solid; border-left: Black 1pt solid; padding: 2pt 2pt 2pt 0.15in">
        <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt; text-indent: 0pt">OMB Number: 3235-0697</P>
        <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt; text-indent: 0pt">Expires: June
30, 2019</P>
        <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt; text-indent: 0pt">Estimated average burden</P>
        <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt; text-indent: 0pt">hours per response&hellip;.480.61</P>
        <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt; text-indent: 0pt">&nbsp;</P></TD></TR>
</TABLE><BR STYLE="clear: both">
<P STYLE="font: 16pt Times New Roman, Times, Serif; margin-top: 0pt; text-align: center; margin-bottom: 0pt"><B>UNITED STATES</B></P>

<P STYLE="font: 16pt Times New Roman, Times, Serif; margin-top: 0pt; text-align: center; margin-bottom: 0pt"><B>SECURITIES AND
EXCHANGE COMMISSION</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; text-align: center; margin-bottom: 0pt"><B>Washington, D.C. 20549</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt; text-indent: 0pt">&nbsp;</P>

<P STYLE="font: 16pt Times New Roman, Times, Serif; margin-top: 0pt; text-align: center; margin-bottom: 0pt"></P>

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<P STYLE="font: 16pt Times New Roman, Times, Serif; margin-top: 0pt; text-align: center; margin-bottom: 0pt"><B>FORM SD</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; text-align: center; margin-bottom: 0pt"><B>Specialized Disclosure
Report</B></P>
<!-- Field: Rule-Page --><DIV ALIGN="CENTER" STYLE="margin-top: 10pt; margin-bottom: 10pt"><DIV STYLE="font-size: 1pt; border-top: Black 1pt solid; width: 100%">&nbsp;</DIV></DIV><!-- Field: /Rule-Page -->


<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt">&nbsp;</P>

<P STYLE="font: 16pt Times New Roman, Times, Serif; margin-top: 0pt; text-align: center; margin-bottom: 0pt"><B>Charles River Laboratories International, Inc.</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; text-align: center; margin-bottom: 0pt"><B>(Exact name of registrant as specified in its charter)</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0 0pt 142pt">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="width: 100%; font: 10pt Times New Roman, Times, Serif; border-collapse: collapse">
<TR STYLE="vertical-align: bottom">
    <TD STYLE="width: 43%; text-align: center; padding-left: 0pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><B>State of Delaware</B></FONT></TD>
    <TD STYLE="width: 27%; padding-left: 0pt; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><B>001-15943</B></FONT></TD>
    <TD STYLE="width: 30%; padding-left: 0pt; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><B>06-1397316</B></FONT></TD></TR>
<TR STYLE="vertical-align: bottom">
    <TD STYLE="text-align: center; padding-left: 0pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><B>(State or other jurisdiction</B></FONT></TD>
    <TD STYLE="padding-left: 0pt; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><B>(Commission</B></FONT></TD>
    <TD STYLE="padding-left: 0pt; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><B>(IRS Employer</B></FONT></TD></TR>
<TR STYLE="vertical-align: bottom">
    <TD STYLE="text-align: center; padding-left: 0pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><B>of incorporation or organization)</B></FONT></TD>
    <TD STYLE="padding-left: 0pt; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><B>File Number)</B></FONT></TD>
    <TD STYLE="padding-left: 0pt; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><B>Identification No.)</B></FONT></TD></TR>
<TR STYLE="vertical-align: bottom">
    <TD STYLE="text-align: center; padding-left: 0pt">&nbsp;</TD>
    <TD STYLE="padding-left: 0pt; text-align: center">&nbsp;</TD>
    <TD STYLE="padding-left: 0pt; text-align: center">&nbsp;</TD></TR>
<TR STYLE="vertical-align: bottom">
    <TD COLSPAN="2" STYLE="padding-left: 0pt; text-align: center"><FONT STYLE="font: 10pt Times New Roman, Times, Serif"><B>251 Ballardvale Street</B></FONT></TD>
    <TD STYLE="text-align: center; padding-left: 0pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><B>01887</B></FONT></TD></TR>
<TR STYLE="vertical-align: bottom">
    <TD COLSPAN="2" STYLE="text-align: center; padding-left: 0pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><B>Wilmington, Massachusetts</B></FONT></TD>
    <TD STYLE="padding-left: 0pt; text-align: center">&nbsp;</TD></TR>
<TR STYLE="vertical-align: bottom">
    <TD COLSPAN="2" STYLE="text-align: center; padding-left: 0pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><B>(Address of principal executive offices)</B></FONT></TD>
    <TD STYLE="padding-left: 0pt; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><B>(Zip Code)</B></FONT></TD></TR>
</TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0 0pt 164pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; text-align: center; margin-bottom: 0pt"><B>David P. Johst, telephone: (781) 222-6000</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; text-align: center; margin-bottom: 0pt"><B>(Name and telephone number, including area code,
of the person to contact in connection with this report.)</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0 0pt 70pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"></P>

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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Check the appropriate box to indicate the rule pursuant to which
this form is being filed, and provide the period to which the information in this form applies:</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

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<TD STYLE="width: 0"></TD><TD STYLE="width: 20pt"><FONT STYLE="font-family: Wingdings">x</FONT></TD><TD STYLE="text-align: justify; padding-right: 2pt; padding-left: 2pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Rule
13p-1 under the Securities Exchange Act (17 CFR 240.13p-1) for the reporting period from January 1 to December 31, 2017. </FONT></TD></TR></TABLE>

<P STYLE="margin-top: 0pt; margin-bottom: 0pt; font: 10pt Times New Roman, Times, Serif">&nbsp;</P>


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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"><B>Introduction</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 13pt 0pt 0">Charles River Laboratories International, Inc. (Charles
River) is a full service, early-stage contract research organization. We have built upon our core competency of laboratory animal
medicine and science to develop a diverse portfolio of discovery and safety assessment services, both Good Laboratory Practice
(GLP) and non-GLP, which is able to support our clients from target identification through non-clinical development. We also provide
a suite of products and services to support our client&rsquo;s manufacturing activities. Utilizing our broad portfolio of products
and services enables our clients to create a more flexible drug development model, which reduces their costs, enhances their productivity
and effectiveness, and increases speed to market.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 13pt 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Charles River is aware of the grave concerns and global issues
that stem from the commercialization of <I>Conflict Minerals </I>in the Democratic Republic of the Congo and its adjoining countries.
Thus, Charles River has been actively working with its business partners and others to promote responsible sourcing of <I>Conflict
Minerals</I> within its supply chain.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">In accordance with Rule 13p-1 (17 CFR 240.13p-1) under the Securities
Exchange Act of 1934, as amended, and Form SD (collectively, the Rule), Charles River has conducted a Reasonable Country of Origin
Inquiry (RCOI) and related due diligence consistent with the <I>OECD Due Diligence Guidance for Responsible Supply Chains of Minerals
from Conflict-Affected and High Risk Areas</I>, and the <I>OECD Supplement on Tin, Tantalum, and Tungsten (Second Edition, 2013)
</I>for its Endosafe Products (described below).</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 23pt 0pt 0">For purposes, hereof, all <I>capitalized and italicized</I>
terms used herein and not otherwise defined shall have the meaning ascribed to such terms in the Rule.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 23pt 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"><B>Forward &ndash; Looking Statements</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">This disclosure may contain forward-looking statements within
the meaning of the federal securities laws. Any statements that do not relate to historical or current facts or matters are forward-looking
statements. You can identify some forward-looking statements using forward-looking words, such as &ldquo;intend&rdquo; or the use
of the future tense. Statements concerning current conditions may also be forward-looking if they imply a continuation of current
conditions. Examples of forward-looking statements include, but are not limited to, statements concerning the steps we intend to
take to mitigate the risk that our necessary <I>Conflict Minerals</I> may benefit armed groups.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 5pt 0pt 0">Forward-looking statements are subject to risks and
uncertainties that could cause actual actions or performance to differ materially from those expressed in the forward-looking statements.
These risks and uncertainties include, but are not limited to: (i) the implementation of satisfactory traceability and other compliance
measures by our direct and indirect suppliers, on a timely basis or at all; (ii) whether smelters and refiners and other market
participants responsibly source <I>Conflict Minerals</I>, and (iii) political and regulatory developments, whether in the <I>Covered
Countries</I>, the United States or elsewhere. You are cautioned not to place undue reliance on such forward-looking statements,
which (if any) apply only as of the date of the filing of this disclosure. We do not intend, and undertake no obligation, to publish
revised forward-looking statements to reflect events or circumstances after the date of filing this disclosure or to reflect the
occurrence of unanticipated events.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 5pt 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"><B>Product Overview</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 8pt 0pt 0">Charles River does not procure or otherwise source <I>Conflict
Minerals</I> for any of its products that it manufactures or contracts to manufacture, except with regards to its Endosafe Products.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 8pt 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0.25in 0pt 0">Charles River&rsquo;s Microbial Solutions division
provides clients with <I>in vitro</I> methods for conventional and rapid quality control testing of sterile and non-sterile biopharmaceutical
and consumer products. In connection</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0.25in 0pt 0">&nbsp;</P>


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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">therewith, the Microbial Solutions division contracts to manufacture
for sale to third parties three (3) products (the Endosafe&reg;-PTS&trade; Portable Test System; Endosafe&reg;-nexgen PTS&trade;
Portable Test System; and Endosafe&reg;-MCS&trade; Multi-Cartridge System; collectively the Endosafe Products) that contain electronic
components, some of which include certain <I>Conflict Minerals</I> (tantalum and tin) that are necessary for their functionality
and/or production.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 3pt 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt">The Endosafe Products form a rapid, point-of-use test
system comprised of test cartridges and use of a spectrophotometer where certain assays can be executed (<I>e.g</I>. Gram ID, Inhibition/Enhancement
LAL, Glucan) and can determine if certain injectable therapeutics during the drug manufacturing and production processes are safe
for human use (<I>i.e</I>. whether such therapeutics are endotoxin-free). Tantalum is used in certain capacitors within the power
circuitry, as it dramatically reduces the size of the capacitor and eliminates chemical disposal issues; and tin is used to solder
electronics components on printed circuit boards consistent with industry practice due to its reliable performance.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 5pt 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"><B>SECTION 1 &ndash; CONFLICT MINERALS DISCLOSURE</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt"><TR STYLE="vertical-align: top">
<TD STYLE="width: 0"></TD><TD STYLE="width: 71pt"><B>Item 1.01</B></TD><TD><FONT STYLE="font-size: 10pt"><B>Conflict Minerals Disclosure</B></FONT></TD></TR></TABLE>

<P STYLE="margin-top: 0pt; margin-bottom: 0pt; font: 10pt Times New Roman, Times, Serif">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"><B>Reasonable Country of Origin Inquiry Efforts</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 2pt 0pt 0">Charles River conducted, in good faith, a RCOI in accordance
with the Rule, followed by related due diligence, in regards to its Endosafe Products and the <I>Conflict Minerals</I> utilized
therein, which are necessary for their functionality and/or production. Our supply chain with respect to Endosafe Products is complex,
as we purchase parts and materials directly, or contract with others to manufacture parts, from many suppliers; however, we do
not purchase any <I>Conflict Minerals</I> directly from any smelters, mines or refiners. In most cases, there are multiple layers
of third parties between Charles River and the ultimate upstream source of the <I>Conflict Minerals</I>.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 2pt 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 3pt 0pt 0">We engaged 3E Company (a Verisk Analytics (Nasdaq: VRSK)
business) (3E) to help us obtain information, representations and certifications concerning the presence of <I>Conflict Minerals</I>
in our Endosafe Products, and the sourcing thereof (if any). Specifically, we identified 137 suppliers who provide Endosafe Product
components which have the potential to contain <I>Conflict Minerals</I>. With the help of 3E, we developed and executed a communication
and inquiry program whereby each identified supplier was contacted a minimum of four (4) times <I>via </I>phone-calls and email
communications, and asked to complete an Electronic Industry Citizenship Coalition and Global e-Sustainability Initiative Conflict
Minerals Reporting Template (CMRT). The CMRTs and material correspondence from our suppliers were documented and aggregated into
3E&rsquo;s proprietary <I>3E Supply Chain Platform</I>, which can (among other functions) validate whether smelter and refineries
used by suppliers are recognized as compliant with the Conflict-Free Sourcing Initiative (CFSI) and provide a risk assessment of
our suppliers used. The following outputs were reported:</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 3pt 0pt 0">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt"><TR STYLE="vertical-align: top">
<TD STYLE="width: 0.25in"></TD><TD STYLE="width: 0.25in">&bull;</TD><TD STYLE="padding-right: 6pt">Response Rate: 99%, which represents the percentage of identified suppliers who responded to our
inquiries regarding the presence of <I>Conflict Minerals</I> in our Endosafe Products, and the sourcing thereof.</TD></TR></TABLE>

<P STYLE="margin-top: 0pt; margin-bottom: 0pt; font: 10pt Times New Roman, Times, Serif">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt"><TR STYLE="vertical-align: top">
<TD STYLE="width: 0.25in"></TD><TD STYLE="width: 0.25in">&bull;</TD><TD STYLE="text-align: justify">The responding suppliers account for 98% of the components used in the Endosafe Products.</TD></TR></TABLE>

<P STYLE="margin-top: 0pt; margin-bottom: 0pt; font: 10pt Times New Roman, Times, Serif">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt"><TR STYLE="vertical-align: top">
<TD STYLE="width: 0.25in"></TD><TD STYLE="width: 0.25in">&bull;</TD><TD STYLE="text-align: justify">Of responding suppliers:</TD></TR></TABLE>

<P STYLE="margin-top: 0pt; margin-bottom: 0pt; font: 10pt Times New Roman, Times, Serif">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" STYLE="width: 100%; font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt"><TR STYLE="vertical-align: top">
<TD STYLE="width: 0.75in"></TD><TD STYLE="width: 0.25in; text-align: left">o</TD><TD>26 suppliers reported no <I>Conflict Minerals</I> are
present in their components sold to Charles River;</TD>
</TR></TABLE>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0 0pt 0.75in">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt"><TR STYLE="vertical-align: top">
<TD STYLE="width: 0.75in"></TD><TD STYLE="width: 0.25in">o</TD><TD STYLE="text-align: justify">30 suppliers reported <I>Conflict Minerals</I> are present in their components sold to Charles
River, and such <I>Conflict Minerals</I> are not sourced from any <I>Covered Country</I>;</TD></TR></TABLE>

<P STYLE="margin-top: 0pt; margin-bottom: 0pt; font: 10pt Times New Roman, Times, Serif">&nbsp;</P>


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<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt"><TR STYLE="vertical-align: top">
<TD STYLE="width: 0.75in"></TD><TD STYLE="width: 0.25in">o</TD><TD>17 suppliers reported <I>Conflict Minerals</I> are present in their components sold to Charles River, and such <I>Conflict
Minerals</I> are sourced from a <I>Covered Country</I>, but such suppliers could otherwise represent they are not supporting armed
groups since they buy <I>Conflict Minerals</I> exclusively from smelters and refiners that are CFSI compliant;</TD></TR></TABLE>

<P STYLE="margin-top: 0pt; margin-bottom: 0pt; font: 10pt Times New Roman, Times, Serif">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt"><TR STYLE="vertical-align: top">
<TD STYLE="width: 0.75in"></TD><TD STYLE="width: 0.25in">o</TD><TD>10 suppliers reported <I>Conflict Minerals</I> are present in their components sold to Charles River, and such <I>Conflict
Minerals</I> are sourced from a <I>Covered Country</I>, but sourced from smelters or refiners not compliant with CFSI; and</TD></TR></TABLE>

<P STYLE="margin-top: 0pt; margin-bottom: 0pt; font: 10pt Times New Roman, Times, Serif">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt"><TR STYLE="vertical-align: top">
<TD STYLE="width: 0.75in"></TD><TD STYLE="width: 0.25in">o</TD><TD STYLE="text-align: justify; padding-right: 35pt">45 suppliers could not provide sufficient detail as to whether they sourced
from a <I>Covered Country </I>and/or whether smelters or refiners in their supply chain were CFSI compliant.</TD></TR></TABLE>

<P STYLE="margin-top: 0pt; margin-bottom: 0pt; font: 10pt Times New Roman, Times, Serif">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 2pt 0pt 1in"><I>Note: Suppliers sourcing more than one Conflict
Mineral for components sold to Charles River may have responded differently with regards to each Conflict Mineral sourced, and
therefore any such supplier may have been allocated to more than one output above</I>.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 2pt 0pt 1in">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 5pt 0pt 0">We are encouraged that the above represents improved
engagement with our suppliers versus our previous disclosures (<I>e.g.</I> increase in suppliers representing responsible sourcing
of <I>Conflict Minerals</I> (73, up from 35)). We credit the improvement to the maintenance of our internal and cross-functional
Conflict Minerals Team (with members from Compliance, Legal, Procurement and Operations), which, with the help of 3E, actively
engages with our suppliers and employees to explore solutions in sourcing <I>Conflict Minerals</I> responsibly, and raise awareness
in our supply chain and among our employees of the issues and concerns surrounding <I>Conflict Minerals</I>.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 5pt 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 3pt 0pt 0">We have maintained our Statement on Conflict Minerals
Law Compliance (available at <FONT STYLE="color: blue"><U>http://ir.criver.com/phoenix.zhtml?c=121668&amp;p=irol-Compliance</U></FONT>)
which outlines our commitment to sourcing <I>Conflict Minerals </I>responsibly, and our Compliance &amp; Ethics Hotline (available
at 1-866-294-3699, or <FONT STYLE="color: blue"><U>http://helpline.criver.com</U></FONT>); and we&rsquo;ve provided our suppliers
and employees with access to 3E&rsquo;s Conflict Mineral</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 3pt 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 1pt 0pt 0">Resource Centers where tutorials, further education,
and other resources can be found regarding <I>Conflict Minerals</I> and compliance related laws and regulations.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 1pt 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"><B>Conclusion based on Reasonable Country of Origin Inquiry</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 2pt 0pt 0">Despite our efforts to date, including our RCOI and
related diligence, and in consideration of the complexity of our supply chain and the Endosafe Products themselves, we could not
determine that our supply chain was not sourcing <I>Conflict Minerals</I> from one or more of the <I>Covered Countries</I>. While
we believe a 99% response rate from our suppliers and increase in representations therefrom that <I>Conflict Minerals</I> are sourced
responsibly are significant, we understand further improvements to our evaluation efforts and diligence practices are needed to
achieve 100% engagement with our suppliers and ultimately a supply chain that is <I>DRC Conflict Mineral Free</I>; and therefore,
we will continue to work with our partners, suppliers and supplier candidates to further develop our evaluation efforts and diligence
practices.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 2pt 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"><B>Conflicts Mineral Disclosure</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"><FONT STYLE="font-size: 10pt">This information is publicly available
at <FONT STYLE="color: blue"><U>www.criver.com</U></FONT> at the SEC filings link on the investor relations page</FONT>.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>


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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; text-align: center; margin-bottom: 0pt"><B>SIGNATURES</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt; text-indent: 0pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt; text-indent: 0pt">Pursuant to the requirements of the Securities Exchange Act
of 1934, the registrant has duly caused this report to be signed on its behalf by the duly authorized undersigned.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt; text-indent: 0pt">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="width: 90%; font: 10pt Times New Roman, Times, Serif; border-collapse: collapse; margin-left: 0.5in">
<TR STYLE="vertical-align: top">
    <TD COLSPAN="3"><P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt"><B>CHARLES RIVER LABORATORIES INTERNATIONAL, INC</B>.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt">&nbsp;</P>

</TD></TR>
<TR STYLE="vertical-align: top">
    <TD COLSPAN="2" STYLE="border-bottom: Black 1pt solid">/s/ James C. Foster</TD>
    <TD>&nbsp;</TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="width: 8%"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Name:</FONT></TD>
    <TD STYLE="width: 32%">James C. Foster</TD>
    <TD STYLE="width: 60%">&nbsp;</TD></TR>
<TR STYLE="vertical-align: top">
    <TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Title:</FONT></TD>
    <TD COLSPAN="2"><FONT STYLE="font: 10pt Times New Roman, Times, Serif">Chief Executive Officer and Chairman of the Board</FONT></TD></TR>
<TR STYLE="vertical-align: top">
    <TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Date:</FONT></TD>
    <TD COLSPAN="2"><FONT STYLE="font: 10pt Times New Roman, Times, Serif">May 24, 2018</FONT></TD></TR>
</TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; text-align: center; margin-bottom: 0pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; text-align: center; margin-bottom: 0pt">Form SD</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; text-align: center; margin-bottom: 0pt">(Specialized Disclosure Report)</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; text-align: center; margin-bottom: 0pt">(Reporting period from January 1 to December 31, 2017)</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; text-align: center; margin-bottom: 0pt">&nbsp;</P>


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