<SEC-DOCUMENT>0000905148-25-004067.txt : 20251114
<SEC-HEADER>0000905148-25-004067.hdr.sgml : 20251114
<ACCEPTANCE-DATETIME>20251114165740
ACCESSION NUMBER:		0000905148-25-004067
CONFORMED SUBMISSION TYPE:	SCHEDULE 13G/A
PUBLIC DOCUMENT COUNT:		2
FILED AS OF DATE:		20251114
DATE AS OF CHANGE:		20251114

SUBJECT COMPANY:	

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			CHARLES RIVER LABORATORIES INTERNATIONAL, INC.
		CENTRAL INDEX KEY:			0001100682
		STANDARD INDUSTRIAL CLASSIFICATION:	SERVICES-COMMERCIAL PHYSICAL & BIOLOGICAL RESEARCH [8731]
		ORGANIZATION NAME:           	08 Industrial Applications and Services
		EIN:				061397316
		FISCAL YEAR END:			1227

	FILING VALUES:
		FORM TYPE:		SCHEDULE 13G/A
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	005-59553
		FILM NUMBER:		251487828

	BUSINESS ADDRESS:	
		STREET 1:		251 BALLARDVALE ST
		CITY:			WILMINGTON
		STATE:			MA
		ZIP:			01887
		BUSINESS PHONE:		781-222-6000

	MAIL ADDRESS:	
		STREET 1:		251 BALLARDVALE ST
		CITY:			WILMINGTON
		STATE:			MA
		ZIP:			01887

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	CHARLES RIVER LABORATORIES INTERNATIONAL INC
		DATE OF NAME CHANGE:	20000605

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	CHARLES RIVER LABORATORIES HOLDINGS INC
		DATE OF NAME CHANGE:	19991208

FILED BY:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			NOMURA HOLDINGS INC
		CENTRAL INDEX KEY:			0001163653
		STANDARD INDUSTRIAL CLASSIFICATION:	SECURITY BROKERS, DEALERS & FLOTATION COMPANIES [6211]
		ORGANIZATION NAME:           	02 Finance
		EIN:				000000000
		STATE OF INCORPORATION:			M0
		FISCAL YEAR END:			0331

	FILING VALUES:
		FORM TYPE:		SCHEDULE 13G/A

	BUSINESS ADDRESS:	
		ADDRESS IS A NON US LOCATION: 	YES
		STREET 1:		1-13-1 NIHONBASHI
		STREET 2:		CHUO-KU
		CITY:			TOKYO
		PROVINCE COUNTRY:   	M0
		ZIP:			103-8645
		BUSINESS PHONE:		81-3-5255-1000

	MAIL ADDRESS:	
		ADDRESS IS A NON US LOCATION: 	YES
		STREET 1:		1-13-1 NIHONBASHI
		STREET 2:		CHUO-KU
		CITY:			TOKYO
		PROVINCE COUNTRY:   	M0
		ZIP:			103-8645
</SEC-HEADER>
<DOCUMENT>
<TYPE>SCHEDULE 13G/A
<SEQUENCE>1
<FILENAME>primary_doc.xml
<TEXT>
<XML>
<?xml version="1.0" encoding="UTF-8"?><edgarSubmission xmlns="http://www.sec.gov/edgar/schedule13g" xmlns:com="http://www.sec.gov/edgar/common">
<headerData>
<submissionType>SCHEDULE 13G/A</submissionType>
<filerInfo>
<filer>
<filerCredentials>
<cik>0001163653</cik>
<ccc>XXXXXXXX</ccc>
</filerCredentials>
</filer>
<liveTestFlag>LIVE</liveTestFlag>



</filerInfo>
</headerData>
<formData>
<coverPageHeader>
<amendmentNo>1</amendmentNo>
<securitiesClassTitle>Common Stock, $0.01 par value per share</securitiesClassTitle>
<eventDateRequiresFilingThisStatement>09/30/2025</eventDateRequiresFilingThisStatement>
<issuerInfo>
<issuerCik>0001100682</issuerCik>
<issuerName>CHARLES RIVER LABORATORIES INTERNATIONAL, INC.</issuerName>
<issuerCusip>159864107</issuerCusip>
<issuerPrincipalExecutiveOfficeAddress>
<com:street1>251 Ballardvale Street</com:street1>
<com:city>Wilmington</com:city>
<com:stateOrCountry>MA</com:stateOrCountry>
<com:zipCode>01887</com:zipCode>
</issuerPrincipalExecutiveOfficeAddress>
</issuerInfo>
<designateRulesPursuantThisScheduleFiled>
<designateRulePursuantThisScheduleFiled>Rule 13d-1(b)</designateRulePursuantThisScheduleFiled>
</designateRulesPursuantThisScheduleFiled>
</coverPageHeader>
<coverPageHeaderReportingPersonDetails>

<reportingPersonName>NOMURA HOLDINGS INC</reportingPersonName>
<citizenshipOrOrganization>M0</citizenshipOrOrganization>
<reportingPersonBeneficiallyOwnedNumberOfShares>
<soleVotingPower>807923</soleVotingPower>
<sharedVotingPower>0</sharedVotingPower>
<soleDispositivePower>807923</soleDispositivePower>
<sharedDispositivePower>0</sharedDispositivePower>
</reportingPersonBeneficiallyOwnedNumberOfShares>
<reportingPersonBeneficiallyOwnedAggregateNumberOfShares>807923</reportingPersonBeneficiallyOwnedAggregateNumberOfShares>
<aggregateAmountExcludesCertainSharesFlag>N</aggregateAmountExcludesCertainSharesFlag>
<classPercent>1.6</classPercent>
<typeOfReportingPerson>HC</typeOfReportingPerson>
<comments>(1) Sole voting and dispositive power represents (i) 806,275 shares of Common Stock beneficially owned by Nomura Global Financial Products, Inc. ("NGFP"), (ii) 468 shares of Common Stock beneficially owned by Nomura Securities International, Inc. ("NSI"), and (iii) 1,180 shares of Common Stock beneficially owned by Nomura International PLC ("NIP"). NGFP, NSI and NIP are wholly owned subsidiaries of Nomura Holdings, Inc., which accordingly may be deemed to beneficially own the shares of Common Stock beneficially owned by NGFP, NSI and NIP.&#13;
&#13;
(2) The percent of class is calculated based on 49,215,000 shares of Common Stock outstanding as of September 27, 2025, as reported in the Issuer's quarterly report on Form 10-Q for the fiscal quarter ended September 27, 2025 filed with the SEC on November 5, 2025.</comments>
</coverPageHeaderReportingPersonDetails>
<items>
<item1>
<issuerName>CHARLES RIVER LABORATORIES INTERNATIONAL, INC.</issuerName>
<issuerPrincipalExecutiveOfficeAddress>251 Ballardvale Street, Wilmington, Massachusetts, 01887</issuerPrincipalExecutiveOfficeAddress>
</item1>
<item2>
<filingPersonName>Nomura Holdings, Inc.</filingPersonName>
<principalBusinessOfficeOrResidenceAddress>Nomura Holdings, Inc.: &#13;
13-1, Nihonbashi 1-chome, Chuo-ku, Tokyo 103-8645, Japan</principalBusinessOfficeOrResidenceAddress>
<citizenship>Nomura Holdings, Inc.:&#13;
Japan</citizenship>
</item2>
<item3>
<notApplicableFlag>N</notApplicableFlag>
<typeOfPersonFiling>HC</typeOfPersonFiling>
</item3>
<item4>
<amountBeneficiallyOwned>Items 5-11 of the cover page are incorporated by reference.</amountBeneficiallyOwned>
<classPercent>Items 5-11 of the cover page are incorporated by reference.</classPercent>
<numberOfSharesPersonHas>
<solePowerOrDirectToVote>Items 5-11 of the cover page are incorporated by reference.</solePowerOrDirectToVote>
<sharedPowerOrDirectToVote>Items 5-11 of the cover page are incorporated by reference.</sharedPowerOrDirectToVote>
<solePowerOrDirectToDispose>Items 5-11 of the cover page are incorporated by reference.</solePowerOrDirectToDispose>
<sharedPowerOrDirectToDispose>Items 5-11 of the cover page are incorporated by reference.</sharedPowerOrDirectToDispose>
</numberOfSharesPersonHas>
</item4>
<item5>
<notApplicableFlag>N</notApplicableFlag>
<classOwnership5PercentOrLess>Y</classOwnership5PercentOrLess>
</item5>
<item6>
<notApplicableFlag>Y</notApplicableFlag>
</item6>
<item7>
<notApplicableFlag>N</notApplicableFlag>
<subsidiaryIdentificationAndClassification>See Exhibit A</subsidiaryIdentificationAndClassification>
</item7>
<item8>
<notApplicableFlag>Y</notApplicableFlag>
</item8>
<item9>
<notApplicableFlag>Y</notApplicableFlag>
</item9>
<item10>
<notApplicableFlag>N</notApplicableFlag>
<certifications>By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were acquired and are held in the ordinary course of business and were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under ?? 240.14a-11.</certifications>
</item10>
</items>
<exhibitInfo>Exhibit A - Subsidiaries</exhibitInfo>
<signatureInformation>
<reportingPersonName>NOMURA HOLDINGS INC</reportingPersonName>
<signatureDetails>
<signature>/s/ Samir Patel</signature>
<title>Samir Patel, Managing Director</title>
<date>11/14/2025</date>
</signatureDetails>
</signatureInformation>
</formData>

</edgarSubmission>
</XML>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>EX-99.1
<SEQUENCE>2
<FILENAME>subsidiaries.htm
<TEXT>
<html>
  <head>
    <title></title>
    <!-- Licensed to: Sidley
         Document created using Broadridge PROfile 25.8.1.5328
         Copyright 1995 - 2025 Broadridge -->
  </head>
<body bgcolor="#ffffff" style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; text-align: left; color: #000000;">
  <div>
    <div style="color: rgb(0, 0, 0); font-size: 13.3333px; font-style: normal; font-variant-ligatures: normal; font-variant-caps: normal; letter-spacing: normal; orphans: 2; text-indent: 0px; text-transform: none; widows: 2; word-spacing: 0px; -webkit-text-stroke-width: 0px; white-space: normal; background-color: rgb(255, 255, 255); text-decoration-thickness: initial; text-decoration-style: initial; text-decoration-color: initial; text-align: center; font-weight: bold;">EXHIBIT A</div>
    <div style="color: rgb(0, 0, 0); font-size: 13.3333px; font-style: normal; font-variant-ligatures: normal; font-variant-caps: normal; font-weight: 400; letter-spacing: normal; orphans: 2; text-indent: 0px; text-transform: none; widows: 2; word-spacing: 0px; -webkit-text-stroke-width: 0px; white-space: normal; background-color: rgb(255, 255, 255); text-decoration-thickness: initial; text-decoration-style: initial; text-decoration-color: initial;"><br>
    </div>
    <div style="color: rgb(0, 0, 0); font-size: 13.3333px; font-style: normal; font-variant-ligatures: normal; font-variant-caps: normal; letter-spacing: normal; orphans: 2; text-indent: 0px; text-transform: none; widows: 2; word-spacing: 0px; -webkit-text-stroke-width: 0px; white-space: normal; background-color: rgb(255, 255, 255); text-decoration-thickness: initial; text-decoration-style: initial; text-decoration-color: initial; text-align: center; font-weight: bold;">SUBSIDIARIES</div>
    <div style="color: rgb(0, 0, 0); font-size: 13.3333px; font-style: normal; font-variant-ligatures: normal; font-variant-caps: normal; font-weight: 400; letter-spacing: normal; orphans: 2; text-indent: 0px; text-transform: none; widows: 2; word-spacing: 0px; -webkit-text-stroke-width: 0px; white-space: normal; background-color: rgb(255, 255, 255); text-decoration-thickness: initial; text-decoration-style: initial; text-decoration-color: initial;"><br>
    </div>
    <div style="color: rgb(0, 0, 0); font-size: 13.3333px; font-style: normal; font-variant-ligatures: normal; font-variant-caps: normal; font-weight: 400; letter-spacing: normal; orphans: 2; text-indent: 0px; text-transform: none; widows: 2; word-spacing: 0px; -webkit-text-stroke-width: 0px; white-space: normal; background-color: rgb(255, 255, 255); text-decoration-thickness: initial; text-decoration-style: initial; text-decoration-color: initial;">Nomura Global Financial Products, Inc., Nomura
      Securities International, Inc. and Nomura International PLC are wholly owned subsidiaries of Nomura Holdings, Inc.</div>
  </div>
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</DOCUMENT>
</SEC-DOCUMENT>
