Total Operating Expenses (Tables)

6 Months Ended

Jun. 30, 2018

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Summary of Total Operating Expenses

A breakdown of total operating expenses is presented as follows:

Three-month period ended

June 30,

Six-month period ended

June 30,

2018

2017

2018

2017

(euros in thousands)

Manufacturing costs

5,580

2,236

9,858

5,611

IP and license costs

492

603

844

968

Personnel related R&D

2,107

1,771

3,808

3,303

Other research and development costs

4,344

3,810

8,311

5,545

Total research and development costs

12,523

8,420

22,821

15,427

Management and administration costs

2,639

3,492

5,491

7,694

Litigation costs

552

104

849

394

Other operating expenses

2,745

2,173

5,134

3,726

Total other expenses

3,297

2,277

5,983

4,120

Total operating expenses

18,459

14,189

34,295

27,241

Breakdown of Other Research and Development Costs

A breakdown of other research and development costs is presented as follows:

Three-month period ended

June 30,

Six-month period ended

June 30,

2018

2017

2018

2017

(euros in thousands)

Discovery and pre-clinical costs

1,078

1,698

1,763

2,076

Clinical costs

1,850

1,292

4,248

2,002

Other research and development costs

1,416

820

2,300

1,467

Total other research and development costs

4,344

3,810

8,311

5,545