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Total Operating Expenses (Tables) | 6 Months Ended
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Jun. 30, 2019
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Summary of Total Operating Expenses | The following table presents a breakdown of operating expenses:
|  | Three months ended June 30, |  |  | Six months ended June 30, |
|  | 2019 |  |  | 2018 |  |  | 2019 |  |  | 2018 |
|  | (euros in thousands) |
Manufacturing costs |  |  | 450 |  |  |  | 5,580 |  |  |  | 2,325 |  |  |  | 9,858 |
IP and license costs |  |  | 585 |  |  |  | 492 |  |  |  | 876 |  |  |  | 844 |
Personnel related R&D |  |  | 2,470 |  |  |  | 2,107 |  |  |  | 4,510 |  |  |  | 3,808 |
Other R&D costs |  |  | 6,479 |  |  |  | 4,344 |  |  |  | 12,644 |  |  |  | 8,311 |
Total R&D costs |  |  | 9,984 |  |  |  | 12,523 |  |  |  | 20,355 |  |  |  | 22,821 |
Management and administration costs |  |  | 3,119 |  |  |  | 2,639 |  |  |  | 5,055 |  |  |  | 5,491 |
Litigation costs |  |  | 59 |  |  |  | 552 |  |  |  | 123 |  |  |  | 849 |
Other operating expenses |  |  | 3,684 |  |  |  | 2,745 |  |  |  | 7,624 |  |  |  | 5,134 |
Total other expenses |  |  | 3,743 |  |  |  | 3,297 |  |  |  | 7,747 |  |  |  | 5,983 |
Total operating expenses |  |  | 16,846 |  |  |  | 18,459 |  |  |  | 33,157 |  |  |  | 34,295 |
Breakdown of Other Research and Development Costs | A breakdown of other R&D costs is presented as follows:
|  | Three months ended June 30, |  |  | Six months ended June 30, |
|  | 2019 |  |  | 2018 |  |  | 2019 |  |  | 2018 |
|  | (euros in thousands) |
Discovery and preclinical costs |  |  | 2,055 |  |  |  | 1,078 |  |  |  | 4,175 |  |  |  | 1,763 |
Clinical costs |  |  | 3,156 |  |  |  | 1,850 |  |  |  | 6,041 |  |  |  | 4,248 |
Other R&D costs |  |  | 1,268 |  |  |  | 1,416 |  |  |  | 2,428 |  |  |  | 2,300 |
Total other R&D costs |  |  | 6,479 |  |  |  | 4,344 |  |  |  | 12,644 |  |  |  | 8,311 |

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