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Shareholders' Equity (Tables) | 6 Months Ended
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Jun. 30, 2019
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Summary of Reconciliation of Common Shares Outstanding | The following is a tabular reconciliation of common shares outstanding for the six months ended June 30, 2019 and 2018.
|  | Six months ended June 30, |
|  | 2019 |  |  | 2018 |
Common Shares outstanding at January 1, |  |  | 23,358,977 |  |  |  | 19,429,848 |
Issued for cash |  |  | — |  |  |  | 3,099,997 |
Exercise of common share options |  |  | 9,980 |  |  |  | 34,041 |
Vesting of RSUs |  |  | 24,330 |  |  |  | 68,914 |
Common shares outstanding at June 30, |  |  | 23,393,287 |  |  |  | 22,632,800 |
Summary of Inputs Used in the Measurement of the Fair Values and the Related Fair Values at the Grant Dates | The inputs used in the measurement of the fair values and the related fair values at the grant dates for the options granted during the six months ended June 30, 2019 were:
|  | Key Management Personnel (euros) |  |  | All Other Personnel (euros) |
Fair value at grant date |  |  | 6.07 – 7.60 |  |  |  | 6.15 – 8.62 |
Share price at grant date |  |  | 9.83 – 12.49 |  |  |  | 9.83 – 14.19 |
Exercise price |  |  | 9.83 – 12.49 |  |  |  | 9.83 – 14.19 |
Expected volatility (weighted-average) |  |  | 87.58 | % |  |  | 87.11 | %
Contractual life |  |  | 10 years |  |  |  | 10 years |
Expected dividends |  |  | — | % |  |  | — | %
Risk-free interest rate (based on government bonds) |  |  | 2.13%—2.74 | % |  |  | 2.02%—2.65 | %
Summary of Reconciliation of Outstanding Share Options | The number of share options and the weighted average exercise prices of share options granted were as follows for the six months ended June 30, 2019:
|  | Weighted average exercise price (euros) |  | Number of options |
Outstanding at January 1, 2019 |  | 14.62 |  |  | 2,633,039 |
Forfeited during the six months |  | 14.07 |  |  | (223,631 | )
Expired during the six months |  | 15.95 |  |  | (126,589 | )
Exercised during the six months |  | 11.02 |  |  | (9,980 | )
Granted during the six months |  | 10.23 |  |  | 1,009,671 |
Outstanding at June 30, 2019 |  | 13.27 |  |  | 3,282,510 |
Exercisable at June 30, 2019 |  | 13.34 |  |  | 1,533,094 |
Summary of Number of Share Options Outstanding | The number of options outstanding by group of employees as of June 30, 2019, was as follows:
Group of employees entitled |  | June 30, 2019 |
Key management personnel |  |  | 2,580,281 |
All other employees |  |  | 702,229 |
Total |  |  | 3,282,510 |
Summary of Reconciliation of RSU's | During the six months ended June 30, 2019, the Company did not grant any new RSUs. The following table summarizes the Company’s RSU activity for the six months ended June 30, 2019:
|  | Weighted average grant price (euros) |  |  | Number of RSU’s |
Outstanding at January 1, 2019 |  |  | 20.03 |  |  |  | 101,302 |
Forfeited during the six months |  |  | — |  |  |  | — |
Vested during the six months |  |  | 20.03 |  |  |  | (24,330 | )
Granted during the six months |  |  | — |  |  |  | — |
Outstanding at June 30, 2019 |  |  | — |  |  |  | 76,972 |

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