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v3.24.3

Common Share - Additional Information (Details) |  |  |  |  |  |  | 1 Months Ended | 3 Months Ended | 9 Months Ended | 12 Months Ended |  |  |  |  |
--- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | ---
May 31, 2024 USD ($) | May 29, 2024 € / shares shares | Mar. 05, 2024 USD ($) $ / shares shares | Aug. 14, 2023 USD ($) | Aug. 09, 2023 € / shares shares | May 22, 2023 USD ($) | May 31, 2021 USD ($) | Jun. 30, 2023 USD ($) shares | Sep. 30, 2024 USD ($) | Sep. 30, 2023 USD ($) | Dec. 31, 2022 USD ($) shares | Sep. 30, 2024 € / shares | Sep. 30, 2024 USD ($) shares | May 29, 2024 $ / shares | Feb. 29, 2024 USD ($) | Dec. 31, 2023 € / shares | Dec. 31, 2023 USD ($) shares | Aug. 09, 2023 $ / shares
Class of Stock [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Common shares, value, issued |  |  |  |  |  |  |  |  |  |  |  |  | $ 6,919,000 |  |  |  | $ 5,883,000 |
Common shares, issued | shares |  |  |  |  |  |  |  |  |  |  |  |  | 68,426,779 |  |  |  | 57,825,879 |
Gross proceeds, before deducting sales agent commissions |  |  |  |  |  |  |  |  | $ 434,863,000 | $ 225,945,000 |  |  |  |  |  |  |  |
Common shares, par value | € / shares |  |  |  |  |  |  |  |  |  |  |  | € 0.09 |  |  |  | € 0.09 |  |
Sales Agreement |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Class of Stock [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Common shares, issued | shares |  |  |  |  |  |  |  |  |  |  | 2,720,846 |  |  |  |  |  |  |
Common shares, sold | shares |  |  |  |  |  |  |  | 3,272,280 |  |  |  |  |  |  |  |  |  |
Gross proceeds, before deducting sales agent commissions |  |  |  |  |  |  |  | $ 65,500,000 |  |  | $ 59,500,000 |  |  |  |  |  |  |
Sales agent commissions |  |  |  |  |  |  |  |  |  |  | $ 1,700,000 |  |  |  |  |  |  |
Net proceeds, after deducting sales agent fees, underwriting discounts and commissions |  |  |  |  |  | $ 124,900,000 |  | $ 63,800,000 |  |  |  |  |  |  |  |  |  |
Sales Agreement | Maximum |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Class of Stock [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Shares sale agreement authorized amount |  |  |  |  |  | $ 125,000,000 | $ 125,000,000 |  |  |  |  |  |  |  |  |  |  |
Underwriting commissions rate of gross proceeds of shares sold |  |  |  |  |  |  | 3.00% |  |  |  |  |  |  |  |  |  |  |
Underwriting Agreement |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Class of Stock [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Common shares, sold | shares |  |  |  |  | 6,818,182 |  |  |  |  |  |  |  |  |  |  |  |  |
Net proceeds, after deducting sales agent fees, underwriting discounts and commissions |  |  |  | $ 162,200,000 |  |  |  |  |  |  |  |  |  |  |  |  |  |
Sale of shares, price per share | $ / shares |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | $ 22
Common shares, par value | € / shares |  |  |  |  | € 0.09 |  |  |  |  |  |  |  |  |  |  |  |  |
Additional common shares at public offering price | shares |  |  |  |  | 1,022,727 |  |  |  |  |  |  |  |  |  |  |  |  |
Gilead Collaboration Agreement |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Class of Stock [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Common shares, sold | shares |  |  | 452,527 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Common shares stated purchase price per share | $ / shares |  |  | $ 55.2454 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Gross proceeds, before deducting sales agent commissions |  |  | $ 25,000,000 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
2024 Sales Agreement |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Class of Stock [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Common shares, issued | shares |  |  |  |  |  |  |  |  |  |  |  |  | 0 |  |  |  |  |
2024 Sales Agreement | Maximum |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Class of Stock [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Shares sale agreement authorized amount |  |  |  |  |  |  |  |  |  |  |  |  |  |  | $ 300,000,000 |  |  |
Underwriting commissions rate of gross proceeds of shares sold |  |  |  |  |  |  |  |  | 3.00% |  |  |  |  |  |  |  |  |
2024 Underwriting Agreement |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Class of Stock [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Common shares, sold | shares |  | 7,550,000 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Net proceeds, after deducting sales agent fees, underwriting discounts and commissions | $ 434,900,000 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Sale of shares, price per share | $ / shares |  |  |  |  |  |  |  |  |  |  |  |  |  | $ 53 |  |  |  |
Common shares, par value | € / shares |  | € 0.09 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Additional common shares at public offering price | shares |  | 1,132,500 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |

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