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Pay vs Performance Disclosure - USD ($)
 12 Months Ended
Dec. 31, 2023
Dec. 31, 2022
Dec. 31, 2021
Dec. 31, 2020
Pay vs Performance Disclosure        
Pay vs Performance Disclosure, Table
PAY VERSUS PERFORMANCE
 
Pay Versus Performance Table
The following table sets forth information concerning the compensation of our NEOs for each of the fiscal years ended December 31, 2020, 2021, 2022 and 2023, and our financial performance for each such fiscal year:
 
             
                      
Year-end
value of $100
invested on 12/31/2019 in:
     
Year
  
Summary
Compensation
Table Total for
PEO (1)
$
  
Compensation
Actually Paid to
the PEO
(1)(2)(3)
$
  
Average
Summary
Compensation
Table Total for
Non-PEO NEOs
(4)
$
  
Average
Compensation
Actually Paid to
Non-PEO NEOs

(2)(3)(4)
$
  
MRUS
$
  
NASDAQ
Biotech
Index
$
  
Net
Income
(in
millions)
$
2023
   4,671,327   11,843,191   2,875,609   4,616,893   195.31   118.87   -154.9
2022
   5,744,794   -2,256,931   1,997,552   -53,411   109.87   113.65   -131.2
2021
   7,540,935   11,523,096   2,031,414   3,116,021   225.85   126.45   -66.8
2020
   5,049,022   5,589,212   1,453,520   1,380,032   124.50   126.42   -85.5
 
(1) The PEO for all four fiscal years is Sven (Bill) Ante Lundberg.
(2) Deductions from, and additions to, total compensation in the Summary Compensation Table by year to calculate Compensation Actually Paid include:
 
   
2023
    
2022
    
2021
    
2020
  
   
PEO
    
Average
Non-CEO
NEOs
    
PEO
    
Average
Non-CEO
NEOs
    
PEO
    
Average
Non-CEO
NEOs
    
PEO
    
Average
Non-CEO
NEOs
  
Total Compensation from Summary Compensation Table
  
$
4,671,327
 
  
$
2,875,609
 
  
$
5,744,794
 
  
$
1,997,552
 
  
$
7,540,935
 
  
$
2,031,414
 
  
$
5,049,022
 
  
$
1,453,520
  
Adjustments for Equity Awards
                
Adjustment for grant date values in the Summary Compensation Table   $ (3,556,800 )    $ (2,244,060 )    $ (4,791,732 )    $ (1,367,010 )    $ (6,550,400 )    $ (1,389,468 )    $ (4,062,203 )    $ (840,427 ) 
Year-end
fair value of unvested awards granted in the current year		   $ 7,479,906     $ 3,359,964     $ 2,381,092     $ 669,935     $ 7,516,254     $ 1,531,846     $ 4,598,303     $ 654,243  
Year-over-year difference of
year-end
fair values for unvested awards granted in prior years		   $ 2,154,165     $ 439,173     $ (4,187,745 )    $ (949,302 )    $ 2,568,931     $ 739,590     $ 14,919     $ 129,725  
Difference in fair values between prior
year-end
fair values and vest		   $ 1,094,592     $ 186,206     $ (1,403,339 )    $ (404,586 )    $ 447,375     $ 202,639     $ (10,829 )    $ (17,029 ) 
 
 
 
    
 
 
    
 
 
    
 
 
    
 
 
    
 
 
    
 
 
    
 
 
  
Total Adjustments for Equity Awards
  
$
7,171,864
 
  
$
1,741,284
 
  
$
(8,001,725
) 
  
$
(2,050,963
) 
  
$
3,982,161
 
  
$
1,084,607
 
  
$
540,190
 
  
$
(73,488
)
 
Compensation Actually Paid (as calculated)
  
$
11,843,191
 
  
$
4,616,893
 
  
$
(2,256,931
) 
  
$
(53,411
) 
  
$
11,523,096
 
  
$
3,116,021
 
  
$
5,589,212
 
  
$
1,380,032
  
 
 
 
    
 
 
    
 
 
    
 
 
    
 
 
    
 
 
    
 
 
    
 
 
  
 
(3a) The following summarizes the valuation assumptions used for stock option awards included as part of Compensation Actually Paid:
 
  •  
Expected life of each stock option is based on the “simplified method” using an average of the remaining vest and remaining term, as of the vest/FYE date.
 
  •  
Strike price is based on each grant date closing price and asset price is based on each vest/FYE closing price.
 
  •  
Risk free rate is based on the Treasury Constant Maturity rate closest to the remaining expected life as of the vest/FYE date.
 
  •  
Historical volatility is based on daily price history for each expected life (years) prior to each vest/FYE date. Closing prices provided by S&P Capital IQ are adjusted for dividends and splits.
 
  •  
Represents annual dividend yield on each vest/FYE date.
(3b) The following table illustrates the valuation assumptions as of the vesting date for awards that vested in each of 2023, 2022, 2021, 2020:
 
   
For Stock Options Vesting in
      
For Restricted
Share and
Restricted
Stock Units
Vesting in
  
   
2023
  
2022
  
2021
  
2020
      
2021
    
2020
  
Expected volatility
  
67.42% - 76.20%
  
68.94% - 76.55%
  
66.41% - 74.18%
  
66.60% - 73.37%
      
Expected dividend yield
   0%   0%   0%   0%  
Weighted Average Fair Value at vesting
   $ 17.53     $ 14.14  
Expected term, in years
   2.8 - 4.5 years   3.1 - 4.6 years   3.0 - 4.6 years   3.0 - 4.8 years      
Risk-free interest rate
   3.48% - 5.01%   0.97% - 4.56%   0.17% - 1.27%   0.11% - 1.69%      
 
(4)
Non-PEO
NEOs reflect the average Summary Compensation Table total compensation and average Compensation Actually Paid for the following executives by year:
2023: Hui Liu, Peter Silverman, Andrew Joe, Greg Perry
2022: Hui Liu, Peter Silverman, Andrew Joe
2021: Hui Liu, Peter Silverman
2020: Hui Liu, Peter Silverman
     
Named Executive Officers, Footnote
(4)
Non-PEO
NEOs reflect the average Summary Compensation Table total compensation and average Compensation Actually Paid for the following executives by year:
2023: Hui Liu, Peter Silverman, Andrew Joe, Greg Perry
2022: Hui Liu, Peter Silverman, Andrew Joe
2021: Hui Liu, Peter Silverman
2020: Hui Liu, Peter Silverman
     
PEO Total Compensation Amount $ 4,671,327 $ 5,744,794 $ 7,540,935 $ 5,049,022
PEO Actually Paid Compensation Amount $ 11,843,191 (2,256,931) 11,523,096 5,589,212
Adjustment To PEO Compensation, Footnote
   
2023
    
2022
    
2021
    
2020
  
   
PEO
    
Average
Non-CEO
NEOs
    
PEO
    
Average
Non-CEO
NEOs
    
PEO
    
Average
Non-CEO
NEOs
    
PEO
    
Average
Non-CEO
NEOs
  
Total Compensation from Summary Compensation Table
  
$
4,671,327
 
  
$
2,875,609
 
  
$
5,744,794
 
  
$
1,997,552
 
  
$
7,540,935
 
  
$
2,031,414
 
  
$
5,049,022
 
  
$
1,453,520
  
Adjustments for Equity Awards
                
Adjustment for grant date values in the Summary Compensation Table   $ (3,556,800 )    $ (2,244,060 )    $ (4,791,732 )    $ (1,367,010 )    $ (6,550,400 )    $ (1,389,468 )    $ (4,062,203 )    $ (840,427 ) 
Year-end
fair value of unvested awards granted in the current year		   $ 7,479,906     $ 3,359,964     $ 2,381,092     $ 669,935     $ 7,516,254     $ 1,531,846     $ 4,598,303     $ 654,243  
Year-over-year difference of
year-end
fair values for unvested awards granted in prior years		   $ 2,154,165     $ 439,173     $ (4,187,745 )    $ (949,302 )    $ 2,568,931     $ 739,590     $ 14,919     $ 129,725  
Difference in fair values between prior
year-end
fair values and vest		   $ 1,094,592     $ 186,206     $ (1,403,339 )    $ (404,586 )    $ 447,375     $ 202,639     $ (10,829 )    $ (17,029 ) 
 
 
 
    
 
 
    
 
 
    
 
 
    
 
 
    
 
 
    
 
 
    
 
 
  
Total Adjustments for Equity Awards
  
$
7,171,864
 
  
$
1,741,284
 
  
$
(8,001,725
) 
  
$
(2,050,963
) 
  
$
3,982,161
 
  
$
1,084,607
 
  
$
540,190
 
  
$
(73,488
)
 
Compensation Actually Paid (as calculated)
  
$
11,843,191
 
  
$
4,616,893
 
  
$
(2,256,931
) 
  
$
(53,411
) 
  
$
11,523,096
 
  
$
3,116,021
 
  
$
5,589,212
 
  
$
1,380,032
  
 
 
 
    
 
 
    
 
 
    
 
 
    
 
 
    
 
 
    
 
 
    
 
 
  
      
Non-PEO NEO Average Total Compensation Amount $ 2,875,609 1,997,552 2,031,414 1,453,520
Non-PEO NEO Average Compensation Actually Paid Amount $ 4,616,893 (53,411) 3,116,021 1,380,032
Adjustment to Non-PEO NEO Compensation Footnote
   
2023
    
2022
    
2021
    
2020
  
   
PEO
    
Average
Non-CEO
NEOs
    
PEO
    
Average
Non-CEO
NEOs
    
PEO
    
Average
Non-CEO
NEOs
    
PEO
    
Average
Non-CEO
NEOs
  
Total Compensation from Summary Compensation Table
  
$
4,671,327
 
  
$
2,875,609
 
  
$
5,744,794
 
  
$
1,997,552
 
  
$
7,540,935
 
  
$
2,031,414
 
  
$
5,049,022
 
  
$
1,453,520
  
Adjustments for Equity Awards
                
Adjustment for grant date values in the Summary Compensation Table   $ (3,556,800 )    $ (2,244,060 )    $ (4,791,732 )    $ (1,367,010 )    $ (6,550,400 )    $ (1,389,468 )    $ (4,062,203 )    $ (840,427 ) 
Year-end
fair value of unvested awards granted in the current year		   $ 7,479,906     $ 3,359,964     $ 2,381,092     $ 669,935     $ 7,516,254     $ 1,531,846     $ 4,598,303     $ 654,243  
Year-over-year difference of
year-end
fair values for unvested awards granted in prior years		   $ 2,154,165     $ 439,173     $ (4,187,745 )    $ (949,302 )    $ 2,568,931     $ 739,590     $ 14,919     $ 129,725  
Difference in fair values between prior
year-end
fair values and vest		   $ 1,094,592     $ 186,206     $ (1,403,339 )    $ (404,586 )    $ 447,375     $ 202,639     $ (10,829 )    $ (17,029 ) 
 
 
 
    
 
 
    
 
 
    
 
 
    
 
 
    
 
 
    
 
 
    
 
 
  
Total Adjustments for Equity Awards
  
$
7,171,864
 
  
$
1,741,284
 
  
$
(8,001,725
) 
  
$
(2,050,963
) 
  
$
3,982,161
 
  
$
1,084,607
 
  
$
540,190
 
  
$
(73,488
)
 
Compensation Actually Paid (as calculated)
  
$
11,843,191
 
  
$
4,616,893
 
  
$
(2,256,931
) 
  
$
(53,411
) 
  
$
11,523,096
 
  
$
3,116,021
 
  
$
5,589,212
 
  
$
1,380,032
  
 
 
 
    
 
 
    
 
 
    
 
 
    
 
 
    
 
 
    
 
 
    
 
 
  
      
Compensation Actually Paid vs. Total Shareholder Return
LOGO
     
Compensation Actually Paid vs. Net Income
LOGO
     
Total Shareholder Return Vs Peer Group
LOGO
     
Total Shareholder Return Amount $ 195.31 109.87 225.85 124.5
Peer Group Total Shareholder Return Amount 118.87 113.65 126.45 126.42
Net Income (Loss) $ (154,900,000) $ (131,200,000) $ (66,800,000) $ (85,500,000)
PEO Name Sven (Bill) Ante Lundberg.      
Stock Options Vesting Expected Volatility Maximum 76.20% 76.55% 74.18% 73.37%
Stock Options Vesting Expected Volatility Minimum 67.42% 68.94% 66.41% 66.60%
Stock Options Vesting Expected Dividend Yield 0.00% 0.00% 0.00% 0.00%
Stock Options Vesting Expected Term In Years Maximum 4 years 6 months 4 years 7 months 6 days 4 years 7 months 6 days 4 years 9 months 18 days
Stock Options Vesting Expected Term In Years Minimum 2 years 9 months 18 days 3 years 1 month 6 days 3 years 3 years
Stock Options Vesting RiskFree Interest Rate Maximum 5.01% 4.56% 1.27% 1.69%
Stock Options Vesting RiskFree Interest Rate Minimum 3.48% 0.97% 0.17% 0.11%
Restricted Share And Restricted Stock Units Vesting Weighted Average Fair Value At Vesting     $ 17.53 $ 14.14
PEO | Adjustment For Grant Date Values [Member]        
Pay vs Performance Disclosure        
Adjustment to Compensation, Amount $ (3,556,800) $ (4,791,732) $ (6,550,400) $ (4,062,203)
PEO | Year-End Fair Value Of Unvested Awards Granted In The Current Year [Member]        
Pay vs Performance Disclosure        
Adjustment to Compensation, Amount 7,479,906 2,381,092 7,516,254 4,598,303
PEO | Year-Over-Year Difference Of YearEnd Fair Values For Unvested Awards Granted In Prior Years [Member]        
Pay vs Performance Disclosure        
Adjustment to Compensation, Amount 2,154,165 (4,187,745) 2,568,931 14,919
PEO | Difference In Fair Values Between Prior YearEnd Fair Values And Vest Date Fair Values For Awards Granted In Prior Years [Member]        
Pay vs Performance Disclosure        
Adjustment to Compensation, Amount 1,094,592 (1,403,339) 447,375 (10,829)
PEO | Total Adjustments [Member]        
Pay vs Performance Disclosure        
Adjustment to Compensation, Amount 7,171,864 (8,001,725) 3,982,161 540,190
Non-PEO NEO | Adjustment For Grant Date Values [Member]        
Pay vs Performance Disclosure        
Adjustment to Compensation, Amount (2,244,060) (1,367,010) (1,389,468) (840,427)
Non-PEO NEO | Year-End Fair Value Of Unvested Awards Granted In The Current Year [Member]        
Pay vs Performance Disclosure        
Adjustment to Compensation, Amount 3,359,964 669,935 1,531,846 654,243
Non-PEO NEO | Year-Over-Year Difference Of YearEnd Fair Values For Unvested Awards Granted In Prior Years [Member]        
Pay vs Performance Disclosure        
Adjustment to Compensation, Amount 439,173 (949,302) 739,590 129,725
Non-PEO NEO | Difference In Fair Values Between Prior YearEnd Fair Values And Vest Date Fair Values For Awards Granted In Prior Years [Member]        
Pay vs Performance Disclosure        
Adjustment to Compensation, Amount 186,206 (404,586) 202,639 (17,029)
Non-PEO NEO | Total Adjustments [Member]        
Pay vs Performance Disclosure        
Adjustment to Compensation, Amount $ 1,741,284 $ (2,050,963) $ 1,084,607 $ (73,488)