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Condensed Consolidated Statements of Comprehensive Income/(Loss) (USD $)
 3 Months Ended 9 Months Ended
Sep. 30, 2014
Sep. 30, 2013
Sep. 30, 2014
Sep. 30, 2013
Revenue:        
Product revenue $ 15,152,510 $ 12,184,215 $ 45,038,275 $ 37,132,094
Royalty and other revenue 125,675 6,637,838 2,116,841 15,654,919
Total revenue 15,278,185 18,822,053 47,155,116 52,787,013
Operating expenses:        
Cost of product revenue 6,931,094 5,659,832 19,937,739 17,854,249
Cost of royalty revenue   723,777   1,943,370
Research and development 1,649,864 1,429,529 4,280,987 5,919,265
Selling, general and administrative 4,470,682 2,902,048 12,180,127 9,334,087
Contingent consideration - fair value adjustments 10,315 65,108 126,335 46,521
Total operating expenses 13,061,955 10,780,294 36,525,188 35,097,492
Income from operations 2,216,230 8,041,759 10,629,928 17,689,521
Investment income 63,924 76,046 250,659 203,170
Interest expense (11,489) (11,704) (38,354) (37,637)
Other income (expense) (14,113) 36,678 53,671 (56,504)
Income before income taxes 2,254,552 8,142,779 10,895,904 17,798,550
Income tax provision 788,316 2,254,505 2,327,145 5,032,853
Net income 1,466,236 5,888,274 8,568,759 12,765,697
Earnings per share:        
Basic $ 0.04 $ 0.18 $ 0.27 $ 0.40
Diluted $ 0.04 $ 0.18 $ 0.26 $ 0.40
Weighted average shares outstanding:        
Basic 32,677,003 31,858,103 32,292,588 31,583,063
Diluted 33,327,377 32,551,586 33,099,599 32,282,702
Other comprehensive income:        
Unrealized gain (loss) on investments 33,718 2,276 45,784 (4,345)
Foreign currency translation (loss) (3,157,242) 1,407,860 (4,762,998) 267,364
Comprehensive income/(loss) $ (1,657,288) $ 7,298,410 $ 3,851,545 $ 13,028,716