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CONSOLIDATED STATEMENTS OF OPERATIONS AND COMPREHENSIVE INCOME - USD ($)
$ in Thousands
 12 Months Ended
Dec. 31, 2015
Dec. 31, 2014
Dec. 31, 2013
Revenue:      
Product revenue $ 83,537 $ 60,431 $ 47,482
Royalty and other revenue   3,117 20,687
Total revenue 83,537 63,548 68,169
Operating expenses:      
Cost of product revenue 35,251 28,022 22,481
Cost of royalty and other revenue     2,682
Research and development 5,740 5,609 7,341
Selling, general and administrative 24,699 17,154 12,701
Contingent consideration - fair value adjustments 4,083 2,072 91
Total operating expenses 69,773 52,857 45,296
Income from operations 13,764 10,691 22,873
Investment income 136 309 301
Interest expense (32) (50) (50)
Other income (expense) (445) 188 (110)
Income before income taxes 13,423 11,138 23,014
Income tax (benefit) provision 4,078 2,968 6,921
Net income $ 9,345 $ 8,170 $ 16,093
Earnings per share:      
Basic $ 0.28 $ 0.25 $ 0.51
Diluted $ 0.28 $ 0.25 $ 0.50
Weighted average shares outstanding:      
Basic 32,881,940 32,497,657 31,667,015
Diluted 33,577,091 33,263,667 32,406,641
Other comprehensive income:      
Unrealized (loss) gain on investments $ 22 $ (28) $ (19)
Foreign currency translation (loss) gain (2,815) (7,743) 106
Comprehensive income $ 6,552 $ 399 $ 16,180