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Revenue Recognition - Additional Information (Detail) - USD ($) |  |  | 3 Months Ended
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Sep. 03, 2014 | Jan. 30, 2014 | Mar. 31, 2016 | Mar. 31, 2014
Revenue Recognition, Multiple-deliverable Arrangements [Line Items] |  |  |  |
Non-refundable up-front payment |  |  | $ 2,000,000 |
Payment to be received upon signing of agreement |  |  | 125,675 |
Revenue recognized |  |  | 2,115,000 |
Revenue recognized under revenue recognition, up front payment |  |  |  | $ 2,000,000
Clinical Development |  |  |  |
Revenue Recognition, Multiple-deliverable Arrangements [Line Items] |  |  |  |
Milestone Payment |  |  | 60,000,000 |
Potential milestone payments to be received |  |  | 60,000,000 |
Initial Commercial Sales |  |  |  |
Revenue Recognition, Multiple-deliverable Arrangements [Line Items] |  |  |  |
Potential milestone payments to be received |  |  | 100,000,000 |
BioMarin Pharmaceutical, Inc. | Asset Purchase Agreement |  |  |  |
Revenue Recognition, Multiple-deliverable Arrangements [Line Items] |  |  |  |
Upfront payment received under purchase agreement |  | $ 2,000,000 |  |
Potential milestone payments to be received |  |  | 160,000,000 |
Provision for refund |  |  | $ 0 |
BioMarin Pharmaceutical, Inc. | Clinical Development | Asset Purchase Agreement |  |  |  |
Revenue Recognition, Multiple-deliverable Arrangements [Line Items] |  |  |  |
Percentage relate to clinical development from Milestone payment |  |  | 37.00% |
BioMarin Pharmaceutical, Inc. | Initial Commercial Sales | Asset Purchase Agreement |  |  |  |
Revenue Recognition, Multiple-deliverable Arrangements [Line Items] |  |  |  |
Percentage relate to clinical development from Milestone payment |  |  | 63.00% |
BioMarin Pharmaceutical, Inc. | Technology Transfer Payments | Asset Purchase Agreement |  |  |  |
Revenue Recognition, Multiple-deliverable Arrangements [Line Items] |  |  |  |
Milestone Payment | $ 125,675 |  |  |

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- Definition Amount of deferred revenue recognized for transactions arising during the current reporting period. Deferred revenue is a liability as of the balance sheet date related to a revenue producing activity for which revenue has not yet been recognized. Generally, an Entity records deferred revenue when it receives consideration from a customer before achieving certain criteria that must be met for revenue to be recognized in conformity with GAAP. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 605 -SubTopic 10 -Section S99 -Paragraph 1 -Subparagraph (SAB TOPIC 13.A.4(a).Q1) -URI http://asc.fasb.org/extlink&oid=27012821&loc=d3e214044-122780 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher SEC -Name Staff Accounting Bulletin (SAB) -Number Topic 13 -Section A + Details
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