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Revenue Recognition - Additional Information (Detail) $ in Millions | 3 Months Ended
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Mar. 31, 2017 USD ($)
Clinical Development |
Revenue Recognition, Multiple-deliverable Arrangements [Line Items] |
Potential milestone payments to be received | $ 60
Milestone payment substantive | 60
Initial Commercial Sales |
Revenue Recognition, Multiple-deliverable Arrangements [Line Items] |
Potential milestone payments to be received | 100
BioMarin Pharmaceutical, Inc. | Asset Purchase Agreement |
Revenue Recognition, Multiple-deliverable Arrangements [Line Items] |
Potential milestone payments to be received | $ 160

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