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Revenue Recognition - Additional Information (Detail) $ in Millions	9 Months Ended
	Sep. 30, 2017 USD ($)
Clinical Development
Revenue Recognition, Multiple-deliverable Arrangements [Line Items]
Potential milestone payments to be received	$ 60
Milestone payment substantive	60
Initial Commercial Sales
Revenue Recognition, Multiple-deliverable Arrangements [Line Items]
Potential milestone payments to be received	100
BioMarin Pharmaceutical, Inc. | Asset Purchase Agreement
Revenue Recognition, Multiple-deliverable Arrangements [Line Items]
Potential milestone payments to be received	$ 160

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- Definition

Potential additional milestone payments associated with potential regulatory approvals.

+ References

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- Definition

The amount of consideration recognized during the period for the milestone or milestones.

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 605
-SubTopic 28
-Section 50
-Paragraph 2
-Subparagraph (e)
-URI http://asc.fasb.org/extlink&oid=68058744&loc=SL6892177-166501

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- Definition

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+ References

No definition available.

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