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CONSOLIDATED STATEMENTS OF OPERATIONS AND COMPREHENSIVE INCOME - USD ($)
$ in Thousands
 12 Months Ended
Dec. 31, 2017
Dec. 31, 2016
Dec. 31, 2015
Revenue:      
Product revenue $ 141,089 $ 104,441 $ 83,537
Royalty and other revenue 147 100  
Total revenue 141,236 104,541 83,537
Operating expenses:      
Cost of product revenue 67,050 47,117 35,251
Research and development 8,672 7,355 5,740
Selling, general and administrative 51,509 30,853 24,699
Contingent consideration - fair value adjustments   3,242 4,083
Total operating expenses 127,231 88,567 69,773
Income from operations 14,005 15,974 13,764
Investment income 371 346 136
Interest expense (6,441) (3,768) (32)
Other income (expense) (687) (860) (445)
Income before income taxes 7,248 11,692 13,423
Income tax provision (benefit) (21,105) 11 4,078
Net income $ 28,353 $ 11,681 $ 9,345
Earnings per share:      
Basic $ 0.74 $ 0.35 $ 0.28
Diluted $ 0.72 $ 0.34 $ 0.28
Weighted average shares outstanding:      
Basic 38,233,527 33,572,883 32,881,940
Diluted 39,150,374 34,098,898 33,577,091
Other comprehensive income:      
Unrealized gain (loss) on investments $ 5 $ 6 $ 22
Foreign currency translation gain (loss) 7,381 (5,189) (2,815)
Comprehensive income $ 35,739 $ 6,498 $ 6,552