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Commitments and Contingencies - Additional Information (Detail)
$ in Thousands
1 Months Ended 3 Months Ended 12 Months Ended
Mar. 31, 2014
USD ($)
ft²
Jul. 31, 2011
USD ($)
ft²
Dec. 31, 2017
USD ($)
Sep. 30, 2017
USD ($)
Jun. 30, 2017
USD ($)
Mar. 31, 2017
USD ($)
Dec. 31, 2016
USD ($)
Sep. 30, 2016
USD ($)
Jun. 30, 2016
USD ($)
Mar. 31, 2016
USD ($)
Dec. 31, 2017
USD ($)
ft²
Building
Dec. 31, 2016
USD ($)
Dec. 31, 2015
USD ($)
Mar. 31, 2008
ft²
Mar. 31, 2007
ft²
Mar. 31, 2001
ft²
Commitments and Contingencies [Line Items]                                
Lease agreement, term 8 years 1 month 11 years                       2 years 5 years 10 years
Lease agreement, space | ft²   55,694                 45,000     7,350 2,500 25,000
Lease agreement, expiration date   May 31, 2023                 Dec. 31, 2021          
Lease agreement, letter of credit issued   $ 200                            
Lease agreement, commencement date Aug. 01, 2014                              
Future minimum rental commitment, 2018     $ 3,611               $ 3,611          
Future minimum rental commitment, 2019     3,383               3,383          
Future minimum rental commitment, 2020     3,077               3,077          
Future minimum rental commitment, 2021     2,750               2,750          
Future minimum rental commitment, 2022     1,464               $ 1,464          
Lease termination description                     The Company terminated the lease on the 7,350 square feet of space in the first quarter of 2015.          
Lease agreement, number buildings leased | Building                     4          
Operating leases, rent expense                     $ 3,367 $ 2,644 $ 2,619      
Operating leases, deferred rent liabilities     1,656       $ 1,792       1,656 1,792 1,899      
Research and development expenses     3,069 $ 2,001 $ 1,860 $ 1,742 $ 2,040 $ 1,886 $ 1,890 $ 1,539 8,672 7,355 5,740      
Purchase orders, supply agreements and other contractual obligations     15,512               15,512          
Licensing Agreements                                
Commitments and Contingencies [Line Items]                                
Research and development expenses                     161 $ 5 $ 7      
Before Amendment                                
Commitments and Contingencies [Line Items]                                
Lease agreement, space | ft² 55,694                              
Security deposit $ 200                              
After Amendment                                
Commitments and Contingencies [Line Items]                                
Lease agreement, space | ft² 75,594                              
Security deposit $ 450                              
Future minimum rental commitment, 2018     1,371               1,371          
Future minimum rental commitment, 2019     1,371               1,371          
Future minimum rental commitment, 2020     1,371               1,371          
Future minimum rental commitment, 2021     1,371               1,371          
Future minimum rental commitment, 2022     1,251               1,251          
Expansion Space                                
Commitments and Contingencies [Line Items]                                
Lease agreement, space | ft² 19,900                              
Annual rent expense $ 361                              
Renewal Term                                
Commitments and Contingencies [Line Items]                                
Future minimum rental commitment, 2018     1,087               1,087          
Future minimum rental commitment, 2019     1,087               1,087          
Future minimum rental commitment, 2020     1,087               1,087          
Future minimum rental commitment, 2021     $ 1,087               $ 1,087