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Stock-Based Compensation (Tables) | 9 Months Ended
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Sep. 30, 2018
Stock-Based Compensation Expense | The following table presents stock-based compensation expense included in the Company’s consolidated statements of comprehensive income (amounts in thousands):
|  | Three Months Ended September 30, |  |  | Nine Months Ended September 30, |
|  | 2018 |  |  | 2017 |  |  | 2018 |  |  | 2017 |
Cost of product revenue |  | $ | 277 |  |  | $ | 197 |  |  | $ | 777 |  |  | $ | 491 |
Research and development |  |  | 253 |  |  |  | 127 |  |  |  | 650 |  |  |  | 338 |
Selling, general and administrative |  |  | 2,249 |  |  |  | 1,493 |  |  |  | 6,245 |  |  |  | 4,016 |
Total |  | $ | 2,779 |  |  | $ | 1,817 |  |  | $ | 7,672 |  |  | $ | 4,845 |
Summary of Option Activity | Information regarding option activity for the nine-month period ended September 30, 2018 under the Plans is summarized below:
|  | Options Outstanding |  |  | Weighted- Average Exercise Price Per Share |  |  | Weighted- Average Remaining Contractual Term (in years) |  |  | (in thousands) Aggregate Intrinsic Value |
Options outstanding at December 31, 2017 |  |  | 734,940 |  |  | $ | 20.80 |  |  |  |  |  |  |  |  |
Granted |  |  | 439,678 |  |  |  | 34.79 |  |  |  |  |  |  |  |  |
Exercised |  |  | (131,718 | ) |  |  | 18.02 |  |  |  |  |  |  |  |  |
Forfeited/cancelled |  |  | (9,588 | ) |  |  | 29.71 |  |  |  |  |  |  |  |  |
Options outstanding at September 30, 2018 |  |  | 1,033,312 |  |  | $ | 26.99 |  |  |  | 7.38 |  |  | $ | 29,421 |
Options exercisable at September 30, 2018 |  |  | 444,446 |  |  | $ | 18.73 |  |  |  | 5.29 |  |  | $ | 16,325 |
Vested and expected to vest at September 30, 2018 (1) |  |  | 986,509 |  |  | $ | 26.64 |  |  |  | 7.29 |  |  | $ | 28,429 |
| (1) | Represents the number of vested options as of September 30, 2018 plus the number of unvested options expected to vest as of September 30, 2018 based on the unvested outstanding options at September 30, 2018 adjusted for estimated forfeiture rates of 8% for awards granted to non-executive level employees and 3% for awards granted to executive level employees.
RSU and Performance Stock Units |
Summary of RSU and Performance Stock Unit Activity | Information regarding RSU and performance stock unit activity for the nine-month period ended September 30, 2018 under the Plans is summarized below:
|  | Units Outstanding |  |  | Weighted- Average Remaining Contractual Term (in years) |  |  | (in thousands) Aggregate Intrinsic Value |
Restricted and performance stock units outstanding at December 31, 2017 |  |  | 505,235 |  |  |  |  |  |  |  |  |
Granted |  |  | 385,461 |  |  |  |  |  |  |  |  |
Vested |  |  | (134,590 | ) |  |  |  |  |  |  |  |
Forfeited/cancelled |  |  | (48,390 | ) |  |  |  |  |  |  |  |
Restricted stock units outstanding at September 30, 2018 |  |  | 707,716 |  |  |  | 3.94 |  |  | $ | 39,250 |
Vested and expected to vest at September 30, 2018 (1) |  |  | 649,985 |  |  |  | 3.43 |  |  | $ | 36,048 |
| (1) | Represents the number of unvested RSUs expected to vest as of September 30, 2018 based on the unvested outstanding RSUs at September 30, 2018 adjusted for estimated forfeiture rates of 8% for awards granted to non-executive level employees and 3% for awards granted to executive level employees.

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