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Commitments and Contingencies - Additional Information (Detail) $ in Thousands	1 Months Ended			12 Months Ended
	Nov. 30, 2018 ft²	Jan. 31, 2018 ft²	Mar. 31, 2014 USD ($) ft²	Dec. 31, 2018 USD ($) ft² Building l	Dec. 31, 2017 USD ($) ft²	Dec. 31, 2016 USD ($)
Commitments and Contingencies [Line Items]
Lease agreement, expiration date				Dec. 31, 2021
Lease agreement, space | ft²		63,761		45,000
Lease agreement, term			8 years 1 month
Lease agreement, commencement date			Aug. 01, 2014
Future minimum rental commitment, 2019				$ 4,021
Future minimum rental commitment, 2020				3,599
Future minimum rental commitment, 2021				3,263
Future minimum rental commitment, 2022				2,213
Future minimum rental commitment, 2023				$ 1,316
Lease agreement, number buildings leased | Building				4
Operating leases, rent expense				$ 4,400	$ 3,400	$ 2,600
Operating leases, deferred rent liabilities				4,100	1,700	1,800
Research and development expenses				15,821	$ 8,672	$ 7,355
Purchase orders, supply agreements and other contractual obligations				$ 29,000
Maximum [Member]
Commitments and Contingencies [Line Items]
Bioreactors used in perfusion cell culture applications | l				2,000
Minimum [Member]
Commitments and Contingencies [Line Items]
Bioreactors used in perfusion cell culture applications | l				50
NGL Impact A [Member] | Research and Development Arrangement [Member]
Commitments and Contingencies [Line Items]
Payments to Navigo in connection with this program, which are recorded to research and development expenses				$ 2,400
Spectrum Inc.
Commitments and Contingencies [Line Items]
Lease agreement, expiration date				Nov. 30, 2025	Jul. 15, 2020
Lease agreement, space | ft²	15,000				54,000
Before Amendment
Commitments and Contingencies [Line Items]
Lease agreement, space | ft²			56,000
Security deposit			$ 200
After Amendment
Commitments and Contingencies [Line Items]
Lease agreement, space | ft²			76,000
Security deposit			$ 500
Future minimum rental commitment, 2019				$ 1,400
Future minimum rental commitment, 2020				1,400
Future minimum rental commitment, 2021				1,400
Future minimum rental commitment, 2022				1,300
Future minimum rental commitment, 2023				400
Expansion Space
Commitments and Contingencies [Line Items]
Lease agreement, space | ft²			19,900
Annual rent expense			$ 400
Renewal Term
Commitments and Contingencies [Line Items]
Future minimum rental commitment, 2019				900
Future minimum rental commitment, 2020				900
Future minimum rental commitment, 2021				$ 900

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