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Stockholders' Equity - Additional Information (Detail) - USD ($) $ / shares in Units, $ in Thousands |  |  |  | 12 Months Ended |
--- | --- | --- | --- | --- | ---
Dec. 08, 2020 | Jul. 19, 2019 | May 03, 2019 | Dec. 31, 2021 | Dec. 31, 2020 | Dec. 31, 2019 | Dec. 31, 2018
Stockholders Equity Note Disclosure [Line Items] |  |  |  |  |  |  |
Common stock, shares issued | 1,725,000 | 1,587,000 | 3,144,531 | 55,321,457 | 54,760,837 |  |
Common stock issue price per share | $ 181.00 | $ 87.00 | $ 64.00 |  |  |  |
Exercised number of shares |  |  |  | 98,428 |  |  |
Net proceeds from public offering | $ 297,800 | $ 131,100 | $ 189,600 |  | $ 297,775 | $ 320,713 |
Stock-based compensation expense |  |  |  | $ 27,500 | $ 17,007 | 12,847 |
Stock options, outstanding |  |  |  | 625,107 | 696,711 |  |
Restricted stock units, outstanding |  |  |  | 606,685 | 665,540 |  |
Aggregate intrinsic value of stock options exercised |  |  |  | $ 20,300 | $ 36,600 | $ 5,500 |
Weighted average grant date fair value of share-based awards granted |  |  |  | $ 88.01 | $ 53.06 | $ 31.27 |
Total fair value of stock options vested |  |  |  | $ 3,000 | $ 2,800 | $ 3,100 |
Total unrecognized compensation cost |  |  |  | $ 59,200 |  |  |
Unrecognized compensation cost, weighted average remaining requisite service period |  |  |  | 3 years 1 month 28 days |  |  |
Number of unvested options and restricted stock units |  |  |  | 1,953,733 |  |  |
Incentive options, term |  |  |  | 10 years |  |  |
2018 Plan |  |  |  |  |  |  |
Stockholders Equity Note Disclosure [Line Items] |  |  |  |  |  |  |
Common stock shares reserved for Issuance |  |  |  |  |  |  | 2,778,000
Incentive options, vesting period |  |  |  | 2,127,217 |  |  |
Employee Stock Option | Minimum |  |  |  |  |  |  |
Stockholders Equity Note Disclosure [Line Items] |  |  |  |  |  |  |
Incentive options, vesting period |  |  |  | 3 years |  |  |
Employee Stock Option | Minimum | Vest Over Three Year |  |  |  |  |  |  |
Stockholders Equity Note Disclosure [Line Items] |  |  |  |  |  |  |
Incentive options, vesting percentage |  |  |  | 20.00% |  |  |
Employee Stock Option | Maximum |  |  |  |  |  |  |
Stockholders Equity Note Disclosure [Line Items] |  |  |  |  |  |  |
Incentive options, vesting period |  |  |  | 5 years |  |  |
Employee Stock Option | Maximum | Vest Over Five Year |  |  |  |  |  |  |
Stockholders Equity Note Disclosure [Line Items] |  |  |  |  |  |  |
Incentive options, vesting percentage |  |  |  | 33.00% |  |  |
Option To Purchase Common Stock |  |  |  |  |  |  |
Stockholders Equity Note Disclosure [Line Items] |  |  |  |  |  |  |
Stock options, outstanding |  |  |  | 625,107 | 696,711 | 957,559 |
Restricted Stock Units (RSUs) |  |  |  |  |  |  |
Stockholders Equity Note Disclosure [Line Items] |  |  |  |  |  |  |
Restricted stock units, outstanding |  |  |  | 606,685 | 665,540 | 734,984 |
Closing price of common stock |  |  |  | $ 264.84 |  |  |
Unvested Options [Member] |  |  |  |  |  |  |
Stockholders Equity Note Disclosure [Line Items] |  |  |  |  |  |  |
Incentive options, vesting period |  |  |  | 5 years |  |  |
Restricted Stock And Performance Stock Units [Member] |  |  |  |  |  |  |
Stockholders Equity Note Disclosure [Line Items] |  |  |  |  |  |  |
Restricted stock units, outstanding |  |  |  | 606,685 |  |  |
Closing price of common stock |  |  |  | $ 264.84 |  |  |
Aggregate intrinsic value of restricted stock units vested |  |  |  | $ 46,500 | $ 28,300 | $ 17,500 |
Weighted average grant date fair value of restricted stock units granted |  |  |  | $ 222.17 | $ 109.69 | $ 67.22 |
Total grant date fair value of restricted stock units vested |  |  |  | $ 13,900 | $ 10,800 | $ 8,500 |
Non Employee Director Stock Option[Member] |  |  |  |  |  |  |
Stockholders Equity Note Disclosure [Line Items] |  |  |  |  |  |  |
Estimated forfeiture rates |  |  |  | 0.00% |  |  |
Incentive options, vesting period |  |  |  | 9 years |  |  |
Underwriters | Common Stock |  |  |  |  |  |  |
Stockholders Equity Note Disclosure [Line Items] |  |  |  |  |  |  |
Exercised number of shares | 225,000 | 207,000 | 410,156 |  |  |  |
Non-Executive [Member] | Employee Stock Option |  |  |  |  |  |  |
Stockholders Equity Note Disclosure [Line Items] |  |  |  |  |  |  |
Estimated forfeiture rates |  |  |  | 8.00% |  |  |
Non-Executive [Member] | Restricted Stock And Performance Stock Units [Member] |  |  |  |  |  |  |
Stockholders Equity Note Disclosure [Line Items] |  |  |  |  |  |  |
Estimated forfeiture rates |  |  |  | 8.00% |  |  |
Executive Officer [Member] | Employee Stock Option |  |  |  |  |  |  |
Stockholders Equity Note Disclosure [Line Items] |  |  |  |  |  |  |
Estimated forfeiture rates |  |  |  | 3.00% |  |  |
Executive Officer [Member] | Restricted Stock And Performance Stock Units [Member] |  |  |  |  |  |  |
Stockholders Equity Note Disclosure [Line Items] |  |  |  |  |  |  |
Estimated forfeiture rates |  |  |  | 3.00% |  |  |

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