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Stock-Based Compensation Expense (Detail) - USD ($) $ in Thousands | 3 Months Ended | 9 Months Ended
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Sep. 30, 2022 | Sep. 30, 2021 | Sep. 30, 2022 | Sep. 30, 2021
Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Line Items] |  |  |  |
Stock-based compensation expense | $ 6,154 | $ 6,792 | $ 21,054 | $ 20,476
Cost of product revenue |  |  |  |
Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Line Items] |  |  |  |
Stock-based compensation expense | 610 | 489 | 1,847 | 1,444
Research and development |  |  |  |
Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Line Items] |  |  |  |
Stock-based compensation expense | 534 | 698 | 1,955 | 2,209
Selling, general and administrative |  |  |  |
Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Line Items] |  |  |  |
Stock-based compensation expense | $ 5,010 | $ 5,605 | $ 17,252 | $ 16,823

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- Definition Amount of noncash expense for share-based payment arrangement. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 28 -Subparagraph (a) -URI https://asc.fasb.org/extlink&oid=126954810&loc=d3e3602-108585 + Details
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