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Income Taxes - Schedule of reconciliation of income tax benefit (Details) - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2021	Dec. 31, 2020	Dec. 31, 2019
Income Tax Disclosure [Abstract]
Income tax benefit computed at federal statutory rate	$ 71,322	$ (48,307)	$ (19,960)
Foreign rate differential	1,214	(1,317)	(144)
Stock-based compensation expense	104,993	24,004	1,612
Change in valuation allowance	192,301	27,446	18,958
Research and development credits	(14,483)	(2,432)	(1,112)
Other	457	399	641
Provision for (benefit from) income taxes	$ 3,174	$ (207)	$ (5)

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Amount of current income tax expense (benefit) and deferred income tax expense (benefit) pertaining to continuing operations.

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Amount of the difference between reported income tax expense (benefit) and expected income tax expense (benefit) computed by applying the domestic federal statutory income tax rates to pretax income (loss) from continuing operations attributable to increase (decrease) in the valuation allowance for deferred tax assets.

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