v3.25.4

Income Taxes - Additional Information (Details) - USD ($) $ in Thousands | 12 Months Ended
--- | ---
Dec. 31, 2025 | Dec. 31, 2024 | Dec. 31, 2023
Operating Loss Carryforwards [Line Items] |  |  |
Valuation allowance | $ 706,349 | $ 671,718 |
Accrued deferred U.S. state income and foreign withholding taxes | 3,300 |  |
Foreign net operating loss carryforwards | 60,500 |  |
Income tax interest and penalties | 0 | $ 0 | $ 0
United Kingdom |  |  |
Operating Loss Carryforwards [Line Items] |  |  |
(Decrease) increase in valuation allowance | (18,000) |  |
United States |  |  |
Operating Loss Carryforwards [Line Items] |  |  |
(Decrease) increase in valuation allowance | 51,800 |  |
Valuation allowance | 706,300 |  |
Federal NOLs carryover | 1,588,800 |  |
Research tax credit carryforwards | 102,600 |  |
State |  |  |
Operating Loss Carryforwards [Line Items] |  |  |
Federal NOLs carryover | 812,600 |  |
Research tax credit carryforwards | $ 45,000 |  |

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