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CONSOLIDATED STATEMENTS OF CASH FLOWS - USD ($)
$ in Thousands
 6 Months Ended
Jun. 30, 2017
Jun. 30, 2016
CASH FLOWS FROM OPERATING ACTIVITIES:    
Net income $ 57,552 $ 23,751
Adjustments to reconcile net income to net cash provided by operating activities:    
Amortization of deferred revenue (4,873) (3,601)
Depreciation 2,398 1,839
Amortization of intangibles 10,987 5,579
Amortization of premium and discount on investments, net (1,260) (801)
Stock-based compensation to employees 5,404 5,401
Stock-based compensation to Board of Directors and Scientific Advisory Board 1,328 891
Change in earnout liability recorded for Adesis acquisition 469  
Deferred income tax expense 7,408 4,826
Retirement plan expense 2,088 1,982
Decrease (increase) in assets:    
Accounts receivable (14,708) 6,745
Inventory (7,123) (3,719)
Other current assets (799) (3,174)
Other assets (10) (369)
Increase (decrease) in liabilities:    
Accounts payable and accrued expenses (1,916) (5,625)
Other current liabilities (821) 256
Deferred revenue 505 2,250
Net cash provided by operating activities 56,629 36,231
CASH FLOWS FROM INVESTING ACTIVITIES:    
Purchases of property and equipment (9,717) (2,162)
Purchases of intangibles   (96,033)
Purchases of investments (255,224) (325,226)
Proceeds from sale of investments 189,335 364,017
Net cash used in investing activities (75,606) (59,404)
CASH FLOWS FROM FINANCING ACTIVITIES:    
Proceeds from issuance of common stock 349 202
Proceeds from the exercise of common stock options 30 182
Payment of withholding taxes related to stock-based compensation to employees (8,501) (4,794)
Cash dividends paid (2,828)  
Net cash used in financing activities (10,950) (4,410)
DECREASE IN CASH AND CASH EQUIVALENTS (29,927) (27,583)
CASH AND CASH EQUIVALENTS, BEGINNING OF PERIOD 139,365 97,513
CASH AND CASH EQUIVALENTS, END OF PERIOD $ 109,438 $ 69,930