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STOCK-BASED COMPENSATION - Equity Instruments Other Than Options - Additional Information (Details) - USD ($)
12 Months Ended
Dec. 31, 2017
Dec. 31, 2016
Dec. 31, 2015
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]      
Compensation expense $ 0 $ 0 $ 0
Fair value of shares withheld for tax withholding obligations $ 9,432,000 $ 4,871,000 $ 5,337,000
Restricted Stock Units (RSUs) [Member]      
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]      
Weighted average grant-date fair value of restricted stock awards and units fully vested (in dollars per share) $ 116.58 $ 53.85 $ 41.09
Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Vested in Period, Fair Value $ 8,300,000 $ 5,400,000 $ 5,600,000
Grants in period (shares) 69,497    
Restricted Stock Units (RSUs) [Member] | Research and Development Expense [Member] | Non Employee Members of Scientific Advisory Board [Member]      
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]      
Compensation expense $ 976,000 $ 242,000 $ 426,000
Restricted Stock [Member]      
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]      
Weighted average grant-date fair value of restricted stock awards and units fully vested (in dollars per share) $ 83.25 $ 65.37 $ 43.49
Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Vested in Period, Fair Value $ 14,800,000 $ 8,600,000 $ 7,300,000
Shares withheld for employee taxes (shares) 89,661 84,135 99,345
Shares withheld for employee taxes $ 7,800,000 $ 4,500,000 $ 4,200,000
Grants in period (shares) 3,604    
Employee Service Share-based Compensation, Nonvested Awards, Compensation Cost Not yet Recognized $ 30,200,000    
Employee Service Share-based Compensation, Nonvested Awards, Compensation Cost Not yet Recognized, Period for Recognition 2 years 5 months 19 days    
Restricted Stock [Member] | Selling, General and Administrative Expense [Member]      
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]      
Compensation expense $ 8,500,000 6,600,000 5,800,000
Restricted Stock [Member] | Manufacturing Expense [Member]      
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]      
Compensation expense 443,000 1,100,000 178,000
Restricted Stock [Member] | Research and Development Expense [Member]      
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]      
Compensation expense $ 1,600,000 $ 1,700,000 $ 1,900,000
Performance Shares [Member]      
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]      
Weighted average grant-date fair value of restricted stock awards and units fully vested (in dollars per share) $ 105.65 $ 58.46 $ 35.98
Shares withheld for employee taxes (shares)   0  
Grants in period (shares) 24,664 25,045  
Shares withheld for tax withholding obligations (in shares) 19,217    
Fair value of shares withheld for tax withholding obligations $ 1,600,000    
Employee Service Share-based Compensation, Nonvested Awards, Compensation Cost Not yet Recognized $ 1,900,000    
Employee Service Share-based Compensation, Nonvested Awards, Compensation Cost Not yet Recognized, Period for Recognition 1 year 8 months 8 days    
Performance Shares [Member] | Performance-Based Vesting Requirement [Member]      
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]      
Grants in period (shares) 7,817 12,520  
Performance Shares [Member] | Market-Based Vesting Requirement [Member]      
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]      
Grants in period (shares) 7,821 12,525  
Performance Shares [Member] | Company Performance-Based Vesting Requirement [Member]      
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]      
Grants in period (shares) 9,026    
Performance Shares [Member] | Selling, General and Administrative Expense [Member]      
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]      
Compensation expense $ 1,200,000 $ 1,300,000 $ 854,000
Performance Shares [Member] | Manufacturing Expense [Member]      
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]      
Compensation expense 119,000 133,000 17,000
Performance Shares [Member] | Research and Development Expense [Member]      
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]      
Compensation expense $ 276,000 $ 356,000 $ 237,000