    <SEC-DOCUMENT>0001104659-19-001165-index.html : 20190108
    <SEC-HEADER>0001104659-19-001165.hdr.sgml : 20190108
    <ACCEPTANCE-DATETIME>20190107191355
    ACCESSION NUMBER:		0001104659-19-001165
    CONFORMED SUBMISSION TYPE:	8-K
    PUBLIC DOCUMENT COUNT:		33
    CONFORMED PERIOD OF REPORT:	20190104
    ITEM INFORMATION:		Regulation FD Disclosure
    ITEM INFORMATION:		Financial Statements and Exhibits
    FILED AS OF DATE:		20190108
    DATE AS OF CHANGE:		20190107

    FILER:

    	COMPANY DATA:
    		COMPANY CONFORMED NAME:			RHYTHM PHARMACEUTICALS, INC.
    		CENTRAL INDEX KEY:			0001649904
    		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
    		IRS NUMBER:				462159271
    		STATE OF INCORPORATION:			DE
    		FISCAL YEAR END:			1231

    	FILING VALUES:
    		FORM TYPE:		8-K
    		SEC ACT:		1934 Act
    		SEC FILE NUMBER:	001-38223
    		FILM NUMBER:		19514360

    	BUSINESS ADDRESS:
    		STREET 1:		500 BOYLSTON STREET
    		STREET 2:		11TH FLOOR
    		CITY:			BOSTON
    		STATE:			MA
    		ZIP:			02116
    		BUSINESS PHONE:		857-264-4280

    	MAIL ADDRESS:
    		STREET 1:		500 BOYLSTON STREET
    		STREET 2:		11TH FLOOR
    		CITY:			BOSTON
    		STATE:			MA
    		ZIP:			02116

    	FORMER COMPANY:
    		FORMER CONFORMED NAME:	RHYTHM METABOLIC, INC.
    		DATE OF NAME CHANGE:	20150803
    </SEC-HEADER>
    <DOCUMENT>
    <TYPE>8-K
    <SEQUENCE>1
    <FILENAME>a19-1257_18k.htm
    <DESCRIPTION>8-K
    <TEXT>
    Document 1 - file: a19-1257_18k.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-99.1
    <SEQUENCE>2
    <FILENAME>a19-1257_1ex99d1.htm
    <DESCRIPTION>EX-99.1
    <TEXT>
    Document 2 - file: a19-1257_1ex99d1.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-99.2
    <SEQUENCE>3
    <FILENAME>a19-1257_1ex99d2.htm
    <DESCRIPTION>EX-99.2
    <TEXT>
    Document 3 - file: a19-1257_1ex99d2.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>4
    <FILENAME>g12571moi001.gif
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 4 - file: g12571moi001.gif

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>5
    <FILENAME>g12571moi002.gif
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 5 - file: g12571moi002.gif

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>6
    <FILENAME>g12571moi003.gif
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 6 - file: g12571moi003.gif

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>7
    <FILENAME>g12571moi004.gif
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 7 - file: g12571moi004.gif

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>8
    <FILENAME>g12571moi005.gif
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 8 - file: g12571moi005.gif

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>9
    <FILENAME>g12571moi006.gif
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 9 - file: g12571moi006.gif

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>10
    <FILENAME>g12571moi007.gif
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 10 - file: g12571moi007.gif

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>11
    <FILENAME>g12571moi008.gif
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 11 - file: g12571moi008.gif

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>12
    <FILENAME>g12571moi009.gif
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 12 - file: g12571moi009.gif

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>13
    <FILENAME>g12571moi010.gif
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 13 - file: g12571moi010.gif

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>14
    <FILENAME>g12571moi011.gif
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 14 - file: g12571moi011.gif

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>15
    <FILENAME>g12571moi012.gif
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 15 - file: g12571moi012.gif

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>16
    <FILENAME>g12571moi013.gif
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 16 - file: g12571moi013.gif

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>17
    <FILENAME>g12571moi014.gif
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 17 - file: g12571moi014.gif

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>18
    <FILENAME>g12571moi015.gif
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 18 - file: g12571moi015.gif

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>19
    <FILENAME>g12571moi016.gif
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 19 - file: g12571moi016.gif

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>20
    <FILENAME>g12571moi017.gif
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 20 - file: g12571moi017.gif

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>21
    <FILENAME>g12571moi018.gif
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 21 - file: g12571moi018.gif

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>22
    <FILENAME>g12571moi019.gif
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 22 - file: g12571moi019.gif

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>23
    <FILENAME>g12571moi020.gif
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 23 - file: g12571moi020.gif

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>24
    <FILENAME>g12571moi021.gif
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 24 - file: g12571moi021.gif

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>25
    <FILENAME>g12571moi022.gif
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 25 - file: g12571moi022.gif

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>26
    <FILENAME>g12571moi023.gif
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 26 - file: g12571moi023.gif

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>27
    <FILENAME>g12571moi024.gif
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 27 - file: g12571moi024.gif

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>28
    <FILENAME>g12571moi025.gif
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 28 - file: g12571moi025.gif

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>29
    <FILENAME>g12571moi026.gif
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 29 - file: g12571moi026.gif

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>30
    <FILENAME>g12571moi027.gif
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 30 - file: g12571moi027.gif

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>31
    <FILENAME>g12571moi028.gif
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 31 - file: g12571moi028.gif

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>32
    <FILENAME>g12571moi029.gif
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 32 - file: g12571moi029.gif

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>33
    <FILENAME>g12571mmi001.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 33 - file: g12571mmi001.jpg

    </DOCUMENT>
    </SEC-DOCUMENT>