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v3.21.1

CONSOLIDATED STATEMENTS OF CASH FLOWS - USD ($) $ in Thousands | 3 Months Ended
--- | ---
Mar. 31, 2021 | Mar. 31, 2020
Operating activities |  |
Net income (loss) | $ 43,750 | $ (34,164)
Adjustments to reconcile net loss to cash used in operating activities: |  |
Stock-based compensation expense | 5,191 | 5,475
Gain on sale of priority review voucher | (100,000) |
Deferred tax provision | 22,006 |
Depreciation and amortization | 201 | 167
Non-cash rent expense | (61) | (56)
Changes in operating assets and liabilities: |  |
Prepaid expenses and other current assets | 1,651 | (847)
Accounts payable, accrued expenses and other current liabilities | (6,269) | (6,673)
Net cash used in operating activities | (33,531) | (36,098)
Investing activities |  |
Purchases of short-term investments | (297,542) | (15,370)
Maturities of short-term investments | 51,842 | 44,243
Proceeds from sale of priority review voucher | 100,000 |
Purchases of property and equipment | (12) |
Net cash (used in) provided by investing activities | (145,712) | 28,873
Financing activities |  |
Net proceeds from issuance of common stock | 161,731 |
Proceeds from the exercise of stock options | 3,466 | 383
Proceeds from issuance of common stock from ESPP | 388 | 324
Net cash provided by financing activities | 165,585 | 707
Net decrease in cash, cash equivalents and restricted cash | (13,658) | (6,518)
Cash, cash equivalents and restricted cash at beginning of period | 101,257 | 62,697
Cash, cash equivalents and restricted cash at end of period | $ 87,599 | $ 56,179

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