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v3.23.3

CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS - USD ($) $ in Thousands | 9 Months Ended
--- | ---
Sep. 30, 2023 | Sep. 30, 2022
Operating activities |  |
Net loss | $ (143,045) | $ (138,626)
Adjustments to reconcile net loss to net cash used in operating activities: |  |
Stock-based compensation expense | 23,879 | 14,544
Depreciation and amortization | 1,341 | 1,230
Non-cash interest expense and amortization of debt issuance costs | 9,342 | 2,190
Non-cash rent expense | 294 | (198)
Loss on RareStone equity investment |  | 1,040
Change in fair value of embedded derivative liability | (150) |
Acquired IPR&D assets classified as investing activities | 5,667 |
Changes in operating assets and liabilities: |  |
Accounts receivable | (8,317) | (2,303)
Inventory | (4,845) | (1,575)
Prepaid expenses and other current assets | (2,367) | 2,806
Deferred revenue | (148) | 474
Other long-term assets | 1,660 | (4,841)
Accounts payable, accrued expenses and other liabilities | 9,915 | (14,169)
Net cash used in operating activities | (106,774) | (139,428)
Investing activities |  |
Purchases of short-term investments, net | (314,265) | (151,521)
Maturities of short-term investments | 291,675 | 224,607
Acquisition of IPR&D assets, including transaction costs | (5,667) |
Payment of milestone obligation under license agreement |  | (4,000)
Purchases of property and equipment | (48) | (282)
Net cash (used in) provided by investing activities | (28,305) | 68,804
Financing activities |  |
Net proceeds from issuance of common stock | 48,875 | 116,974
Proceeds from the exercise of stock options | 2,471 | 3,863
Proceeds from issuance of common stock from ESPP | 1,053 | 626
Repayment of deferred royalty obligation | (4,824) |
Proceeds from royalty financing agreement, net of issuance costs | 24,370 | 75,000
Net cash provided by financing activities | 71,945 | 196,463
Effect of exchange rates on cash | 50 |
Net (decrease) increase in cash, cash equivalents and restricted cash | (63,084) | 125,839
Cash, cash equivalents and restricted cash at beginning of period | 128,005 | 59,576
Cash, cash equivalents and restricted cash at end of period | $ 64,921 | 185,415
Supplemental disclosures: |  |
Deferred financing costs in accrued expenses |  | $ 957

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