EX-21.1 4 rytm-20231231xex21d1.htm EX-21.1

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Exhibit 21.1

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Subsidiaries of Rhythm Pharmaceuticals, Inc.

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Entity |  | Jurisdiction of Organization or Incorporation
Rhythm Pharmaceuticals Limited | ​ | Ireland
Rhythm Securities Corp. |  | Massachusetts
Rhythm Pharmaceuticals Netherlands, B.V. | ​ | The Netherlands
Rhythm Pharmaceuticals UK Limited Rhythm Pharmaceuticals France SAS Rhythm Pharmaceuticals Italy S.r.L. Rhythm Pharmaceuticals Canada Inc. | ​ | United Kingdom France Italy Canada
Rhythm Pharmaceuticals Germany GmbH | ​ | Germany
Xinvento, B.V. |  | The Netherlands
Rhythm Pharmaceuticals Spain S.L. ​ | ​ | Spain ​ ​ ​