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Condensed Consolidated Statements of Cash Flows - USD ($) shares in Thousands, $ in Thousands | 6 Months Ended
--- | ---
Jun. 30, 2024 | Jun. 30, 2023
Operating activities |  |
Net loss | $ (173,633) | $ (98,882)
Adjustments to reconcile net loss to net cash used in operating activities: |  |
Stock-based compensation expense | 18,125 | 15,267
Depreciation and amortization | 795 | 899
Non-cash interest expense | 7,987 | 6,194
Non-cash accretion & amortization of short-term investments | (3,562) | (4,299)
Non-cash accretion of non-current liability | 1,927 |
Non-cash rent expense | 181 | 192
Change in fair value of embedded derivative liability | (790) | (20)
Gain on settlement of forward contract | (8,900) |
Acquired IPR&D assets classified as investing activities | 92,385 | 5,650
Changes in operating assets and liabilities: |  |
Accounts receivable | (2,731) | (7,607)
Inventory | (3,370) | (3,260)
Prepaid expenses and other current assets | 287 | 1,540
Deferred revenue |  | (148)
Other long-term assets, net | 2,249 | 1,123
Accounts payable, accrued expenses and other liabilities | (769) | 5,828
Net cash used in operating activities | (69,819) | (77,523)
Investing activities |  |
Purchases of short-term investments | (66,312) | (145,078)
Maturities of short-term investments | 127,800 | 217,175
Acquisition of IPR&D assets | (40,000) | (5,395)
Purchases of property and equipment |  | (47)
Net cash provided by investing activities | 21,488 | 66,655
Financing activities |  |
Repayment of deferred royalty obligation | (5,756) | (2,657)
Proceeds from the exercise of stock options | 7,755 | 894
Proceeds from issuance of common stock from ESPP | 673 | 665
Gain on settlement of forward contract | 8,900 |
Proceeds from Series A Preferred Stock, net of issuance costs | 138,850 |
Net cash provided by (used in) financing activities | 150,422 | (1,098)
Effect of exchange rates on cash | (372) | (27)
Net increase (decrease) in cash, cash equivalents and restricted cash | 101,719 | (11,993)
Cash, cash equivalents and restricted cash at beginning of period | 60,409 | 128,005
Cash, cash equivalents and restricted cash at end of period | 162,128 | 116,012
Supplemental disclosure of non-cash investing and financing activities: |  |
Non-current liability issued in exchange for the acquisition of IPR&D | $ 33,669 |
Issuance of common stock in exchange for IPR&D | 18,716 |
Accretion of preferred stock dividends | $ 1,302 |
Holdback payable associated with acquisition of IPR&D assets, in accrued expenses |  | 500
Transaction costs associated with acquisition of IPR&D assets, in accounts payable |  | $ 255

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