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Research and Development Arrangements - Additional Information (Detail) - USD ($) $ in Thousands | 3 Months Ended | 12 Months Ended
--- | --- | ---
Mar. 31, 2026 | Mar. 31, 2025 | Dec. 31, 2025 | Dec. 31, 2024
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |
Total revenues | $ 19,355 | $ 1,579 |  |
Accounts receivable | 6,827 |  | $ 17,764 |
Research and development | 95,525 | 98,262 |  |
Corxel Aficamten License and Collaboration Agreement [Member] |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |
Maximum future development and commercial milestone payments achievable | 160,000 |  |  |
Development and commercial milestone received |  |  | 15,000 | $ 10,000
Bayer License Agreement [Member] |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |
Accounts receivable | 2,100 |  | 2,600 |
Sanofi License Agreement [Member] |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |
Accounts receivable | 200 |  | $ 15,100 |
Research Collaboration [Member] |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |
Research and development | 1,200 |  |  |
License and Milestone Revenues [Member] |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |
Total revenues | 11,929 | 0 |  |
License and Milestone Revenues [Member] | Bayer License Agreement [Member] |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |
Total revenues | 11,900 |  |  |
Collaboration Revenues [Member] |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |
Total revenues | 2,637 | 1,579 |  |
Collaboration Revenues [Member] | China [Member] |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |
Total revenues | 500 | 100 |  |
Collaboration Revenues [Member] | Bayer License Agreement [Member] |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |
Total revenues | $ 2,100 | $ 1,400 |  |

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