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Condensed Statements of Operations (Unaudited) - USD ($) shares in Thousands, $ in Thousands | 3 Months Ended | 6 Months Ended
--- | --- | ---
Jun. 30, 2020 | Jun. 30, 2019 | Jun. 30, 2020 | Jun. 30, 2019
Income Statement [Abstract] |  |  |  |
Collaboration revenue | $ 1,541 | $ 224 | $ 2,899 | $ 224
Revenue from Contract with Customer, Product and Service [Extensible List] | rna:CollaborationRevenueMember | rna:CollaborationRevenueMember | rna:CollaborationRevenueMember | rna:CollaborationRevenueMember
Operating expenses: |  |  |  |
Research and development | $ 8,984 | $ 2,533 | $ 14,528 | $ 3,795
General and administrative | 2,925 | 1,596 | 4,889 | 2,508
Total operating expenses | 11,909 | 4,129 | 19,417 | 6,303
Loss from operations | (10,368) | (3,905) | (16,518) | (6,079)
Other income (expense): |  |  |  |
Interest income | 18 | 0 | 161 | 0
Interest and other expense | (131) | (1,215) | (209) | (1,587)
Change in fair value of preferred warrant liability | (75) | 4 | (75) | 1
Total other income (expense) | (188) | (1,211) | (123) | (1,586)
Net loss | $ (10,556) | $ (5,116) | $ (16,641) | $ (7,665)
Net loss per share, basic and diluted | $ (1.23) | $ (1.89) | $ (2.91) | $ (2.87)
Weighted-average shares outstanding, basic and diluted | 8,586 | 2,704 | 5,715 | 2,669

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