<SEC-DOCUMENT>0000929638-21-000369.txt : 20210216
<SEC-HEADER>0000929638-21-000369.hdr.sgml : 20210216
<ACCEPTANCE-DATETIME>20210216151005
ACCESSION NUMBER:		0000929638-21-000369
CONFORMED SUBMISSION TYPE:	SC 13G/A
PUBLIC DOCUMENT COUNT:		1
FILED AS OF DATE:		20210216
DATE AS OF CHANGE:		20210216
GROUP MEMBERS:		BIHUA CHEN
GROUP MEMBERS:		CORMORANT GLOBAL HEALTHCARE GP, LLC
GROUP MEMBERS:		CORMORANT GLOBAL HEALTHCARE MASTER FUND, LP
GROUP MEMBERS:		CORMORANT PRIVATE HEALTHCARE FUND II, LP
GROUP MEMBERS:		CORMORANT PRIVATE HEALTHCARE GP II, LLC

SUBJECT COMPANY:	

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Avidity Biosciences, Inc.
		CENTRAL INDEX KEY:			0001599901
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				461336960
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		SC 13G/A
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	005-91534
		FILM NUMBER:		21636809

	BUSINESS ADDRESS:	
		STREET 1:		10975 N. TORREY PINES RD.,
		STREET 2:		#150
		CITY:			LA JOLLA
		STATE:			CA
		ZIP:			92037
		BUSINESS PHONE:		858-401-7900

	MAIL ADDRESS:	
		STREET 1:		10975 N. TORREY PINES RD.,
		STREET 2:		#150
		CITY:			LA JOLLA
		STATE:			CA
		ZIP:			92037

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	Avidity Biosciences LLC
		DATE OF NAME CHANGE:	20161227

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	Avidity NanoMedicines LLC
		DATE OF NAME CHANGE:	20140211

FILED BY:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Cormorant Asset Management, LP
		CENTRAL INDEX KEY:			0001583977
		IRS NUMBER:				462108927
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		SC 13G/A

	BUSINESS ADDRESS:	
		STREET 1:		200 CLARENDON STREET
		STREET 2:		52ND FLOOR
		CITY:			BOSTON
		STATE:			MA
		ZIP:			02116
		BUSINESS PHONE:		857-702-0388

	MAIL ADDRESS:	
		STREET 1:		200 CLARENDON STREET
		STREET 2:		52ND FLOOR
		CITY:			BOSTON
		STATE:			MA
		ZIP:			02116

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	Cormorant Asset Management, LLC
		DATE OF NAME CHANGE:	20130807
</SEC-HEADER>
<DOCUMENT>
<TYPE>SC 13G/A
<SEQUENCE>1
<FILENAME>schedule13g.htm
<TEXT>
<html>
  <head>
    <title></title>
    <!-- Licensed to: morganlewis
         Document created using EDGARfilings PROfile 7.3.1.0
         Copyright 1995 - 2021 Broadridge -->
  </head>
<body style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; text-align: left; color: #000000;" bgcolor="#ffffff">
  <table style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%; border-collapse: collapse; text-align: left; color: #000000;" id="zf5a72859d80d41be8eb5ed778633602b" border="0" cellpadding="0" cellspacing="0">

      <tr>
        <td style="width: 20%; vertical-align: top;">&#160;</td>
        <td style="width: 60%; vertical-align: top;">
          <div style="text-align: center; font-family: 'Times New Roman'; font-weight: bold;">UNITED STATES</div>
          <div style="text-align: center; font-family: 'Times New Roman'; font-weight: bold;">SECURITIES AND EXCHANGE COMMISSION</div>
          <div style="text-align: center; font-family: 'Times New Roman'; font-weight: bold;">Washington, D.C. 20549</div>
        </td>
        <td style="width: 20%; vertical-align: top;">&#160;</td>
      </tr>

  </table>
  <div><br>
  </div>
  <table style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%; border-collapse: collapse; text-align: left; color: #000000;" id="zb91b104b831d468084cb518eca77eb7b" border="0" cellpadding="0" cellspacing="0">

      <tr>
        <td style="width: 20%; vertical-align: top;">&#160;</td>
        <td style="width: 60%; vertical-align: top;">
          <div style="text-align: center; font-family: 'Times New Roman'; font-size: 14pt; font-weight: bold;">SCHEDULE 13G</div>
          <div>&#160;</div>
        </td>
        <td style="width: 20%; vertical-align: top;">&#160;</td>
      </tr>
      <tr>
        <td style="width: 20%; vertical-align: top;">&#160;</td>
        <td style="width: 60%; vertical-align: top;">
          <div style="text-align: center; font-family: 'Times New Roman'; font-weight: bold;">Under the Securities Exchange Act of 1934</div>
          <div>&#160;</div>
        </td>
        <td style="width: 20%; vertical-align: top;">&#160;</td>
      </tr>
      <tr>
        <td style="width: 20%; vertical-align: top;">&#160;</td>
        <td style="width: 60%; vertical-align: top;">
          <div style="text-align: center; font-family: 'Times New Roman';"><font style="font-weight: bold;">(Amendment No. 1)</font>*</div>
        </td>
        <td style="width: 20%; vertical-align: top;">&#160;</td>
      </tr>

  </table>
  <div><br>
  </div>
  <table style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%; border-collapse: collapse; text-align: left; color: #000000;" id="zf9c39ffdecc3451caf954ef2c0c5f8ec" cellpadding="0" cellspacing="0">

      <tr>
        <td style="width: 20%; vertical-align: top; border-bottom: 1px solid rgb(0, 0, 0);">&#160;</td>
        <td style="width: 60%; vertical-align: top; border-bottom: 1px solid rgb(0, 0, 0);">
          <div style="text-align: center; font-family: 'Times New Roman'; font-weight: bold;">Avidity Biosciences, Inc.</div>
        </td>
        <td style="width: 20%; vertical-align: top; border-bottom: 1px solid rgb(0, 0, 0);">&#160;</td>
      </tr>
      <tr>
        <td style="width: 20%; vertical-align: top; border-top: 1px solid rgb(0, 0, 0);">&#160;</td>
        <td style="width: 60%; vertical-align: top; border-top: 1px solid rgb(0, 0, 0);">
          <div style="text-align: center; font-family: 'Times New Roman';">(Name of Issuer)</div>
        </td>
        <td style="width: 20%; vertical-align: top; border-top: 1px solid rgb(0, 0, 0);">&#160;</td>
      </tr>

  </table>
  <div><br>
  </div>
  <table style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%; border-collapse: collapse; text-align: left; color: #000000;" id="z04a80b6499194a31ac3d2979a25c01ac" cellpadding="0" cellspacing="0">

      <tr>
        <td style="width: 20%; vertical-align: top; border-bottom: 1px solid rgb(0, 0, 0);">&#160;</td>
        <td style="width: 60%; vertical-align: top; border-bottom: 1px solid rgb(0, 0, 0);">
          <div style="text-align: center; font-family: 'Times New Roman'; font-weight: bold;">Common Stock</div>
        </td>
        <td style="width: 20%; vertical-align: top; border-bottom: 1px solid rgb(0, 0, 0);">&#160;</td>
      </tr>
      <tr>
        <td style="width: 20%; vertical-align: top; border-top: 1px solid rgb(0, 0, 0);">&#160;</td>
        <td style="width: 60%; vertical-align: top; border-top: 1px solid rgb(0, 0, 0);">
          <div style="text-align: center; font-family: 'Times New Roman';">(Title of Class of Securities)</div>
        </td>
        <td style="width: 20%; vertical-align: top; border-top: 1px solid rgb(0, 0, 0);">&#160;</td>
      </tr>

  </table>
  <div><br>
  </div>
  <table style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%; border-collapse: collapse; text-align: left; color: #000000;" id="z9538710cb4b5447eb5b9690774203ad1" cellpadding="0" cellspacing="0">

      <tr>
        <td style="width: 20%; vertical-align: top;">&#160;</td>
        <td style="width: 60%; vertical-align: top; border-bottom: 1px solid rgb(0, 0, 0);">
          <div style="text-align: center; font-family: 'Times New Roman';">05370A108</div>
        </td>
        <td style="width: 20%; vertical-align: top;">&#160;</td>
      </tr>
      <tr>
        <td style="width: 20%; vertical-align: top;">&#160;</td>
        <td style="width: 60%; vertical-align: top; border-top: 1px solid rgb(0, 0, 0);">
          <div style="text-align: center; font-family: 'Times New Roman';">(CUSIP Number)</div>
        </td>
        <td style="width: 20%; vertical-align: top;">&#160;</td>
      </tr>

  </table>
  <div><br>
  </div>
  <table style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%; border-collapse: collapse; text-align: left; color: #000000;" id="z5a69ff073c4649e5b9821366b7fd4a95" cellpadding="0" cellspacing="0">

      <tr>
        <td style="width: 20%; vertical-align: top; border-bottom: 1px solid rgb(0, 0, 0);">&#160;</td>
        <td style="width: 60%; vertical-align: top; border-bottom: 1px solid rgb(0, 0, 0);">
          <div style="text-align: center; font-family: 'Times New Roman'; font-weight: bold;">December 31, 2020<br>
          </div>
        </td>
        <td style="width: 20%; vertical-align: top; border-bottom: 1px solid rgb(0, 0, 0);">&#160;</td>
      </tr>
      <tr>
        <td style="width: 20%; vertical-align: top; border-top: 1px solid rgb(0, 0, 0);">&#160;</td>
        <td style="width: 60%; vertical-align: top; border-top: 1px solid rgb(0, 0, 0);">
          <div style="text-align: center; font-family: 'Times New Roman';">(Date of Event which Requires Filing of this Statement)</div>
        </td>
        <td style="width: 20%; vertical-align: top; border-top: 1px solid rgb(0, 0, 0);">&#160;</td>
      </tr>

  </table>
  <div><br>
  </div>
  <div><br>
  </div>
  <div style="margin-right: 9.35pt; margin-bottom: 12pt; font-family: 'Times New Roman';">Check the appropriate box to designate the rule pursuant to which this Schedule is filed:</div>
  <div style="margin-right: 9.35pt; margin-bottom: 12pt;"><font style="font-family: 'Times New Roman';">[ ]</font><font style="text-indent: 0px; font-size: 5.14pt;" id="TRGRRTFtoHTMLTab">&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;</font><font style="font-family: 'Times New Roman';">Rule
      13d-1(b)</font></div>
  <div style="margin-right: 9.35pt; margin-bottom: 12pt;"><font style="font-family: 'Times New Roman';">[x]</font><font style="text-indent: 0px; font-size: 5.14pt;" id="TRGRRTFtoHTMLTab">&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;</font><font style="font-family: 'Times New Roman';">Rule
      13d-1(c)</font></div>
  <div style="margin-right: 9.35pt; margin-bottom: 96pt;"><font style="font-family: 'Times New Roman';">[ ]</font><font style="text-indent: 0px; font-size: 5.14pt;" id="TRGRRTFtoHTMLTab">&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;</font><font style="font-family: 'Times New Roman';">Rule
      13d-1(d)</font></div>
  <div style="font-family: 'Times New Roman';">___________________________________</div>
  <div style="text-indent: 36pt; margin-bottom: 6pt; font-family: 'Times New Roman';">*&#160; The remainder of this cover page shall be filled out for a reporting person&#8217;s initial filing on this form with respect to the subject class of securities, and for any
    subsequent amendment containing information which would alter the disclosures provided in a prior cover page.</div>
  <div style="text-indent: 45pt; margin-bottom: 6pt; font-family: 'Times New Roman';">The information required in the remainder of this cover page shall not be deemed to be &#8220;filed&#8221; for the purpose of Section&#160;18 of the Securities Exchange Act of 1934
    (&#8220;Act&#8221;) or otherwise subject to the liabilities of that section of the Act but shall be subject to all other provisions of the Act (however, <font style="font-style: italic;">see</font> the Notes).</div>
  <div><br>
  </div>
  <div style="clear: both; margin-top: 10pt; margin-bottom: 10pt;" id="DSPFPageBreakArea">
    <div style="page-break-after:always;" id="DSPFPageBreak">
      <hr style="margin: 4px 0px; width: 100%; border-width: 0; height: 2px; color: #000000; background-color: #000000; clear: both;" noshade="noshade"></div>
  </div>
  <table style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%; border-collapse: collapse; text-align: left; color: #000000;" id="z33e17440d7f946ee97e98c4060792762" cellpadding="0" cellspacing="0">

      <tr>
        <td style="width: 6.82%; vertical-align: top; border-top: #000000 1px solid; border-bottom: #000000 1px solid;">
          <div>&#160;</div>
          <div style="margin-top: 3pt; font-family: 'Times New Roman';">1</div>
        </td>
        <td style="width: 93.18%; vertical-align: top; border-top: #000000 1px solid; border-bottom: #000000 1px solid;">
          <div>&#160;</div>
          <div style="margin-top: 3pt; font-family: 'Times New Roman';">Names of Reporting Persons.</div>
          <div style="margin-top: 3pt; font-family: 'Times New Roman';">I.R.S. Identification Nos. of above persons (entities only)</div>
          <div style="margin-top: 12pt; margin-bottom: 12pt; font-family: 'Times New Roman';">Cormorant Global Healthcare Master Fund, LP</div>
          <div>&#160;</div>
        </td>
      </tr>
      <tr>
        <td style="width: 6.82%; vertical-align: top; border-top: #000000 1px solid;">
          <div>&#160;</div>
          <div style="margin-top: 3pt; font-family: 'Times New Roman';">2</div>
        </td>
        <td style="width: 93.18%; vertical-align: top; border-top: #000000 1px solid;">
          <div>&#160;</div>
          <div style="margin-top: 3pt; font-family: 'Times New Roman';">Check the Appropriate Box if a Member of a Group (See Instructions)</div>
        </td>
      </tr>
      <tr>
        <td style="width: 6.82%; vertical-align: top;">&#160;</td>
        <td style="width: 93.18%; vertical-align: top;">
          <div>&#160;</div>
          <div style="margin-top: 3pt;"><font style="font-family: 'Times New Roman';">(a)</font><font style="text-indent: 0px; font-size: 5.14pt;" id="TRGRRTFtoHTMLTab">&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;</font><font style="font-family: 'Times New Roman';">[ ]</font></div>
        </td>
      </tr>
      <tr>
        <td style="width: 6.82%; vertical-align: top; border-bottom: #000000 1px solid;">&#160;</td>
        <td style="width: 93.18%; vertical-align: top; border-bottom: #000000 1px solid;">
          <div>&#160;</div>
          <div style="margin-top: 3pt;"><font style="font-family: 'Times New Roman';">(b)</font><font style="text-indent: 0px; font-size: 5.14pt;" id="TRGRRTFtoHTMLTab">&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;</font><font style="font-family: 'Times New Roman';">[x]</font></div>
        </td>
      </tr>
      <tr>
        <td style="width: 6.82%; vertical-align: top; border-top: #000000 1px solid; border-bottom: #000000 1px solid;">
          <div>&#160;</div>
          <div style="margin-top: 3pt; font-family: 'Times New Roman';">3</div>
        </td>
        <td style="width: 93.18%; vertical-align: top; border-top: #000000 1px solid; border-bottom: #000000 1px solid;">
          <div>&#160;</div>
          <div style="margin-top: 3pt; font-family: 'Times New Roman';">SEC Use Only</div>
        </td>
      </tr>
      <tr>
        <td style="width: 6.82%; vertical-align: top; border-top: #000000 1px solid; border-bottom: #000000 1px solid;">
          <div>&#160;</div>
          <div style="margin-top: 3pt; font-family: 'Times New Roman';">4</div>
        </td>
        <td style="width: 93.18%; vertical-align: top; border-top: #000000 1px solid; border-bottom: #000000 1px solid;">
          <div>&#160;</div>
          <div style="margin-top: 3pt; font-family: 'Times New Roman';">Citizenship or Place of Organization.</div>
          <div>&#160;</div>
          <div style="margin-bottom: 6pt; font-family: 'Times New Roman';">Cayman Islands</div>
          <div>&#160;</div>
        </td>
      </tr>

  </table>
  <div><br>
  </div>
  <table style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%; border-collapse: collapse; text-align: left; color: #000000;" cellpadding="0" cellspacing="0">

      <tr>
        <td rowspan="4" style="width: 17.69%; vertical-align: middle; border-top: #000000 1px solid; border-bottom: #000000 1px solid;">
          <div>&#160;</div>
          <div style="text-align: center; margin-top: 3pt; font-family: 'Times New Roman';">Number</div>
          <div style="text-align: center; margin-top: 3pt; font-family: 'Times New Roman';">of Shares</div>
          <div style="text-align: center; margin-top: 3pt; font-family: 'Times New Roman';">Beneficially</div>
          <div style="text-align: center; margin-top: 3pt; font-family: 'Times New Roman';">Owned by</div>
          <div style="text-align: center; margin-top: 3pt; font-family: 'Times New Roman';">Each</div>
          <div style="text-align: center; margin-top: 3pt; font-family: 'Times New Roman';">Reporting</div>
          <div style="text-align: center; margin-top: 3pt; font-family: 'Times New Roman';">Person With</div>
        </td>
        <td style="width: 82.31%; vertical-align: middle; border-top: #000000 1px solid; border-bottom: #000000 1px solid;">
          <div>&#160;</div>
          <div style="margin-top: 3pt;"><font style="font-family: 'Times New Roman';">5</font><font style="text-indent: 0px; font-size: 6pt;" id="TRGRRTFtoHTMLTab">&#160;&#160;</font><font style="font-family: 'Times New Roman';">Sole Voting Power</font></div>
          <div>&#160;</div>
          <div style="margin-bottom: 6pt; font-family: 'Times New Roman';">0 shares</div>
          <div>&#160;</div>
        </td>
      </tr>
      <tr>
        <td style="width: 93.05%; vertical-align: middle; border-top: #000000 1px solid; border-bottom: #000000 1px solid;">
          <div>&#160;</div>
          <div style="margin-top: 3pt;"><font style="font-family: 'Times New Roman';">6</font><font style="text-indent: 0px; font-size: 6pt;" id="TRGRRTFtoHTMLTab">&#160;&#160;</font><font style="font-family: 'Times New Roman';">Shared Voting Power</font></div>
          <div>&#160;</div>
          <div style="font-family: 'Times New Roman';">656,553 shares</div>
          <div>&#160;</div>
          <div style="margin-left: 12pt; margin-top: 3pt; font-family: 'Times New Roman';">Refer to Item 4 below.</div>
        </td>
      </tr>
      <tr>
        <td style="width: 93.05%; vertical-align: middle; border-top: #000000 1px solid; border-bottom: #000000 1px solid;">
          <div>&#160;</div>
          <div style="margin-top: 3pt;"><font style="font-family: 'Times New Roman';">7</font><font style="text-indent: 0px; font-size: 6pt;" id="TRGRRTFtoHTMLTab">&#160;&#160;</font><font style="font-family: 'Times New Roman';">Sole Dispositive Power</font></div>
          <div>&#160;</div>
          <div style="margin-bottom: 6pt; font-family: 'Times New Roman';">0 shares</div>
          <div>&#160;</div>
        </td>
      </tr>
      <tr>
        <td style="width: 93.05%; vertical-align: middle; border-top: #000000 1px solid; border-bottom: #000000 1px solid;">
          <div>&#160;</div>
          <div style="margin-top: 3pt;"><font style="font-family: 'Times New Roman';">8</font><font style="text-indent: 0px; font-size: 6pt;" id="TRGRRTFtoHTMLTab">&#160;&#160;</font><font style="font-family: 'Times New Roman';">Shared Dispositive Power</font></div>
          <div>&#160;</div>
          <div style="margin-bottom: 6pt; font-family: 'Times New Roman';">656,553 shares</div>
          <div style="margin-left: 12pt; margin-top: 3pt; font-family: 'Times New Roman';">Refer to Item 4 below.</div>
        </td>
      </tr>

  </table>
  <div><br>
  </div>
  <table style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%; border-collapse: collapse; text-align: left; color: #000000;" cellpadding="0" cellspacing="0">

      <tr>
        <td style="width: 6.82%; vertical-align: top; border-top: #000000 1px solid; border-bottom: #000000 1px solid;">
          <div>&#160;</div>
          <div style="margin-top: 3pt; font-family: 'Times New Roman';">9</div>
        </td>
        <td style="width: 93.05%; vertical-align: top; border-top: #000000 1px solid; border-bottom: #000000 1px solid;">
          <div>&#160;</div>
          <div style="margin-top: 3pt; font-family: 'Times New Roman';">Aggregate Amount Beneficially Owned by Each Reporting Person</div>
          <div>&#160;</div>
          <div style="font-family: 'Times New Roman';">656,553 shares</div>
          <div style="margin-top: 6pt; font-family: 'Times New Roman';">Refer to Item 4 below.</div>
        </td>
        <td style="width: 0.13%; vertical-align: top;">&#160;</td>
      </tr>
      <tr>
        <td style="width: 6.82%; vertical-align: top; border-top: #000000 1px solid; border-bottom: #000000 1px solid;">
          <div>&#160;</div>
          <div style="margin-top: 3pt; font-family: 'Times New Roman';">10</div>
        </td>
        <td style="width: 93.05%; vertical-align: top; border-top: #000000 1px solid; border-bottom: #000000 1px solid;">
          <div>&#160;</div>
          <div style="text-align: justify; margin-top: 3pt; font-family: 'Times New Roman';">Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions)</div>
          <div style="text-align: justify; margin-top: 3pt; font-family: 'Times New Roman';">&#160;&#160;&#160;&#160;[ ] <font style="color: #000000;">N/A</font></div>
        </td>
        <td style="width: 0.13%; vertical-align: top;">&#160;</td>
      </tr>
      <tr>
        <td style="width: 6.82%; vertical-align: top; border-top: #000000 1px solid; border-bottom: #000000 1px solid;">
          <div>&#160;</div>
          <div style="margin-top: 3pt; font-family: 'Times New Roman';">11</div>
        </td>
        <td style="width: 93.05%; vertical-align: top; border-top: #000000 1px solid; border-bottom: #000000 1px solid;">
          <div>&#160;</div>
          <div style="margin-top: 3pt; font-family: 'Times New Roman';">Percent of Class Represented by Amount in Row (9)*</div>
          <div>&#160;</div>
          <div style="font-family: 'Times New Roman';">1.75%</div>
          <div style="margin-top: 6pt; font-family: 'Times New Roman';">Refer to Item 4 below.</div>
        </td>
        <td style="width: 0.13%; vertical-align: top;">&#160;</td>
      </tr>
      <tr>
        <td style="width: 6.82%; vertical-align: top; border-top: #000000 1px solid; border-bottom: #000000 1px solid;">
          <div>&#160;</div>
          <div style="margin-top: 3pt; font-family: 'Times New Roman';">12</div>
        </td>
        <td style="width: 93.05%; vertical-align: top; border-top: #000000 1px solid; border-bottom: #000000 1px solid;">
          <div>&#160;</div>
          <div style="margin-top: 3pt; font-family: 'Times New Roman';">Type of Reporting Person (See Instructions)</div>
          <div style="margin-top: 12pt; font-family: 'Times New Roman';">PN (Partnership)</div>
        </td>
        <td style="width: 0.13%; vertical-align: top;">&#160;</td>
      </tr>

  </table>
  <div><br>
  </div>
  <div style="clear: both; margin-top: 10pt; margin-bottom: 10pt;" id="DSPFPageBreakArea">
    <div style="page-break-after:always;" id="DSPFPageBreak">
      <hr style="margin: 4px 0px; width: 100%; border-width: 0; height: 2px; color: #000000; background-color: #000000; clear: both;" noshade="noshade"></div>
  </div>
  <table style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%; border-collapse: collapse; text-align: left; color: #000000;" id="z19a5aa23a82746528f243b11c01296ad" cellpadding="0" cellspacing="0">

      <tr>
        <td style="width: 6.82%; vertical-align: top; border-top: #000000 1px solid; border-bottom: #000000 1px solid;">
          <div>&#160;</div>
          <div style="margin-top: 3pt; font-family: 'Times New Roman';">1</div>
        </td>
        <td style="width: 93.18%; vertical-align: top; border-top: #000000 1px solid; border-bottom: #000000 1px solid;">
          <div>&#160;</div>
          <div style="margin-top: 3pt; font-family: 'Times New Roman';">Names of Reporting Persons.</div>
          <div style="margin-top: 3pt; font-family: 'Times New Roman';">I.R.S. Identification Nos. of above persons (entities only)</div>
          <div>&#160;</div>
          <div style="font-family: 'Times New Roman';">Cormorant Global Healthcare GP, LLC</div>
          <div>&#160;</div>
        </td>
      </tr>
      <tr>
        <td style="width: 6.82%; vertical-align: top; border-top: #000000 1px solid;">
          <div>&#160;</div>
          <div style="margin-top: 3pt; font-family: 'Times New Roman';">2</div>
        </td>
        <td style="width: 93.18%; vertical-align: top; border-top: #000000 1px solid;">
          <div>&#160;</div>
          <div style="margin-top: 3pt; font-family: 'Times New Roman';">Check the Appropriate Box if a Member of a Group (See Instructions)</div>
        </td>
      </tr>
      <tr>
        <td style="width: 6.82%; vertical-align: top;">&#160;</td>
        <td style="width: 93.18%; vertical-align: top;">
          <div>&#160;</div>
          <div style="margin-top: 3pt;"><font style="font-family: 'Times New Roman';">(a)</font><font style="text-indent: 0px; font-size: 5.14pt;" id="TRGRRTFtoHTMLTab">&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;</font><font style="font-family: 'Times New Roman';">[ ]</font></div>
        </td>
      </tr>
      <tr>
        <td style="width: 6.82%; vertical-align: top; border-bottom: #000000 1px solid;">&#160;</td>
        <td style="width: 93.18%; vertical-align: top; border-bottom: #000000 1px solid;">
          <div>&#160;</div>
          <div style="margin-top: 3pt;"><font style="font-family: 'Times New Roman';">(b)</font><font style="text-indent: 0px; font-size: 5.14pt;" id="TRGRRTFtoHTMLTab">&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;</font><font style="font-family: 'Times New Roman';">[x]</font></div>
        </td>
      </tr>
      <tr>
        <td style="width: 6.82%; vertical-align: top; border-top: #000000 1px solid; border-bottom: #000000 1px solid;">
          <div>&#160;</div>
          <div style="margin-top: 3pt; font-family: 'Times New Roman';">3</div>
        </td>
        <td style="width: 93.18%; vertical-align: top; border-top: #000000 1px solid; border-bottom: #000000 1px solid;">
          <div>&#160;</div>
          <div style="margin-top: 3pt; font-family: 'Times New Roman';">SEC Use Only</div>
        </td>
      </tr>
      <tr>
        <td style="width: 6.82%; vertical-align: top; border-top: #000000 1px solid; border-bottom: #000000 1px solid;">
          <div>&#160;</div>
          <div style="margin-top: 3pt; font-family: 'Times New Roman';">4</div>
        </td>
        <td style="width: 93.18%; vertical-align: top; border-top: #000000 1px solid; border-bottom: #000000 1px solid;">
          <div>&#160;</div>
          <div style="margin-top: 3pt; font-family: 'Times New Roman';">Citizenship or Place of Organization.</div>
          <div>&#160;</div>
          <div style="margin-bottom: 6pt; font-family: 'Times New Roman';">Delaware</div>
          <div>&#160;</div>
        </td>
      </tr>

  </table>
  <div><br>
  </div>
  <table style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%; border-collapse: collapse; text-align: left; color: #000000;" cellpadding="0" cellspacing="0">

      <tr>
        <td rowspan="4" style="width: 17.69%; vertical-align: middle; border-top: #000000 1px solid; border-bottom: #000000 1px solid;">
          <div>&#160;</div>
          <div style="text-align: center; margin-top: 3pt; font-family: 'Times New Roman';">Number</div>
          <div style="text-align: center; margin-top: 3pt; font-family: 'Times New Roman';">of Shares</div>
          <div style="text-align: center; margin-top: 3pt; font-family: 'Times New Roman';">Beneficially</div>
          <div style="text-align: center; margin-top: 3pt; font-family: 'Times New Roman';">Owned by</div>
          <div style="text-align: center; margin-top: 3pt; font-family: 'Times New Roman';">Each</div>
          <div style="text-align: center; margin-top: 3pt; font-family: 'Times New Roman';">Reporting</div>
          <div style="text-align: center; margin-top: 3pt; font-family: 'Times New Roman';">Person With</div>
        </td>
        <td style="width: 82.31%; vertical-align: middle; border-top: #000000 1px solid; border-bottom: #000000 1px solid;">
          <div>&#160;</div>
          <div style="margin-top: 3pt;"><font style="font-family: 'Times New Roman';">5</font><font style="text-indent: 0px; font-size: 6pt;" id="TRGRRTFtoHTMLTab">&#160;&#160;</font><font style="font-family: 'Times New Roman';">Sole Voting Power</font></div>
          <div>&#160;</div>
          <div style="margin-bottom: 6pt; font-family: 'Times New Roman';">0 shares</div>
          <div>&#160;</div>
        </td>
      </tr>
      <tr>
        <td style="width: 93.05%; vertical-align: middle; border-top: #000000 1px solid; border-bottom: #000000 1px solid;">
          <div>&#160;</div>
          <div style="margin-top: 3pt;"><font style="font-family: 'Times New Roman';">6</font><font style="text-indent: 0px; font-size: 6pt;" id="TRGRRTFtoHTMLTab">&#160;&#160;</font><font style="font-family: 'Times New Roman';">Shared Voting Power</font></div>
          <div>&#160;</div>
          <div style="font-family: 'Times New Roman';">656,553 shares</div>
          <div><font style="font-family: 'Times New Roman';"> </font>&#160;</div>
          <div style="margin-left: 12pt; margin-top: 3pt; font-family: 'Times New Roman';">Refer to Item 4 below.</div>
        </td>
      </tr>
      <tr>
        <td style="width: 93.05%; vertical-align: middle; border-top: #000000 1px solid; border-bottom: #000000 1px solid;">
          <div>&#160;</div>
          <div style="margin-top: 3pt;"><font style="font-family: 'Times New Roman';">7</font><font style="text-indent: 0px; font-size: 6pt;" id="TRGRRTFtoHTMLTab">&#160;&#160;</font><font style="font-family: 'Times New Roman';">Sole Dispositive Power</font></div>
          <div>&#160;</div>
          <div style="margin-bottom: 6pt; font-family: 'Times New Roman';">0 shares</div>
          <div>&#160;</div>
        </td>
      </tr>
      <tr>
        <td style="width: 93.05%; vertical-align: middle; border-top: #000000 1px solid; border-bottom: #000000 1px solid;">
          <div>&#160;</div>
          <div style="margin-top: 3pt;"><font style="font-family: 'Times New Roman';">8</font><font style="text-indent: 0px; font-size: 6pt;" id="TRGRRTFtoHTMLTab">&#160;&#160;</font><font style="font-family: 'Times New Roman';">Shared Dispositive Power</font></div>
          <div>&#160;</div>
          <div style="font-family: 'Times New Roman';">656,553 shares</div>
          <div style="margin-left: 12pt; margin-top: 6pt; font-family: 'Times New Roman';">Refer to Item 4 below.</div>
        </td>
      </tr>

  </table>
  <div><br>
  </div>
  <table style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%; border-collapse: collapse; text-align: left; color: #000000;" cellpadding="0" cellspacing="0">

      <tr>
        <td style="width: 6.82%; vertical-align: top; border-top: #000000 1px solid; border-bottom: #000000 1px solid;">
          <div>&#160;</div>
          <div style="margin-top: 3pt; font-family: 'Times New Roman';">9</div>
        </td>
        <td style="width: 93.05%; vertical-align: top; border-top: #000000 1px solid; border-bottom: #000000 1px solid;">
          <div>&#160;</div>
          <div style="margin-top: 3pt; font-family: 'Times New Roman';">Aggregate Amount Beneficially Owned by Each Reporting Person</div>
          <div>&#160;</div>
          <div style="margin-bottom: 6pt; font-family: 'Times New Roman';">656,553 shares</div>
          <div style="margin-top: 3pt; font-family: 'Times New Roman';">Refer to Item 4 below.</div>
        </td>
        <td style="width: 0.13%; vertical-align: top;">&#160;</td>
      </tr>
      <tr>
        <td style="width: 6.82%; vertical-align: top; border-top: #000000 1px solid; border-bottom: #000000 1px solid;">
          <div>&#160;</div>
          <div style="margin-top: 3pt; font-family: 'Times New Roman';">10</div>
        </td>
        <td style="width: 93.05%; vertical-align: top; border-top: #000000 1px solid; border-bottom: #000000 1px solid;">
          <div>&#160;</div>
          <div style="text-align: justify; margin-top: 3pt; font-family: 'Times New Roman';">Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions)</div>
          <div style="text-align: justify; margin-top: 3pt; font-family: 'Times New Roman';">&#160;&#160;&#160;&#160;[ ] <font style="color: #000000;">N/A</font></div>
        </td>
        <td style="width: 0.13%; vertical-align: top;">&#160;</td>
      </tr>
      <tr>
        <td style="width: 6.82%; vertical-align: top; border-top: #000000 1px solid; border-bottom: #000000 1px solid;">
          <div>&#160;</div>
          <div style="margin-top: 3pt; font-family: 'Times New Roman';">11</div>
        </td>
        <td style="width: 93.05%; vertical-align: top; border-top: #000000 1px solid; border-bottom: #000000 1px solid;">
          <div>&#160;</div>
          <div style="margin-top: 3pt; font-family: 'Times New Roman';">Percent of Class Represented by Amount in Row (9)*</div>
          <div>&#160;</div>
          <div style="margin-bottom: 6pt; font-family: 'Times New Roman';">1.75%</div>
          <div style="margin-top: 3pt; font-family: 'Times New Roman';">Refer to Item 4 below.</div>
        </td>
        <td style="width: 0.13%; vertical-align: top;">&#160;</td>
      </tr>
      <tr>
        <td style="width: 6.82%; vertical-align: top; border-top: #000000 1px solid; border-bottom: #000000 1px solid;">
          <div>&#160;</div>
          <div style="margin-top: 3pt; font-family: 'Times New Roman';">12</div>
        </td>
        <td style="width: 93.05%; vertical-align: top; border-top: #000000 1px solid; border-bottom: #000000 1px solid;">
          <div>&#160;</div>
          <div style="margin-top: 3pt; font-family: 'Times New Roman';">Type of Reporting Person (See Instructions)</div>
          <div style="margin-top: 3pt; margin-bottom: 3pt;">&#160;</div>
          <div style="margin-bottom: 6pt; font-family: 'Times New Roman';">OO (Limited Liability Company)</div>
          <div>&#160;</div>
        </td>
        <td style="width: 0.13%; vertical-align: top;">&#160;</td>
      </tr>

  </table>
  <div><br>
  </div>
  <div id="DSPFPageBreakArea" style="clear: both; margin-top: 10pt; margin-bottom: 10pt;">
    <div id="DSPFPageBreak" style="page-break-after: always;">
      <hr style="border-width: 0px; clear: both; margin: 4px 0px; width: 100%; height: 2px; color: #000000; background-color: #000000;" noshade="noshade"></div>
  </div>
  <table style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%; border-collapse: collapse; text-align: left; color: #000000;" cellpadding="0" cellspacing="0">

      <tr>
        <td style="width: 6.82%; vertical-align: top; border-top: #000000 1px solid; border-bottom: #000000 1px solid;">
          <div>&#160;</div>
          <div style="margin-top: 3pt; font-family: 'Times New Roman';">1</div>
        </td>
        <td style="width: 93.18%; vertical-align: top; border-top: #000000 1px solid; border-bottom: #000000 1px solid;">
          <div>&#160;</div>
          <div style="margin-top: 3pt; font-family: 'Times New Roman';">Names of Reporting Persons.</div>
          <div style="margin-top: 3pt; font-family: 'Times New Roman';">I.R.S. Identification Nos. of above persons (entities only)</div>
          <div style="margin-top: 12pt; margin-bottom: 12pt; font-family: 'Times New Roman';">Cormorant Private Healthcare Fund II, LP</div>
          <div>&#160;</div>
        </td>
      </tr>
      <tr>
        <td style="width: 6.82%; vertical-align: top; border-top: #000000 1px solid;">
          <div>&#160;</div>
          <div style="margin-top: 3pt; font-family: 'Times New Roman';">2</div>
        </td>
        <td style="width: 93.18%; vertical-align: top; border-top: #000000 1px solid;">
          <div>&#160;</div>
          <div style="margin-top: 3pt; font-family: 'Times New Roman';">Check the Appropriate Box if a Member of a Group (See Instructions)</div>
        </td>
      </tr>
      <tr>
        <td style="width: 6.82%; vertical-align: top;">&#160;</td>
        <td style="width: 93.18%; vertical-align: top;">
          <div>&#160;</div>
          <div style="margin-top: 3pt;"><font style="font-family: 'Times New Roman';">(a)</font><font style="text-indent: 0px; font-size: 5.14pt;" id="TRGRRTFtoHTMLTab">&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;</font><font style="font-family: 'Times New Roman';">[ ]</font></div>
        </td>
      </tr>
      <tr>
        <td style="width: 6.82%; vertical-align: top; border-bottom: #000000 1px solid;">&#160;</td>
        <td style="width: 93.18%; vertical-align: top; border-bottom: #000000 1px solid;">
          <div>&#160;</div>
          <div style="margin-top: 3pt;"><font style="font-family: 'Times New Roman';">(b)</font><font style="text-indent: 0px; font-size: 5.14pt;" id="TRGRRTFtoHTMLTab">&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;</font><font style="font-family: 'Times New Roman';">[x]</font></div>
        </td>
      </tr>
      <tr>
        <td style="width: 6.82%; vertical-align: top; border-top: #000000 1px solid; border-bottom: #000000 1px solid;">
          <div>&#160;</div>
          <div style="margin-top: 3pt; font-family: 'Times New Roman';">3</div>
        </td>
        <td style="width: 93.18%; vertical-align: top; border-top: #000000 1px solid; border-bottom: #000000 1px solid;">
          <div>&#160;</div>
          <div style="margin-top: 3pt; font-family: 'Times New Roman';">SEC Use Only</div>
        </td>
      </tr>
      <tr>
        <td style="width: 6.82%; vertical-align: top; border-top: #000000 1px solid; border-bottom: #000000 1px solid;">
          <div>&#160;</div>
          <div style="margin-top: 3pt; font-family: 'Times New Roman';">4</div>
        </td>
        <td style="width: 93.18%; vertical-align: top; border-top: #000000 1px solid; border-bottom: #000000 1px solid;">
          <div>&#160;</div>
          <div style="margin-top: 3pt; font-family: 'Times New Roman';">Citizenship or Place of Organization.</div>
          <div>&#160;</div>
          <div style="margin-bottom: 6pt; font-family: 'Times New Roman';">Delaware</div>
          <div>&#160;</div>
        </td>
      </tr>

  </table>
  <div><br>
  </div>
  <table style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%; border-collapse: collapse; text-align: left; color: #000000;" cellpadding="0" cellspacing="0">

      <tr>
        <td rowspan="4" style="width: 17.69%; vertical-align: middle; border-top: #000000 1px solid; border-bottom: #000000 1px solid;">
          <div>&#160;</div>
          <div style="text-align: center; margin-top: 3pt; font-family: 'Times New Roman';">Number</div>
          <div style="text-align: center; margin-top: 3pt; font-family: 'Times New Roman';">of Shares</div>
          <div style="text-align: center; margin-top: 3pt; font-family: 'Times New Roman';">Beneficially</div>
          <div style="text-align: center; margin-top: 3pt; font-family: 'Times New Roman';">Owned by</div>
          <div style="text-align: center; margin-top: 3pt; font-family: 'Times New Roman';">Each</div>
          <div style="text-align: center; margin-top: 3pt; font-family: 'Times New Roman';">Reporting</div>
          <div style="text-align: center; margin-top: 3pt; font-family: 'Times New Roman';">Person With</div>
        </td>
        <td style="width: 82.31%; vertical-align: middle; border-top: #000000 1px solid; border-bottom: #000000 1px solid;">
          <div>&#160;</div>
          <div style="margin-top: 3pt;"><font style="font-family: 'Times New Roman';">5</font><font style="text-indent: 0px; font-size: 6pt;" id="TRGRRTFtoHTMLTab">&#160;&#160;</font><font style="font-family: 'Times New Roman';">Sole Voting Power</font></div>
          <div>&#160;</div>
          <div style="margin-bottom: 6pt; font-family: 'Times New Roman';">0 shares</div>
          <div>&#160;</div>
        </td>
      </tr>
      <tr>
        <td style="width: 93.05%; vertical-align: middle; border-top: #000000 1px solid; border-bottom: #000000 1px solid;">
          <div>&#160;</div>
          <div style="margin-top: 3pt;"><font style="font-family: 'Times New Roman';">6</font><font style="text-indent: 0px; font-size: 6pt;" id="TRGRRTFtoHTMLTab">&#160;&#160;</font><font style="font-family: 'Times New Roman';">Shared Voting Power</font></div>
          <div>&#160;</div>
          <div style="font-family: 'Times New Roman';">1,762,115 shares</div>
          <div>&#160;</div>
          <div style="margin-left: 12pt; margin-top: 3pt; font-family: 'Times New Roman';">Refer to Item 4 below.</div>
        </td>
      </tr>
      <tr>
        <td style="width: 93.05%; vertical-align: middle; border-top: #000000 1px solid; border-bottom: #000000 1px solid;">
          <div>&#160;</div>
          <div style="margin-top: 3pt;"><font style="font-family: 'Times New Roman';">7</font><font style="text-indent: 0px; font-size: 6pt;" id="TRGRRTFtoHTMLTab">&#160;&#160;</font><font style="font-family: 'Times New Roman';">Sole Dispositive Power</font></div>
          <div>&#160;</div>
          <div style="margin-bottom: 6pt; font-family: 'Times New Roman';">0 shares</div>
          <div>&#160;</div>
        </td>
      </tr>
      <tr>
        <td style="width: 93.05%; vertical-align: middle; border-top: #000000 1px solid; border-bottom: #000000 1px solid;">
          <div>&#160;</div>
          <div style="margin-top: 3pt;"><font style="font-family: 'Times New Roman';">8</font><font style="text-indent: 0px; font-size: 6pt;" id="TRGRRTFtoHTMLTab">&#160;&#160;</font><font style="font-family: 'Times New Roman';">Shared Dispositive Power</font></div>
          <div>&#160;</div>
          <div style="margin-bottom: 6pt; font-family: 'Times New Roman';">1,762,115 shares</div>
          <div style="margin-left: 12pt; margin-top: 3pt; font-family: 'Times New Roman';">Refer to Item 4 below.</div>
        </td>
      </tr>

  </table>
  <div><br>
  </div>
  <table style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%; border-collapse: collapse; text-align: left; color: #000000;" cellpadding="0" cellspacing="0">

      <tr>
        <td style="width: 6.82%; vertical-align: top; border-top: #000000 1px solid; border-bottom: #000000 1px solid;">
          <div>&#160;</div>
          <div style="margin-top: 3pt; font-family: 'Times New Roman';">9</div>
        </td>
        <td style="width: 93.05%; vertical-align: top; border-top: #000000 1px solid; border-bottom: #000000 1px solid;">
          <div>&#160;</div>
          <div style="margin-top: 3pt; font-family: 'Times New Roman';">Aggregate Amount Beneficially Owned by Each Reporting Person</div>
          <div>&#160;</div>
          <div style="font-family: 'Times New Roman';">1,762,115 shares</div>
          <div style="margin-top: 6pt; font-family: 'Times New Roman';">Refer to Item 4 below.</div>
        </td>
        <td style="width: 0.13%; vertical-align: top;">&#160;</td>
      </tr>
      <tr>
        <td style="width: 6.82%; vertical-align: top; border-top: #000000 1px solid; border-bottom: #000000 1px solid;">
          <div>&#160;</div>
          <div style="margin-top: 3pt; font-family: 'Times New Roman';">10</div>
        </td>
        <td style="width: 93.05%; vertical-align: top; border-top: #000000 1px solid; border-bottom: #000000 1px solid;">
          <div>&#160;</div>
          <div style="text-align: justify; margin-top: 3pt; font-family: 'Times New Roman';">Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions)</div>
          <div style="text-align: justify; margin-top: 3pt; font-family: 'Times New Roman';">&#160;&#160;&#160;&#160;[ ] <font style="color: #000000;">N/A</font></div>
        </td>
        <td style="width: 0.13%; vertical-align: top;">&#160;</td>
      </tr>
      <tr>
        <td style="width: 6.82%; vertical-align: top; border-top: #000000 1px solid; border-bottom: #000000 1px solid;">
          <div>&#160;</div>
          <div style="margin-top: 3pt; font-family: 'Times New Roman';">11</div>
        </td>
        <td style="width: 93.05%; vertical-align: top; border-top: #000000 1px solid; border-bottom: #000000 1px solid;">
          <div>&#160;</div>
          <div style="margin-top: 3pt; font-family: 'Times New Roman';">Percent of Class Represented by Amount in Row (9)*</div>
          <div>&#160;</div>
          <div style="font-family: 'Times New Roman';">4.70%</div>
          <div style="margin-top: 6pt; font-family: 'Times New Roman';">Refer to Item 4 below.</div>
        </td>
        <td style="width: 0.13%; vertical-align: top;">&#160;</td>
      </tr>
      <tr>
        <td style="width: 6.82%; vertical-align: top; border-top: #000000 1px solid; border-bottom: #000000 1px solid;">
          <div>&#160;</div>
          <div style="margin-top: 3pt; font-family: 'Times New Roman';">12</div>
        </td>
        <td style="width: 93.05%; vertical-align: top; border-top: #000000 1px solid; border-bottom: #000000 1px solid;">
          <div>&#160;</div>
          <div style="margin-top: 3pt; font-family: 'Times New Roman';">Type of Reporting Person (See Instructions)</div>
          <div style="margin-top: 12pt; font-family: 'Times New Roman';">PN (Partnership)</div>
        </td>
        <td style="width: 0.13%; vertical-align: top;">&#160;</td>
      </tr>

  </table>
  <div><br>
  </div>
  <div style="clear: both; margin-top: 10pt; margin-bottom: 10pt;" id="DSPFPageBreakArea">
    <div style="page-break-after:always;" id="DSPFPageBreak">
      <hr style="margin: 4px 0px; width: 100%; border-width: 0; height: 2px; color: #000000; background-color: #000000; clear: both;" noshade="noshade"></div>
  </div>
  <table style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%; border-collapse: collapse; text-align: left; color: #000000;" id="z2a3e65d9ae6a4a979d18415e22e9bbe5" cellpadding="0" cellspacing="0">

      <tr>
        <td style="width: 6.82%; vertical-align: top; border-top: #000000 1px solid; border-bottom: #000000 1px solid;">
          <div>&#160;</div>
          <div style="margin-top: 3pt; font-family: 'Times New Roman';">1</div>
        </td>
        <td style="width: 93.18%; vertical-align: top; border-top: #000000 1px solid; border-bottom: #000000 1px solid;">
          <div>&#160;</div>
          <div style="margin-top: 3pt; font-family: 'Times New Roman';">Names of Reporting Persons.</div>
          <div style="margin-top: 3pt; font-family: 'Times New Roman';">I.R.S. Identification Nos. of above persons (entities only)</div>
          <div>&#160;</div>
          <div style="font-family: 'Times New Roman';">Cormorant Private Healthcare GP II, LLC</div>
          <div>&#160;</div>
        </td>
      </tr>
      <tr>
        <td style="width: 6.82%; vertical-align: top; border-top: #000000 1px solid;">
          <div>&#160;</div>
          <div style="margin-top: 3pt; font-family: 'Times New Roman';">2</div>
        </td>
        <td style="width: 93.18%; vertical-align: top; border-top: #000000 1px solid;">
          <div>&#160;</div>
          <div style="margin-top: 3pt; font-family: 'Times New Roman';">Check the Appropriate Box if a Member of a Group (See Instructions)</div>
        </td>
      </tr>
      <tr>
        <td style="width: 6.82%; vertical-align: top;">&#160;</td>
        <td style="width: 93.18%; vertical-align: top;">
          <div>&#160;</div>
          <div style="margin-top: 3pt;"><font style="font-family: 'Times New Roman';">(a)</font><font style="text-indent: 0px; font-size: 5.14pt;" id="TRGRRTFtoHTMLTab">&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;</font><font style="font-family: 'Times New Roman';">[ ]</font></div>
        </td>
      </tr>
      <tr>
        <td style="width: 6.82%; vertical-align: top; border-bottom: #000000 1px solid;">&#160;</td>
        <td style="width: 93.18%; vertical-align: top; border-bottom: #000000 1px solid;">
          <div>&#160;</div>
          <div style="margin-top: 3pt;"><font style="font-family: 'Times New Roman';">(b)</font><font style="text-indent: 0px; font-size: 5.14pt;" id="TRGRRTFtoHTMLTab">&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;</font><font style="font-family: 'Times New Roman';">[x]</font></div>
        </td>
      </tr>
      <tr>
        <td style="width: 6.82%; vertical-align: top; border-top: #000000 1px solid; border-bottom: #000000 1px solid;">
          <div>&#160;</div>
          <div style="margin-top: 3pt; font-family: 'Times New Roman';">3</div>
        </td>
        <td style="width: 93.18%; vertical-align: top; border-top: #000000 1px solid; border-bottom: #000000 1px solid;">
          <div>&#160;</div>
          <div style="margin-top: 3pt; font-family: 'Times New Roman';">SEC Use Only</div>
        </td>
      </tr>
      <tr>
        <td style="width: 6.82%; vertical-align: top; border-top: #000000 1px solid; border-bottom: #000000 1px solid;">
          <div>&#160;</div>
          <div style="margin-top: 3pt; font-family: 'Times New Roman';">4</div>
        </td>
        <td style="width: 93.18%; vertical-align: top; border-top: #000000 1px solid; border-bottom: #000000 1px solid;">
          <div>&#160;</div>
          <div style="margin-top: 3pt; font-family: 'Times New Roman';">Citizenship or Place of Organization.</div>
          <div>&#160;</div>
          <div style="margin-bottom: 6pt; font-family: 'Times New Roman';">Delaware</div>
          <div>&#160;</div>
        </td>
      </tr>

  </table>
  <div><br>
  </div>
  <table style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%; border-collapse: collapse; text-align: left; color: #000000;" cellpadding="0" cellspacing="0">

      <tr>
        <td rowspan="4" style="width: 17.69%; vertical-align: middle; border-top: #000000 1px solid; border-bottom: #000000 1px solid;">
          <div>&#160;</div>
          <div style="text-align: center; margin-top: 3pt; font-family: 'Times New Roman';">Number</div>
          <div style="text-align: center; margin-top: 3pt; font-family: 'Times New Roman';">of Shares</div>
          <div style="text-align: center; margin-top: 3pt; font-family: 'Times New Roman';">Beneficially</div>
          <div style="text-align: center; margin-top: 3pt; font-family: 'Times New Roman';">Owned by</div>
          <div style="text-align: center; margin-top: 3pt; font-family: 'Times New Roman';">Each</div>
          <div style="text-align: center; margin-top: 3pt; font-family: 'Times New Roman';">Reporting</div>
          <div style="text-align: center; margin-top: 3pt; font-family: 'Times New Roman';">Person With</div>
        </td>
        <td style="width: 82.31%; vertical-align: middle; border-top: #000000 1px solid; border-bottom: #000000 1px solid;">
          <div>&#160;</div>
          <div style="margin-top: 3pt;"><font style="font-family: 'Times New Roman';">5</font><font style="text-indent: 0px; font-size: 6pt;" id="TRGRRTFtoHTMLTab">&#160;&#160;</font><font style="font-family: 'Times New Roman';">Sole Voting Power</font></div>
          <div>&#160;</div>
          <div style="margin-bottom: 6pt; font-family: 'Times New Roman';">0 shares</div>
          <div>&#160;</div>
        </td>
      </tr>
      <tr>
        <td style="width: 93.05%; vertical-align: middle; border-top: #000000 1px solid; border-bottom: #000000 1px solid;">
          <div>&#160;</div>
          <div style="margin-top: 3pt;"><font style="font-family: 'Times New Roman';">6</font><font style="text-indent: 0px; font-size: 6pt;" id="TRGRRTFtoHTMLTab">&#160;&#160;</font><font style="font-family: 'Times New Roman';">Shared Voting Power</font></div>
          <div>&#160;</div>
          <div style="font-family: 'Times New Roman';">1,762,115 shares</div>
          <div><font style="font-family: 'Times New Roman';"> </font>&#160;</div>
          <div style="margin-left: 12pt; margin-top: 3pt; font-family: 'Times New Roman';">Refer to Item 4 below.</div>
        </td>
      </tr>
      <tr>
        <td style="width: 93.05%; vertical-align: middle; border-top: #000000 1px solid; border-bottom: #000000 1px solid;">
          <div>&#160;</div>
          <div style="margin-top: 3pt;"><font style="font-family: 'Times New Roman';">7</font><font style="text-indent: 0px; font-size: 6pt;" id="TRGRRTFtoHTMLTab">&#160;&#160;</font><font style="font-family: 'Times New Roman';">Sole Dispositive Power</font></div>
          <div>&#160;</div>
          <div style="margin-bottom: 6pt; font-family: 'Times New Roman';">0 shares</div>
          <div>&#160;</div>
        </td>
      </tr>
      <tr>
        <td style="width: 93.05%; vertical-align: middle; border-top: #000000 1px solid; border-bottom: #000000 1px solid;">
          <div>&#160;</div>
          <div style="margin-top: 3pt;"><font style="font-family: 'Times New Roman';">8</font><font style="text-indent: 0px; font-size: 6pt;" id="TRGRRTFtoHTMLTab">&#160;&#160;</font><font style="font-family: 'Times New Roman';">Shared Dispositive Power</font></div>
          <div>&#160;</div>
          <div style="font-family: 'Times New Roman';">1,762,115 shares</div>
          <div style="margin-left: 12pt; margin-top: 6pt; font-family: 'Times New Roman';">Refer to Item 4 below.</div>
        </td>
      </tr>

  </table>
  <div><br>
  </div>
  <table style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%; border-collapse: collapse; text-align: left; color: #000000;" cellpadding="0" cellspacing="0">

      <tr>
        <td style="width: 6.82%; vertical-align: top; border-top: #000000 1px solid; border-bottom: #000000 1px solid;">
          <div>&#160;</div>
          <div style="margin-top: 3pt; font-family: 'Times New Roman';">9</div>
        </td>
        <td style="width: 93.05%; vertical-align: top; border-top: #000000 1px solid; border-bottom: #000000 1px solid;">
          <div>&#160;</div>
          <div style="margin-top: 3pt; font-family: 'Times New Roman';">Aggregate Amount Beneficially Owned by Each Reporting Person</div>
          <div>&#160;</div>
          <div style="margin-bottom: 6pt; font-family: 'Times New Roman';">1,762,115 shares</div>
          <div style="margin-top: 3pt; font-family: 'Times New Roman';">Refer to Item 4 below.</div>
        </td>
        <td style="width: 0.13%; vertical-align: top;">&#160;</td>
      </tr>
      <tr>
        <td style="width: 6.82%; vertical-align: top; border-top: #000000 1px solid; border-bottom: #000000 1px solid;">
          <div>&#160;</div>
          <div style="margin-top: 3pt; font-family: 'Times New Roman';">10</div>
        </td>
        <td style="width: 93.05%; vertical-align: top; border-top: #000000 1px solid; border-bottom: #000000 1px solid;">
          <div>&#160;</div>
          <div style="text-align: justify; margin-top: 3pt; font-family: 'Times New Roman';">Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions)</div>
          <div style="text-align: justify; margin-top: 3pt; font-family: 'Times New Roman';">&#160;&#160;&#160;&#160;[ ] <font style="color: #000000;">N/A</font></div>
        </td>
        <td style="width: 0.13%; vertical-align: top;">&#160;</td>
      </tr>
      <tr>
        <td style="width: 6.82%; vertical-align: top; border-top: #000000 1px solid; border-bottom: #000000 1px solid;">
          <div>&#160;</div>
          <div style="margin-top: 3pt; font-family: 'Times New Roman';">11</div>
        </td>
        <td style="width: 93.05%; vertical-align: top; border-top: #000000 1px solid; border-bottom: #000000 1px solid;">
          <div>&#160;</div>
          <div style="margin-top: 3pt; font-family: 'Times New Roman';">Percent of Class Represented by Amount in Row (9)*</div>
          <div>&#160;</div>
          <div style="margin-bottom: 6pt; font-family: 'Times New Roman';">4.70%</div>
          <div style="margin-top: 3pt; font-family: 'Times New Roman';">Refer to Item 4 below.</div>
        </td>
        <td style="width: 0.13%; vertical-align: top;">&#160;</td>
      </tr>
      <tr>
        <td style="width: 6.82%; vertical-align: top; border-top: #000000 1px solid; border-bottom: #000000 1px solid;">
          <div>&#160;</div>
          <div style="margin-top: 3pt; font-family: 'Times New Roman';">12</div>
        </td>
        <td style="width: 93.05%; vertical-align: top; border-top: #000000 1px solid; border-bottom: #000000 1px solid;">
          <div>&#160;</div>
          <div style="margin-top: 3pt; font-family: 'Times New Roman';">Type of Reporting Person (See Instructions)</div>
          <div style="margin-top: 3pt; margin-bottom: 3pt;">&#160;</div>
          <div style="margin-bottom: 6pt; font-family: 'Times New Roman';">OO (Limited Liability Company)</div>
          <div>&#160;</div>
        </td>
        <td style="width: 0.13%; vertical-align: top;">&#160;</td>
      </tr>

  </table>
  <div><br>
  </div>
  <div id="DSPFPageBreakArea" style="clear: both; margin-top: 10pt; margin-bottom: 10pt;">
    <div id="DSPFPageBreak" style="page-break-after: always;">
      <hr style="border-width: 0px; clear: both; margin: 4px 0px; width: 100%; height: 2px; color: #000000; background-color: #000000;" noshade="noshade"></div>
  </div>
  <table style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%; border-collapse: collapse; text-align: left; color: #000000;" cellpadding="0" cellspacing="0">

      <tr>
        <td style="width: 6.82%; vertical-align: top; border-top: #000000 1px solid; border-bottom: #000000 1px solid;">
          <div>&#160;</div>
          <div style="margin-top: 3pt; font-family: 'Times New Roman';">1</div>
        </td>
        <td style="width: 93.18%; vertical-align: top; border-top: #000000 1px solid; border-bottom: #000000 1px solid;">
          <div>&#160;</div>
          <div style="margin-top: 3pt; font-family: 'Times New Roman';">Names of Reporting Persons.</div>
          <div style="margin-top: 3pt; font-family: 'Times New Roman';">I.R.S. Identification Nos. of above persons (entities only)</div>
          <div>&#160;</div>
          <div style="font-family: 'Times New Roman';">Cormorant Asset Management, LP</div>
          <div>&#160;</div>
        </td>
      </tr>
      <tr>
        <td style="width: 6.82%; vertical-align: top; border-top: #000000 1px solid;">
          <div>&#160;</div>
          <div style="margin-top: 3pt; font-family: 'Times New Roman';">2</div>
        </td>
        <td style="width: 93.18%; vertical-align: top; border-top: #000000 1px solid;">
          <div>&#160;</div>
          <div style="margin-top: 3pt; font-family: 'Times New Roman';">Check the Appropriate Box if a Member of a Group (See Instructions)</div>
        </td>
      </tr>
      <tr>
        <td style="width: 6.82%; vertical-align: top;">&#160;</td>
        <td style="width: 93.18%; vertical-align: top;">
          <div>&#160;</div>
          <div style="margin-top: 3pt;"><font style="font-family: 'Times New Roman';">(a)</font><font style="text-indent: 0px; font-size: 5.14pt;" id="TRGRRTFtoHTMLTab">&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;</font><font style="font-family: 'Times New Roman';">[ ]</font></div>
        </td>
      </tr>
      <tr>
        <td style="width: 6.82%; vertical-align: top; border-bottom: #000000 1px solid;">&#160;</td>
        <td style="width: 93.18%; vertical-align: top; border-bottom: #000000 1px solid;">
          <div>&#160;</div>
          <div style="margin-top: 3pt;"><font style="font-family: 'Times New Roman';">(b)</font><font style="text-indent: 0px; font-size: 5.14pt;" id="TRGRRTFtoHTMLTab">&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;</font><font style="font-family: 'Times New Roman';">[x]</font></div>
        </td>
      </tr>
      <tr>
        <td style="width: 6.82%; vertical-align: top; border-top: #000000 1px solid; border-bottom: #000000 1px solid;">
          <div>&#160;</div>
          <div style="margin-top: 3pt; font-family: 'Times New Roman';">3</div>
        </td>
        <td style="width: 93.18%; vertical-align: top; border-top: #000000 1px solid; border-bottom: #000000 1px solid;">
          <div>&#160;</div>
          <div style="margin-top: 3pt; font-family: 'Times New Roman';">SEC Use Only</div>
        </td>
      </tr>
      <tr>
        <td style="width: 6.82%; vertical-align: top; border-top: #000000 1px solid; border-bottom: #000000 1px solid;">
          <div>&#160;</div>
          <div style="margin-top: 3pt; font-family: 'Times New Roman';">4</div>
        </td>
        <td style="width: 93.18%; vertical-align: top; border-top: #000000 1px solid; border-bottom: #000000 1px solid;">
          <div>&#160;</div>
          <div style="margin-top: 3pt; font-family: 'Times New Roman';">Citizenship or Place of Organization.</div>
          <div>&#160;</div>
          <div style="margin-bottom: 6pt; font-family: 'Times New Roman';">Delaware</div>
          <div>&#160;</div>
        </td>
      </tr>

  </table>
  <div><br>
  </div>
  <table style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%; border-collapse: collapse; text-align: left; color: #000000;" cellpadding="0" cellspacing="0">

      <tr>
        <td rowspan="4" style="width: 17.69%; vertical-align: middle; border-top: #000000 1px solid; border-bottom: #000000 1px solid;">
          <div>&#160;</div>
          <div style="text-align: center; margin-top: 3pt; font-family: 'Times New Roman';">Number</div>
          <div style="text-align: center; margin-top: 3pt; font-family: 'Times New Roman';">of Shares</div>
          <div style="text-align: center; margin-top: 3pt; font-family: 'Times New Roman';">Beneficially</div>
          <div style="text-align: center; margin-top: 3pt; font-family: 'Times New Roman';">Owned by</div>
          <div style="text-align: center; margin-top: 3pt; font-family: 'Times New Roman';">Each</div>
          <div style="text-align: center; margin-top: 3pt; font-family: 'Times New Roman';">Reporting</div>
          <div style="text-align: center; margin-top: 3pt; font-family: 'Times New Roman';">Person With</div>
        </td>
        <td style="width: 82.31%; vertical-align: middle; border-top: #000000 1px solid; border-bottom: #000000 1px solid;">
          <div>&#160;</div>
          <div style="margin-top: 3pt;"><font style="font-family: 'Times New Roman';">5</font><font style="text-indent: 0px; font-size: 6pt;" id="TRGRRTFtoHTMLTab">&#160;&#160;</font><font style="font-family: 'Times New Roman';">Sole Voting Power</font></div>
          <div>&#160;</div>
          <div style="margin-bottom: 6pt; font-family: 'Times New Roman';">0 shares</div>
          <div>&#160;</div>
        </td>
      </tr>
      <tr>
        <td style="width: 93.05%; vertical-align: middle; border-top: #000000 1px solid; border-bottom: #000000 1px solid;">
          <div>&#160;</div>
          <div style="margin-top: 3pt;"><font style="font-family: 'Times New Roman';">6</font><font style="text-indent: 0px; font-size: 6pt;" id="TRGRRTFtoHTMLTab">&#160;&#160;</font><font style="font-family: 'Times New Roman';">Shared Voting Power</font></div>
          <div>&#160;</div>
          <div style="font-family: 'Times New Roman';">2,464,547 shares</div>
          <div style="margin-left: 12pt; margin-top: 6pt; font-family: 'Times New Roman';">Refer to Item 4 below.</div>
        </td>
      </tr>
      <tr>
        <td style="width: 93.05%; vertical-align: middle; border-top: #000000 1px solid; border-bottom: #000000 1px solid;">
          <div>&#160;</div>
          <div style="margin-top: 3pt;"><font style="font-family: 'Times New Roman';">7</font><font style="text-indent: 0px; font-size: 6pt;" id="TRGRRTFtoHTMLTab">&#160;&#160;</font><font style="font-family: 'Times New Roman';">Sole Dispositive Power</font></div>
          <div>&#160;</div>
          <div style="margin-bottom: 6pt; font-family: 'Times New Roman';">0 shares</div>
          <div>&#160;</div>
        </td>
      </tr>
      <tr>
        <td style="width: 93.05%; vertical-align: middle; border-top: #000000 1px solid; border-bottom: #000000 1px solid;">
          <div>&#160;</div>
          <div style="margin-top: 3pt;"><font style="font-family: 'Times New Roman';">8</font><font style="text-indent: 0px; font-size: 6pt;" id="TRGRRTFtoHTMLTab">&#160;&#160;</font><font style="font-family: 'Times New Roman';">Shared Dispositive Power</font></div>
          <div>&#160;</div>
          <div style="font-family: 'Times New Roman';">2,464,547 shares</div>
          <div style="margin-left: 12pt; margin-top: 6pt; font-family: 'Times New Roman';">Refer to Item 4 below.</div>
        </td>
      </tr>

  </table>
  <div><br>
  </div>
  <table style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%; border-collapse: collapse; text-align: left; color: #000000;" cellpadding="0" cellspacing="0">

      <tr>
        <td style="width: 6.82%; vertical-align: top; border-top: #000000 1px solid; border-bottom: #000000 1px solid;">
          <div>&#160;</div>
          <div style="margin-top: 3pt; font-family: 'Times New Roman';">9</div>
        </td>
        <td style="width: 93.05%; vertical-align: top; border-top: #000000 1px solid; border-bottom: #000000 1px solid;">
          <div>&#160;</div>
          <div style="margin-top: 3pt; font-family: 'Times New Roman';">Aggregate Amount Beneficially Owned by Each Reporting Person</div>
          <div>&#160;</div>
          <div style="margin-bottom: 6pt; font-family: 'Times New Roman';">2,464,547 shares</div>
          <div style="margin-top: 3pt; font-family: 'Times New Roman';">Refer to Item 4 below.</div>
        </td>
        <td style="width: 0.13%; vertical-align: top;">&#160;</td>
      </tr>
      <tr>
        <td style="width: 6.82%; vertical-align: top; border-top: #000000 1px solid; border-bottom: #000000 1px solid;">
          <div>&#160;</div>
          <div style="margin-top: 3pt; font-family: 'Times New Roman';">10</div>
        </td>
        <td style="width: 93.05%; vertical-align: top; border-top: #000000 1px solid; border-bottom: #000000 1px solid;">
          <div>&#160;</div>
          <div style="text-align: justify; margin-top: 3pt; font-family: 'Times New Roman';">Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions)</div>
          <div style="text-align: justify; margin-top: 3pt; font-family: 'Times New Roman';">&#160;&#160;&#160;&#160;[ ] <font style="color: #000000;">N/A</font></div>
        </td>
        <td style="width: 0.13%; vertical-align: top;">&#160;</td>
      </tr>
      <tr>
        <td style="width: 6.82%; vertical-align: top; border-top: #000000 1px solid; border-bottom: #000000 1px solid;">
          <div>&#160;</div>
          <div style="margin-top: 3pt; font-family: 'Times New Roman';">11</div>
        </td>
        <td style="width: 93.05%; vertical-align: top; border-top: #000000 1px solid; border-bottom: #000000 1px solid;">
          <div>&#160;</div>
          <div style="margin-top: 3pt; font-family: 'Times New Roman';">Percent of Class Represented by Amount in Row (9)*</div>
          <div style="margin-top: 3pt;">&#160;</div>
          <div style="font-family: 'Times New Roman';">6.57%</div>
          <div style="margin-top: 6pt; font-family: 'Times New Roman';">Refer to Item 4 below.</div>
        </td>
        <td style="width: 0.13%; vertical-align: top;">&#160;</td>
      </tr>
      <tr>
        <td style="width: 6.82%; vertical-align: top; border-top: #000000 1px solid; border-bottom: #000000 1px solid;">
          <div>&#160;</div>
          <div style="margin-top: 3pt; font-family: 'Times New Roman';">12</div>
        </td>
        <td style="width: 93.05%; vertical-align: top; border-top: #000000 1px solid; border-bottom: #000000 1px solid;">
          <div>&#160;</div>
          <div style="margin-top: 3pt; font-family: 'Times New Roman';">Type of Reporting Person (See Instructions)</div>
          <div style="margin-top: 3pt; margin-bottom: 3pt;">&#160;</div>
          <div style="margin-bottom: 6pt; font-family: 'Times New Roman';">PN (Partnership)</div>
          <div>&#160;</div>
        </td>
        <td style="width: 0.13%; vertical-align: top;">&#160;</td>
      </tr>

  </table>
  <div><br>
  </div>
  <div id="DSPFPageBreakArea" style="clear: both; margin-top: 10pt; margin-bottom: 10pt;">
    <div id="DSPFPageBreak" style="page-break-after: always;">
      <hr style="border-width: 0px; clear: both; margin: 4px 0px; width: 100%; height: 2px; color: #000000; background-color: #000000;" noshade="noshade"></div>
  </div>
  <table style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%; border-collapse: collapse; text-align: left; color: #000000;" cellpadding="0" cellspacing="0">

      <tr>
        <td style="width: 6.82%; vertical-align: top; border-top: #000000 1px solid; border-bottom: #000000 1px solid;">
          <div>&#160;</div>
          <div style="margin-top: 3pt; font-family: 'Times New Roman';">1</div>
        </td>
        <td style="width: 93.18%; vertical-align: top; border-top: #000000 1px solid; border-bottom: #000000 1px solid;">
          <div>&#160;</div>
          <div style="margin-top: 3pt; font-family: 'Times New Roman';">Names of Reporting Persons.</div>
          <div style="margin-top: 3pt; font-family: 'Times New Roman';">I.R.S. Identification Nos. of above persons (entities only)</div>
          <div>&#160;</div>
          <div style="font-family: 'Times New Roman';">Bihua Chen</div>
          <div>&#160;</div>
        </td>
      </tr>
      <tr>
        <td style="width: 6.82%; vertical-align: top; border-top: #000000 1px solid;">
          <div>&#160;</div>
          <div style="margin-top: 3pt; font-family: 'Times New Roman';">2</div>
        </td>
        <td style="width: 93.18%; vertical-align: top; border-top: #000000 1px solid;">
          <div>&#160;</div>
          <div style="margin-top: 3pt; font-family: 'Times New Roman';">Check the Appropriate Box if a Member of a Group (See Instructions)</div>
        </td>
      </tr>
      <tr>
        <td style="width: 6.82%; vertical-align: top;">&#160;</td>
        <td style="width: 93.18%; vertical-align: top;">
          <div>&#160;</div>
          <div style="margin-top: 3pt;"><font style="font-family: 'Times New Roman';">(a)</font><font style="text-indent: 0px; font-size: 5.14pt;" id="TRGRRTFtoHTMLTab">&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;</font><font style="font-family: 'Times New Roman';">[ ]</font></div>
        </td>
      </tr>
      <tr>
        <td style="width: 6.82%; vertical-align: top; border-bottom: #000000 1px solid;">&#160;</td>
        <td style="width: 93.18%; vertical-align: top; border-bottom: #000000 1px solid;">
          <div>&#160;</div>
          <div style="margin-top: 3pt;"><font style="font-family: 'Times New Roman';">(b)</font><font style="text-indent: 0px; font-size: 5.14pt;" id="TRGRRTFtoHTMLTab">&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;</font><font style="font-family: 'Times New Roman';">[x]</font></div>
        </td>
      </tr>
      <tr>
        <td style="width: 6.82%; vertical-align: top; border-top: #000000 1px solid; border-bottom: #000000 1px solid;">
          <div>&#160;</div>
          <div style="margin-top: 3pt; font-family: 'Times New Roman';">3</div>
        </td>
        <td style="width: 93.18%; vertical-align: top; border-top: #000000 1px solid; border-bottom: #000000 1px solid;">
          <div>&#160;</div>
          <div style="margin-top: 3pt; font-family: 'Times New Roman';">SEC Use Only</div>
        </td>
      </tr>
      <tr>
        <td style="width: 6.82%; vertical-align: top; border-top: #000000 1px solid; border-bottom: #000000 1px solid;">
          <div>&#160;</div>
          <div style="margin-top: 3pt; font-family: 'Times New Roman';">4</div>
        </td>
        <td style="width: 93.18%; vertical-align: top; border-top: #000000 1px solid; border-bottom: #000000 1px solid;">
          <div>&#160;</div>
          <div style="margin-top: 3pt; font-family: 'Times New Roman';">Citizenship or Place of Organization.</div>
          <div>&#160;</div>
          <div style="margin-bottom: 6pt; font-family: 'Times New Roman';">United States</div>
          <div>&#160;</div>
        </td>
      </tr>

  </table>
  <div><br>
  </div>
  <table style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%; border-collapse: collapse; text-align: left; color: #000000;" cellpadding="0" cellspacing="0">

      <tr>
        <td rowspan="4" style="width: 17.69%; vertical-align: middle; border-top: #000000 1px solid; border-bottom: #000000 1px solid;">
          <div>&#160;</div>
          <div style="text-align: center; margin-top: 3pt; font-family: 'Times New Roman';">Number</div>
          <div style="text-align: center; margin-top: 3pt; font-family: 'Times New Roman';">of Shares</div>
          <div style="text-align: center; margin-top: 3pt; font-family: 'Times New Roman';">Beneficially</div>
          <div style="text-align: center; margin-top: 3pt; font-family: 'Times New Roman';">Owned by</div>
          <div style="text-align: center; margin-top: 3pt; font-family: 'Times New Roman';">Each</div>
          <div style="text-align: center; margin-top: 3pt; font-family: 'Times New Roman';">Reporting</div>
          <div style="text-align: center; margin-top: 3pt; font-family: 'Times New Roman';">Person With</div>
        </td>
        <td style="width: 82.31%; vertical-align: middle; border-top: #000000 1px solid; border-bottom: #000000 1px solid;">
          <div>&#160;</div>
          <div style="margin-top: 3pt;"><font style="font-family: 'Times New Roman';">5</font><font style="text-indent: 0px; font-size: 6pt;" id="TRGRRTFtoHTMLTab">&#160;&#160;</font><font style="font-family: 'Times New Roman';">Sole Voting Power</font></div>
          <div>&#160;</div>
          <div style="margin-bottom: 6pt; font-family: 'Times New Roman';">0 shares</div>
          <div>&#160;</div>
        </td>
      </tr>
      <tr>
        <td style="width: 93.05%; vertical-align: middle; border-top: #000000 1px solid; border-bottom: #000000 1px solid;">
          <div>&#160;</div>
          <div style="margin-top: 3pt;"><font style="font-family: 'Times New Roman';">6</font><font style="text-indent: 0px; font-size: 6pt;" id="TRGRRTFtoHTMLTab">&#160;&#160;</font><font style="font-family: 'Times New Roman';">Shared Voting Power</font></div>
          <div>&#160;</div>
          <div style="font-family: 'Times New Roman';">2,464,547 shares</div>
          <div style="margin-left: 12pt; margin-top: 6pt; font-family: 'Times New Roman';">Refer to Item 4 below.</div>
        </td>
      </tr>
      <tr>
        <td style="width: 93.05%; vertical-align: middle; border-top: #000000 1px solid; border-bottom: #000000 1px solid;">
          <div>&#160;</div>
          <div style="margin-top: 3pt;"><font style="font-family: 'Times New Roman';">7</font><font style="text-indent: 0px; font-size: 6pt;" id="TRGRRTFtoHTMLTab">&#160;&#160;</font><font style="font-family: 'Times New Roman';">Sole Dispositive Power</font></div>
          <div>&#160;</div>
          <div style="font-family: 'Times New Roman';">0 shares</div>
        </td>
      </tr>
      <tr>
        <td style="width: 93.05%; vertical-align: middle; border-top: #000000 1px solid; border-bottom: #000000 1px solid;">
          <div>&#160;</div>
          <div style="margin-top: 3pt;"><font style="font-family: 'Times New Roman';">8</font><font style="text-indent: 0px; font-size: 6pt;" id="TRGRRTFtoHTMLTab">&#160;&#160;</font><font style="font-family: 'Times New Roman';">Shared Dispositive Power</font></div>
          <div>&#160;</div>
          <div style="font-family: 'Times New Roman';">2,464,547 shares</div>
          <div style="margin-left: 12pt; margin-top: 6pt; font-family: 'Times New Roman';">Refer to Item 4 below.</div>
        </td>
      </tr>

  </table>
  <div><br>
  </div>
  <table style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%; border-collapse: collapse; text-align: left; color: #000000;" cellpadding="0" cellspacing="0">

      <tr>
        <td style="width: 6.82%; vertical-align: top; border-top: #000000 1px solid; border-bottom: #000000 1px solid;">
          <div>&#160;</div>
          <div style="margin-top: 3pt; font-family: 'Times New Roman';">9</div>
        </td>
        <td style="width: 93.05%; vertical-align: top; border-top: #000000 1px solid; border-bottom: #000000 1px solid;">
          <div>&#160;</div>
          <div style="margin-top: 3pt; font-family: 'Times New Roman';">Aggregate Amount Beneficially Owned by Each Reporting Person</div>
          <div>&#160;</div>
          <div style="font-family: 'Times New Roman';">2,464,547 shares</div>
          <div style="margin-top: 6pt; font-family: 'Times New Roman';">Refer to Item 4 below.</div>
        </td>
        <td style="width: 0.13%; vertical-align: top;">&#160;</td>
      </tr>
      <tr>
        <td style="width: 6.82%; vertical-align: top; border-top: #000000 1px solid; border-bottom: #000000 1px solid;">
          <div>&#160;</div>
          <div style="margin-top: 3pt; font-family: 'Times New Roman';">10</div>
        </td>
        <td style="width: 93.05%; vertical-align: top; border-top: #000000 1px solid; border-bottom: #000000 1px solid;">
          <div>&#160;</div>
          <div style="text-align: justify; margin-top: 3pt; font-family: 'Times New Roman';">Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions)</div>
          <div style="text-align: justify; margin-top: 3pt; font-family: 'Times New Roman';">&#160;&#160;&#160;&#160;[ ] <font style="color: #000000;">N/A</font></div>
        </td>
        <td style="width: 0.13%; vertical-align: top;">&#160;</td>
      </tr>
      <tr>
        <td style="width: 6.82%; vertical-align: top; border-top: #000000 1px solid; border-bottom: #000000 1px solid;">
          <div>&#160;</div>
          <div style="margin-top: 3pt; font-family: 'Times New Roman';">11</div>
        </td>
        <td style="width: 93.05%; vertical-align: top; border-top: #000000 1px solid; border-bottom: #000000 1px solid;">
          <div>&#160;</div>
          <div style="margin-top: 3pt; font-family: 'Times New Roman';">Percent of Class Represented by Amount in Row (9)*</div>
          <div>&#160;</div>
          <div style="margin-bottom: 6pt; font-family: 'Times New Roman';">6.57%</div>
          <div style="margin-top: 3pt; font-family: 'Times New Roman';">Refer to Item 4 below.</div>
        </td>
        <td style="width: 0.13%; vertical-align: top;">&#160;</td>
      </tr>
      <tr>
        <td style="width: 6.82%; vertical-align: top; border-top: #000000 1px solid; border-bottom: #000000 1px solid;">
          <div>&#160;</div>
          <div style="margin-top: 3pt; font-family: 'Times New Roman';">12</div>
        </td>
        <td style="width: 93.05%; vertical-align: top; border-top: #000000 1px solid; border-bottom: #000000 1px solid;">
          <div>&#160;</div>
          <div style="margin-top: 3pt; font-family: 'Times New Roman';">Type of Reporting Person (See Instructions)</div>
          <div style="margin-top: 3pt; margin-bottom: 3pt;">&#160;</div>
          <div style="margin-bottom: 6pt; font-family: 'Times New Roman';">IN (Individual)</div>
          <div>&#160;</div>
        </td>
        <td style="width: 0.13%; vertical-align: top;">&#160;</td>
      </tr>

  </table>
  <div style="clear: both; margin-top: 10pt; margin-bottom: 10pt;" id="DSPFPageBreakArea">
    <div style="page-break-after:always;" id="DSPFPageBreak">
      <hr style="margin: 4px 0px; width: 100%; border-width: 0; height: 2px; color: #000000; background-color: #000000; clear: both;" noshade="noshade"></div>
  </div>
  <div style="text-indent: -54pt; margin-left: 54pt; margin-bottom: 12pt; font-family: 'Times New Roman'; font-weight: bold;">Item&#160;1.</div>
  <table style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%; border-collapse: collapse; text-align: left; color: #000000;" id="zefcdd37b756346a4bac1a80eba678200" cellpadding="0" cellspacing="0">

      <tr>
        <td style="width: 7.07%; vertical-align: top;">
          <div style="font-family: 'Times New Roman';">(a)</div>
        </td>
        <td style="width: 92.93%; vertical-align: top;">
          <div style="font-family: 'Times New Roman';">Name of Issuer</div>
        </td>
      </tr>
      <tr>
        <td style="width: 7.07%; vertical-align: top;">&#160;</td>
        <td style="width: 92.93%; vertical-align: top;">
          <div>&#160;</div>
          <div style="margin-top: 6pt; font-family: 'Times New Roman';">Avidity Biosciences, Inc.</div>
          <div>&#160;</div>
        </td>
      </tr>
      <tr>
        <td style="width: 7.07%; vertical-align: top;">
          <div style="font-family: 'Times New Roman';">(b)</div>
        </td>
        <td style="width: 92.93%; vertical-align: top;">
          <div style="font-family: 'Times New Roman';">Address of Issuer&#8217;s Principal Executive Offices</div>
        </td>
      </tr>
      <tr>
        <td style="width: 7.07%; vertical-align: top;">&#160;</td>
        <td style="width: 92.93%; vertical-align: top;">
          <div>&#160;</div>
          <div style="color: #000000; font-family: 'Times New Roman';">10975 N. Torrey Pines Road, Suite 150, La Jolla, CA 92037</div>
        </td>
      </tr>

  </table>
  <div><br>
  </div>
  <div style="text-indent: -54pt; margin-left: 54pt; margin-bottom: 12pt; font-family: 'Times New Roman'; font-weight: bold;">Item&#160;2.</div>
  <table style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%; border-collapse: collapse; text-align: left; color: #000000;" id="z4be2546bc6db43d7b2cc5efdc56e8092" cellpadding="0" cellspacing="0">

      <tr>
        <td style="width: 7.07%; vertical-align: top;">
          <div style="font-family: 'Times New Roman';">(a)</div>
        </td>
        <td style="width: 92.93%; vertical-align: top;">
          <div style="font-family: 'Times New Roman';">Name of Person Filing</div>
        </td>
      </tr>
      <tr>
        <td style="width: 7.07%; vertical-align: top;">&#160;</td>
        <td style="width: 92.93%; vertical-align: top;">
          <div>&#160;</div>
          <div style="margin-top: 12pt; font-family: 'Times New Roman';">Cormorant Global Healthcare Master Fund, LP<br>
            Cormorant Global Healthcare GP, LLC</div>
          <div style="font-family: 'Times New Roman';">Cormorant Private Healthcare Fund II, LP</div>
          <div style="font-family: 'Times New Roman';">Cormorant Private Healthcare GP II, LLC</div>
          <div><font style="font-family: 'Times New Roman';">Cormorant Asset Management, LP<br>
              Bihua Chen<br>
            </font>&#160;</div>
        </td>
      </tr>
      <tr>
        <td style="width: 7.07%; vertical-align: top;">
          <div style="font-family: 'Times New Roman';">(b)</div>
        </td>
        <td style="width: 92.93%; vertical-align: top;">
          <div style="font-family: 'Times New Roman';">Address of Principal Business Office or, if none, Residence</div>
        </td>
      </tr>
      <tr>
        <td style="width: 7.07%; vertical-align: top;">&#160;</td>
        <td style="width: 92.93%; vertical-align: top;">
          <div>&#160;</div>
          <div style="margin-top: 12pt; font-family: 'Times New Roman';">200 Clarendon Street, 52nd Floor</div>
          <div style="font-family: 'Times New Roman';">Boston, MA 02116</div>
          <div>&#160;</div>
        </td>
      </tr>
      <tr>
        <td style="width: 7.07%; vertical-align: top;">
          <div style="font-family: 'Times New Roman';">(c)</div>
        </td>
        <td style="width: 92.93%; vertical-align: top;">
          <div style="font-family: 'Times New Roman';">Citizenship</div>
        </td>
      </tr>
      <tr>
        <td style="width: 7.07%; vertical-align: top;">&#160;</td>
        <td style="width: 92.93%; vertical-align: top;">
          <div>&#160;</div>
          <div style="font-family: 'Times New Roman';">Cormorant Global Healthcare Master Fund, LP - Cayman Islands<br>
            Cormorant Global Healthcare GP, LLC - Delaware</div>
          <div style="font-family: 'Times New Roman';">Cormorant Private Healthcare Fund II, LP - Delaware</div>
          <div style="font-family: 'Times New Roman';">Cormorant Private Healthcare GP II, LLC - Delaware</div>
          <div style="font-family: 'Times New Roman';">Cormorant Asset Management, LP - Delaware<br>
            Bihua Chen - United States</div>
          <div>&#160;</div>
        </td>
      </tr>
      <tr>
        <td style="width: 7.07%; vertical-align: top;">
          <div style="font-family: 'Times New Roman';">(d)</div>
        </td>
        <td style="width: 92.93%; vertical-align: top;">
          <div style="font-family: 'Times New Roman';">Title of Class of Securities</div>
        </td>
      </tr>
      <tr>
        <td style="width: 7.07%; vertical-align: top;">&#160;</td>
        <td style="width: 92.93%; vertical-align: top;">
          <div>&#160;</div>
          <div style="margin-top: 6pt; font-family: 'Times New Roman';">Common Stock</div>
          <div>&#160;</div>
        </td>
      </tr>
      <tr>
        <td style="width: 7.07%; vertical-align: top;">
          <div style="font-family: 'Times New Roman';">(e)</div>
        </td>
        <td style="width: 92.93%; vertical-align: top;">
          <div style="font-family: 'Times New Roman';">CUSIP Number</div>
        </td>
      </tr>
      <tr>
        <td style="width: 7.07%; vertical-align: top;">&#160;</td>
        <td style="width: 92.93%; vertical-align: top;">
          <div style="font-family: 'Times New Roman';">05370A108</div>
        </td>
      </tr>

  </table>
  <div><br>
  </div>
  <div style="clear: both; margin-top: 10pt; margin-bottom: 10pt;" id="DSPFPageBreakArea">
    <div style="page-break-after:always;" id="DSPFPageBreak">
      <hr style="margin: 4px 0px; width: 100%; border-width: 0; height: 2px; color: #000000; background-color: #000000; clear: both;" noshade="noshade"></div>
  </div>
  <div style="text-align: justify; margin-bottom: 12pt;">
    <div>
      <table style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%; text-align: left; color: #000000;" class="DSPFListTable" id="z095a92a7de85492c9284f8138218b820" cellpadding="0" cellspacing="0">

          <tr>
            <td style="width: 54pt; vertical-align: top; align: right; font-family: 'Times New Roman'; font-weight: bold;">Item&#160;3.</td>
            <td style="width: auto; vertical-align: top; text-align: justify;">
              <div style="font-family: 'Times New Roman'; font-weight: bold;">If this statement is filed pursuant to &#167;&#167;240.13d-1(b) or 240.13d-2(b) or (c), check whether the person filing is a:</div>
            </td>
          </tr>

      </table>
    </div>
  </div>
  <table style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%; border-collapse: collapse; text-align: left; color: #000000;" id="zba59ed8044e24a7cbdd56a3902237c3e" cellpadding="0" cellspacing="0">

      <tr>
        <td style="width: 6.77%; vertical-align: top;">
          <div style="margin-bottom: 6pt; font-family: 'Times New Roman';">(a)</div>
          <div>&#160;</div>
        </td>
        <td style="width: 6.77%; vertical-align: top;">
          <div style="margin-bottom: 6pt; font-family: 'Times New Roman';"><br>
            <br>
            <br>
            [ ]</div>
          <div>&#160;</div>
        </td>
        <td style="width: 86.47%; vertical-align: top;">
          <div style="text-align: justify; margin-bottom: 6pt; font-family: 'Times New Roman';"><br>
            <br>
            <br>
            Broker or dealer registered under section 15 of the Act (15 U.S.C. 78o).</div>
          <div>&#160;</div>
        </td>
      </tr>
      <tr>
        <td style="width: 6.77%; vertical-align: top;">
          <div style="margin-bottom: 6pt; font-family: 'Times New Roman';">(b)</div>
          <div>&#160;</div>
        </td>
        <td style="width: 6.77%; vertical-align: top;">
          <div style="margin-bottom: 6pt; font-family: 'Times New Roman';">[ ]</div>
          <div>&#160;</div>
        </td>
        <td style="width: 86.47%; vertical-align: top;">
          <div style="text-align: justify; margin-bottom: 6pt; font-family: 'Times New Roman';">Bank as defined in section 3(a)(6) of the Act (15 U.S.C. 78c).</div>
          <div>&#160;</div>
        </td>
      </tr>
      <tr>
        <td style="width: 6.77%; vertical-align: top;">
          <div style="margin-bottom: 6pt; font-family: 'Times New Roman';">(c)</div>
          <div>&#160;</div>
        </td>
        <td style="width: 6.77%; vertical-align: top;">
          <div style="margin-bottom: 6pt; font-family: 'Times New Roman';">[ ]</div>
          <div>&#160;</div>
        </td>
        <td style="width: 86.47%; vertical-align: top;">
          <div style="text-align: justify; margin-bottom: 6pt; font-family: 'Times New Roman';">Insurance Company as defined in Section 3(a)(19) of the Act</div>
          <div>&#160;</div>
        </td>
      </tr>
      <tr>
        <td style="width: 6.77%; vertical-align: top;">
          <div style="margin-bottom: 6pt; font-family: 'Times New Roman';">(d)</div>
          <div>&#160;</div>
        </td>
        <td style="width: 6.77%; vertical-align: top;">
          <div style="margin-bottom: 6pt; font-family: 'Times New Roman';">[ ]</div>
          <div>&#160;</div>
        </td>
        <td style="width: 86.47%; vertical-align: top;">
          <div style="text-align: justify; margin-bottom: 6pt; font-family: 'Times New Roman';">Investment company registered under section 8 of the Investment Company Act of 1940 (15 U.S.C. 80a-8).</div>
          <div>&#160;</div>
        </td>
      </tr>
      <tr>
        <td style="width: 6.77%; vertical-align: top;">
          <div style="margin-bottom: 6pt; font-family: 'Times New Roman';">(e)</div>
          <div>&#160;</div>
        </td>
        <td style="width: 6.77%; vertical-align: top;">
          <div style="margin-bottom: 6pt; font-family: 'Times New Roman';">[ ]</div>
          <div>&#160;</div>
        </td>
        <td style="width: 86.47%; vertical-align: top;">
          <div style="text-align: justify; margin-bottom: 6pt; font-family: 'Times New Roman';">An investment adviser in accordance with &#167;240.13d-1(b)(1)(ii)(E);</div>
          <div>&#160;</div>
        </td>
      </tr>
      <tr>
        <td style="width: 6.77%; vertical-align: top;">
          <div style="margin-bottom: 6pt; font-family: 'Times New Roman';">(f)</div>
          <div>&#160;</div>
        </td>
        <td style="width: 6.77%; vertical-align: top;">
          <div style="margin-bottom: 6pt; font-family: 'Times New Roman';">[ ]</div>
          <div>&#160;</div>
        </td>
        <td style="width: 86.47%; vertical-align: top;">
          <div style="text-align: justify; margin-bottom: 6pt; font-family: 'Times New Roman';">An employee benefit plan or endowment fund in accordance with &#167;240.13d-1(b)(1)(ii)(F);</div>
          <div>&#160;</div>
        </td>
      </tr>
      <tr>
        <td style="width: 6.77%; vertical-align: top;">
          <div style="margin-bottom: 6pt; font-family: 'Times New Roman';">(g)</div>
          <div>&#160;</div>
        </td>
        <td style="width: 6.77%; vertical-align: top;">
          <div style="margin-bottom: 6pt; font-family: 'Times New Roman';">[ ]</div>
          <div>&#160;</div>
        </td>
        <td style="width: 86.47%; vertical-align: top;">
          <div style="text-align: justify; margin-bottom: 6pt; font-family: 'Times New Roman';">A parent holding company or control person in accordance with &#167; 240.13d-1(b)(1)(ii)(G);</div>
          <div>&#160;</div>
        </td>
      </tr>
      <tr>
        <td style="width: 6.77%; vertical-align: top;">
          <div style="margin-bottom: 6pt; font-family: 'Times New Roman';">(h)</div>
          <div>&#160;</div>
        </td>
        <td style="width: 6.77%; vertical-align: top;">
          <div style="margin-bottom: 6pt; font-family: 'Times New Roman';">[ ]</div>
          <div>&#160;</div>
        </td>
        <td style="width: 86.47%; vertical-align: top;">
          <div style="text-align: justify; margin-bottom: 6pt; font-family: 'Times New Roman';">A savings associations as defined in Section 3(b) of the Federal Deposit Insurance Act (12 U.S.C. 1813);</div>
          <div>&#160;</div>
        </td>
      </tr>
      <tr>
        <td style="width: 6.77%; vertical-align: top;">
          <div style="margin-bottom: 6pt; font-family: 'Times New Roman';">(i)</div>
          <div>&#160;</div>
        </td>
        <td style="width: 6.77%; vertical-align: top;">
          <div style="margin-bottom: 6pt; font-family: 'Times New Roman';">[ ]</div>
          <div>&#160;</div>
        </td>
        <td style="width: 86.47%; vertical-align: top;">
          <div style="text-align: justify; margin-bottom: 6pt; font-family: 'Times New Roman';">A church plan that is excluded from the definition of an investment company under section 3(c)(14) of the Investment Company Act of 1940 (15 U.S.C. 80a-3);</div>
          <div>&#160;</div>
        </td>
      </tr>
      <tr>
        <td style="width: 6.77%; vertical-align: top;">
          <div style="margin-bottom: 6pt; font-family: 'Times New Roman';">(j)</div>
          <div>&#160;</div>
        </td>
        <td style="width: 6.77%; vertical-align: top;">
          <div style="margin-bottom: 6pt; font-family: 'Times New Roman';">[ ]</div>
          <div>&#160;</div>
        </td>
        <td style="width: 86.47%; vertical-align: top;">
          <div style="text-align: justify; margin-bottom: 6pt; font-family: 'Times New Roman';">A non-U.S. institution in accordance with &#167;240.13d&#8211;1(b)(1)(ii)(J);</div>
          <div>&#160;</div>
        </td>
      </tr>
      <tr>
        <td style="width: 6.77%; vertical-align: top;">
          <div style="margin-bottom: 6pt; font-family: 'Times New Roman';">(k)</div>
          <div>&#160;</div>
        </td>
        <td style="width: 6.77%; vertical-align: top;">
          <div style="margin-bottom: 6pt; font-family: 'Times New Roman';">[ ]</div>
          <div>&#160;</div>
        </td>
        <td style="width: 86.47%; vertical-align: top;">
          <div style="text-align: justify; margin-bottom: 6pt; font-family: 'Times New Roman';">Group, in accordance with &#167;240.13d-1(b)(1)(ii)(K).</div>
          <div>&#160;</div>
        </td>
      </tr>

  </table>
  <div><br>
  </div>
  <div style="margin-bottom: 12pt;">
    <div>
      <table style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%; text-align: left; color: #000000;" class="DSPFListTable" id="z86ec30ddbf5a4966920b0910a37859fc" cellpadding="0" cellspacing="0">

          <tr>
            <td style="width: 54pt; vertical-align: top; align: right; font-family: 'Times New Roman'; font-weight: bold;">Item&#160;4.</td>
            <td style="width: auto; vertical-align: top;">
              <div style="font-family: 'Times New Roman'; font-weight: bold;">Ownership***</div>
            </td>
          </tr>

      </table>
    </div>
  </div>
  <div style="text-indent: 36pt; margin-bottom: 12pt; font-family: 'Times New Roman';">Provide the following information regarding the aggregate number and percentage of the class of securities of the issuer identified in Item 1.</div>
  <table style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%; border-collapse: collapse; text-align: left; color: #000000;" id="zd5d52d19638045b7a9874d671e1700da" cellpadding="0" cellspacing="0">

      <tr>
        <td style="width: 6.86%; vertical-align: top;">
          <div style="font-family: 'Times New Roman';">(a)</div>
        </td>
        <td style="width: 93.14%; vertical-align: top;">
          <div style="font-family: 'Times New Roman';">Amount Beneficially Owned***</div>
        </td>
      </tr>
      <tr>
        <td style="width: 6.86%; vertical-align: top;">&#160;</td>
        <td style="width: 93.14%; vertical-align: top;">
          <div>&#160;</div>
          <div style="font-family: 'Times New Roman';">Cormorant Global Healthcare Master Fund, LP &#8211; 656,553 shares<br>
            Cormorant Global Healthcare GP, LLC &#8211; 656,553 shares</div>
          <div style="font-family: 'Times New Roman';">Cormorant Private Healthcare Fund II, LP &#8211; 1,762,115 shares</div>
          <div style="font-family: 'Times New Roman';">Cormorant Private Healthcare GP II, LLC &#8211; 1,762,115 shares</div>
          <div style="font-family: 'Times New Roman';">Cormorant Asset Management, LP &#8211; 2,464,547 shares</div>
          <div style="margin-bottom: 6pt; font-family: 'Times New Roman';">Bihua Chen &#8211; 2,464,547 shares</div>
          <div>&#160;</div>
        </td>
      </tr>
      <tr>
        <td style="width: 6.86%; vertical-align: top;">
          <div style="font-family: 'Times New Roman';">(b)</div>
        </td>
        <td style="width: 93.14%; vertical-align: top;">
          <div style="font-family: 'Times New Roman';">Percent of Class</div>
        </td>
      </tr>
      <tr>
        <td style="width: 6.86%; vertical-align: top;">&#160;</td>
        <td style="width: 93.14%; vertical-align: top;">
          <div>&#160;</div>
          <div style="font-family: 'Times New Roman';">Cormorant Global Healthcare Master Fund, LP &#8211; 1.75%<br>
            Cormorant Global Healthcare GP, LLC &#8211; 1.75%</div>
          <div style="font-family: 'Times New Roman';">Cormorant Private Healthcare Fund II, LP &#8211; 4.70%</div>
          <div style="font-family: 'Times New Roman';">Cormorant Private Healthcare GP II, LLC &#8211; 4.70%</div>
          <div style="font-family: 'Times New Roman';">Cormorant Asset Management, LP &#8211; 6.57%<br>
            Bihua Chen &#8211; 6.57%</div>
        </td>
      </tr>

  </table>
  <div><br>
  </div>
  <table style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%; border-collapse: collapse; text-align: left; color: #000000;" id="z3608fd5a13a04fb6a3bb0ffb9ef6e7ff" cellpadding="0" cellspacing="0">

      <tr>
        <td style="width: 6.86%; vertical-align: top;">
          <div style="font-family: 'Times New Roman';">(c)</div>
        </td>
        <td colspan="2" style="width: 93.14%; vertical-align: top;">
          <div style="font-family: 'Times New Roman';">Number of shares as to which such person has:</div>
          <div>&#160;</div>
        </td>
      </tr>
      <tr>
        <td style="width: 6.86%; vertical-align: top;">&#160;</td>
        <td style="width: 6.86%; vertical-align: top;">
          <div style="font-family: 'Times New Roman';">(i)</div>
        </td>
        <td style="width: 86.28%; vertical-align: top;">
          <div style="font-family: 'Times New Roman';">sole power to vote or to direct the vote</div>
        </td>
      </tr>
      <tr>
        <td style="width: 6.86%; vertical-align: top;">&#160;</td>
        <td style="width: 6.86%; vertical-align: top;">&#160;</td>
        <td style="width: 86.28%; vertical-align: top;">
          <div style="font-family: 'Times New Roman';"><br>
            Cormorant Global Healthcare Master Fund, LP - 0 shares<br>
            Cormorant Global Healthcare GP, LLC - 0 shares</div>
          <div style="font-family: 'Times New Roman';">Cormorant Private Healthcare Fund II, LP &#8211; 0 shares</div>
          <div style="font-family: 'Times New Roman';">Cormorant Private Healthcare GP II, LLC &#8211; 0 shares</div>
          <div style="font-family: 'Times New Roman';">Cormorant Asset Management, LP - 0 shares</div>
          <div style="font-family: 'Times New Roman';">Bihua Chen - 0 shares</div>
          <div>&#160;</div>
        </td>
      </tr>
      <tr>
        <td style="width: 6.86%; vertical-align: top;">&#160;</td>
        <td style="width: 6.86%; vertical-align: top;">
          <div style="font-family: 'Times New Roman';">(ii)</div>
        </td>
        <td style="width: 86.28%; vertical-align: top;">
          <div style="font-family: 'Times New Roman';">shared power to vote or to direct the vote</div>
        </td>
      </tr>
      <tr>
        <td style="width: 6.86%; vertical-align: top;">&#160;</td>
        <td style="width: 6.86%; vertical-align: top;">&#160;</td>
        <td style="width: 86.28%; vertical-align: top;">
          <div>&#160;</div>
          <div style="font-family: 'Times New Roman';">Cormorant Global Healthcare Master Fund, LP &#8211; 656,553 shares<br>
            Cormorant Global Healthcare GP, LLC &#8211; 656,553 shares</div>
          <div style="font-family: 'Times New Roman';">Cormorant Private Healthcare Fund II, LP &#8211; 1,762,115 shares</div>
          <div style="font-family: 'Times New Roman';">Cormorant Private Healthcare GP II, LLC &#8211; 1,762,115 shares</div>
          <div style="font-family: 'Times New Roman';">Cormorant Asset Management, LP &#8211; 2,464,547 shares</div>
          <div style="margin-bottom: 6pt; font-family: 'Times New Roman';">Bihua Chen &#8211; 2,464,547 shares</div>
          <div>&#160;</div>
        </td>
      </tr>
      <tr>
        <td style="width: 6.86%; vertical-align: top;">&#160;</td>
        <td style="width: 6.86%; vertical-align: top;">
          <div style="font-family: 'Times New Roman';">(iii)</div>
        </td>
        <td style="width: 86.28%; vertical-align: top;">
          <div style="font-family: 'Times New Roman';">sole power to dispose or to direct the disposition of</div>
        </td>
      </tr>
      <tr>
        <td style="width: 6.86%; vertical-align: top;">&#160;</td>
        <td style="width: 6.86%; vertical-align: top;">&#160;</td>
        <td style="width: 86.28%; vertical-align: top;">
          <div style="font-family: 'Times New Roman';"><br>
            Cormorant Global Healthcare Master Fund, LP - 0 shares<br>
            Cormorant Global Healthcare GP, LLC - 0 shares</div>
          <div style="font-family: 'Times New Roman';">Cormorant Private Healthcare Fund II, LP &#8211; 0 shares</div>
          <div style="font-family: 'Times New Roman';">Cormorant Private Healthcare GP II, LLC &#8211; 0 shares</div>
          <div style="font-family: 'Times New Roman';">Cormorant Asset Management, LP - 0 shares</div>
          <div style="font-family: 'Times New Roman';">Bihua Chen - 0 shares</div>
          <div>&#160;</div>
        </td>
      </tr>
      <tr>
        <td style="width: 6.86%; vertical-align: top;">&#160;</td>
        <td style="width: 6.86%; vertical-align: top;">
          <div style="font-family: 'Times New Roman';">(iv)</div>
        </td>
        <td style="width: 86.28%; vertical-align: top;">
          <div style="font-family: 'Times New Roman';">shared power to dispose or to direct the disposition of</div>
        </td>
      </tr>
      <tr>
        <td style="width: 6.86%; vertical-align: top;">&#160;</td>
        <td style="width: 6.86%; vertical-align: top;">&#160;</td>
        <td style="width: 86.28%; vertical-align: top;">
          <div>&#160;</div>
          <div style="font-family: 'Times New Roman';">Cormorant Global Healthcare Master Fund, LP &#8211; 656,553 shares<br>
            Cormorant Global Healthcare GP, LLC &#8211; 656,553 shares</div>
          <div style="font-family: 'Times New Roman';">Cormorant Private Healthcare Fund II, LP &#8211; 1,762,115 shares</div>
          <div style="font-family: 'Times New Roman';">Cormorant Private Healthcare GP II, LLC &#8211; 1,762,115 shares</div>
          <div style="font-family: 'Times New Roman';">Cormorant Asset Management, LP &#8211; 2,464,547 shares</div>
          <div style="margin-bottom: 6pt; font-family: 'Times New Roman';">Bihua Chen &#8211; 2,464,547 shares</div>
          <div>&#160;</div>
        </td>
      </tr>

  </table>
  <div style="margin-top: 5pt; margin-bottom: 5pt;"><br>
  </div>
  <div style="text-align: justify; margin-left: 36pt; margin-top: 5pt; margin-bottom: 5pt; font-family: 'Times New Roman';">*** Shares reported herein for Cormorant Asset Management, LP represent shares which are beneficially by Cormorant Global Healthcare
    Master Fund, LP (the &#8220;Master Fund&#8221;) and Cormorant Private Healthcare Fund&#160;II, LP (&#8220;Fund II&#8221;), as reported herein, and a managed account (the &#8220;Account&#8221;).&#160; Cormorant Global Healthcare GP, LLC, and Cormorant Private Healthcare GP II, LLC serve as the
    general partners of the Master Fund and Fund II, respectively. Cormorant Asset Management, LP serves as the investment manager to the Master Fund, Fund II and the Account.&#160; Bihua Chen serves as the managing member of Cormorant Global Healthcare GP,
    LLC, Cormorant Private Healthcare GP II, LLC and the general partner of Cormorant Asset Management, LP.&#160; Each of the Reporting Persons disclaims beneficial ownership of the shares reported herein except to the extent of its or his pecuniary interest
    therein.</div>
  <div style="text-align: justify; margin-left: 36pt; margin-top: 5pt; margin-bottom: 5pt; font-family: 'Times New Roman';">The percentages reported herein with respect to the Reporting Persons&#8217; holdings are calculated based upon there being 37,526,631
    shares of Common Stock outstanding as of October 20, 2020, as reported in the Issuer's Form 10-Q for the quarter ended September 30, 2020, as filed with the Securities and Exchange Commission on November 10, 2020.</div>
  <div style="margin-top: 5pt; margin-bottom: 5pt;"><br>
  </div>
  <div style="margin-bottom: 12pt;">
    <div>
      <table style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%; text-align: left; color: #000000;" class="DSPFListTable" id="z90d9c11d18824b19897562ccc1914511" cellpadding="0" cellspacing="0">

          <tr>
            <td style="width: 54pt; vertical-align: top; align: right;"><font style="font-family: 'Times New Roman'; font-weight: bold;">Item&#160;5</font><font style="font-family: 'Times New Roman'; font-weight: bold;">.</font></td>
            <td style="width: auto; vertical-align: top;">
              <div style="font-family: 'Times New Roman'; font-weight: bold;">Ownership of Five Percent or Less of a Class</div>
            </td>
          </tr>

      </table>
    </div>
  </div>
  <div style="text-align: justify; text-indent: 54pt; margin-bottom: 12pt; font-family: 'Times New Roman';">If this statement is being filed to report the fact that as of the date hereof the reporting person has ceased to be the beneficial owner of more
    than five percent of the class of securities, check the following [&#160; ].</div>
  <div style="margin-bottom: 12pt;">
    <div>
      <table style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%; text-align: left; color: #000000;" class="DSPFListTable" id="z376e1b6824b6474fa70c2372a3a11e8b" cellpadding="0" cellspacing="0">

          <tr>
            <td style="width: 54pt; vertical-align: top; align: right;"><font style="font-family: 'Times New Roman'; font-weight: bold;">Item&#160;6</font><font style="font-family: 'Times New Roman'; font-weight: bold;">.</font></td>
            <td style="width: auto; vertical-align: top;">
              <div style="font-family: 'Times New Roman'; font-weight: bold;">Ownership of More than Five Percent on Behalf of Another Person</div>
            </td>
          </tr>

      </table>
    </div>
  </div>
  <div style="text-indent: 54pt; margin-bottom: 12pt; font-family: 'Times New Roman';">Not applicable.</div>
  <div style="margin-bottom: 12pt;">
    <div>
      <table style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%; text-align: left; color: #000000;" class="DSPFListTable" id="z27984f845c834bcaa9502b7187a0ce49" cellpadding="0" cellspacing="0">

          <tr>
            <td style="width: 54pt; vertical-align: top; align: right;"><font style="font-family: 'Times New Roman'; font-weight: bold;">Item&#160;7</font><font style="font-family: 'Times New Roman'; font-weight: bold;">.</font></td>
            <td style="width: auto; vertical-align: top;">
              <div style="font-family: 'Times New Roman'; font-weight: bold;">Identification and Classification of the Subsidiary Which Acquired the Security Being Reported on By the Parent Holding Company</div>
            </td>
          </tr>

      </table>
    </div>
  </div>
  <div style="text-indent: 54pt; margin-bottom: 12pt; font-family: 'Times New Roman';">Not applicable.</div>
  <div style="margin-bottom: 12pt;">
    <div>
      <table style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%; text-align: left; color: #000000;" class="DSPFListTable" id="z459c05f66bf44baeb3853e70abf4c203" cellpadding="0" cellspacing="0">

          <tr>
            <td style="width: 54pt; vertical-align: top; align: right; font-family: 'Times New Roman'; font-weight: bold;">Item&#160;8.</td>
            <td style="width: auto; vertical-align: top;">
              <div style="font-family: 'Times New Roman'; font-weight: bold;">Identification and Classification of Members of the Group</div>
            </td>
          </tr>

      </table>
    </div>
  </div>
  <div style="text-indent: 54pt; margin-bottom: 12pt; font-family: 'Times New Roman';">Not applicable.</div>
  <div style="margin-bottom: 12pt;">
    <div>
      <table style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%; text-align: left; color: #000000;" class="DSPFListTable" id="z78d137f7e18c4a3d8eb919e938c6269f" cellpadding="0" cellspacing="0">

          <tr>
            <td style="width: 54pt; vertical-align: top; align: right; font-family: 'Times New Roman'; font-weight: bold;">Item&#160;9.</td>
            <td style="width: auto; vertical-align: top;">
              <div style="font-family: 'Times New Roman'; font-weight: bold;">Notice of Dissolution of Group</div>
            </td>
          </tr>

      </table>
    </div>
  </div>
  <div style="text-indent: 54pt; margin-bottom: 12pt; font-family: 'Times New Roman';">Not applicable.</div>
  <div style="margin-bottom: 12pt;">
    <div>
      <table style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%; text-align: left; color: #000000;" class="DSPFListTable" id="z1a8b90ef695d484d8e83f8e095759e5c" cellpadding="0" cellspacing="0">

          <tr>
            <td style="width: 54pt; vertical-align: top; align: right; font-family: 'Times New Roman'; font-weight: bold;">Item&#160;10.</td>
            <td style="width: auto; vertical-align: top;">
              <div style="font-family: 'Times New Roman'; font-weight: bold;">Certification</div>
            </td>
          </tr>

      </table>
    </div>
  </div>
  <div style="text-align: justify; text-indent: 36pt; font-family: 'Times New Roman';">By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were not acquired and are not held for the purpose of or with
    the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect.</div>
  <div><br>
  </div>
  <div style="text-align: justify; font-family: 'Times New Roman'; font-weight: bold;">Exhibits&#160; &#160;&#160; Exhibit</div>
  <div><br>
  </div>
  <div><br>
  </div>
  <div style="margin-bottom: 12pt;"><font style="font-family: 'Times New Roman'; font-weight: bold;">99.1</font><font style="text-indent: 0px; font-size: 5.14pt;" id="TRGRRTFtoHTMLTab">&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;</font><font style="font-family: 'Times New Roman';">&#160; &#160; &#160;
      Joint Filing Agreement by and among the Reporting Persons</font>, incorporated by reference to Exhibit 99.1 to Schedule 13G filed by the Reporting Persons with the Securities and Exchange Commission on June 26, 2020.</div>
  <div style="clear: both; margin-top: 10pt; margin-bottom: 10pt;" id="DSPFPageBreakArea">
    <div style="page-break-after:always;" id="DSPFPageBreak">
      <hr style="margin: 4px 0px; width: 100%; border-width: 0; height: 2px; color: #000000; background-color: #000000; clear: both;" noshade="noshade"></div>
  </div>
  <div style="margin-bottom: 12pt; font-family: 'Times New Roman'; font-weight: bold;">SIGNATURE</div>
  <div style="text-align: justify; text-indent: 36pt; margin-bottom: 12pt; font-family: 'Times New Roman';">After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this Statement is true, complete
    and correct.</div>
  <div style="margin-bottom: 12pt; font-family: 'Times New Roman';">February 16, 2021<br>
  </div>
  <div><br>
  </div>
  <div><br>
  </div>
  <div style="margin-left: 234pt; font-family: 'Times New Roman';">CORMORANT GLOBAL HEALTHCARE MASTER FUND, LP</div>
  <div><br>
  </div>
  <div style="text-indent: 234pt; font-family: 'Times New Roman';">By: Cormorant Global Healthcare GP, LLC
    <div>its General Partner</div>
  </div>
  <div><br>
  </div>
  <div style="text-indent: 234pt; font-family: 'Times New Roman';">By: <u>/s/ Bihua Chen</u></div>
  <div style="text-indent: 234pt; font-family: 'Times New Roman';">Bihua Chen, Managing Member</div>
  <div><br>
  </div>
  <div style="margin-left: 234pt; font-family: 'Times New Roman';">CORMORANT GLOBAL HEALTHCARE GP, LLC</div>
  <div><br>
  </div>
  <div style="text-indent: 234pt; font-family: 'Times New Roman';">By: <u>/s/ Bihua Chen</u></div>
  <div style="text-indent: 234pt; font-family: 'Times New Roman';">Bihua Chen, Managing Member</div>
  <div><br>
  </div>
  <div style="margin-left: 234pt; font-family: 'Times New Roman';">CORMORANT PRIVATE HEALTHCARE FUND II, LP</div>
  <div style="text-indent: 234pt; font-family: 'Times New Roman';">By: Cormorant Global Healthcare GP II, LLC</div>
  <div style="text-indent: 234pt; font-family: 'Times New Roman';">its General Partner</div>
  <div><br>
  </div>
  <div style="text-indent: 234pt; font-family: 'Times New Roman';">By: <u>/s/ Bihua Chen</u></div>
  <div style="text-indent: 234pt; font-family: 'Times New Roman';">Bihua Chen, Managing Member</div>
  <div><br>
  </div>
  <div style="margin-left: 234pt; font-family: 'Times New Roman';">CORMORANT PRIVATE HEALTHCARE GP&#160;II, LLC</div>
  <div><br>
  </div>
  <div style="text-indent: 234pt; font-family: 'Times New Roman';">By: <u>/s/ Bihua Chen</u></div>
  <div style="text-indent: 234pt; font-family: 'Times New Roman';">Bihua Chen, Managing Member</div>
  <div><br>
  </div>
  <div style="margin-left: 234pt; font-family: 'Times New Roman';">CORMORANT ASSET MANAGEMENT, LP</div>
  <div style="text-indent: 234pt; font-family: 'Times New Roman';">By: Cormorant Asset Management GP, LLC</div>
  <div style="text-indent: 234pt; font-family: 'Times New Roman';">its General Partner</div>
  <div><br>
  </div>
  <div style="text-indent: 234pt; font-family: 'Times New Roman';">By: <u>/s/ Bihua Chen</u></div>
  <div style="text-indent: 234pt; font-family: 'Times New Roman';">Bihua Chen, Managing Member</div>
  <div><br>
  </div>
  <div style="text-indent: 234pt; font-family: 'Times New Roman';"><u>/s/ Bihua Chen</u></div>
  <div style="text-indent: 234pt; font-family: 'Times New Roman';">Bihua Chen</div>
  <br>
</body>
</html>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
