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Insider Trading Arrangements
 3 Months Ended 12 Months Ended
Dec. 31, 2024
shares
Dec. 31, 2024
shares
Trading Arrangements, by Individual    
Material Terms of Trading Arrangement  
From time to time, our officers (as defined in Rule 16a–1(f)) and directors may enter into Rule 10b5-1 or non-Rule 10b5-1 trading arrangements (as each such term is defined in Item 408 of Regulation S-K). During the three months ended December 31, 2024, our officers or directors took the following actions with respect to such trading arrangements:
ActionDateTrading ArrangementTotal Shares to be SoldExpiration Date
Rule 10b5-1*Non-Rule 10b5-1**
Troy Wilson (Ph.D., J.D.)(1)
Adopt12/4/2024X
190,106(2)
3/31/2026
Arthur A. Levin (Ph.D.)
Adopt10/17/2024X309,09612/31/2025
____________________
* Intended to satisfy the affirmative defense of Rule 10b5-1(c)
** Not intended to satisfy the affirmative defense of Rule 10b5-1(c)

(1)This plan was adopted by Mr. Wilson and certain irrevocable trusts for the benefit of Mr. Wilson's family members, none of which Mr. Wilson controls.
(2)Represents the aggregate maximum number of shares to be sold under this plan by Mr. Wilson and all signatories to this plan. The maximum number of shares to be sold under this plan by Mr. Wilson is 59,000.
Non-Rule 10b5-1 Arrangement Adopted false  
Rule 10b5-1 Arrangement Terminated false  
Non-Rule 10b5-1 Arrangement Terminated false  
Troy Wilson [Member]    
Trading Arrangements, by Individual    
Name Troy Wilson  
Title Ph.D., J.D.  
Rule 10b5-1 Arrangement Adopted true  
Adoption Date 12/4/2024  
Expiration Date 3/31/2026  
Arrangement Duration 482 days  
Aggregate Available 190,106 190,106
Arthur A. Levin [Member]    
Trading Arrangements, by Individual    
Name Arthur A. Levin  
Title Ph.D.  
Rule 10b5-1 Arrangement Adopted true  
Adoption Date 10/17/2024  
Expiration Date 12/31/2025  
Arrangement Duration 440 days  
Aggregate Available 309,096 309,096