XML 168 R56.htm IDEA: XBRL DOCUMENT v3.25.0.1
Income Taxes - Additional Information (Details) - USD ($)
$ in Thousands
 12 Months Ended
Dec. 31, 2024
Dec. 31, 2023
Dec. 31, 2022
Income Taxes Disclosure [Line Items]      
Provision for income taxes $ 0 $ 0 $ 0
Increase in the valuation allowance 98,800 61,300  
Unrecognized tax benefits that would impact effective tax rate 0    
Accruals for interest or penalties 0 $ 0  
Federal      
Income Taxes Disclosure [Line Items]      
Net operating loss (NOL) carryforwards 249,400    
Federal and state tax credit carryforwards 13,300    
Federal | Orphan Drug Tax Credits      
Income Taxes Disclosure [Line Items]      
Federal and state tax credit carryforwards 58,000    
State      
Income Taxes Disclosure [Line Items]      
Net operating loss (NOL) carryforwards 439,300    
Federal and state tax credit carryforwards $ 15,800