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Income Taxes - Schedule of Reconciliation of Income Taxes Computed by Applying Statutory Federal Income Tax Rate (Details) - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2024
Dec. 31, 2023
Dec. 31, 2022
Income Tax Disclosure [Abstract]      
Income tax expense (benefit) at statutory rates $ (67,683) $ (44,566) $ (36,539)
State income tax, net of federal benefit (8,170) (5,882) (11,821)
Permanent items 66 51 1
Reserve for uncertain tax positions 10,572 5,993 2,583
Research and development tax credits (42,279) (24,054) (9,983)
Valuation allowance 98,813 61,332 54,093
Stock-based compensation (15,264) 3,331 492
Section 162(m) disallowance 20,604 291 1,077
Rate adjustment 2,766 2,526 (5)
Other 575 978 102
Income tax expense (benefit) $ 0 $ 0 $ 0