<SEC-DOCUMENT>0001968582-25-001010.txt : 20251027
<SEC-HEADER>0001968582-25-001010.hdr.sgml : 20251027
<ACCEPTANCE-DATETIME>20251027160659
ACCESSION NUMBER:		0001968582-25-001010
CONFORMED SUBMISSION TYPE:	144
PUBLIC DOCUMENT COUNT:		1
FILED AS OF DATE:		20251027
DATE AS OF CHANGE:		20251027

SUBJECT COMPANY:	

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Nuvalent, Inc.
		CENTRAL INDEX KEY:			0001861560
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		ORGANIZATION NAME:           	03 Life Sciences
		EIN:				000000000
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		144
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	001-40671
		FILM NUMBER:		251419945

	BUSINESS ADDRESS:	
		STREET 1:		ONE BROADWAY, 14TH FLOOR
		CITY:			CAMBRIDGE
		STATE:			MA
		ZIP:			02142
		BUSINESS PHONE:		508-446-2272

	MAIL ADDRESS:	
		STREET 1:		ONE BROADWAY, 14TH FLOOR
		CITY:			CAMBRIDGE
		STATE:			MA
		ZIP:			02142

REPORTING-OWNER:	

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Shair Matthew
		CENTRAL INDEX KEY:			0001862123
		ORGANIZATION NAME:           	

	FILING VALUES:
		FORM TYPE:		144

	MAIL ADDRESS:	
		STREET 1:		ONE BROADWAY, 14TH FLOOR
		CITY:			CAMBRIDGE
		STATE:			MA
		ZIP:			02142
</SEC-HEADER>
<DOCUMENT>
<TYPE>144
<SEQUENCE>1
<FILENAME>primary_doc.xml
<TEXT>
<XML>
<?xml version="1.0" encoding="UTF-8"?><edgarSubmission xmlns="http://www.sec.gov/edgar/ownership" xmlns:com="http://www.sec.gov/edgar/common">
  <!-- Generated by Workiva -->
  <headerData>
    <submissionType>144</submissionType>
    <filerInfo>
      <filer>
        <filerCredentials>
          <cik>0001862123</cik>
          <ccc>XXXXXXXX</ccc>
        </filerCredentials>
      </filer>
      <liveTestFlag>LIVE</liveTestFlag>



    </filerInfo>
  </headerData>
  <formData>
    <issuerInfo>
      <issuerCik>0001861560</issuerCik>
      <issuerName>Nuvalent Inc</issuerName>
      <secFileNumber>001-40671</secFileNumber>
      <issuerAddress>
        <com:street1>One Broadway, 14th Floor</com:street1>
        <com:city>Cambridge</com:city>
        <com:stateOrCountry>MA</com:stateOrCountry>
        <com:zipCode>02142</com:zipCode>
      </issuerAddress>
      <issuerContactPhone>857-357-7000</issuerContactPhone>
      <nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>Matthew Shair</nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
      <relationshipsToIssuer>
        <relationshipToIssuer>Director</relationshipToIssuer>
      </relationshipsToIssuer>
    </issuerInfo>
    <securitiesInformation>
      <securitiesClassTitle>Class A Common</securitiesClassTitle>
      <brokerOrMarketmakerDetails>
        <name>J.P. Morgan Securities LLC</name>
        <address>
          <com:street1>270 Park Avenue</com:street1>
          <com:street2>10th Floor</com:street2>
          <com:city>New York</com:city>
          <com:stateOrCountry>NY</com:stateOrCountry>
          <com:zipCode>10017</com:zipCode>
        </address>
      </brokerOrMarketmakerDetails>
      <noOfUnitsSold>18150</noOfUnitsSold>
      <aggregateMarketValue>1815000</aggregateMarketValue>
      <noOfUnitsOutstanding>66669583</noOfUnitsOutstanding>
      <approxSaleDate>10/27/2025</approxSaleDate>
      <securitiesExchangeName>Nasdaq</securitiesExchangeName>
    </securitiesInformation>
    <securitiesToBeSold>
      <securitiesClassTitle>Class A Common</securitiesClassTitle>
      <acquiredDate>07/13/2021</acquiredDate>
      <natureOfAcquisitionTransaction>Grant</natureOfAcquisitionTransaction>
      <nameOfPersonfromWhomAcquired>Matthew Shair, who acquired the shares from issuer on 02/17/17, transferred to trust on 7/13/21</nameOfPersonfromWhomAcquired>
      <isGiftTransaction>N</isGiftTransaction>
      <amountOfSecuritiesAcquired>18150</amountOfSecuritiesAcquired>
      <paymentDate>07/13/2021</paymentDate>
      <natureOfPayment>Transfer</natureOfPayment>
    </securitiesToBeSold>
    <nothingToReportFlagOnSecuritiesSoldInPast3Months>Y</nothingToReportFlagOnSecuritiesSoldInPast3Months>
    <remarks>The shares represented on this filing are shares to be sold in the next 3 months by the Matthew Shair 2021 Irrevocable Trust</remarks>
    <noticeSignature>
      <noticeDate>10/27/2025</noticeDate>
      <planAdoptionDates>
        <planAdoptionDate>11/20/2024</planAdoptionDate>
      </planAdoptionDates>
      <signature>/s/ J.P. Morgan Securities LLC as agent and attorney-in-fact for Matthew Shair</signature>
    </noticeSignature>
  </formData>
</edgarSubmission>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
