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Income Taxes - Schedule of Deferred Tax Assets and Liabilities (Detail) - USD ($) $ in Thousands | Dec. 31, 2025 | Dec. 31, 2024
--- | --- | ---
Deferred Tax Assets, Gross [Abstract] |  |
Net operating loss carryforwards | $ 139,120 | $ 56,677
Capitalized research and development | 103,127 | 94,002
Research and development tax credit carryforwards | 82,361 | 52,117
Change in fair value of related party revenue share liability | 19,284 | 4,785
Stock-based compensation | 14,225 | 9,705
Other | 4,648 | 2,714
Total gross deferred tax assets | 362,765 | 220,000
Valuation allowance | (362,495) | (220,000)
Total net deferred tax assets | 270 | 0
Deferred tax liabilities |  |
Other | (270) | 0
Total gross deferred tax liabilities | 270 | 0
Net deferred tax assets | $ 0 | $ 0

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