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Accrued Expenses - Schedule of Accrued Expenses and Other Current Liabilities (Detail) - USD ($)
$ in Thousands
Dec. 31, 2025
Dec. 31, 2024
Accrued Liabilities, Current [Abstract]    
Accrued clinical and other research and development $ 30,235 $ 25,555
Accrued manufacturing 10,976 11,511
Accrued employee compensation and benefits 16,935 10,452
Accrued other and other current liabilities 2,867 1,277
Total accrued expenses and other current liabilities $ 61,013 $ 48,795