XML 17 R5.htm IDEA: XBRL DOCUMENT v3.25.1
UNAUDITED INTERIM CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS - USD ($)
$ in Thousands
 3 Months Ended
Mar. 31, 2025
Mar. 31, 2024
CASH FLOWS (USED IN)/PROVIDED BY OPERATING ACTIVITIES    
Loss before tax $ (99,130) $ (59,788)
Adjustments for:    
Finance income (12,056) (13,870)
Finance costs 5,061 5,475
Provision for inventory reserve (3,798) 1,757
Loss on asset impairment 970 0
Depreciation of property, plant and equipment 2,284 2,796
Loss on disposal of property, plant and equipment 53 2
Amortization of intangible assets 128 885
Depreciation of right-of-use assets 2,787 2,041
Fair value gains on financial assets measured at fair value through profit or loss 0 (449)
Foreign currency exchange loss/(gain), net 55,192 (49,056)
Equity-settled share-based compensation expense 15,946 18,703
Deferred government grant (134) (157)
Cash flows provided by (used in) operations before changes in working capital (32,697) (91,661)
Decrease in trade receivables 5,918 96,734
Increase in prepayments, other receivables and other assets (48,586) (16,266)
Decrease in other non-current assets 473 77
Increase in collaboration inventories (3,232) (4,470)
Increase in trade payables [1] 19,510 22,796
(Decrease)/increase in other payables and accruals [1] (38,635) 7,380
Increase/(decrease) in other non-current liabilities 0 (25)
Decrease in contract liabilities, net (9,037) (12,181)
Cash (used in)/provided by operations (106,286) 2,384
Interest income received 14,957 13,479
Income tax (paid)/received (11,926) 71
Interest on lease payments (499) (416)
Net cash (used in)/provided by operating activities (103,754) 15,518
CASH FLOWS PROVIDED BY/(USED IN) INVESTING ACTIVITIES    
Purchase of property, plant and equipment (2,002) (6,243)
Prepayment to collaborator for collaboration assets (15,358) (16,541)
Purchase of financial assets measured at fair value through profit or loss 0 (150,308)
Cash receipts of investment income 0 663
Proceeds from disposal of property, plant and equipment 0 (2)
Addition in time deposits (100,000) (721,990)
Decrease in time deposits 374,000 498,273
Net cash provided by/(used in) investing activities 256,640 (396,148)
CASH FLOWS PROVIDED BY FINANCING ACTIVITIES    
Proceeds from exercise of share options 1,444 1,589
Principal portion of lease payments (777) (758)
Net cash provided by financing activities 667 831
NET INCREASE (DECREASE) IN CASH AND CASH EQUIVALENTS 153,553 (379,799)
Effect of foreign exchange rate changes, net 1,400 (343)
Cash and cash equivalents at beginning of year 286,749 1,277,713
CASH AND CASH EQUIVALENTS AT END OF PERIOD 441,702 897,571
ANALYSIS OF BALANCES OF CASH AND CASH EQUIVALENTS    
Cash and bank balances 1,005,450 1,156,674
Less: Pledged deposits 70 359
Time deposits 563,678 258,744
Cash and cash equivalents as stated in the statement of financial position 441,702 897,571
Cash and cash equivalents as stated in the statement of cash flows $ 441,702 $ 897,571
[1] Certain prior year amounts have been reclassified between increase in trade payables and (decrease)/increase in other payables and accruals for comparative purposes