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    <link:label id="lab_us-gaap_FairValueDisclosureItemAmountsDomain_9c7b7aad-0813-4e55-8cb7-807cdf3d45a8_terseLabel_en-US" xlink:label="lab_us-gaap_FairValueDisclosureItemAmountsDomain" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Fair Value Measurement [Domain]</link:label>
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    <link:label id="lab_us-gaap_Depreciation_88d7b5dd-ce2b-4c4f-a229-3b58eaae0147_terseLabel_en-US" xlink:label="lab_us-gaap_Depreciation" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Depreciation of premises and equipment</link:label>
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    <link:label id="lab_slm_ThirdPartyBrokerFeesPaid_eab9a0ec-300a-485b-a217-c81686a4dab4_terseLabel_en-US" xlink:label="lab_slm_ThirdPartyBrokerFeesPaid" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Third party broker fees paid</link:label>
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    <link:label id="lab_slm_FinancingReceivableAllowanceForCreditLossWriteoffAfterRecoveryOriginatedInCurrentFiscalYear_66a77e2e-e01a-411c-9c60-35999a65c3c2_negatedTerseLabel_en-US" xlink:label="lab_slm_FinancingReceivableAllowanceForCreditLossWriteoffAfterRecoveryOriginatedInCurrentFiscalYear" xlink:role="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Current period net charge-offs, Year 1</link:label>
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    <link:label id="lab_us-gaap_IncomeTaxesPaid_02f49c7b-ae55-4615-9325-bcb85dc75165_terseLabel_en-US" xlink:label="lab_us-gaap_IncomeTaxesPaid" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Income taxes paid</link:label>
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    <link:label id="lab_us-gaap_EquityComponentDomain_label_en-US" xlink:label="lab_us-gaap_EquityComponentDomain" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Equity Component [Domain]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquityComponentDomain" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_EquityComponentDomain"/>
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    <link:label id="lab_slm_LoansOriginatedInFiscalYearBeforeLatestFiscalYear_1802190c-9d6f-4cbe-a901-dda1d6c20338_terseLabel_en-US" xlink:label="lab_slm_LoansOriginatedInFiscalYearBeforeLatestFiscalYear" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Total Private Education Loans, Year 2</link:label>
    <link:label id="lab_slm_LoansOriginatedInFiscalYearBeforeLatestFiscalYear_label_en-US" xlink:label="lab_slm_LoansOriginatedInFiscalYearBeforeLatestFiscalYear" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Loans, Originated In Fiscal Year Before Latest Fiscal Year</link:label>
    <link:label id="lab_slm_LoansOriginatedInFiscalYearBeforeLatestFiscalYear_documentation_en-US" xlink:label="lab_slm_LoansOriginatedInFiscalYearBeforeLatestFiscalYear" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Loans, Originated In Fiscal Year Before Latest Fiscal Year</link:label>
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    <link:label id="lab_us-gaap_SecuredDebtMember_52792299-8a2a-4ffb-b7b3-039dd5bc6a91_terseLabel_en-US" xlink:label="lab_us-gaap_SecuredDebtMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Secured Borrowings</link:label>
    <link:label id="lab_us-gaap_SecuredDebtMember_label_en-US" xlink:label="lab_us-gaap_SecuredDebtMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Secured Debt [Member]</link:label>
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    <link:label id="lab_slm_FinancingReceivableExcludingAccruedInterestBeforeAllowanceForCreditLossesLoanModificationsAmortizedCost_aa77e615-e76f-4cf3-b0a6-74827e5a76c7_terseLabel_en-US" xlink:label="lab_slm_FinancingReceivableExcludingAccruedInterestBeforeAllowanceForCreditLossesLoanModificationsAmortizedCost" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Loans</link:label>
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    <link:label id="lab_us-gaap_AvailableForSaleSecuritiesDebtSecurities_714a0230-36e9-48c3-a411-250967a8564a_terseLabel_en-US" xlink:label="lab_us-gaap_AvailableForSaleSecuritiesDebtSecurities" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Available-for-sale investments at fair value (cost of $2,487,749 and $2,554,332, respectively)</link:label>
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    <link:label id="lab_slm_PercentageOfLoansInRepaymentOriginatedInFiscalYearBeforeLatestFiscalYear_8d8c7b6c-3706-4c36-9da0-861e3db534cd_terseLabel_en-US" xlink:label="lab_slm_PercentageOfLoansInRepaymentOriginatedInFiscalYearBeforeLatestFiscalYear" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Percentage of Private Education Loans in repayment, Year 2</link:label>
    <link:label id="lab_slm_PercentageOfLoansInRepaymentOriginatedInFiscalYearBeforeLatestFiscalYear_label_en-US" xlink:label="lab_slm_PercentageOfLoansInRepaymentOriginatedInFiscalYearBeforeLatestFiscalYear" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Percentage Of Loans In Repayment, Originated In Fiscal Year Before Latest Fiscal Year</link:label>
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    <link:label id="lab_us-gaap_FinancingReceivableExcludingAccruedInterestOriginatedMoreThanFiveYearsBeforeCurrentFiscalYear_cf0c8a33-97e3-4080-b284-d20293944054_terseLabel_en-US" xlink:label="lab_us-gaap_FinancingReceivableExcludingAccruedInterestOriginatedMoreThanFiveYearsBeforeCurrentFiscalYear" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">After Year 5</link:label>
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    <link:label id="lab_us-gaap_SupplementalCashFlowInformationAbstract_1aa6ab9b-c06d-4db2-b96c-1d2b44aa0c08_terseLabel_en-US" xlink:label="lab_us-gaap_SupplementalCashFlowInformationAbstract" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Cash disbursements made for:</link:label>
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    <link:label id="lab_slm_AccruedInterestReceivableFairValueDisclosureDifference_a2691802-4784-449d-9858-7b113c570717_terseLabel_en-US" xlink:label="lab_slm_AccruedInterestReceivableFairValueDisclosureDifference" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Accrued interest receivable, difference</link:label>
    <link:label id="lab_slm_AccruedInterestReceivableFairValueDisclosureDifference_label_en-US" xlink:label="lab_slm_AccruedInterestReceivableFairValueDisclosureDifference" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Accrued Interest Receivable, Fair Value Disclosure, Difference</link:label>
    <link:label id="lab_slm_AccruedInterestReceivableFairValueDisclosureDifference_documentation_en-US" xlink:label="lab_slm_AccruedInterestReceivableFairValueDisclosureDifference" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Accrued Interest Receivable, Fair Value Disclosure, Difference</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_slm_AccruedInterestReceivableFairValueDisclosureDifference" xlink:href="slm-20230331.xsd#slm_AccruedInterestReceivableFairValueDisclosureDifference"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_slm_AccruedInterestReceivableFairValueDisclosureDifference" xlink:to="lab_slm_AccruedInterestReceivableFairValueDisclosureDifference" xlink:type="arc" order="1"/>
    <link:label id="lab_slm_LoansPledgedAsCollateralPrincipalAmount_749bd215-8c03-4bb3-97c1-ea23b508f616_terseLabel_en-US" xlink:label="lab_slm_LoansPledgedAsCollateralPrincipalAmount" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Principal amount of collateral</link:label>
    <link:label id="lab_slm_LoansPledgedAsCollateralPrincipalAmount_label_en-US" xlink:label="lab_slm_LoansPledgedAsCollateralPrincipalAmount" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Loans Pledged As Collateral, Principal Amount</link:label>
    <link:label id="lab_slm_LoansPledgedAsCollateralPrincipalAmount_documentation_en-US" xlink:label="lab_slm_LoansPledgedAsCollateralPrincipalAmount" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Loans Pledged As Collateral, Principal Amount</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_slm_LoansPledgedAsCollateralPrincipalAmount" xlink:href="slm-20230331.xsd#slm_LoansPledgedAsCollateralPrincipalAmount"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_slm_LoansPledgedAsCollateralPrincipalAmount" xlink:to="lab_slm_LoansPledgedAsCollateralPrincipalAmount" xlink:type="arc" order="1"/>
    <link:label id="lab_slm_InterestIncomeonTaxIndemnificationReceivable_63898433-d8f2-414e-b233-3aedbdbb7a58_negatedTerseLabel_en-US" xlink:label="lab_slm_InterestIncomeonTaxIndemnificationReceivable" xlink:role="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Increase in tax indemnification receivable</link:label>
    <link:label id="lab_slm_InterestIncomeonTaxIndemnificationReceivable_label_en-US" xlink:label="lab_slm_InterestIncomeonTaxIndemnificationReceivable" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Interest Income on Tax Indemnification Receivable</link:label>
    <link:label id="lab_slm_InterestIncomeonTaxIndemnificationReceivable_documentation_en-US" xlink:label="lab_slm_InterestIncomeonTaxIndemnificationReceivable" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Interest Income on Tax Indemnification Receivable</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_slm_InterestIncomeonTaxIndemnificationReceivable" xlink:href="slm-20230331.xsd#slm_InterestIncomeonTaxIndemnificationReceivable"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_slm_InterestIncomeonTaxIndemnificationReceivable" xlink:to="lab_slm_InterestIncomeonTaxIndemnificationReceivable" xlink:type="arc" order="1"/>
    <link:label id="lab_slm_FinancingReceivableTroubledDebtRestructuringWriteDown_fabf8628-c77a-478e-88c6-d192e6725c9d_terseLabel_en-US" xlink:label="lab_slm_FinancingReceivableTroubledDebtRestructuringWriteDown" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Charge-Offs</link:label>
    <link:label id="lab_slm_FinancingReceivableTroubledDebtRestructuringWriteDown_label_en-US" xlink:label="lab_slm_FinancingReceivableTroubledDebtRestructuringWriteDown" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Financing Receivable, Troubled Debt Restructuring, Write-Down</link:label>
    <link:label id="lab_slm_FinancingReceivableTroubledDebtRestructuringWriteDown_documentation_en-US" xlink:label="lab_slm_FinancingReceivableTroubledDebtRestructuringWriteDown" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Financing Receivable, Troubled Debt Restructuring, Write-Down</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_slm_FinancingReceivableTroubledDebtRestructuringWriteDown" xlink:href="slm-20230331.xsd#slm_FinancingReceivableTroubledDebtRestructuringWriteDown"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_slm_FinancingReceivableTroubledDebtRestructuringWriteDown" xlink:to="lab_slm_FinancingReceivableTroubledDebtRestructuringWriteDown" xlink:type="arc" order="1"/>
    <link:label id="lab_dei_EntityAddressStateOrProvince_35139899-6384-48e1-ad3c-adf6d67d261d_terseLabel_en-US" xlink:label="lab_dei_EntityAddressStateOrProvince" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Entity Address, State or Province</link:label>
    <link:label id="lab_dei_EntityAddressStateOrProvince_label_en-US" xlink:label="lab_dei_EntityAddressStateOrProvince" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Entity Address, State or Province</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityAddressStateOrProvince" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_EntityAddressStateOrProvince"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_dei_EntityAddressStateOrProvince" xlink:to="lab_dei_EntityAddressStateOrProvince" xlink:type="arc" order="1"/>
    <link:label id="lab_slm_AdoptionOfNewAccountingPronouncementsPercentDeferredPerYear_4038c9c4-44e7-453b-9bb8-9e51bebfbe2a_terseLabel_en-US" xlink:label="lab_slm_AdoptionOfNewAccountingPronouncementsPercentDeferredPerYear" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Percentage amount deferred per year</link:label>
    <link:label id="lab_slm_AdoptionOfNewAccountingPronouncementsPercentDeferredPerYear_label_en-US" xlink:label="lab_slm_AdoptionOfNewAccountingPronouncementsPercentDeferredPerYear" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Adoption Of New Accounting Pronouncements, Percent Deferred Per Year</link:label>
    <link:label id="lab_slm_AdoptionOfNewAccountingPronouncementsPercentDeferredPerYear_documentation_en-US" xlink:label="lab_slm_AdoptionOfNewAccountingPronouncementsPercentDeferredPerYear" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Adoption Of New Accounting Pronouncements, Percent Deferred Per Year</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_slm_AdoptionOfNewAccountingPronouncementsPercentDeferredPerYear" xlink:href="slm-20230331.xsd#slm_AdoptionOfNewAccountingPronouncementsPercentDeferredPerYear"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_slm_AdoptionOfNewAccountingPronouncementsPercentDeferredPerYear" xlink:to="lab_slm_AdoptionOfNewAccountingPronouncementsPercentDeferredPerYear" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_SecuritiesFinancingTransactionTable_0d24c813-b2a2-4cd0-a079-7b9cba62adfe_terseLabel_en-US" xlink:label="lab_us-gaap_SecuritiesFinancingTransactionTable" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Securities Financing Transaction [Table]</link:label>
    <link:label id="lab_us-gaap_SecuritiesFinancingTransactionTable_label_en-US" xlink:label="lab_us-gaap_SecuritiesFinancingTransactionTable" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Securities Financing Transaction [Table]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SecuritiesFinancingTransactionTable" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_SecuritiesFinancingTransactionTable"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_SecuritiesFinancingTransactionTable" xlink:to="lab_us-gaap_SecuritiesFinancingTransactionTable" xlink:type="arc" order="1"/>
    <link:label id="lab_slm_FinancingReceivableCreditLossExpenseReversalOtherImpacts_43eb8ff4-14c4-4c07-b96e-dd20f0d45b0f_terseLabel_en-US" xlink:label="lab_slm_FinancingReceivableCreditLossExpenseReversalOtherImpacts" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Private Education Loan provision for credit losses, other impacts</link:label>
    <link:label id="lab_slm_FinancingReceivableCreditLossExpenseReversalOtherImpacts_label_en-US" xlink:label="lab_slm_FinancingReceivableCreditLossExpenseReversalOtherImpacts" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Financing Receivable, Credit Loss, Expense (Reversal), Other Impacts</link:label>
    <link:label id="lab_slm_FinancingReceivableCreditLossExpenseReversalOtherImpacts_documentation_en-US" xlink:label="lab_slm_FinancingReceivableCreditLossExpenseReversalOtherImpacts" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Financing Receivable, Credit Loss, Expense (Reversal), Other Impacts</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_slm_FinancingReceivableCreditLossExpenseReversalOtherImpacts" xlink:href="slm-20230331.xsd#slm_FinancingReceivableCreditLossExpenseReversalOtherImpacts"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_slm_FinancingReceivableCreditLossExpenseReversalOtherImpacts" xlink:to="lab_slm_FinancingReceivableCreditLossExpenseReversalOtherImpacts" xlink:type="arc" order="1"/>
    <link:label id="lab_slm_FinancialLiabilitiesFairValueDisclosureDifferenceBetweenCarryingValueandFairValue_833435be-cc49-47b8-afae-f2fb3898289d_totalLabel_en-US" xlink:label="lab_slm_FinancialLiabilitiesFairValueDisclosureDifferenceBetweenCarryingValueandFairValue" xlink:role="http://www.xbrl.org/2003/role/totalLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Total interest-bearing liabilities, difference</link:label>
    <link:label id="lab_slm_FinancialLiabilitiesFairValueDisclosureDifferenceBetweenCarryingValueandFairValue_label_en-US" xlink:label="lab_slm_FinancialLiabilitiesFairValueDisclosureDifferenceBetweenCarryingValueandFairValue" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Financial Liabilities Fair Value Disclosure, Difference Between Carrying Value and Fair Value</link:label>
    <link:label id="lab_slm_FinancialLiabilitiesFairValueDisclosureDifferenceBetweenCarryingValueandFairValue_documentation_en-US" xlink:label="lab_slm_FinancialLiabilitiesFairValueDisclosureDifferenceBetweenCarryingValueandFairValue" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Financial Liabilities Fair Value Disclosure, Difference Between Carrying Value and Fair Value</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_slm_FinancialLiabilitiesFairValueDisclosureDifferenceBetweenCarryingValueandFairValue" xlink:href="slm-20230331.xsd#slm_FinancialLiabilitiesFairValueDisclosureDifferenceBetweenCarryingValueandFairValue"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_slm_FinancialLiabilitiesFairValueDisclosureDifferenceBetweenCarryingValueandFairValue" xlink:to="lab_slm_FinancialLiabilitiesFairValueDisclosureDifferenceBetweenCarryingValueandFairValue" xlink:type="arc" order="1"/>
    <link:label id="lab_slm_SMBPrivateEducationLoanTrust2023AMember_d2a3185d-895d-439c-b5ee-347b282b96e0_terseLabel_en-US" xlink:label="lab_slm_SMBPrivateEducationLoanTrust2023AMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">2023-A</link:label>
    <link:label id="lab_slm_SMBPrivateEducationLoanTrust2023AMember_label_en-US" xlink:label="lab_slm_SMBPrivateEducationLoanTrust2023AMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">SMB Private Education Loan Trust 2023-A [Member]</link:label>
    <link:label id="lab_slm_SMBPrivateEducationLoanTrust2023AMember_documentation_en-US" xlink:label="lab_slm_SMBPrivateEducationLoanTrust2023AMember" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">SMB Private Education Loan Trust 2023-A</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_slm_SMBPrivateEducationLoanTrust2023AMember" xlink:href="slm-20230331.xsd#slm_SMBPrivateEducationLoanTrust2023AMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_slm_SMBPrivateEducationLoanTrust2023AMember" xlink:to="lab_slm_SMBPrivateEducationLoanTrust2023AMember" xlink:type="arc" order="1"/>
    <link:label id="lab_slm_OffBalanceSheetCreditLossLiabilityOtherProvisionBenefit_5e0dc585-82b5-4513-a927-39c55deced71_terseLabel_en-US" xlink:label="lab_slm_OffBalanceSheetCreditLossLiabilityOtherProvisionBenefit" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Other provision items</link:label>
    <link:label id="lab_slm_OffBalanceSheetCreditLossLiabilityOtherProvisionBenefit_label_en-US" xlink:label="lab_slm_OffBalanceSheetCreditLossLiabilityOtherProvisionBenefit" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Off-Balance Sheet, Credit Loss, Liability, Other Provision (Benefit)</link:label>
    <link:label id="lab_slm_OffBalanceSheetCreditLossLiabilityOtherProvisionBenefit_documentation_en-US" xlink:label="lab_slm_OffBalanceSheetCreditLossLiabilityOtherProvisionBenefit" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Off-Balance Sheet, Credit Loss, Liability, Other Provision (Benefit)</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_slm_OffBalanceSheetCreditLossLiabilityOtherProvisionBenefit" xlink:href="slm-20230331.xsd#slm_OffBalanceSheetCreditLossLiabilityOtherProvisionBenefit"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_slm_OffBalanceSheetCreditLossLiabilityOtherProvisionBenefit" xlink:to="lab_slm_OffBalanceSheetCreditLossLiabilityOtherProvisionBenefit" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_OtherInterestEarningAssets_17ce04aa-ce76-4ed4-9655-82ae8a640d13_terseLabel_en-US" xlink:label="lab_us-gaap_OtherInterestEarningAssets" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Other interest-earning assets</link:label>
    <link:label id="lab_us-gaap_OtherInterestEarningAssets_label_en-US" xlink:label="lab_us-gaap_OtherInterestEarningAssets" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Other Interest Earning Assets</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherInterestEarningAssets" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_OtherInterestEarningAssets"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_OtherInterestEarningAssets" xlink:to="lab_us-gaap_OtherInterestEarningAssets" xlink:type="arc" order="1"/>
    <link:label id="lab_slm_InterestBearingDepositsTableTextBlock_e22279a9-83e6-4c83-8388-2c4337401892_terseLabel_en-US" xlink:label="lab_slm_InterestBearingDepositsTableTextBlock" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Schedule of Interest Bearing Deposits</link:label>
    <link:label id="lab_slm_InterestBearingDepositsTableTextBlock_label_en-US" xlink:label="lab_slm_InterestBearingDepositsTableTextBlock" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Interest Bearing Deposits [Table Text Block]</link:label>
    <link:label id="lab_slm_InterestBearingDepositsTableTextBlock_documentation_en-US" xlink:label="lab_slm_InterestBearingDepositsTableTextBlock" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">[Table Text Block] for Interest Bearing Deposits [Table]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_slm_InterestBearingDepositsTableTextBlock" xlink:href="slm-20230331.xsd#slm_InterestBearingDepositsTableTextBlock"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_slm_InterestBearingDepositsTableTextBlock" xlink:to="lab_slm_InterestBearingDepositsTableTextBlock" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_CreditScoreFicoAxis_91d37e9a-b96b-4cd7-b6dc-57215c9e27eb_terseLabel_en-US" xlink:label="lab_us-gaap_CreditScoreFicoAxis" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Credit Score, FICO [Axis]</link:label>
    <link:label id="lab_us-gaap_CreditScoreFicoAxis_label_en-US" xlink:label="lab_us-gaap_CreditScoreFicoAxis" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Credit Score, FICO [Axis]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CreditScoreFicoAxis" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_CreditScoreFicoAxis"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_CreditScoreFicoAxis" xlink:to="lab_us-gaap_CreditScoreFicoAxis" xlink:type="arc" order="1"/>
    <link:label id="lab_slm_FinancingReceivableAllowanceForCreditLossExcludingAccruedInterestWriteoffOriginatedThreeYearsBeforeLatestFiscalYear_5a9bd9f0-e2f2-44fc-b79f-310417a0a2d1_negatedTerseLabel_en-US" xlink:label="lab_slm_FinancingReceivableAllowanceForCreditLossExcludingAccruedInterestWriteoffOriginatedThreeYearsBeforeLatestFiscalYear" xlink:role="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Current period gross charge-offs, Year 4</link:label>
    <link:label id="lab_slm_FinancingReceivableAllowanceForCreditLossExcludingAccruedInterestWriteoffOriginatedThreeYearsBeforeLatestFiscalYear_label_en-US" xlink:label="lab_slm_FinancingReceivableAllowanceForCreditLossExcludingAccruedInterestWriteoffOriginatedThreeYearsBeforeLatestFiscalYear" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Financing Receivable, Allowance for Credit Loss, Excluding Accrued Interest, Writeoff, Originated Three Years Before Latest Fiscal Year</link:label>
    <link:label id="lab_slm_FinancingReceivableAllowanceForCreditLossExcludingAccruedInterestWriteoffOriginatedThreeYearsBeforeLatestFiscalYear_documentation_en-US" xlink:label="lab_slm_FinancingReceivableAllowanceForCreditLossExcludingAccruedInterestWriteoffOriginatedThreeYearsBeforeLatestFiscalYear" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Financing Receivable, Allowance for Credit Loss, Excluding Accrued Interest, Writeoff, Originated Three Years Before Latest Fiscal Year</link:label>
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    <link:label id="lab_us-gaap_FinancingReceivableAllowanceForCreditLossExcludingAccruedInterest_2b9feebf-813c-441d-9d1f-be9795064f97_terseLabel_en-US" xlink:label="lab_us-gaap_FinancingReceivableAllowanceForCreditLossExcludingAccruedInterest" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Allowance for credit losses</link:label>
    <link:label id="lab_us-gaap_FinancingReceivableAllowanceForCreditLossExcludingAccruedInterest_1e8f5883-b5b0-49be-9f9d-bc646c453173_negatedLabel_en-US" xlink:label="lab_us-gaap_FinancingReceivableAllowanceForCreditLossExcludingAccruedInterest" xlink:role="http://www.xbrl.org/2009/role/negatedLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Allowance for credit losses</link:label>
    <link:label id="lab_us-gaap_FinancingReceivableAllowanceForCreditLossExcludingAccruedInterest_6d5195ed-1617-4a42-8f97-e588d48eeb2a_periodStartLabel_en-US" xlink:label="lab_us-gaap_FinancingReceivableAllowanceForCreditLossExcludingAccruedInterest" xlink:role="http://www.xbrl.org/2003/role/periodStartLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Beginning Balance</link:label>
    <link:label id="lab_us-gaap_FinancingReceivableAllowanceForCreditLossExcludingAccruedInterest_f8c3cdf7-7a50-482f-9035-5f2b773cbc58_periodEndLabel_en-US" xlink:label="lab_us-gaap_FinancingReceivableAllowanceForCreditLossExcludingAccruedInterest" xlink:role="http://www.xbrl.org/2003/role/periodEndLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Ending Balance</link:label>
    <link:label id="lab_us-gaap_FinancingReceivableAllowanceForCreditLossExcludingAccruedInterest_ef87d3ae-96c4-4644-a02b-045ab6bd0dac_negatedTotalLabel_en-US" xlink:label="lab_us-gaap_FinancingReceivableAllowanceForCreditLossExcludingAccruedInterest" xlink:role="http://www.xbrl.org/2009/role/negatedTotalLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Private Education Loans allowance for losses</link:label>
    <link:label id="lab_us-gaap_FinancingReceivableAllowanceForCreditLossExcludingAccruedInterest_label_en-US" xlink:label="lab_us-gaap_FinancingReceivableAllowanceForCreditLossExcludingAccruedInterest" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Financing Receivable, Allowance for Credit Loss, Excluding Accrued Interest</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinancingReceivableAllowanceForCreditLossExcludingAccruedInterest" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_FinancingReceivableAllowanceForCreditLossExcludingAccruedInterest"/>
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    <link:label id="lab_slm_AccruedInterestToBeCapitalizedAbstract_b5c1855f-8be9-4514-bdd5-a9ef840ec724_terseLabel_en-US" xlink:label="lab_slm_AccruedInterestToBeCapitalizedAbstract" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Accrued Interest to be Capitalized [Abstract]</link:label>
    <link:label id="lab_slm_AccruedInterestToBeCapitalizedAbstract_label_en-US" xlink:label="lab_slm_AccruedInterestToBeCapitalizedAbstract" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Accrued Interest to be Capitalized [Abstract]</link:label>
    <link:label id="lab_slm_AccruedInterestToBeCapitalizedAbstract_documentation_en-US" xlink:label="lab_slm_AccruedInterestToBeCapitalizedAbstract" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Accrued Interest to be Capitalized</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_slm_AccruedInterestToBeCapitalizedAbstract" xlink:href="slm-20230331.xsd#slm_AccruedInterestToBeCapitalizedAbstract"/>
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    <link:label id="lab_slm_FinancingReceivableAccruedInterestOriginationVintageOriginatedInCurrentFiscalYear_74397a4f-3422-44b4-9398-25a52ee04256_terseLabel_en-US" xlink:label="lab_slm_FinancingReceivableAccruedInterestOriginationVintageOriginatedInCurrentFiscalYear" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Total accrued interest by origination vintage, Year 1</link:label>
    <link:label id="lab_slm_FinancingReceivableAccruedInterestOriginationVintageOriginatedInCurrentFiscalYear_label_en-US" xlink:label="lab_slm_FinancingReceivableAccruedInterestOriginationVintageOriginatedInCurrentFiscalYear" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Financing Receivable, Accrued Interest, Origination Vintage, Originated in Current Fiscal Year</link:label>
    <link:label id="lab_slm_FinancingReceivableAccruedInterestOriginationVintageOriginatedInCurrentFiscalYear_documentation_en-US" xlink:label="lab_slm_FinancingReceivableAccruedInterestOriginationVintageOriginatedInCurrentFiscalYear" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Financing Receivable, Accrued Interest, Origination Vintage, Originated in Current Fiscal Year</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_slm_FinancingReceivableAccruedInterestOriginationVintageOriginatedInCurrentFiscalYear" xlink:href="slm-20230331.xsd#slm_FinancingReceivableAccruedInterestOriginationVintageOriginatedInCurrentFiscalYear"/>
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    <link:label id="lab_us-gaap_FinancingReceivableExcludingAccruedInterestYearFourOriginatedThreeYearsBeforeCurrentFiscalYear_80b11023-8d78-403b-88ee-eb31dab6705d_terseLabel_en-US" xlink:label="lab_us-gaap_FinancingReceivableExcludingAccruedInterestYearFourOriginatedThreeYearsBeforeCurrentFiscalYear" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Year 4</link:label>
    <link:label id="lab_us-gaap_FinancingReceivableExcludingAccruedInterestYearFourOriginatedThreeYearsBeforeCurrentFiscalYear_label_en-US" xlink:label="lab_us-gaap_FinancingReceivableExcludingAccruedInterestYearFourOriginatedThreeYearsBeforeCurrentFiscalYear" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Financing Receivable, Excluding Accrued Interest, Year Four, Originated, Three Years before Current Fiscal Year</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinancingReceivableExcludingAccruedInterestYearFourOriginatedThreeYearsBeforeCurrentFiscalYear" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_FinancingReceivableExcludingAccruedInterestYearFourOriginatedThreeYearsBeforeCurrentFiscalYear"/>
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    <link:label id="lab_us-gaap_VariableInterestEntityNotPrimaryBeneficiaryMember_0d436a74-ebeb-4ba1-954b-820f5c902b40_terseLabel_en-US" xlink:label="lab_us-gaap_VariableInterestEntityNotPrimaryBeneficiaryMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Variable Interest Entity, Not Primary Beneficiary</link:label>
    <link:label id="lab_us-gaap_VariableInterestEntityNotPrimaryBeneficiaryMember_label_en-US" xlink:label="lab_us-gaap_VariableInterestEntityNotPrimaryBeneficiaryMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Variable Interest Entity, Not Primary Beneficiary [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_VariableInterestEntityNotPrimaryBeneficiaryMember" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_VariableInterestEntityNotPrimaryBeneficiaryMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_VariableInterestEntityNotPrimaryBeneficiaryMember" xlink:to="lab_us-gaap_VariableInterestEntityNotPrimaryBeneficiaryMember" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_Liabilities_301a4e20-49c3-4856-a820-6c0c74dcc238_totalLabel_en-US" xlink:label="lab_us-gaap_Liabilities" xlink:role="http://www.xbrl.org/2003/role/totalLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Total liabilities</link:label>
    <link:label id="lab_us-gaap_Liabilities_label_en-US" xlink:label="lab_us-gaap_Liabilities" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Liabilities</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_Liabilities" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_Liabilities"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_Liabilities" xlink:to="lab_us-gaap_Liabilities" xlink:type="arc" order="1"/>
    <link:label id="lab_slm_SeasoningBasedOnMonthlyScheduledPaymentsDueFromThirtySevenToFortyEightPaymentsInPercent_a31b94b8-60ed-42de-a4ad-2d9c656389db_terseLabel_en-US" xlink:label="lab_slm_SeasoningBasedOnMonthlyScheduledPaymentsDueFromThirtySevenToFortyEightPaymentsInPercent" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Seasoning based on monthly scheduled payments due from 37 - 48 payments</link:label>
    <link:label id="lab_slm_SeasoningBasedOnMonthlyScheduledPaymentsDueFromThirtySevenToFortyEightPaymentsInPercent_label_en-US" xlink:label="lab_slm_SeasoningBasedOnMonthlyScheduledPaymentsDueFromThirtySevenToFortyEightPaymentsInPercent" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Seasoning Based On Monthly Scheduled Payments Due From Thirty Seven To Forty Eight Payments In Percent</link:label>
    <link:label id="lab_slm_SeasoningBasedOnMonthlyScheduledPaymentsDueFromThirtySevenToFortyEightPaymentsInPercent_documentation_en-US" xlink:label="lab_slm_SeasoningBasedOnMonthlyScheduledPaymentsDueFromThirtySevenToFortyEightPaymentsInPercent" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Seasoning based on monthly scheduled payments due from thirty seven to forty eight payments in percent.</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_slm_SeasoningBasedOnMonthlyScheduledPaymentsDueFromThirtySevenToFortyEightPaymentsInPercent" xlink:href="slm-20230331.xsd#slm_SeasoningBasedOnMonthlyScheduledPaymentsDueFromThirtySevenToFortyEightPaymentsInPercent"/>
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    <link:label id="lab_us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract_4c6615b4-d014-4682-9a3a-c3d46cee29b8_terseLabel_en-US" xlink:label="lab_us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Investing activities</link:label>
    <link:label id="lab_us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract_label_en-US" xlink:label="lab_us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Net Cash Provided by (Used in) Investing Activities [Abstract]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract" xlink:to="lab_us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract" xlink:type="arc" order="1"/>
    <link:label id="lab_slm_LoansInRepaymentOriginatedThreeYearsBeforeCurrentFiscalYear_c5d5c465-db1f-4fa9-8eac-a6b26344f3ff_terseLabel_en-US" xlink:label="lab_slm_LoansInRepaymentOriginatedThreeYearsBeforeCurrentFiscalYear" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Total Private Education Loans in forbearance, Year 4</link:label>
    <link:label id="lab_slm_LoansInRepaymentOriginatedThreeYearsBeforeCurrentFiscalYear_label_en-US" xlink:label="lab_slm_LoansInRepaymentOriginatedThreeYearsBeforeCurrentFiscalYear" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Loans In Repayment, Originated Three Years Before Current Fiscal Year</link:label>
    <link:label id="lab_slm_LoansInRepaymentOriginatedThreeYearsBeforeCurrentFiscalYear_documentation_en-US" xlink:label="lab_slm_LoansInRepaymentOriginatedThreeYearsBeforeCurrentFiscalYear" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Loans In Repayment, Originated Three Years Before Current Fiscal Year</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_slm_LoansInRepaymentOriginatedThreeYearsBeforeCurrentFiscalYear" xlink:href="slm-20230331.xsd#slm_LoansInRepaymentOriginatedThreeYearsBeforeCurrentFiscalYear"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_slm_LoansInRepaymentOriginatedThreeYearsBeforeCurrentFiscalYear" xlink:to="lab_slm_LoansInRepaymentOriginatedThreeYearsBeforeCurrentFiscalYear" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_LoansReceivableHeldForSaleNetNotPartOfDisposalGroup_30277063-7781-4a90-9c66-1ad61be362ea_terseLabel_en-US" xlink:label="lab_us-gaap_LoansReceivableHeldForSaleNetNotPartOfDisposalGroup" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Loans held for sale</link:label>
    <link:label id="lab_us-gaap_LoansReceivableHeldForSaleNetNotPartOfDisposalGroup_8533cedd-3dd6-409c-811a-b35d9e1c9774_verboseLabel_en-US" xlink:label="lab_us-gaap_LoansReceivableHeldForSaleNetNotPartOfDisposalGroup" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Loans held for sale</link:label>
    <link:label id="lab_us-gaap_LoansReceivableHeldForSaleNetNotPartOfDisposalGroup_label_en-US" xlink:label="lab_us-gaap_LoansReceivableHeldForSaleNetNotPartOfDisposalGroup" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Financing Receivable, Held-for-Sale, Not Part of Disposal Group, after Valuation Allowance</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LoansReceivableHeldForSaleNetNotPartOfDisposalGroup" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_LoansReceivableHeldForSaleNetNotPartOfDisposalGroup"/>
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    <link:label id="lab_dei_EntityCommonStockSharesOutstanding_425a5e0d-5a55-471a-b0c0-2b1082b96bfe_terseLabel_en-US" xlink:label="lab_dei_EntityCommonStockSharesOutstanding" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Entity Common Stock, Shares Outstanding</link:label>
    <link:label id="lab_dei_EntityCommonStockSharesOutstanding_label_en-US" xlink:label="lab_dei_EntityCommonStockSharesOutstanding" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Entity Common Stock, Shares Outstanding</link:label>
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    <link:label id="lab_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_524fb848-d11a-4706-99c5-2ab3e530de4f_terseLabel_en-US" xlink:label="lab_us-gaap_FairValueMeasurementsFairValueHierarchyDomain" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Fair Value, Measurements, Fair Value Hierarchy [Domain]</link:label>
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    <link:label id="lab_us-gaap_AssetsFairValueDisclosureAbstract_6ec395b3-17a4-4ec1-ae1a-de50a23ba173_terseLabel_en-US" xlink:label="lab_us-gaap_AssetsFairValueDisclosureAbstract" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Assets:</link:label>
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    <link:label id="lab_slm_NetIncreaseDecreaseInLoansHeldForInvestmentExcludingLoansAcquiredOriginatedAndSales_977e6f5c-7d7d-4e4f-9176-74059d94f03a_negatedLabel_en-US" xlink:label="lab_slm_NetIncreaseDecreaseInLoansHeldForInvestmentExcludingLoansAcquiredOriginatedAndSales" xlink:role="http://www.xbrl.org/2009/role/negatedLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Net (Increase) Decrease In Loans Held For Investment, Excluding Loans Acquired, Originated, And Sales</link:label>
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    <link:label id="lab_slm_CriteriaForLoansToBeConsideredAsNonperforming_150f0354-b709-4bfd-af2d-c73ebb7c40fe_terseLabel_en-US" xlink:label="lab_slm_CriteriaForLoansToBeConsideredAsNonperforming" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Criteria for loans to be considered as nonperforming (greater than)</link:label>
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    <link:label id="lab_slm_FinancingReceivableAllowanceForCreditLossExcludingAccruedInterestWriteoffOriginatedTwoYearsBeforeLatestFiscalYear_8fc72cba-7912-4cf7-8d74-e6818b592d04_negatedTerseLabel_en-US" xlink:label="lab_slm_FinancingReceivableAllowanceForCreditLossExcludingAccruedInterestWriteoffOriginatedTwoYearsBeforeLatestFiscalYear" xlink:role="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Current period gross charge-offs, Year 3</link:label>
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    <link:label id="lab_us-gaap_InvestmentsAbstract_acb4bcc1-aebc-4527-8931-e6bc54f25215_terseLabel_en-US" xlink:label="lab_us-gaap_InvestmentsAbstract" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Investments:</link:label>
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    <link:label id="lab_slm_Maturity2046Member_2c7d467e-471e-481a-bc54-9b309bb27509_terseLabel_en-US" xlink:label="lab_slm_Maturity2046Member" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">2046</link:label>
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    <link:label id="lab_slm_SeasoningBasedOnMonthlyScheduledPaymentsDueFromNotYetInRepaymentInPercent_6425c77e-23d6-402d-9af8-afe174ffae29_terseLabel_en-US" xlink:label="lab_slm_SeasoningBasedOnMonthlyScheduledPaymentsDueFromNotYetInRepaymentInPercent" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Seasoning based on monthly scheduled payments due from not yet in repayment</link:label>
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    <link:label id="lab_us-gaap_FinancingReceivablesEqualToGreaterThan90DaysPastDueMember_7359c14f-1f42-478d-b025-0187709e8ec8_terseLabel_en-US" xlink:label="lab_us-gaap_FinancingReceivablesEqualToGreaterThan90DaysPastDueMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Loan delinquent 90 days or greater past due</link:label>
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    <link:label id="lab_us-gaap_OtherComprehensiveIncomeLossCashFlowHedgeGainLossBeforeReclassificationAndTax_e8df8c4e-6a33-4271-b41d-de982693256a_terseLabel_en-US" xlink:label="lab_us-gaap_OtherComprehensiveIncomeLossCashFlowHedgeGainLossBeforeReclassificationAndTax" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Amount of gain (loss) recognized in other comprehensive income (loss)</link:label>
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    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossCashFlowHedgeGainLossBeforeReclassificationAndTax" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_OtherComprehensiveIncomeLossCashFlowHedgeGainLossBeforeReclassificationAndTax"/>
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    <link:label id="lab_us-gaap_GainLossOnFairValueHedgesRecognizedInEarnings_49c1ad77-b7e4-4ad2-a692-0b051ddc848a_terseLabel_en-US" xlink:label="lab_us-gaap_GainLossOnFairValueHedgesRecognizedInEarnings" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Interest recognized on derivatives</link:label>
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    <link:label id="lab_slm_NetincreaseinNOWaccountdeposits_ff8d2ef1-c550-4a95-8c35-08c74f7e8d84_terseLabel_en-US" xlink:label="lab_slm_NetincreaseinNOWaccountdeposits" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Net increase (decrease) in other deposits</link:label>
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    <link:label id="lab_slm_NetincreaseinNOWaccountdeposits_documentation_en-US" xlink:label="lab_slm_NetincreaseinNOWaccountdeposits" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Net increase in NOW account deposits</link:label>
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    <link:label id="lab_us-gaap_ProceedsFromSaleOfFinanceReceivables_38c28674-3b19-4e2f-8588-7274e66fa3d7_terseLabel_en-US" xlink:label="lab_us-gaap_ProceedsFromSaleOfFinanceReceivables" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Proceeds from sale of loans receivable</link:label>
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    <link:label id="lab_us-gaap_DebtSecuritiesAvailableForSaleTable_c17204e4-9a7b-45a9-b832-e2202d93ca47_terseLabel_en-US" xlink:label="lab_us-gaap_DebtSecuritiesAvailableForSaleTable" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Debt Securities, Available-for-sale [Table]</link:label>
    <link:label id="lab_us-gaap_DebtSecuritiesAvailableForSaleTable_label_en-US" xlink:label="lab_us-gaap_DebtSecuritiesAvailableForSaleTable" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Debt Securities, Available-for-Sale [Table]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtSecuritiesAvailableForSaleTable" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_DebtSecuritiesAvailableForSaleTable"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_DebtSecuritiesAvailableForSaleTable" xlink:to="lab_us-gaap_DebtSecuritiesAvailableForSaleTable" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipByIncomeStatementLocationByDerivativeInstrumentRiskTable_17d6877f-2a0d-4bd1-8aa0-698614f2ae9a_terseLabel_en-US" xlink:label="lab_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipByIncomeStatementLocationByDerivativeInstrumentRiskTable" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Derivative Instruments, Gain (Loss) [Table]</link:label>
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    <link:label id="lab_slm_RepaymentsMember_c6c742db-8776-47b5-9be0-d0d522907809_terseLabel_en-US" xlink:label="lab_slm_RepaymentsMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Seasoning</link:label>
    <link:label id="lab_slm_RepaymentsMember_label_en-US" xlink:label="lab_slm_RepaymentsMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Repayments [Member]</link:label>
    <link:label id="lab_slm_RepaymentsMember_documentation_en-US" xlink:label="lab_slm_RepaymentsMember" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Repayments credit quality indicators that are developed and used internally by the company.</link:label>
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    <link:label id="lab_us-gaap_DebtDisclosureAbstract_f3fcc4d2-6dcf-4e1c-bb4d-8cd1089baece_terseLabel_en-US" xlink:label="lab_us-gaap_DebtDisclosureAbstract" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Debt Disclosure [Abstract]</link:label>
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    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtDisclosureAbstract" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_DebtDisclosureAbstract"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_DebtDisclosureAbstract" xlink:to="lab_us-gaap_DebtDisclosureAbstract" xlink:type="arc" order="1"/>
    <link:label id="lab_slm_AdjustmentsToAdditionalPaidInCapitalDividendsEquivalentUnitsRelatedToEmployeeStockBasedCompensationPlans_6013f84c-4709-4bc8-b420-b5e44159fd78_terseLabel_en-US" xlink:label="lab_slm_AdjustmentsToAdditionalPaidInCapitalDividendsEquivalentUnitsRelatedToEmployeeStockBasedCompensationPlans" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Dividend equivalent units related to employee stock-based compensation plans</link:label>
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    <link:label id="lab_slm_AdjustmentsToAdditionalPaidInCapitalDividendsEquivalentUnitsRelatedToEmployeeStockBasedCompensationPlans_documentation_en-US" xlink:label="lab_slm_AdjustmentsToAdditionalPaidInCapitalDividendsEquivalentUnitsRelatedToEmployeeStockBasedCompensationPlans" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Adjustments to Additional Paid In Capital, Dividends Equivalent Units Related to employee Stock-Based Compensation Plans</link:label>
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    <link:label id="lab_us-gaap_UnsecuredDebtMember_746dbff5-8fc5-453d-95bb-91b110df3395_terseLabel_en-US" xlink:label="lab_us-gaap_UnsecuredDebtMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Unsecured borrowings</link:label>
    <link:label id="lab_us-gaap_UnsecuredDebtMember_label_en-US" xlink:label="lab_us-gaap_UnsecuredDebtMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Unsecured Debt [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_UnsecuredDebtMember" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_UnsecuredDebtMember"/>
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    <link:label id="lab_slm_UtahHousingCorporationBondsMember_caa0b7a2-bf59-4adc-8885-b0717ffdfaff_terseLabel_en-US" xlink:label="lab_slm_UtahHousingCorporationBondsMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Utah Housing Corporation bonds</link:label>
    <link:label id="lab_slm_UtahHousingCorporationBondsMember_label_en-US" xlink:label="lab_slm_UtahHousingCorporationBondsMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Utah Housing Corporation Bonds [Member]</link:label>
    <link:label id="lab_slm_UtahHousingCorporationBondsMember_documentation_en-US" xlink:label="lab_slm_UtahHousingCorporationBondsMember" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Utah Housing Corporation Bonds [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_slm_UtahHousingCorporationBondsMember" xlink:href="slm-20230331.xsd#slm_UtahHousingCorporationBondsMember"/>
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    <link:label id="lab_us-gaap_NetCashProvidedByUsedInFinancingActivities_7779a367-ba80-4889-b713-c1255c9fdc57_totalLabel_en-US" xlink:label="lab_us-gaap_NetCashProvidedByUsedInFinancingActivities" xlink:role="http://www.xbrl.org/2003/role/totalLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Total net cash provided by (used in) financing activities</link:label>
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    <link:label id="lab_us-gaap_AccountingPoliciesAbstract_610b7186-a546-4567-978c-c795d22c513b_terseLabel_en-US" xlink:label="lab_us-gaap_AccountingPoliciesAbstract" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Accounting Policies [Abstract]</link:label>
    <link:label id="lab_us-gaap_AccountingPoliciesAbstract_label_en-US" xlink:label="lab_us-gaap_AccountingPoliciesAbstract" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Accounting Policies [Abstract]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccountingPoliciesAbstract" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AccountingPoliciesAbstract"/>
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    <link:label id="lab_slm_GreaterThanNinetyDaysPastDueAccruedInterestReceivable_098227c1-e5ee-4a24-8fe9-9e586fa2ac14_terseLabel_en-US" xlink:label="lab_slm_GreaterThanNinetyDaysPastDueAccruedInterestReceivable" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">90 Days or Greater Past Due</link:label>
    <link:label id="lab_slm_GreaterThanNinetyDaysPastDueAccruedInterestReceivable_label_en-US" xlink:label="lab_slm_GreaterThanNinetyDaysPastDueAccruedInterestReceivable" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Greater Than Ninety Days Past Due Accrued Interest Receivable</link:label>
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    <link:label id="lab_us-gaap_StockholdersEquityAbstract_54130819-f387-4aa7-97aa-6f6cc3e59811_terseLabel_en-US" xlink:label="lab_us-gaap_StockholdersEquityAbstract" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Equity</link:label>
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    <link:label id="lab_us-gaap_TreasuryStockValueAcquiredParValueMethod_c4e9fc35-3754-48df-9770-0241a6624831_negatedTerseLabel_en-US" xlink:label="lab_us-gaap_TreasuryStockValueAcquiredParValueMethod" xlink:role="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Common stock repurchased</link:label>
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    <link:label id="lab_slm_FinancingReceivableCreditLossExpenseReversalExistingCommitments_2cb65580-33a3-47c7-a7cd-9141ccf6b2fe_terseLabel_en-US" xlink:label="lab_slm_FinancingReceivableCreditLossExpenseReversalExistingCommitments" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Provisions for unfunded loan commitments</link:label>
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    <link:label id="lab_slm_FinancingReceivableCreditLossExpenseReversalExistingCommitments_documentation_en-US" xlink:label="lab_slm_FinancingReceivableCreditLossExpenseReversalExistingCommitments" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Financing Receivable, Credit Loss, Expense (Reversal), Existing Commitments</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_slm_FinancingReceivableCreditLossExpenseReversalExistingCommitments" xlink:href="slm-20230331.xsd#slm_FinancingReceivableCreditLossExpenseReversalExistingCommitments"/>
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    <link:label id="lab_us-gaap_InvestmentIncomeInterestAndDividendAbstract_3b3e63c5-826d-4623-9faf-4908f9f72cd9_terseLabel_en-US" xlink:label="lab_us-gaap_InvestmentIncomeInterestAndDividendAbstract" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Interest income:</link:label>
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    <link:label id="lab_slm_LoansOriginatedFourYearsBeforeLatestFiscalYear_1c5dda8e-ef06-40d6-ade7-8b288c184a76_terseLabel_en-US" xlink:label="lab_slm_LoansOriginatedFourYearsBeforeLatestFiscalYear" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Total Private Education Loans, Year 5</link:label>
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    <link:label id="lab_us-gaap_ScheduleOfDerivativeInstrumentsInStatementOfFinancialPositionFairValueTextBlock_8a5a85d8-0fc0-419f-a63f-e385a7759654_terseLabel_en-US" xlink:label="lab_us-gaap_ScheduleOfDerivativeInstrumentsInStatementOfFinancialPositionFairValueTextBlock" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Schedule of Impact of Derivatives on the Consolidated Balance Sheet</link:label>
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    <link:label id="lab_dei_EntityEmergingGrowthCompany_1ba11456-ff74-4484-9254-9cf1f819b842_terseLabel_en-US" xlink:label="lab_dei_EntityEmergingGrowthCompany" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Entity Emerging Growth Company</link:label>
    <link:label id="lab_dei_EntityEmergingGrowthCompany_label_en-US" xlink:label="lab_dei_EntityEmergingGrowthCompany" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Entity Emerging Growth Company</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityEmergingGrowthCompany" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_EntityEmergingGrowthCompany"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_dei_EntityEmergingGrowthCompany" xlink:to="lab_dei_EntityEmergingGrowthCompany" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_CommonStockParOrStatedValuePerShare_94ba9ee2-891f-44a7-a31a-137d7e0d6967_verboseLabel_en-US" xlink:label="lab_us-gaap_CommonStockParOrStatedValuePerShare" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Common stock, par value (in dollars per share)</link:label>
    <link:label id="lab_us-gaap_CommonStockParOrStatedValuePerShare_label_en-US" xlink:label="lab_us-gaap_CommonStockParOrStatedValuePerShare" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Common Stock, Par or Stated Value Per Share</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockParOrStatedValuePerShare" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_CommonStockParOrStatedValuePerShare"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_CommonStockParOrStatedValuePerShare" xlink:to="lab_us-gaap_CommonStockParOrStatedValuePerShare" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_OtherComprehensiveIncomeLossCashFlowHedgeGainLossBeforeReclassificationAfterTax_7e6c76f8-01e6-42dc-8bc5-2a82e9cb4a6b_terseLabel_en-US" xlink:label="lab_us-gaap_OtherComprehensiveIncomeLossCashFlowHedgeGainLossBeforeReclassificationAfterTax" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Unrealized gains (losses) on cash flow hedges</link:label>
    <link:label id="lab_us-gaap_OtherComprehensiveIncomeLossCashFlowHedgeGainLossBeforeReclassificationAfterTax_label_en-US" xlink:label="lab_us-gaap_OtherComprehensiveIncomeLossCashFlowHedgeGainLossBeforeReclassificationAfterTax" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Other Comprehensive Income (Loss), Cash Flow Hedge, Gain (Loss), before Reclassification, after Tax</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossCashFlowHedgeGainLossBeforeReclassificationAfterTax" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_OtherComprehensiveIncomeLossCashFlowHedgeGainLossBeforeReclassificationAfterTax"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_OtherComprehensiveIncomeLossCashFlowHedgeGainLossBeforeReclassificationAfterTax" xlink:to="lab_us-gaap_OtherComprehensiveIncomeLossCashFlowHedgeGainLossBeforeReclassificationAfterTax" xlink:type="arc" order="1"/>
    <link:label id="lab_slm_PercentOfPrivateLoans_483b8c11-f106-4ead-95ac-3ada1565026c_terseLabel_en-US" xlink:label="lab_slm_PercentOfPrivateLoans" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Private education loans</link:label>
    <link:label id="lab_slm_PercentOfPrivateLoans_label_en-US" xlink:label="lab_slm_PercentOfPrivateLoans" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Percent Of Private Loans</link:label>
    <link:label id="lab_slm_PercentOfPrivateLoans_documentation_en-US" xlink:label="lab_slm_PercentOfPrivateLoans" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Percent of private loans</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_slm_PercentOfPrivateLoans" xlink:href="slm-20230331.xsd#slm_PercentOfPrivateLoans"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_slm_PercentOfPrivateLoans" xlink:to="lab_slm_PercentOfPrivateLoans" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_TimeDepositMaturitiesAfterRollingYearFive_f06e8bd6-0d5b-438c-8910-8db00ac1e583_terseLabel_en-US" xlink:label="lab_us-gaap_TimeDepositMaturitiesAfterRollingYearFive" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">After five years</link:label>
    <link:label id="lab_us-gaap_TimeDepositMaturitiesAfterRollingYearFive_label_en-US" xlink:label="lab_us-gaap_TimeDepositMaturitiesAfterRollingYearFive" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Time Deposit Maturities, after Rolling Year Five</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_TimeDepositMaturitiesAfterRollingYearFive" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_TimeDepositMaturitiesAfterRollingYearFive"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_TimeDepositMaturitiesAfterRollingYearFive" xlink:to="lab_us-gaap_TimeDepositMaturitiesAfterRollingYearFive" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_CommitmentsAndContingenciesDisclosureAbstract_a675b240-9f09-4c3d-bac1-07bd5b0326a5_terseLabel_en-US" xlink:label="lab_us-gaap_CommitmentsAndContingenciesDisclosureAbstract" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Commitments and Contingencies Disclosure [Abstract]</link:label>
    <link:label id="lab_us-gaap_CommitmentsAndContingenciesDisclosureAbstract_label_en-US" xlink:label="lab_us-gaap_CommitmentsAndContingenciesDisclosureAbstract" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Commitments and Contingencies Disclosure [Abstract]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommitmentsAndContingenciesDisclosureAbstract" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_CommitmentsAndContingenciesDisclosureAbstract"/>
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    <link:label id="lab_us-gaap_FairValueDisclosuresTextBlock_8302878b-c1e9-4c48-8a5f-a83327816672_terseLabel_en-US" xlink:label="lab_us-gaap_FairValueDisclosuresTextBlock" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Fair Value Measurements</link:label>
    <link:label id="lab_us-gaap_FairValueDisclosuresTextBlock_label_en-US" xlink:label="lab_us-gaap_FairValueDisclosuresTextBlock" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Fair Value Disclosures [Text Block]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueDisclosuresTextBlock" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_FairValueDisclosuresTextBlock"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_FairValueDisclosuresTextBlock" xlink:to="lab_us-gaap_FairValueDisclosuresTextBlock" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_AvailableForSaleSecuritiesContinuousUnrealizedLossPositionAccumulatedLossAbstract_3ba2d787-ae6a-45d3-ba97-08b5f95636a3_terseLabel_en-US" xlink:label="lab_us-gaap_AvailableForSaleSecuritiesContinuousUnrealizedLossPositionAccumulatedLossAbstract" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Less than 12 months</link:label>
    <link:label id="lab_us-gaap_AvailableForSaleSecuritiesContinuousUnrealizedLossPositionAccumulatedLossAbstract_label_en-US" xlink:label="lab_us-gaap_AvailableForSaleSecuritiesContinuousUnrealizedLossPositionAccumulatedLossAbstract" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Debt Securities, Available-for-Sale, Unrealized Loss Position, Accumulated Loss [Abstract]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AvailableForSaleSecuritiesContinuousUnrealizedLossPositionAccumulatedLossAbstract" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AvailableForSaleSecuritiesContinuousUnrealizedLossPositionAccumulatedLossAbstract"/>
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    <link:label id="lab_dei_TradingSymbol_021397ac-69c9-4cfa-9437-e319ef2835e9_terseLabel_en-US" xlink:label="lab_dei_TradingSymbol" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Trading Symbol</link:label>
    <link:label id="lab_dei_TradingSymbol_label_en-US" xlink:label="lab_dei_TradingSymbol" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Trading Symbol</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_dei_TradingSymbol" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_TradingSymbol"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_dei_TradingSymbol" xlink:to="lab_dei_TradingSymbol" xlink:type="arc" order="1"/>
    <link:label id="lab_dei_EntityFileNumber_0fad6988-68d4-48fc-9f27-9073442a0311_terseLabel_en-US" xlink:label="lab_dei_EntityFileNumber" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Entity File Number</link:label>
    <link:label id="lab_dei_EntityFileNumber_label_en-US" xlink:label="lab_dei_EntityFileNumber" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Entity File Number</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityFileNumber" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_EntityFileNumber"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_dei_EntityFileNumber" xlink:to="lab_dei_EntityFileNumber" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_TreasuryStockAcquiredAverageCostPerShare_8ef0db0f-06c5-497d-9a49-54b061994a56_terseLabel_en-US" xlink:label="lab_us-gaap_TreasuryStockAcquiredAverageCostPerShare" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Average purchase price per share (in dollars per share)</link:label>
    <link:label id="lab_us-gaap_TreasuryStockAcquiredAverageCostPerShare_label_en-US" xlink:label="lab_us-gaap_TreasuryStockAcquiredAverageCostPerShare" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Treasury Stock Acquired, Average Cost Per Share</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_TreasuryStockAcquiredAverageCostPerShare" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_TreasuryStockAcquiredAverageCostPerShare"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_TreasuryStockAcquiredAverageCostPerShare" xlink:to="lab_us-gaap_TreasuryStockAcquiredAverageCostPerShare" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFour_acfc4363-3064-477d-90bf-3847dc978ead_terseLabel_en-US" xlink:label="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFour" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Expected amortization of 2026</link:label>
    <link:label id="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFour_label_en-US" xlink:label="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFour" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Finite-Lived Intangible Asset, Expected Amortization, Year Four</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFour" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFour"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFour" xlink:to="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFour" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_InterestPayableCurrent_ef58d91f-739e-45a5-bc16-1426ec252a82_terseLabel_en-US" xlink:label="lab_us-gaap_InterestPayableCurrent" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Accrued interest on deposits</link:label>
    <link:label id="lab_us-gaap_InterestPayableCurrent_label_en-US" xlink:label="lab_us-gaap_InterestPayableCurrent" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Interest Payable, Current</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestPayableCurrent" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_InterestPayableCurrent"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_InterestPayableCurrent" xlink:to="lab_us-gaap_InterestPayableCurrent" xlink:type="arc" order="1"/>
    <link:label id="lab_slm_FinancingReceivableAfterAllowanceForCreditLossOriginatedTwoYearsBeforeCurrentFiscalYear_7a39ae8b-8ee9-4d9c-abf3-04ea1663bd99_terseLabel_en-US" xlink:label="lab_slm_FinancingReceivableAfterAllowanceForCreditLossOriginatedTwoYearsBeforeCurrentFiscalYear" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Private Education Loans, net, Year 3</link:label>
    <link:label id="lab_slm_FinancingReceivableAfterAllowanceForCreditLossOriginatedTwoYearsBeforeCurrentFiscalYear_label_en-US" xlink:label="lab_slm_FinancingReceivableAfterAllowanceForCreditLossOriginatedTwoYearsBeforeCurrentFiscalYear" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Financing Receivable, after Allowance for Credit Loss, Originated Two Years Before Current Fiscal Year</link:label>
    <link:label id="lab_slm_FinancingReceivableAfterAllowanceForCreditLossOriginatedTwoYearsBeforeCurrentFiscalYear_documentation_en-US" xlink:label="lab_slm_FinancingReceivableAfterAllowanceForCreditLossOriginatedTwoYearsBeforeCurrentFiscalYear" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Financing Receivable, after Allowance for Credit Loss, Originated Two Years Before Current Fiscal Year</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_slm_FinancingReceivableAfterAllowanceForCreditLossOriginatedTwoYearsBeforeCurrentFiscalYear" xlink:href="slm-20230331.xsd#slm_FinancingReceivableAfterAllowanceForCreditLossOriginatedTwoYearsBeforeCurrentFiscalYear"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_slm_FinancingReceivableAfterAllowanceForCreditLossOriginatedTwoYearsBeforeCurrentFiscalYear" xlink:to="lab_slm_FinancingReceivableAfterAllowanceForCreditLossOriginatedTwoYearsBeforeCurrentFiscalYear" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationByLiabilityClassDomain_cfaabe2e-6dc3-461d-b237-ab82cfad0ebf_terseLabel_en-US" xlink:label="lab_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationByLiabilityClassDomain" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Fair Value by Liability Class [Domain]</link:label>
    <link:label id="lab_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationByLiabilityClassDomain_label_en-US" xlink:label="lab_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationByLiabilityClassDomain" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Fair Value by Liability Class [Domain]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationByLiabilityClassDomain" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationByLiabilityClassDomain"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationByLiabilityClassDomain" xlink:to="lab_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationByLiabilityClassDomain" xlink:type="arc" order="1"/>
    <link:label id="lab_slm_A2022ShareRepurchaseProgramMember_848602c3-68d8-4b37-94bb-e54f8c08a7a0_terseLabel_en-US" xlink:label="lab_slm_A2022ShareRepurchaseProgramMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">2022 Share Repurchase Program</link:label>
    <link:label id="lab_slm_A2022ShareRepurchaseProgramMember_label_en-US" xlink:label="lab_slm_A2022ShareRepurchaseProgramMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">2022 Share Repurchase Program [Member]</link:label>
    <link:label id="lab_slm_A2022ShareRepurchaseProgramMember_documentation_en-US" xlink:label="lab_slm_A2022ShareRepurchaseProgramMember" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">2022 Share Repurchase Program</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_slm_A2022ShareRepurchaseProgramMember" xlink:href="slm-20230331.xsd#slm_A2022ShareRepurchaseProgramMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_slm_A2022ShareRepurchaseProgramMember" xlink:to="lab_slm_A2022ShareRepurchaseProgramMember" xlink:type="arc" order="1"/>
    <link:label id="lab_slm_PeriodOfDefermentForAdoptionOfNewAccountingPronouncements_fe45d5f5-84cc-4da1-8963-76cf76a9560f_terseLabel_en-US" xlink:label="lab_slm_PeriodOfDefermentForAdoptionOfNewAccountingPronouncements" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Period of deferment</link:label>
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    <link:label id="lab_slm_PeriodOfDefermentForAdoptionOfNewAccountingPronouncements_documentation_en-US" xlink:label="lab_slm_PeriodOfDefermentForAdoptionOfNewAccountingPronouncements" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Period Of Deferment For Adoption Of New Accounting Pronouncements</link:label>
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    <link:label id="lab_us-gaap_FinancingReceivableExcludingAccruedInterestCreditLossExpenseReversal_9ddc2b1b-a383-41ba-a9de-9226ee0184d4_negatedTerseLabel_en-US" xlink:label="lab_us-gaap_FinancingReceivableExcludingAccruedInterestCreditLossExpenseReversal" xlink:role="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Provision for current period</link:label>
    <link:label id="lab_us-gaap_FinancingReceivableExcludingAccruedInterestCreditLossExpenseReversal_label_en-US" xlink:label="lab_us-gaap_FinancingReceivableExcludingAccruedInterestCreditLossExpenseReversal" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Financing Receivable, Excluding Accrued Interest, Credit Loss Expense (Reversal)</link:label>
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    <link:label id="lab_slm_OtherLiabilitiesReserve_4813dcc7-bf8f-4d85-a960-ef87232a511f_terseLabel_en-US" xlink:label="lab_slm_OtherLiabilitiesReserve" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Other liabilities reserve</link:label>
    <link:label id="lab_slm_OtherLiabilitiesReserve_label_en-US" xlink:label="lab_slm_OtherLiabilitiesReserve" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Other Liabilities Reserve</link:label>
    <link:label id="lab_slm_OtherLiabilitiesReserve_documentation_en-US" xlink:label="lab_slm_OtherLiabilitiesReserve" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Other Liabilities Reserve</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_slm_OtherLiabilitiesReserve" xlink:href="slm-20230331.xsd#slm_OtherLiabilitiesReserve"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_slm_OtherLiabilitiesReserve" xlink:to="lab_slm_OtherLiabilitiesReserve" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_DerivativeLiabilitiesAbstract_20bcc831-db57-46f7-bb44-f5baf5bc5b15_terseLabel_en-US" xlink:label="lab_us-gaap_DerivativeLiabilitiesAbstract" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Other Liabilities</link:label>
    <link:label id="lab_us-gaap_DerivativeLiabilitiesAbstract_label_en-US" xlink:label="lab_us-gaap_DerivativeLiabilitiesAbstract" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Derivative Liability [Abstract]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeLiabilitiesAbstract" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_DerivativeLiabilitiesAbstract"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_DerivativeLiabilitiesAbstract" xlink:to="lab_us-gaap_DerivativeLiabilitiesAbstract" xlink:type="arc" order="1"/>
    <link:label id="lab_slm_NetProceedsFromSalesOfStudentLoansHeldForSalePrincipal_137fa8c4-8f1a-485d-beec-5163723a69a0_terseLabel_en-US" xlink:label="lab_slm_NetProceedsFromSalesOfStudentLoansHeldForSalePrincipal" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Net proceeds from sales of loans held for investment, principal</link:label>
    <link:label id="lab_slm_NetProceedsFromSalesOfStudentLoansHeldForSalePrincipal_label_en-US" xlink:label="lab_slm_NetProceedsFromSalesOfStudentLoansHeldForSalePrincipal" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Net Proceeds From Sales Of Student Loans Held For Sale, Principal</link:label>
    <link:label id="lab_slm_NetProceedsFromSalesOfStudentLoansHeldForSalePrincipal_documentation_en-US" xlink:label="lab_slm_NetProceedsFromSalesOfStudentLoansHeldForSalePrincipal" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Net Proceeds From Sales Of Student Loans Held For Sale, Principal</link:label>
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    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_slm_NetProceedsFromSalesOfStudentLoansHeldForSalePrincipal" xlink:to="lab_slm_NetProceedsFromSalesOfStudentLoansHeldForSalePrincipal" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_ComprehensiveIncomeNetOfTaxIncludingPortionAttributableToNoncontrollingInterestAbstract_6d3b53fd-089b-44d2-ac20-19d10f03d0e3_terseLabel_en-US" xlink:label="lab_us-gaap_ComprehensiveIncomeNetOfTaxIncludingPortionAttributableToNoncontrollingInterestAbstract" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Other comprehensive income (loss):</link:label>
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    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ComprehensiveIncomeNetOfTaxIncludingPortionAttributableToNoncontrollingInterestAbstract" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ComprehensiveIncomeNetOfTaxIncludingPortionAttributableToNoncontrollingInterestAbstract"/>
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    <link:label id="lab_slm_FinancingReceivableAllowanceForCreditLossExcludingAccruedInterestWriteoffOriginatedInFiscalYearBeforeLatestFiscalYear_d7530e58-8cf0-479d-a0d4-b0df4b6a2e06_negatedTerseLabel_en-US" xlink:label="lab_slm_FinancingReceivableAllowanceForCreditLossExcludingAccruedInterestWriteoffOriginatedInFiscalYearBeforeLatestFiscalYear" xlink:role="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Current period gross charge-offs, Year 2</link:label>
    <link:label id="lab_slm_FinancingReceivableAllowanceForCreditLossExcludingAccruedInterestWriteoffOriginatedInFiscalYearBeforeLatestFiscalYear_label_en-US" xlink:label="lab_slm_FinancingReceivableAllowanceForCreditLossExcludingAccruedInterestWriteoffOriginatedInFiscalYearBeforeLatestFiscalYear" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Financing Receivable, Allowance for Credit Loss, Excluding Accrued Interest, Writeoff, Originated In Fiscal Year Before Latest Fiscal Year</link:label>
    <link:label id="lab_slm_FinancingReceivableAllowanceForCreditLossExcludingAccruedInterestWriteoffOriginatedInFiscalYearBeforeLatestFiscalYear_documentation_en-US" xlink:label="lab_slm_FinancingReceivableAllowanceForCreditLossExcludingAccruedInterestWriteoffOriginatedInFiscalYearBeforeLatestFiscalYear" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Financing Receivable, Allowance for Credit Loss, Excluding Accrued Interest, Writeoff, Originated In Fiscal Year Before Latest Fiscal Year</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_slm_FinancingReceivableAllowanceForCreditLossExcludingAccruedInterestWriteoffOriginatedInFiscalYearBeforeLatestFiscalYear" xlink:href="slm-20230331.xsd#slm_FinancingReceivableAllowanceForCreditLossExcludingAccruedInterestWriteoffOriginatedInFiscalYearBeforeLatestFiscalYear"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_slm_FinancingReceivableAllowanceForCreditLossExcludingAccruedInterestWriteoffOriginatedInFiscalYearBeforeLatestFiscalYear" xlink:to="lab_slm_FinancingReceivableAllowanceForCreditLossExcludingAccruedInterestWriteoffOriginatedInFiscalYearBeforeLatestFiscalYear" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_PreferredStockValueOutstanding_2c30cd78-4126-4b9a-bec8-5b24c7e14e4c_terseLabel_en-US" xlink:label="lab_us-gaap_PreferredStockValueOutstanding" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Preferred stock, par value $0.20 per share, 20&#160;million shares authorized: Series B: 2.5 million and 2.5 million shares issued, respectively, at stated value of $100 per share</link:label>
    <link:label id="lab_us-gaap_PreferredStockValueOutstanding_label_en-US" xlink:label="lab_us-gaap_PreferredStockValueOutstanding" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Preferred Stock, Value, Outstanding</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PreferredStockValueOutstanding" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_PreferredStockValueOutstanding"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_PreferredStockValueOutstanding" xlink:to="lab_us-gaap_PreferredStockValueOutstanding" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_DerivativeInstrumentsNotDesignatedAsHedgingInstrumentsGainLossNetAbstract_368e4158-db8b-4bb5-bd6f-67185b1634f3_terseLabel_en-US" xlink:label="lab_us-gaap_DerivativeInstrumentsNotDesignatedAsHedgingInstrumentsGainLossNetAbstract" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Trading</link:label>
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    <link:label id="lab_us-gaap_EarningsPerShareBasic_b725ef26-faaf-4044-9873-d2f324b0f154_verboseLabel_en-US" xlink:label="lab_us-gaap_EarningsPerShareBasic" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Basic earnings per common share (in dollars per share)</link:label>
    <link:label id="lab_us-gaap_EarningsPerShareBasic_21ce279f-0e17-4972-afab-042c2d714592_terseLabel_en-US" xlink:label="lab_us-gaap_EarningsPerShareBasic" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Basic earnings per common share (in dollars per share)</link:label>
    <link:label id="lab_us-gaap_EarningsPerShareBasic_label_en-US" xlink:label="lab_us-gaap_EarningsPerShareBasic" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Earnings Per Share, Basic</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EarningsPerShareBasic" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_EarningsPerShareBasic"/>
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    <link:label id="lab_slm_FinancingReceivableAccruedInterestOriginationVintageBeforeAllowanceForCreditLoss_ce2611a0-87b1-4eec-9fde-818317850f61_totalLabel_en-US" xlink:label="lab_slm_FinancingReceivableAccruedInterestOriginationVintageBeforeAllowanceForCreditLoss" xlink:role="http://www.xbrl.org/2003/role/totalLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Total accrued interest by origination vintage</link:label>
    <link:label id="lab_slm_FinancingReceivableAccruedInterestOriginationVintageBeforeAllowanceForCreditLoss_label_en-US" xlink:label="lab_slm_FinancingReceivableAccruedInterestOriginationVintageBeforeAllowanceForCreditLoss" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Financing Receivable, Accrued Interest, Origination Vintage, before Allowance for Credit Loss</link:label>
    <link:label id="lab_slm_FinancingReceivableAccruedInterestOriginationVintageBeforeAllowanceForCreditLoss_documentation_en-US" xlink:label="lab_slm_FinancingReceivableAccruedInterestOriginationVintageBeforeAllowanceForCreditLoss" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Financing Receivable, Accrued Interest, Origination Vintage, before Allowance for Credit Loss</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_slm_FinancingReceivableAccruedInterestOriginationVintageBeforeAllowanceForCreditLoss" xlink:href="slm-20230331.xsd#slm_FinancingReceivableAccruedInterestOriginationVintageBeforeAllowanceForCreditLoss"/>
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    <link:label id="lab_slm_Maturity2058Member_53dc49a7-55c4-4155-84f7-869825b3f078_terseLabel_en-US" xlink:label="lab_slm_Maturity2058Member" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">2058</link:label>
    <link:label id="lab_slm_Maturity2058Member_label_en-US" xlink:label="lab_slm_Maturity2058Member" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Maturity 2058 [Member]</link:label>
    <link:label id="lab_slm_Maturity2058Member_documentation_en-US" xlink:label="lab_slm_Maturity2058Member" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Maturity 2058</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_slm_Maturity2058Member" xlink:href="slm-20230331.xsd#slm_Maturity2058Member"/>
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    <link:label id="lab_us-gaap_CapitalRequiredToBeWellCapitalizedToRiskWeightedAssets_1d808171-07e4-4c8d-ab15-be0bdfc0c1b4_terseLabel_en-US" xlink:label="lab_us-gaap_CapitalRequiredToBeWellCapitalizedToRiskWeightedAssets" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Total Capital (to Risk-Weighted Assets)</link:label>
    <link:label id="lab_us-gaap_CapitalRequiredToBeWellCapitalizedToRiskWeightedAssets_label_en-US" xlink:label="lab_us-gaap_CapitalRequiredToBeWellCapitalizedToRiskWeightedAssets" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Banking Regulation, Total Risk-Based Capital Ratio, Well Capitalized, Minimum</link:label>
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    <link:label id="lab_us-gaap_ScheduleOfAccountsNotesLoansAndFinancingReceivableTable_784bd70f-3806-4613-8798-95aa9cfa451e_terseLabel_en-US" xlink:label="lab_us-gaap_ScheduleOfAccountsNotesLoansAndFinancingReceivableTable" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Schedule of Accounts, Notes, Loans and Financing Receivable [Table]</link:label>
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    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfAccountsNotesLoansAndFinancingReceivableTable" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ScheduleOfAccountsNotesLoansAndFinancingReceivableTable"/>
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    <link:label id="lab_us-gaap_DebtSecuritiesAvailableForSaleAllowanceForCreditLoss_3ca7eeea-14d6-4aef-bae6-aa93b36754ae_terseLabel_en-US" xlink:label="lab_us-gaap_DebtSecuritiesAvailableForSaleAllowanceForCreditLoss" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Allowance for credit losses</link:label>
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    <link:label id="lab_us-gaap_FairValueByBalanceSheetGroupingTable_c4427d89-c17b-4901-9ce5-5f2149184e02_terseLabel_en-US" xlink:label="lab_us-gaap_FairValueByBalanceSheetGroupingTable" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Fair Value, by Balance Sheet Grouping [Table]</link:label>
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    <link:label id="lab_us-gaap_PortionAtFairValueFairValueDisclosureMember_ed222dba-6451-45ce-a73b-b7bab7c757f3_terseLabel_en-US" xlink:label="lab_us-gaap_PortionAtFairValueFairValueDisclosureMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Portion at Fair Value Measurement</link:label>
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    <link:label id="lab_slm_StockholdersEquityAttributabletoParentExcludingTreasuryStock_d8530bd6-63a2-4774-bdd9-125d241555d7_totalLabel_en-US" xlink:label="lab_slm_StockholdersEquityAttributabletoParentExcludingTreasuryStock" xlink:role="http://www.xbrl.org/2003/role/totalLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Total SLM Corporation stockholders&#8217; equity before treasury stock</link:label>
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    <link:label id="lab_us-gaap_PaymentsForRepurchaseOfCommonStock_7410c8e4-c9fe-4d93-92cd-b62b41ca52cf_negatedTerseLabel_en-US" xlink:label="lab_us-gaap_PaymentsForRepurchaseOfCommonStock" xlink:role="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Common stock repurchased</link:label>
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    <link:label id="lab_slm_FinancingReceivableAfterAllowanceForCreditLossOriginatedInFiscalYearBeforeLatestFiscalYear_76b05fcb-79a3-4370-a5a6-be66472ec3a8_terseLabel_en-US" xlink:label="lab_slm_FinancingReceivableAfterAllowanceForCreditLossOriginatedInFiscalYearBeforeLatestFiscalYear" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Private Education Loans, net, Year 2</link:label>
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    <link:label id="lab_us-gaap_GainLossOnDerivativeInstrumentsNetPretax_507fdae8-a122-4a2b-a02b-dec377c02b58_terseLabel_en-US" xlink:label="lab_us-gaap_GainLossOnDerivativeInstrumentsNetPretax" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Gains (losses) on derivatives and hedging activities, net</link:label>
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    <link:label id="lab_slm_FinancingReceivableAllowanceForCreditLossOriginatedFiveYearsBeforeCurrentFiscalYear_e4f4df6d-d047-45b9-a8ee-89d280f14794_negatedTerseLabel_en-US" xlink:label="lab_slm_FinancingReceivableAllowanceForCreditLossOriginatedFiveYearsBeforeCurrentFiscalYear" xlink:role="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Private Education Loans allowance for losses, After Year 5</link:label>
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    <link:label id="lab_slm_LoansGrossOriginatedInFiscalYearBeforeLatestFiscalYear_6c719ed5-caa1-4ce1-a302-d58b6340e349_terseLabel_en-US" xlink:label="lab_slm_LoansGrossOriginatedInFiscalYearBeforeLatestFiscalYear" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Total Private Education Loans, gross, Year 2</link:label>
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    <link:label id="lab_us-gaap_DebtSecuritiesAvailableForSaleContinuousUnrealizedLossPositionLessThan12Months_48428731-e548-455f-a4a0-b4231fa49748_terseLabel_en-US" xlink:label="lab_us-gaap_DebtSecuritiesAvailableForSaleContinuousUnrealizedLossPositionLessThan12Months" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Estimated Fair Value</link:label>
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    <link:label id="lab_slm_FinancingReceivableAllowanceForCreditLossWriteoffAfterRecoveryOriginatedThreeYearsBeforeCurrentFiscalYear_documentation_en-US" xlink:label="lab_slm_FinancingReceivableAllowanceForCreditLossWriteoffAfterRecoveryOriginatedThreeYearsBeforeCurrentFiscalYear" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Financing Receivable, Allowance for Credit Loss, Writeoff, after Recovery, Originated Three Years Before Current Fiscal Year</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_slm_FinancingReceivableAllowanceForCreditLossWriteoffAfterRecoveryOriginatedThreeYearsBeforeCurrentFiscalYear" xlink:href="slm-20230331.xsd#slm_FinancingReceivableAllowanceForCreditLossWriteoffAfterRecoveryOriginatedThreeYearsBeforeCurrentFiscalYear"/>
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    <link:label id="lab_slm_PercentOfBalanceAbstract_c70b67fe-2bf8-463b-9a80-125365318990_terseLabel_en-US" xlink:label="lab_slm_PercentOfBalanceAbstract" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">% of Balance</link:label>
    <link:label id="lab_slm_PercentOfBalanceAbstract_label_en-US" xlink:label="lab_slm_PercentOfBalanceAbstract" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Percent Of Balance [Abstract]</link:label>
    <link:label id="lab_slm_PercentOfBalanceAbstract_documentation_en-US" xlink:label="lab_slm_PercentOfBalanceAbstract" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Percent Of Balance</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_slm_PercentOfBalanceAbstract" xlink:href="slm-20230331.xsd#slm_PercentOfBalanceAbstract"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_slm_PercentOfBalanceAbstract" xlink:to="lab_slm_PercentOfBalanceAbstract" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_ScheduleOfComplianceWithRegulatoryCapitalRequirementsUnderBankingRegulationsTable_0cb4be90-2df9-41dd-92d2-1248f7d86e98_terseLabel_en-US" xlink:label="lab_us-gaap_ScheduleOfComplianceWithRegulatoryCapitalRequirementsUnderBankingRegulationsTable" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Schedule of Compliance with Regulatory Capital Requirements under Banking Regulations [Table]</link:label>
    <link:label id="lab_us-gaap_ScheduleOfComplianceWithRegulatoryCapitalRequirementsUnderBankingRegulationsTable_label_en-US" xlink:label="lab_us-gaap_ScheduleOfComplianceWithRegulatoryCapitalRequirementsUnderBankingRegulationsTable" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Schedule of Compliance with Regulatory Capital Requirements under Banking Regulations [Table]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfComplianceWithRegulatoryCapitalRequirementsUnderBankingRegulationsTable" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ScheduleOfComplianceWithRegulatoryCapitalRequirementsUnderBankingRegulationsTable"/>
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    <link:label id="lab_slm_FinancingReceivableLoansInForbearanceOriginatedInCurrentFiscalYear_5d5f81f4-efab-4165-a2c7-132e8a2f2522_terseLabel_en-US" xlink:label="lab_slm_FinancingReceivableLoansInForbearanceOriginatedInCurrentFiscalYear" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Total Private Education Loans in forbearance, Year 1</link:label>
    <link:label id="lab_slm_FinancingReceivableLoansInForbearanceOriginatedInCurrentFiscalYear_label_en-US" xlink:label="lab_slm_FinancingReceivableLoansInForbearanceOriginatedInCurrentFiscalYear" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Financing Receivable, Loans In Forbearance, Originated In Current Fiscal Year</link:label>
    <link:label id="lab_slm_FinancingReceivableLoansInForbearanceOriginatedInCurrentFiscalYear_documentation_en-US" xlink:label="lab_slm_FinancingReceivableLoansInForbearanceOriginatedInCurrentFiscalYear" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Financing Receivable, Loans In Forbearance, Originated In Current Fiscal Year</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_slm_FinancingReceivableLoansInForbearanceOriginatedInCurrentFiscalYear" xlink:href="slm-20230331.xsd#slm_FinancingReceivableLoansInForbearanceOriginatedInCurrentFiscalYear"/>
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    <link:label id="lab_slm_LoansInRepaymentOriginatedInFiscalYearBeforeLatestFiscalYear_0a7f8958-5098-48c2-95a1-53ddae473fe0_terseLabel_en-US" xlink:label="lab_slm_LoansInRepaymentOriginatedInFiscalYearBeforeLatestFiscalYear" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Total Private Education Loans in forbearance, Year 2</link:label>
    <link:label id="lab_slm_LoansInRepaymentOriginatedInFiscalYearBeforeLatestFiscalYear_label_en-US" xlink:label="lab_slm_LoansInRepaymentOriginatedInFiscalYearBeforeLatestFiscalYear" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Loans In Repayment, Originated In Fiscal Year Before Latest Fiscal Year</link:label>
    <link:label id="lab_slm_LoansInRepaymentOriginatedInFiscalYearBeforeLatestFiscalYear_documentation_en-US" xlink:label="lab_slm_LoansInRepaymentOriginatedInFiscalYearBeforeLatestFiscalYear" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Loans In Repayment, Originated In Fiscal Year Before Latest Fiscal Year</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_slm_LoansInRepaymentOriginatedInFiscalYearBeforeLatestFiscalYear" xlink:href="slm-20230331.xsd#slm_LoansInRepaymentOriginatedInFiscalYearBeforeLatestFiscalYear"/>
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    <link:label id="lab_slm_WithCosignerMember_f9410dab-ff2e-4f51-83df-30d644641d7f_terseLabel_en-US" xlink:label="lab_slm_WithCosignerMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">With cosigner</link:label>
    <link:label id="lab_slm_WithCosignerMember_label_en-US" xlink:label="lab_slm_WithCosignerMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">With Cosigner [Member]</link:label>
    <link:label id="lab_slm_WithCosignerMember_documentation_en-US" xlink:label="lab_slm_WithCosignerMember" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">With Cosigner [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_slm_WithCosignerMember" xlink:href="slm-20230331.xsd#slm_WithCosignerMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_slm_WithCosignerMember" xlink:to="lab_slm_WithCosignerMember" xlink:type="arc" order="1"/>
    <link:label id="lab_slm_AccruedInterestToBeCapitalizedCollectivelyEvaluatedForImpairment_00d5495a-e548-4229-b4fb-125111fd096c_terseLabel_en-US" xlink:label="lab_slm_AccruedInterestToBeCapitalizedCollectivelyEvaluatedForImpairment" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Ending balance: collectively evaluated for impairment</link:label>
    <link:label id="lab_slm_AccruedInterestToBeCapitalizedCollectivelyEvaluatedForImpairment_label_en-US" xlink:label="lab_slm_AccruedInterestToBeCapitalizedCollectivelyEvaluatedForImpairment" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Accrued Interest to be Capitalized, Collectively Evaluated for Impairment</link:label>
    <link:label id="lab_slm_AccruedInterestToBeCapitalizedCollectivelyEvaluatedForImpairment_documentation_en-US" xlink:label="lab_slm_AccruedInterestToBeCapitalizedCollectivelyEvaluatedForImpairment" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Accrued Interest to be Capitalized, Collectively Evaluated for Impairment</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_slm_AccruedInterestToBeCapitalizedCollectivelyEvaluatedForImpairment" xlink:href="slm-20230331.xsd#slm_AccruedInterestToBeCapitalizedCollectivelyEvaluatedForImpairment"/>
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    <link:label id="lab_us-gaap_FinancingReceivableCreditQualityIndicatorsTableTextBlock_da187e02-4fed-4923-b192-8f75d4a2e409_terseLabel_en-US" xlink:label="lab_us-gaap_FinancingReceivableCreditQualityIndicatorsTableTextBlock" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Schedule of Private Education Loan Portfolio Stratified by Key Credit Quality Indicators</link:label>
    <link:label id="lab_us-gaap_FinancingReceivableCreditQualityIndicatorsTableTextBlock_label_en-US" xlink:label="lab_us-gaap_FinancingReceivableCreditQualityIndicatorsTableTextBlock" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Financing Receivable Credit Quality Indicators [Table Text Block]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinancingReceivableCreditQualityIndicatorsTableTextBlock" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_FinancingReceivableCreditQualityIndicatorsTableTextBlock"/>
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    <link:label id="lab_slm_InterestRateReductionAndTermExtensionMember_91ef9c07-f5ee-4e23-a004-5b8bb3cba5aa_terseLabel_en-US" xlink:label="lab_slm_InterestRateReductionAndTermExtensionMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Combination - Interest Rate Reduction and Term Extension</link:label>
    <link:label id="lab_slm_InterestRateReductionAndTermExtensionMember_label_en-US" xlink:label="lab_slm_InterestRateReductionAndTermExtensionMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Interest Rate Reduction And Term Extension [Member]</link:label>
    <link:label id="lab_slm_InterestRateReductionAndTermExtensionMember_documentation_en-US" xlink:label="lab_slm_InterestRateReductionAndTermExtensionMember" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Interest Rate Reduction And Term Extension</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_slm_InterestRateReductionAndTermExtensionMember" xlink:href="slm-20230331.xsd#slm_InterestRateReductionAndTermExtensionMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_slm_InterestRateReductionAndTermExtensionMember" xlink:to="lab_slm_InterestRateReductionAndTermExtensionMember" xlink:type="arc" order="1"/>
    <link:label id="lab_slm_DelinquenciesAsPercentageOfLoansInRepaymentOriginatedFiveYearsBeforeCurrentFiscalYear_627e72d6-90b4-40f9-ab6e-2e63752fc6ef_terseLabel_en-US" xlink:label="lab_slm_DelinquenciesAsPercentageOfLoansInRepaymentOriginatedFiveYearsBeforeCurrentFiscalYear" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Delinquent Private Education Loans in repayment as a percentage of Private Education Loans in repayment, After Year 5</link:label>
    <link:label id="lab_slm_DelinquenciesAsPercentageOfLoansInRepaymentOriginatedFiveYearsBeforeCurrentFiscalYear_label_en-US" xlink:label="lab_slm_DelinquenciesAsPercentageOfLoansInRepaymentOriginatedFiveYearsBeforeCurrentFiscalYear" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Delinquencies As Percentage Of Loans In Repayment, Originated Five Years Before Current Fiscal Year</link:label>
    <link:label id="lab_slm_DelinquenciesAsPercentageOfLoansInRepaymentOriginatedFiveYearsBeforeCurrentFiscalYear_documentation_en-US" xlink:label="lab_slm_DelinquenciesAsPercentageOfLoansInRepaymentOriginatedFiveYearsBeforeCurrentFiscalYear" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Delinquencies As Percentage Of Loans In Repayment, Originated Five Or More Years Before Current Fiscal Year</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_slm_DelinquenciesAsPercentageOfLoansInRepaymentOriginatedFiveYearsBeforeCurrentFiscalYear" xlink:href="slm-20230331.xsd#slm_DelinquenciesAsPercentageOfLoansInRepaymentOriginatedFiveYearsBeforeCurrentFiscalYear"/>
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    <link:label id="lab_us-gaap_FinancingReceivableExcludingAccruedInterestYearTwoOriginatedFiscalYearBeforeCurrentFiscalYear_e51f402a-860a-41fd-b514-8d8f4fe55376_terseLabel_en-US" xlink:label="lab_us-gaap_FinancingReceivableExcludingAccruedInterestYearTwoOriginatedFiscalYearBeforeCurrentFiscalYear" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Year 2</link:label>
    <link:label id="lab_us-gaap_FinancingReceivableExcludingAccruedInterestYearTwoOriginatedFiscalYearBeforeCurrentFiscalYear_label_en-US" xlink:label="lab_us-gaap_FinancingReceivableExcludingAccruedInterestYearTwoOriginatedFiscalYearBeforeCurrentFiscalYear" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Financing Receivable, Excluding Accrued Interest, Year Two, Originated, Fiscal Year before Current Fiscal Year</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinancingReceivableExcludingAccruedInterestYearTwoOriginatedFiscalYearBeforeCurrentFiscalYear" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_FinancingReceivableExcludingAccruedInterestYearTwoOriginatedFiscalYearBeforeCurrentFiscalYear"/>
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    <link:label id="lab_slm_NetUnamortizedPremiumOrDiscountOriginatedInFiscalYearBeforeLatestFiscalYear_dfab8f59-437e-4b89-89e3-cbd2aa05063e_terseLabel_en-US" xlink:label="lab_slm_NetUnamortizedPremiumOrDiscountOriginatedInFiscalYearBeforeLatestFiscalYear" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Private Education Loans deferred origination costs and unamortized premium/(discount), Year 2</link:label>
    <link:label id="lab_slm_NetUnamortizedPremiumOrDiscountOriginatedInFiscalYearBeforeLatestFiscalYear_label_en-US" xlink:label="lab_slm_NetUnamortizedPremiumOrDiscountOriginatedInFiscalYearBeforeLatestFiscalYear" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Net Unamortized Premium Or Discount, Originated In Fiscal Year Before Latest Fiscal Year</link:label>
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    <link:label id="lab_slm_LoansGrossOriginatedFiveYearsBeforeLatestFiscalYear_8879d8a9-d8a4-4e7d-b57b-5b9bb0d2896d_terseLabel_en-US" xlink:label="lab_slm_LoansGrossOriginatedFiveYearsBeforeLatestFiscalYear" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Total Private Education Loans, gross, After Year 5</link:label>
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    <link:label id="lab_slm_FinancingReceivableLoansInForbearanceYearThreeOriginatedTwoYearsBeforeCurrentFiscalYear_9947fc99-5b83-4258-9e84-132964ce5233_terseLabel_en-US" xlink:label="lab_slm_FinancingReceivableLoansInForbearanceYearThreeOriginatedTwoYearsBeforeCurrentFiscalYear" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Total Private Education Loans in forbearance, Year 3</link:label>
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    <link:label id="lab_us-gaap_Goodwill_78d62160-4af0-43d7-9e82-b9a55b0de397_terseLabel_en-US" xlink:label="lab_us-gaap_Goodwill" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Goodwill</link:label>
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    <link:label id="lab_slm_LoansInRepaymentOriginatedFiveOrMoreYearsBeforeCurrentFiscalYear_1782fb5b-6e25-4cf5-902a-56569ee9cd28_terseLabel_en-US" xlink:label="lab_slm_LoansInRepaymentOriginatedFiveOrMoreYearsBeforeCurrentFiscalYear" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Total Private Education Loans in forbearance, After Year 5</link:label>
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    <link:label id="lab_slm_NitroCollegeMember_e92a8121-dba0-4bdf-bb96-3a49ff5d5e66_terseLabel_en-US" xlink:label="lab_slm_NitroCollegeMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Nitro</link:label>
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    <link:label id="lab_us-gaap_FinancingReceivableCollectivelyEvaluatedForImpairment_057c031d-ba89-4cc1-9099-e481c3f37b0c_terseLabel_en-US" xlink:label="lab_us-gaap_FinancingReceivableCollectivelyEvaluatedForImpairment" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Ending balance: collectively evaluated for impairment</link:label>
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    <link:label id="lab_us-gaap_IncomeTaxReceivable_949fdfb3-d089-4c04-abfa-a0da8b493228_verboseLabel_en-US" xlink:label="lab_us-gaap_IncomeTaxReceivable" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Income taxes receivable, net</link:label>
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    <link:label id="lab_us-gaap_IncomeTaxExpenseBenefit_48be2fde-65d7-4e8b-a00b-577de52ca14a_terseLabel_en-US" xlink:label="lab_us-gaap_IncomeTaxExpenseBenefit" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Income tax expense</link:label>
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    <link:label id="lab_us-gaap_SeriesBPreferredStockMember_e5f3bf9f-e388-466d-8d45-dd3d9f49d108_terseLabel_en-US" xlink:label="lab_us-gaap_SeriesBPreferredStockMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Series B Preferred Stock</link:label>
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    <link:label id="lab_us-gaap_DerivativeLiabilities_c3232b8c-27ac-4029-ad77-8bae99ed6a1e_negatedLabel_en-US" xlink:label="lab_us-gaap_DerivativeLiabilities" xlink:role="http://www.xbrl.org/2009/role/negatedLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Derivative liabilities</link:label>
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    <link:label id="lab_us-gaap_DerivativeLiabilities_label_en-US" xlink:label="lab_us-gaap_DerivativeLiabilities" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Derivative Liability</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeLiabilities" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_DerivativeLiabilities"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_DerivativeLiabilities" xlink:to="lab_us-gaap_DerivativeLiabilities" xlink:type="arc" order="1"/>
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    <link:label id="lab_us-gaap_HedgedAssetFairValueHedgeCumulativeIncreaseDecrease_label_en-US" xlink:label="lab_us-gaap_HedgedAssetFairValueHedgeCumulativeIncreaseDecrease" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Hedged Asset, Fair Value Hedge, Cumulative Increase (Decrease)</link:label>
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    <link:label id="lab_us-gaap_DerivativeFairValueOfDerivativeLiability_label_en-US" xlink:label="lab_us-gaap_DerivativeFairValueOfDerivativeLiability" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Derivative Liability, Subject to Master Netting Arrangement, before Offset</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeFairValueOfDerivativeLiability" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_DerivativeFairValueOfDerivativeLiability"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_DerivativeFairValueOfDerivativeLiability" xlink:to="lab_us-gaap_DerivativeFairValueOfDerivativeLiability" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_PreferredStockDividendRatePerDollarAmount_4a6d5cbc-f020-4929-9f64-817241da2c66_terseLabel_en-US" xlink:label="lab_us-gaap_PreferredStockDividendRatePerDollarAmount" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Preferred stock dividend rate (in dollars per share)</link:label>
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    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PreferredStockDividendRatePerDollarAmount" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_PreferredStockDividendRatePerDollarAmount"/>
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    <link:label id="lab_us-gaap_TimeDepositMaturitiesRollingYearFive_74446053-74d8-475b-9a08-f7d04a53386d_terseLabel_en-US" xlink:label="lab_us-gaap_TimeDepositMaturitiesRollingYearFive" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">After four years to five years</link:label>
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    <link:label id="lab_slm_Maturity2039Member_49b86031-f6d1-4826-87bd-fd200be6a40c_terseLabel_en-US" xlink:label="lab_slm_Maturity2039Member" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">2039</link:label>
    <link:label id="lab_slm_Maturity2039Member_label_en-US" xlink:label="lab_slm_Maturity2039Member" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Maturity 2039 [Member]</link:label>
    <link:label id="lab_slm_Maturity2039Member_documentation_en-US" xlink:label="lab_slm_Maturity2039Member" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Maturity 2039 [Member]</link:label>
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    <link:label id="lab_us-gaap_Investments_1fcb7a05-fef3-472a-a7dd-8ddca5c4ac44_totalLabel_en-US" xlink:label="lab_us-gaap_Investments" xlink:role="http://www.xbrl.org/2003/role/totalLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Total investments</link:label>
    <link:label id="lab_us-gaap_Investments_label_en-US" xlink:label="lab_us-gaap_Investments" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Investments</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_Investments" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_Investments"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_Investments" xlink:to="lab_us-gaap_Investments" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_FairValueDisclosureOffbalanceSheetRisksAmountLiability_8680323c-1770-4664-9b87-1000a102d731_periodStartLabel_en-US" xlink:label="lab_us-gaap_FairValueDisclosureOffbalanceSheetRisksAmountLiability" xlink:role="http://www.xbrl.org/2003/role/periodStartLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Beginning balance</link:label>
    <link:label id="lab_us-gaap_FairValueDisclosureOffbalanceSheetRisksAmountLiability_f7980e80-532e-44f3-bbcb-cad10091c294_periodEndLabel_en-US" xlink:label="lab_us-gaap_FairValueDisclosureOffbalanceSheetRisksAmountLiability" xlink:role="http://www.xbrl.org/2003/role/periodEndLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Ending balance</link:label>
    <link:label id="lab_us-gaap_FairValueDisclosureOffbalanceSheetRisksAmountLiability_label_en-US" xlink:label="lab_us-gaap_FairValueDisclosureOffbalanceSheetRisksAmountLiability" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Fair Value Disclosure, off-Balance-Sheet Risks, Amount, Liability</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueDisclosureOffbalanceSheetRisksAmountLiability" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_FairValueDisclosureOffbalanceSheetRisksAmountLiability"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_FairValueDisclosureOffbalanceSheetRisksAmountLiability" xlink:to="lab_us-gaap_FairValueDisclosureOffbalanceSheetRisksAmountLiability" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_CommonStockValue_a99d5445-216a-45a8-9d0d-5818fef15665_terseLabel_en-US" xlink:label="lab_us-gaap_CommonStockValue" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Common stock, par value $0.20 per share, 1.125 billion shares authorized: 437.6&#160;million and 435.1 million shares issued, respectively</link:label>
    <link:label id="lab_us-gaap_CommonStockValue_label_en-US" xlink:label="lab_us-gaap_CommonStockValue" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Common Stock, Value, Issued</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockValue" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_CommonStockValue"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_CommonStockValue" xlink:to="lab_us-gaap_CommonStockValue" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_TierOneRiskBasedCapitalRequiredToBeWellCapitalized_2de26ebe-92dd-4b36-9aa2-d86fa7e1b1ff_terseLabel_en-US" xlink:label="lab_us-gaap_TierOneRiskBasedCapitalRequiredToBeWellCapitalized" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Tier 1 Capital (to Risk-Weighted Assets)</link:label>
    <link:label id="lab_us-gaap_TierOneRiskBasedCapitalRequiredToBeWellCapitalized_label_en-US" xlink:label="lab_us-gaap_TierOneRiskBasedCapitalRequiredToBeWellCapitalized" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Banking Regulation, Tier 1 Risk-Based Capital, Well Capitalized, Minimum</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_TierOneRiskBasedCapitalRequiredToBeWellCapitalized" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_TierOneRiskBasedCapitalRequiredToBeWellCapitalized"/>
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    <link:label id="lab_us-gaap_DebtInstrumentNameDomain_5d5a8edf-c5c0-4eb6-bb99-64afa15ca39a_terseLabel_en-US" xlink:label="lab_us-gaap_DebtInstrumentNameDomain" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Debt Instrument, Name [Domain]</link:label>
    <link:label id="lab_us-gaap_DebtInstrumentNameDomain_label_en-US" xlink:label="lab_us-gaap_DebtInstrumentNameDomain" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Debt Instrument, Name [Domain]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentNameDomain" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_DebtInstrumentNameDomain"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_DebtInstrumentNameDomain" xlink:to="lab_us-gaap_DebtInstrumentNameDomain" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_BusinessAcquisitionAcquireeDomain_45e1dd66-88c0-4594-827e-0854a07c1d71_terseLabel_en-US" xlink:label="lab_us-gaap_BusinessAcquisitionAcquireeDomain" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Business Acquisition, Acquiree [Domain]</link:label>
    <link:label id="lab_us-gaap_BusinessAcquisitionAcquireeDomain_label_en-US" xlink:label="lab_us-gaap_BusinessAcquisitionAcquireeDomain" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Business Acquisition, Acquiree [Domain]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessAcquisitionAcquireeDomain" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_BusinessAcquisitionAcquireeDomain"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_BusinessAcquisitionAcquireeDomain" xlink:to="lab_us-gaap_BusinessAcquisitionAcquireeDomain" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_FinancingReceivableModificationsPostModificationRecordedInvestment2_a6ebf497-ef23-417d-85dd-2337e9cf41d3_terseLabel_en-US" xlink:label="lab_us-gaap_FinancingReceivableModificationsPostModificationRecordedInvestment2" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Modified Loans</link:label>
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    <link:label id="lab_us-gaap_PreferredStockMember_bbaa4899-b2eb-450c-901b-7c0ae8e7862b_terseLabel_en-US" xlink:label="lab_us-gaap_PreferredStockMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Preferred Stock</link:label>
    <link:label id="lab_us-gaap_PreferredStockMember_label_en-US" xlink:label="lab_us-gaap_PreferredStockMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Preferred Stock [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PreferredStockMember" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_PreferredStockMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_PreferredStockMember" xlink:to="lab_us-gaap_PreferredStockMember" xlink:type="arc" order="1"/>
    <link:label id="lab_slm_FloatingRateNonCumulativePreferredStockSeriesBParValue20PerShareMember_261f0dee-f575-4c6a-a98a-d705444af5ad_terseLabel_en-US" xlink:label="lab_slm_FloatingRateNonCumulativePreferredStockSeriesBParValue20PerShareMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Floating Rate Non-Cumulative Preferred Stock, Series B, par value $.20 per share</link:label>
    <link:label id="lab_slm_FloatingRateNonCumulativePreferredStockSeriesBParValue20PerShareMember_label_en-US" xlink:label="lab_slm_FloatingRateNonCumulativePreferredStockSeriesBParValue20PerShareMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Floating Rate Non-Cumulative Preferred Stock, Series B, par value $.20 per share [Member]</link:label>
    <link:label id="lab_slm_FloatingRateNonCumulativePreferredStockSeriesBParValue20PerShareMember_documentation_en-US" xlink:label="lab_slm_FloatingRateNonCumulativePreferredStockSeriesBParValue20PerShareMember" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Floating Rate Non-Cumulative Preferred Stock, Series B, par value $.20 per share</link:label>
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    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_slm_FloatingRateNonCumulativePreferredStockSeriesBParValue20PerShareMember" xlink:to="lab_slm_FloatingRateNonCumulativePreferredStockSeriesBParValue20PerShareMember" xlink:type="arc" order="1"/>
    <link:label id="lab_slm_EstimatedWeightedAverageLifeOfStudentLoans_ab5a63ae-186e-4030-bb00-cae60ee149cb_terseLabel_en-US" xlink:label="lab_slm_EstimatedWeightedAverageLifeOfStudentLoans" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Estimated weighted average life of student loans</link:label>
    <link:label id="lab_slm_EstimatedWeightedAverageLifeOfStudentLoans_label_en-US" xlink:label="lab_slm_EstimatedWeightedAverageLifeOfStudentLoans" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Estimated Weighted Average Life Of Student Loans</link:label>
    <link:label id="lab_slm_EstimatedWeightedAverageLifeOfStudentLoans_documentation_en-US" xlink:label="lab_slm_EstimatedWeightedAverageLifeOfStudentLoans" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Estimated weighted average life of student loans.</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_slm_EstimatedWeightedAverageLifeOfStudentLoans" xlink:href="slm-20230331.xsd#slm_EstimatedWeightedAverageLifeOfStudentLoans"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_slm_EstimatedWeightedAverageLifeOfStudentLoans" xlink:to="lab_slm_EstimatedWeightedAverageLifeOfStudentLoans" xlink:type="arc" order="1"/>
    <link:label id="lab_slm_FinancingReceivableCreditLossExpenseReversalNewCommitments_4003ae5f-8dd9-46cd-9460-471b328016a7_terseLabel_en-US" xlink:label="lab_slm_FinancingReceivableCreditLossExpenseReversalNewCommitments" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Provisions for loan losses</link:label>
    <link:label id="lab_slm_FinancingReceivableCreditLossExpenseReversalNewCommitments_label_en-US" xlink:label="lab_slm_FinancingReceivableCreditLossExpenseReversalNewCommitments" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Financing Receivable, Credit Loss, Expense (Reversal), New Commitments</link:label>
    <link:label id="lab_slm_FinancingReceivableCreditLossExpenseReversalNewCommitments_documentation_en-US" xlink:label="lab_slm_FinancingReceivableCreditLossExpenseReversalNewCommitments" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Financing Receivable, Credit Loss, Expense (Reversal), New Commitments</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_slm_FinancingReceivableCreditLossExpenseReversalNewCommitments" xlink:href="slm-20230331.xsd#slm_FinancingReceivableCreditLossExpenseReversalNewCommitments"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_slm_FinancingReceivableCreditLossExpenseReversalNewCommitments" xlink:to="lab_slm_FinancingReceivableCreditLossExpenseReversalNewCommitments" xlink:type="arc" order="1"/>
    <link:label id="lab_slm_FinancingReceivableAfterAllowanceForCreditLossOriginatedThreeYearsBeforeCurrentFiscalYear_72779497-c866-46c1-a87a-cf5ee9f56013_terseLabel_en-US" xlink:label="lab_slm_FinancingReceivableAfterAllowanceForCreditLossOriginatedThreeYearsBeforeCurrentFiscalYear" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Private Education Loans, net, Year 4</link:label>
    <link:label id="lab_slm_FinancingReceivableAfterAllowanceForCreditLossOriginatedThreeYearsBeforeCurrentFiscalYear_label_en-US" xlink:label="lab_slm_FinancingReceivableAfterAllowanceForCreditLossOriginatedThreeYearsBeforeCurrentFiscalYear" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Financing Receivable, after Allowance for Credit Loss, Originated Three Years Before Current Fiscal Year</link:label>
    <link:label id="lab_slm_FinancingReceivableAfterAllowanceForCreditLossOriginatedThreeYearsBeforeCurrentFiscalYear_documentation_en-US" xlink:label="lab_slm_FinancingReceivableAfterAllowanceForCreditLossOriginatedThreeYearsBeforeCurrentFiscalYear" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Financing Receivable, after Allowance for Credit Loss, Originated Three Years Before Current Fiscal Year</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_slm_FinancingReceivableAfterAllowanceForCreditLossOriginatedThreeYearsBeforeCurrentFiscalYear" xlink:href="slm-20230331.xsd#slm_FinancingReceivableAfterAllowanceForCreditLossOriginatedThreeYearsBeforeCurrentFiscalYear"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_slm_FinancingReceivableAfterAllowanceForCreditLossOriginatedThreeYearsBeforeCurrentFiscalYear" xlink:to="lab_slm_FinancingReceivableAfterAllowanceForCreditLossOriginatedThreeYearsBeforeCurrentFiscalYear" xlink:type="arc" order="1"/>
    <link:label id="lab_slm_FinancingReceivableAccruedInterestOriginationVintageOriginatedThreeYearsBeforeLatestFiscalYear_384f7db2-f7e3-4246-a54e-a7c2dbdb9f1a_terseLabel_en-US" xlink:label="lab_slm_FinancingReceivableAccruedInterestOriginationVintageOriginatedThreeYearsBeforeLatestFiscalYear" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Total accrued interest by origination vintage, Year 4</link:label>
    <link:label id="lab_slm_FinancingReceivableAccruedInterestOriginationVintageOriginatedThreeYearsBeforeLatestFiscalYear_label_en-US" xlink:label="lab_slm_FinancingReceivableAccruedInterestOriginationVintageOriginatedThreeYearsBeforeLatestFiscalYear" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Financing Receivable, Accrued interest, Origination Vintage, Originated Three Years before Latest Fiscal Year</link:label>
    <link:label id="lab_slm_FinancingReceivableAccruedInterestOriginationVintageOriginatedThreeYearsBeforeLatestFiscalYear_documentation_en-US" xlink:label="lab_slm_FinancingReceivableAccruedInterestOriginationVintageOriginatedThreeYearsBeforeLatestFiscalYear" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Financing Receivable, Accrued interest, Origination Vintage, Originated Three Years before Latest Fiscal Year</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_slm_FinancingReceivableAccruedInterestOriginationVintageOriginatedThreeYearsBeforeLatestFiscalYear" xlink:href="slm-20230331.xsd#slm_FinancingReceivableAccruedInterestOriginationVintageOriginatedThreeYearsBeforeLatestFiscalYear"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_slm_FinancingReceivableAccruedInterestOriginationVintageOriginatedThreeYearsBeforeLatestFiscalYear" xlink:to="lab_slm_FinancingReceivableAccruedInterestOriginationVintageOriginatedThreeYearsBeforeLatestFiscalYear" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_TierOneLeverageCapitalRequiredToBeWellCapitalized_6bc599e9-2d09-44a3-a650-cc8d71c90247_terseLabel_en-US" xlink:label="lab_us-gaap_TierOneLeverageCapitalRequiredToBeWellCapitalized" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Tier 1 Capital (to Average Assets)</link:label>
    <link:label id="lab_us-gaap_TierOneLeverageCapitalRequiredToBeWellCapitalized_label_en-US" xlink:label="lab_us-gaap_TierOneLeverageCapitalRequiredToBeWellCapitalized" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Banking Regulation, Tier 1 Leverage Capital, Well Capitalized, Minimum</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_TierOneLeverageCapitalRequiredToBeWellCapitalized" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_TierOneLeverageCapitalRequiredToBeWellCapitalized"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_TierOneLeverageCapitalRequiredToBeWellCapitalized" xlink:to="lab_us-gaap_TierOneLeverageCapitalRequiredToBeWellCapitalized" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_8ef9c6ff-5788-4014-9a7f-7e5072ca6be3_periodStartLabel_en-US" xlink:label="lab_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents" xlink:role="http://www.xbrl.org/2003/role/periodStartLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Cash, cash equivalents and restricted cash at beginning of period</link:label>
    <link:label id="lab_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_0faef751-2f18-486f-925e-498caf171783_periodEndLabel_en-US" xlink:label="lab_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents" xlink:role="http://www.xbrl.org/2003/role/periodEndLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Cash, cash equivalents and restricted cash at end of period</link:label>
    <link:label id="lab_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_0e924d8a-7681-426b-8185-9fb60d83413f_totalLabel_en-US" xlink:label="lab_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents" xlink:role="http://www.xbrl.org/2003/role/totalLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Total cash, cash equivalents and restricted cash</link:label>
    <link:label id="lab_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_label_en-US" xlink:label="lab_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Cash, Cash Equivalents, Restricted Cash, and Restricted Cash Equivalents</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents" xlink:to="lab_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents" xlink:type="arc" order="1"/>
    <link:label id="lab_slm_CarryingAmountOfAssetsSecuringDebtOutstandingLoans_159c2aab-d763-424e-b50a-f6844028a82d_terseLabel_en-US" xlink:label="lab_slm_CarryingAmountOfAssetsSecuringDebtOutstandingLoans" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Loans</link:label>
    <link:label id="lab_slm_CarryingAmountOfAssetsSecuringDebtOutstandingLoans_label_en-US" xlink:label="lab_slm_CarryingAmountOfAssetsSecuringDebtOutstandingLoans" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Carrying Amount Of Assets Securing Debt Outstanding Loans</link:label>
    <link:label id="lab_slm_CarryingAmountOfAssetsSecuringDebtOutstandingLoans_documentation_en-US" xlink:label="lab_slm_CarryingAmountOfAssetsSecuringDebtOutstandingLoans" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Carrying Amount Of Assets Securing Debt Outstanding Loans</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_slm_CarryingAmountOfAssetsSecuringDebtOutstandingLoans" xlink:href="slm-20230331.xsd#slm_CarryingAmountOfAssetsSecuringDebtOutstandingLoans"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_slm_CarryingAmountOfAssetsSecuringDebtOutstandingLoans" xlink:to="lab_slm_CarryingAmountOfAssetsSecuringDebtOutstandingLoans" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_FederalFamilyEducationLoanProgramFfelpGuaranteedLoansMember_ebc977fb-d4e8-4dfb-a383-895aacfc31a1_terseLabel_en-US" xlink:label="lab_us-gaap_FederalFamilyEducationLoanProgramFfelpGuaranteedLoansMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">FFELP Loans</link:label>
    <link:label id="lab_us-gaap_FederalFamilyEducationLoanProgramFfelpGuaranteedLoansMember_0b479a34-ce7e-4481-bcb8-5f75eaeaa84e_verboseLabel_en-US" xlink:label="lab_us-gaap_FederalFamilyEducationLoanProgramFfelpGuaranteedLoansMember" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">FFELP Loans</link:label>
    <link:label id="lab_us-gaap_FederalFamilyEducationLoanProgramFfelpGuaranteedLoansMember_label_en-US" xlink:label="lab_us-gaap_FederalFamilyEducationLoanProgramFfelpGuaranteedLoansMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Federal Family Education Loan Program (FFELP) Guaranteed Loans [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FederalFamilyEducationLoanProgramFfelpGuaranteedLoansMember" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_FederalFamilyEducationLoanProgramFfelpGuaranteedLoansMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_FederalFamilyEducationLoanProgramFfelpGuaranteedLoansMember" xlink:to="lab_us-gaap_FederalFamilyEducationLoanProgramFfelpGuaranteedLoansMember" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_ProceedsFromIssuanceOfUnsecuredDebt_b90dbf81-68a7-40e5-a440-bf5ea60a76e5_terseLabel_en-US" xlink:label="lab_us-gaap_ProceedsFromIssuanceOfUnsecuredDebt" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Unsecured debt issued</link:label>
    <link:label id="lab_us-gaap_ProceedsFromIssuanceOfUnsecuredDebt_label_en-US" xlink:label="lab_us-gaap_ProceedsFromIssuanceOfUnsecuredDebt" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Proceeds from Issuance of Unsecured Debt</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProceedsFromIssuanceOfUnsecuredDebt" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ProceedsFromIssuanceOfUnsecuredDebt"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_ProceedsFromIssuanceOfUnsecuredDebt" xlink:to="lab_us-gaap_ProceedsFromIssuanceOfUnsecuredDebt" xlink:type="arc" order="1"/>
    <link:label id="lab_slm_FinancingReceivableAllowanceForCreditLossWriteoffAfterRecoveryOriginatedFourYearsBeforeCurrentFiscalYear_2541397a-cf63-45a2-a76b-0462fe62c7ac_negatedTerseLabel_en-US" xlink:label="lab_slm_FinancingReceivableAllowanceForCreditLossWriteoffAfterRecoveryOriginatedFourYearsBeforeCurrentFiscalYear" xlink:role="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Current period recoveries, Year 5</link:label>
    <link:label id="lab_slm_FinancingReceivableAllowanceForCreditLossWriteoffAfterRecoveryOriginatedFourYearsBeforeCurrentFiscalYear_label_en-US" xlink:label="lab_slm_FinancingReceivableAllowanceForCreditLossWriteoffAfterRecoveryOriginatedFourYearsBeforeCurrentFiscalYear" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Financing Receivable, Allowance for Credit Loss, Writeoff, after Recovery, Originated Four Years Before Current Fiscal Year</link:label>
    <link:label id="lab_slm_FinancingReceivableAllowanceForCreditLossWriteoffAfterRecoveryOriginatedFourYearsBeforeCurrentFiscalYear_documentation_en-US" xlink:label="lab_slm_FinancingReceivableAllowanceForCreditLossWriteoffAfterRecoveryOriginatedFourYearsBeforeCurrentFiscalYear" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Financing Receivable, Allowance for Credit Loss, Writeoff, after Recovery, Originated Four Years Before Current Fiscal Year</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_slm_FinancingReceivableAllowanceForCreditLossWriteoffAfterRecoveryOriginatedFourYearsBeforeCurrentFiscalYear" xlink:href="slm-20230331.xsd#slm_FinancingReceivableAllowanceForCreditLossWriteoffAfterRecoveryOriginatedFourYearsBeforeCurrentFiscalYear"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_slm_FinancingReceivableAllowanceForCreditLossWriteoffAfterRecoveryOriginatedFourYearsBeforeCurrentFiscalYear" xlink:to="lab_slm_FinancingReceivableAllowanceForCreditLossWriteoffAfterRecoveryOriginatedFourYearsBeforeCurrentFiscalYear" xlink:type="arc" order="1"/>
    <link:label id="lab_slm_FinancingReceivableLoansInForbearanceBeforeAllowanceForCreditLoss_6c6e8c82-2224-4d94-b2a5-d7e53e6aa88d_totalLabel_en-US" xlink:label="lab_slm_FinancingReceivableLoansInForbearanceBeforeAllowanceForCreditLoss" xlink:role="http://www.xbrl.org/2003/role/totalLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Total Private Education Loans in forbearance</link:label>
    <link:label id="lab_slm_FinancingReceivableLoansInForbearanceBeforeAllowanceForCreditLoss_label_en-US" xlink:label="lab_slm_FinancingReceivableLoansInForbearanceBeforeAllowanceForCreditLoss" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Financing Receivable, Loans In Forbearance, before Allowance for Credit Loss</link:label>
    <link:label id="lab_slm_FinancingReceivableLoansInForbearanceBeforeAllowanceForCreditLoss_documentation_en-US" xlink:label="lab_slm_FinancingReceivableLoansInForbearanceBeforeAllowanceForCreditLoss" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Financing Receivable, Loans In Forbearance, before Allowance for Credit Loss</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_slm_FinancingReceivableLoansInForbearanceBeforeAllowanceForCreditLoss" xlink:href="slm-20230331.xsd#slm_FinancingReceivableLoansInForbearanceBeforeAllowanceForCreditLoss"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_slm_FinancingReceivableLoansInForbearanceBeforeAllowanceForCreditLoss" xlink:to="lab_slm_FinancingReceivableLoansInForbearanceBeforeAllowanceForCreditLoss" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeMember_d3585d02-710a-4a9f-b6b9-1a36eb60c75e_terseLabel_en-US" xlink:label="lab_us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Reclassification out of Accumulated Other Comprehensive Income</link:label>
    <link:label id="lab_us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeMember_label_en-US" xlink:label="lab_us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Reclassification out of Accumulated Other Comprehensive Income [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeMember" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeMember" xlink:to="lab_us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeMember" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_DerivativeAssetsAbstract_ee8beba8-c136-4142-84f2-6e96af7b7145_terseLabel_en-US" xlink:label="lab_us-gaap_DerivativeAssetsAbstract" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Other Assets</link:label>
    <link:label id="lab_us-gaap_DerivativeAssetsAbstract_label_en-US" xlink:label="lab_us-gaap_DerivativeAssetsAbstract" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Derivative Asset [Abstract]</link:label>
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    <link:label id="lab_us-gaap_OtherComprehensiveIncomeLossNetOfTax_20a1a7f8-3339-412f-9f6e-dbb4ea980507_totalLabel_en-US" xlink:label="lab_us-gaap_OtherComprehensiveIncomeLossNetOfTax" xlink:role="http://www.xbrl.org/2003/role/totalLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Other comprehensive income (loss), net of tax (expense) benefit</link:label>
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    <link:label id="lab_slm_FinancingReceivableTemporaryInterestRateReductionFinancialDifficultyStatus_ef61965a-559e-473e-b25d-2db0be1aaac4_terseLabel_en-US" xlink:label="lab_slm_FinancingReceivableTemporaryInterestRateReductionFinancialDifficultyStatus" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Interest rate offered to borrowers facing financial difficulty</link:label>
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    <link:label id="lab_us-gaap_PreferredStockDividendsIncomeStatementImpact_a6756585-13ea-4247-87d7-a6a39a5848fd_terseLabel_en-US" xlink:label="lab_us-gaap_PreferredStockDividendsIncomeStatementImpact" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Preferred stock dividends</link:label>
    <link:label id="lab_us-gaap_PreferredStockDividendsIncomeStatementImpact_label_en-US" xlink:label="lab_us-gaap_PreferredStockDividendsIncomeStatementImpact" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Preferred Stock Dividends, Income Statement Impact</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PreferredStockDividendsIncomeStatementImpact" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_PreferredStockDividendsIncomeStatementImpact"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_PreferredStockDividendsIncomeStatementImpact" xlink:to="lab_us-gaap_PreferredStockDividendsIncomeStatementImpact" xlink:type="arc" order="1"/>
    <link:label id="lab_slm_Maturity2055Member_a39e7deb-e5fd-4c9a-90f4-12d941d4a87e_terseLabel_en-US" xlink:label="lab_slm_Maturity2055Member" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">2055</link:label>
    <link:label id="lab_slm_Maturity2055Member_label_en-US" xlink:label="lab_slm_Maturity2055Member" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Maturity 2055 [Member]</link:label>
    <link:label id="lab_slm_Maturity2055Member_documentation_en-US" xlink:label="lab_slm_Maturity2055Member" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Maturity 2055</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_slm_Maturity2055Member" xlink:href="slm-20230331.xsd#slm_Maturity2055Member"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_slm_Maturity2055Member" xlink:to="lab_slm_Maturity2055Member" xlink:type="arc" order="1"/>
    <link:label id="lab_slm_FairValueDisclosureOffBalanceSheetRisksAmountLiabilityCommitmentsFunded_0a4fb5ec-ebe7-4564-89b7-a56bf9e7fe58_negatedTerseLabel_en-US" xlink:label="lab_slm_FairValueDisclosureOffBalanceSheetRisksAmountLiabilityCommitmentsFunded" xlink:role="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Transfer - funded loans</link:label>
    <link:label id="lab_slm_FairValueDisclosureOffBalanceSheetRisksAmountLiabilityCommitmentsFunded_label_en-US" xlink:label="lab_slm_FairValueDisclosureOffBalanceSheetRisksAmountLiabilityCommitmentsFunded" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Fair Value Disclosure, Off-balance Sheet Risks, Amount, Liability, Commitments Funded</link:label>
    <link:label id="lab_slm_FairValueDisclosureOffBalanceSheetRisksAmountLiabilityCommitmentsFunded_documentation_en-US" xlink:label="lab_slm_FairValueDisclosureOffBalanceSheetRisksAmountLiabilityCommitmentsFunded" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Fair Value Disclosure, Off-balance Sheet Risks, Amount, Liability, Commitments Funded</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_slm_FairValueDisclosureOffBalanceSheetRisksAmountLiabilityCommitmentsFunded" xlink:href="slm-20230331.xsd#slm_FairValueDisclosureOffBalanceSheetRisksAmountLiabilityCommitmentsFunded"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_slm_FairValueDisclosureOffBalanceSheetRisksAmountLiabilityCommitmentsFunded" xlink:to="lab_slm_FairValueDisclosureOffBalanceSheetRisksAmountLiabilityCommitmentsFunded" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_IntangibleAssetsNetIncludingGoodwill_06f4ea77-c6a9-4999-a61f-54221205bb80_terseLabel_en-US" xlink:label="lab_us-gaap_IntangibleAssetsNetIncludingGoodwill" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Goodwill and acquired intangible assets, net</link:label>
    <link:label id="lab_us-gaap_IntangibleAssetsNetIncludingGoodwill_label_en-US" xlink:label="lab_us-gaap_IntangibleAssetsNetIncludingGoodwill" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Intangible Assets, Net (Including Goodwill)</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IntangibleAssetsNetIncludingGoodwill" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_IntangibleAssetsNetIncludingGoodwill"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_IntangibleAssetsNetIncludingGoodwill" xlink:to="lab_us-gaap_IntangibleAssetsNetIncludingGoodwill" xlink:type="arc" order="1"/>
    <link:label id="lab_slm_SeasoningBasedOnMonthlyScheduledPaymentsDueFromOneToTwelvePaymentsMember_6e7255b8-676f-4305-b605-522689768f07_terseLabel_en-US" xlink:label="lab_slm_SeasoningBasedOnMonthlyScheduledPaymentsDueFromOneToTwelvePaymentsMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">1-12 payments</link:label>
    <link:label id="lab_slm_SeasoningBasedOnMonthlyScheduledPaymentsDueFromOneToTwelvePaymentsMember_label_en-US" xlink:label="lab_slm_SeasoningBasedOnMonthlyScheduledPaymentsDueFromOneToTwelvePaymentsMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Seasoning Based On Monthly Scheduled Payments Due From One To Twelve Payments [Member]</link:label>
    <link:label id="lab_slm_SeasoningBasedOnMonthlyScheduledPaymentsDueFromOneToTwelvePaymentsMember_documentation_en-US" xlink:label="lab_slm_SeasoningBasedOnMonthlyScheduledPaymentsDueFromOneToTwelvePaymentsMember" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Seasoning Based On Monthly Scheduled Payments Due From One To Twelve Payments [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_slm_SeasoningBasedOnMonthlyScheduledPaymentsDueFromOneToTwelvePaymentsMember" xlink:href="slm-20230331.xsd#slm_SeasoningBasedOnMonthlyScheduledPaymentsDueFromOneToTwelvePaymentsMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_slm_SeasoningBasedOnMonthlyScheduledPaymentsDueFromOneToTwelvePaymentsMember" xlink:to="lab_slm_SeasoningBasedOnMonthlyScheduledPaymentsDueFromOneToTwelvePaymentsMember" xlink:type="arc" order="1"/>
    <link:label id="lab_dei_EntityIncorporationStateCountryCode_b7d93f37-785d-43e2-8b2c-63d5a7fbfef5_terseLabel_en-US" xlink:label="lab_dei_EntityIncorporationStateCountryCode" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Entity Incorporation, State or Country Code</link:label>
    <link:label id="lab_dei_EntityIncorporationStateCountryCode_label_en-US" xlink:label="lab_dei_EntityIncorporationStateCountryCode" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Entity Incorporation, State or Country Code</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityIncorporationStateCountryCode" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_EntityIncorporationStateCountryCode"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_dei_EntityIncorporationStateCountryCode" xlink:to="lab_dei_EntityIncorporationStateCountryCode" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_DerivativeFairValueOfDerivativeAssetAmountOffsetAgainstCollateral_53741ef1-bc77-46e7-8ee9-cfb3a69cac1e_totalLabel_en-US" xlink:label="lab_us-gaap_DerivativeFairValueOfDerivativeAssetAmountOffsetAgainstCollateral" xlink:role="http://www.xbrl.org/2003/role/totalLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Net position</link:label>
    <link:label id="lab_us-gaap_DerivativeFairValueOfDerivativeAssetAmountOffsetAgainstCollateral_label_en-US" xlink:label="lab_us-gaap_DerivativeFairValueOfDerivativeAssetAmountOffsetAgainstCollateral" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Derivative Asset, Including Not Subject to Master Netting Arrangement, after Offset and Deduction</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeFairValueOfDerivativeAssetAmountOffsetAgainstCollateral" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_DerivativeFairValueOfDerivativeAssetAmountOffsetAgainstCollateral"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_DerivativeFairValueOfDerivativeAssetAmountOffsetAgainstCollateral" xlink:to="lab_us-gaap_DerivativeFairValueOfDerivativeAssetAmountOffsetAgainstCollateral" xlink:type="arc" order="1"/>
    <link:label id="lab_slm_FinancingReceivableAllowanceForCreditLossExcludingAccruedInterestWriteoffOriginatedFourYearsBeforeLatestFiscalYear_693cfa9f-262c-4fce-b334-9365c6c4e462_negatedTerseLabel_en-US" xlink:label="lab_slm_FinancingReceivableAllowanceForCreditLossExcludingAccruedInterestWriteoffOriginatedFourYearsBeforeLatestFiscalYear" xlink:role="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Current period gross charge-offs, Year 5</link:label>
    <link:label id="lab_slm_FinancingReceivableAllowanceForCreditLossExcludingAccruedInterestWriteoffOriginatedFourYearsBeforeLatestFiscalYear_label_en-US" xlink:label="lab_slm_FinancingReceivableAllowanceForCreditLossExcludingAccruedInterestWriteoffOriginatedFourYearsBeforeLatestFiscalYear" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Financing Receivable, Allowance for Credit Loss, Excluding Accrued Interest, Writeoff, Originated Four Years Before Latest Fiscal Year</link:label>
    <link:label id="lab_slm_FinancingReceivableAllowanceForCreditLossExcludingAccruedInterestWriteoffOriginatedFourYearsBeforeLatestFiscalYear_documentation_en-US" xlink:label="lab_slm_FinancingReceivableAllowanceForCreditLossExcludingAccruedInterestWriteoffOriginatedFourYearsBeforeLatestFiscalYear" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Financing Receivable, Allowance for Credit Loss, Excluding Accrued Interest, Writeoff, Originated Four Years Before Latest Fiscal Year</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_slm_FinancingReceivableAllowanceForCreditLossExcludingAccruedInterestWriteoffOriginatedFourYearsBeforeLatestFiscalYear" xlink:href="slm-20230331.xsd#slm_FinancingReceivableAllowanceForCreditLossExcludingAccruedInterestWriteoffOriginatedFourYearsBeforeLatestFiscalYear"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_slm_FinancingReceivableAllowanceForCreditLossExcludingAccruedInterestWriteoffOriginatedFourYearsBeforeLatestFiscalYear" xlink:to="lab_slm_FinancingReceivableAllowanceForCreditLossExcludingAccruedInterestWriteoffOriginatedFourYearsBeforeLatestFiscalYear" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_LaborAndRelatedExpense_203be518-f8a7-486c-8286-8e6b61a93fa4_terseLabel_en-US" xlink:label="lab_us-gaap_LaborAndRelatedExpense" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Compensation and benefits</link:label>
    <link:label id="lab_us-gaap_LaborAndRelatedExpense_label_en-US" xlink:label="lab_us-gaap_LaborAndRelatedExpense" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Labor and Related Expense</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LaborAndRelatedExpense" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_LaborAndRelatedExpense"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_LaborAndRelatedExpense" xlink:to="lab_us-gaap_LaborAndRelatedExpense" xlink:type="arc" order="1"/>
    <link:label id="lab_slm_LoansInRepaymentOriginatedTwoYearsBeforeCurrentFiscalYear_eb7cc56a-69dd-483d-849b-538f5f73d196_terseLabel_en-US" xlink:label="lab_slm_LoansInRepaymentOriginatedTwoYearsBeforeCurrentFiscalYear" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Total Private Education Loans in forbearance, Year 3</link:label>
    <link:label id="lab_slm_LoansInRepaymentOriginatedTwoYearsBeforeCurrentFiscalYear_label_en-US" xlink:label="lab_slm_LoansInRepaymentOriginatedTwoYearsBeforeCurrentFiscalYear" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Loans In Repayment, Originated Two Years Before Current Fiscal Year</link:label>
    <link:label id="lab_slm_LoansInRepaymentOriginatedTwoYearsBeforeCurrentFiscalYear_documentation_en-US" xlink:label="lab_slm_LoansInRepaymentOriginatedTwoYearsBeforeCurrentFiscalYear" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Loans In Repayment, Originated Two Years Before Current Fiscal Year</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_slm_LoansInRepaymentOriginatedTwoYearsBeforeCurrentFiscalYear" xlink:href="slm-20230331.xsd#slm_LoansInRepaymentOriginatedTwoYearsBeforeCurrentFiscalYear"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_slm_LoansInRepaymentOriginatedTwoYearsBeforeCurrentFiscalYear" xlink:to="lab_slm_LoansInRepaymentOriginatedTwoYearsBeforeCurrentFiscalYear" xlink:type="arc" order="1"/>
    <link:label id="lab_slm_ExcessOfNetAssetFairValueOverCarryingValue_b7e6481c-b4c9-4dd4-97ec-198748b26a17_terseLabel_en-US" xlink:label="lab_slm_ExcessOfNetAssetFairValueOverCarryingValue" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Excess of net asset fair value over carrying value</link:label>
    <link:label id="lab_slm_ExcessOfNetAssetFairValueOverCarryingValue_label_en-US" xlink:label="lab_slm_ExcessOfNetAssetFairValueOverCarryingValue" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Excess Of Net Asset Fair Value Over Carrying Value</link:label>
    <link:label id="lab_slm_ExcessOfNetAssetFairValueOverCarryingValue_documentation_en-US" xlink:label="lab_slm_ExcessOfNetAssetFairValueOverCarryingValue" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Excess of net asset fair value over carrying value.</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_slm_ExcessOfNetAssetFairValueOverCarryingValue" xlink:href="slm-20230331.xsd#slm_ExcessOfNetAssetFairValueOverCarryingValue"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_slm_ExcessOfNetAssetFairValueOverCarryingValue" xlink:to="lab_slm_ExcessOfNetAssetFairValueOverCarryingValue" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_IndustryOfCounterpartyDomain_d6e5be0f-0d6a-4cf3-87b7-7073c516ded3_terseLabel_en-US" xlink:label="lab_us-gaap_IndustryOfCounterpartyDomain" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Industry of Counterparty [Domain]</link:label>
    <link:label id="lab_us-gaap_IndustryOfCounterpartyDomain_label_en-US" xlink:label="lab_us-gaap_IndustryOfCounterpartyDomain" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Industry of Counterparty [Domain]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IndustryOfCounterpartyDomain" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_IndustryOfCounterpartyDomain"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_IndustryOfCounterpartyDomain" xlink:to="lab_us-gaap_IndustryOfCounterpartyDomain" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_CommonStockSharesAuthorized_521bb991-4733-4125-a46a-0122a0dc2737_verboseLabel_en-US" xlink:label="lab_us-gaap_CommonStockSharesAuthorized" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Common stock, shares authorized (in shares)</link:label>
    <link:label id="lab_us-gaap_CommonStockSharesAuthorized_label_en-US" xlink:label="lab_us-gaap_CommonStockSharesAuthorized" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Common Stock, Shares Authorized</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockSharesAuthorized" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_CommonStockSharesAuthorized"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_CommonStockSharesAuthorized" xlink:to="lab_us-gaap_CommonStockSharesAuthorized" xlink:type="arc" order="1"/>
    <link:label id="lab_slm_SeasoningBasedOnMonthlyScheduledPaymentsDueFromMoreThanFortyEightPaymentsInPercent_6862ad69-d22d-4210-9dbf-7a6a4d46c1cc_terseLabel_en-US" xlink:label="lab_slm_SeasoningBasedOnMonthlyScheduledPaymentsDueFromMoreThanFortyEightPaymentsInPercent" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Seasoning based on monthly scheduled payments due from more than 48 payments</link:label>
    <link:label id="lab_slm_SeasoningBasedOnMonthlyScheduledPaymentsDueFromMoreThanFortyEightPaymentsInPercent_label_en-US" xlink:label="lab_slm_SeasoningBasedOnMonthlyScheduledPaymentsDueFromMoreThanFortyEightPaymentsInPercent" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Seasoning Based On Monthly Scheduled Payments Due From More Than Forty Eight Payments In Percent</link:label>
    <link:label id="lab_slm_SeasoningBasedOnMonthlyScheduledPaymentsDueFromMoreThanFortyEightPaymentsInPercent_documentation_en-US" xlink:label="lab_slm_SeasoningBasedOnMonthlyScheduledPaymentsDueFromMoreThanFortyEightPaymentsInPercent" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Seasoning based on monthly scheduled payments due from more than forty eight payments in percent</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_slm_SeasoningBasedOnMonthlyScheduledPaymentsDueFromMoreThanFortyEightPaymentsInPercent" xlink:href="slm-20230331.xsd#slm_SeasoningBasedOnMonthlyScheduledPaymentsDueFromMoreThanFortyEightPaymentsInPercent"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_slm_SeasoningBasedOnMonthlyScheduledPaymentsDueFromMoreThanFortyEightPaymentsInPercent" xlink:to="lab_slm_SeasoningBasedOnMonthlyScheduledPaymentsDueFromMoreThanFortyEightPaymentsInPercent" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_StatementOfIncomeAndComprehensiveIncomeAbstract_7ec240d2-29ba-4b10-b850-857268a1b16f_terseLabel_en-US" xlink:label="lab_us-gaap_StatementOfIncomeAndComprehensiveIncomeAbstract" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Statement of Comprehensive Income [Abstract]</link:label>
    <link:label id="lab_us-gaap_StatementOfIncomeAndComprehensiveIncomeAbstract_label_en-US" xlink:label="lab_us-gaap_StatementOfIncomeAndComprehensiveIncomeAbstract" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Statement of Comprehensive Income [Abstract]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementOfIncomeAndComprehensiveIncomeAbstract" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_StatementOfIncomeAndComprehensiveIncomeAbstract"/>
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    <link:label id="lab_srt_MaximumMember_label_en-US" xlink:label="lab_srt_MaximumMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Maximum [Member]</link:label>
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    <link:label id="lab_us-gaap_FinancingReceivableModificationsSubsequentDefaultRecordedInvestment1_259507b2-39d1-4c6d-8217-a0e41bd5ec56_terseLabel_en-US" xlink:label="lab_us-gaap_FinancingReceivableModificationsSubsequentDefaultRecordedInvestment1" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Payment Default(3)</link:label>
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    <link:label id="lab_slm_SeasoningBasedOnMonthlyScheduledPaymentsDueFromNotYetInRepaymentMember_db897511-49f2-41f7-b24d-7f60288df504_terseLabel_en-US" xlink:label="lab_slm_SeasoningBasedOnMonthlyScheduledPaymentsDueFromNotYetInRepaymentMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Not yet in repayment</link:label>
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    <link:label id="lab_slm_SeasoningBasedOnMonthlyScheduledPaymentsDueFromNotYetInRepaymentMember_documentation_en-US" xlink:label="lab_slm_SeasoningBasedOnMonthlyScheduledPaymentsDueFromNotYetInRepaymentMember" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Seasoning Based On Monthly Scheduled Payments Due From Not Yet In Repayment [Member]</link:label>
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    <link:label id="lab_us-gaap_CashAndCashEquivalentsAtCarryingValue_7a3f0651-3db2-42a6-b672-0a9adad17b42_terseLabel_en-US" xlink:label="lab_us-gaap_CashAndCashEquivalentsAtCarryingValue" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Cash and cash equivalents</link:label>
    <link:label id="lab_us-gaap_CashAndCashEquivalentsAtCarryingValue_ae7fc32b-34d5-4824-b6ca-1aa18a90a10b_verboseLabel_en-US" xlink:label="lab_us-gaap_CashAndCashEquivalentsAtCarryingValue" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Cash and cash equivalents</link:label>
    <link:label id="lab_us-gaap_CashAndCashEquivalentsAtCarryingValue_label_en-US" xlink:label="lab_us-gaap_CashAndCashEquivalentsAtCarryingValue" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Cash and Cash Equivalents, at Carrying Value</link:label>
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    <link:label id="lab_us-gaap_DesignatedAsHedgingInstrumentMember_cfddcfd3-591f-4c8f-a942-73901c649af7_terseLabel_en-US" xlink:label="lab_us-gaap_DesignatedAsHedgingInstrumentMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Designated as Hedging Instrument</link:label>
    <link:label id="lab_us-gaap_DesignatedAsHedgingInstrumentMember_label_en-US" xlink:label="lab_us-gaap_DesignatedAsHedgingInstrumentMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Designated as Hedging Instrument [Member]</link:label>
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    <link:label id="lab_slm_Netincreasedecreaseinbrokeredcertificatesofdeposit_1091e992-ef31-4ccc-8db9-e9128c852f4b_terseLabel_en-US" xlink:label="lab_slm_Netincreasedecreaseinbrokeredcertificatesofdeposit" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Net increase (decrease) in certificates of deposit</link:label>
    <link:label id="lab_slm_Netincreasedecreaseinbrokeredcertificatesofdeposit_label_en-US" xlink:label="lab_slm_Netincreasedecreaseinbrokeredcertificatesofdeposit" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Net increase (decrease) in brokered certificates of deposit</link:label>
    <link:label id="lab_slm_Netincreasedecreaseinbrokeredcertificatesofdeposit_documentation_en-US" xlink:label="lab_slm_Netincreasedecreaseinbrokeredcertificatesofdeposit" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Net increase (decrease) in brokered certificates of deposit</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_slm_Netincreasedecreaseinbrokeredcertificatesofdeposit" xlink:href="slm-20230331.xsd#slm_Netincreasedecreaseinbrokeredcertificatesofdeposit"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_slm_Netincreasedecreaseinbrokeredcertificatesofdeposit" xlink:to="lab_slm_Netincreasedecreaseinbrokeredcertificatesofdeposit" xlink:type="arc" order="1"/>
    <link:label id="lab_slm_Maturity2053Member_6184900c-9dcc-4efc-a7f2-7019ada7ac37_terseLabel_en-US" xlink:label="lab_slm_Maturity2053Member" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">2053</link:label>
    <link:label id="lab_slm_Maturity2053Member_label_en-US" xlink:label="lab_slm_Maturity2053Member" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Maturity 2053 [Member]</link:label>
    <link:label id="lab_slm_Maturity2053Member_documentation_en-US" xlink:label="lab_slm_Maturity2053Member" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Maturity 2053</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_slm_Maturity2053Member" xlink:href="slm-20230331.xsd#slm_Maturity2053Member"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_slm_Maturity2053Member" xlink:to="lab_slm_Maturity2053Member" xlink:type="arc" order="1"/>
    <link:label id="lab_slm_Maturity2050Member_cebd5af6-fb0e-42e0-9a28-ff62e1d47136_terseLabel_en-US" xlink:label="lab_slm_Maturity2050Member" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">2050</link:label>
    <link:label id="lab_slm_Maturity2050Member_label_en-US" xlink:label="lab_slm_Maturity2050Member" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Maturity 2050 [Member]</link:label>
    <link:label id="lab_slm_Maturity2050Member_documentation_en-US" xlink:label="lab_slm_Maturity2050Member" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Maturity 2050</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_slm_Maturity2050Member" xlink:href="slm-20230331.xsd#slm_Maturity2050Member"/>
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    <link:label id="lab_us-gaap_LoanRestructuringModificationDomain_2b6db2ac-5a0f-45c4-8f76-49a2fe9b001f_terseLabel_en-US" xlink:label="lab_us-gaap_LoanRestructuringModificationDomain" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Loan Restructuring Modification [Domain]</link:label>
    <link:label id="lab_us-gaap_LoanRestructuringModificationDomain_label_en-US" xlink:label="lab_us-gaap_LoanRestructuringModificationDomain" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Loan Restructuring Modification [Domain]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LoanRestructuringModificationDomain" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_LoanRestructuringModificationDomain"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_LoanRestructuringModificationDomain" xlink:to="lab_us-gaap_LoanRestructuringModificationDomain" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_FairValueMeasurementFrequencyDomain_d88fc287-be84-46af-998f-a37dcbd18bbd_terseLabel_en-US" xlink:label="lab_us-gaap_FairValueMeasurementFrequencyDomain" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Measurement Frequency [Domain]</link:label>
    <link:label id="lab_us-gaap_FairValueMeasurementFrequencyDomain_label_en-US" xlink:label="lab_us-gaap_FairValueMeasurementFrequencyDomain" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Measurement Frequency [Domain]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueMeasurementFrequencyDomain" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_FairValueMeasurementFrequencyDomain"/>
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    <link:label id="lab_us-gaap_AffordableHousingTaxCreditsAndOtherTaxBenefitsAmount_0a5b6767-64dd-422e-ae5d-908a28c73167_terseLabel_en-US" xlink:label="lab_us-gaap_AffordableHousingTaxCreditsAndOtherTaxBenefitsAmount" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Low income housing tax credit investments, tax credits and benefits (less than)</link:label>
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    <link:label id="lab_us-gaap_StockholdersEquityNoteDisclosureTextBlock_5b43f92b-ce93-4ab0-9c97-be344fb404c6_terseLabel_en-US" xlink:label="lab_us-gaap_StockholdersEquityNoteDisclosureTextBlock" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Stockholders' Equity</link:label>
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    <link:label id="lab_slm_LoansAbstract_658f61dc-8f2f-46dc-b396-49ad0e43efa2_terseLabel_en-US" xlink:label="lab_slm_LoansAbstract" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Loans</link:label>
    <link:label id="lab_slm_LoansAbstract_label_en-US" xlink:label="lab_slm_LoansAbstract" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Loans [Abstract]</link:label>
    <link:label id="lab_slm_LoansAbstract_documentation_en-US" xlink:label="lab_slm_LoansAbstract" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Loans.</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_slm_LoansAbstract" xlink:href="slm-20230331.xsd#slm_LoansAbstract"/>
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    <link:label id="lab_us-gaap_LineOfCreditFacilityTable_3749bd3b-b77f-4b74-b051-701f45616474_terseLabel_en-US" xlink:label="lab_us-gaap_LineOfCreditFacilityTable" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Line of Credit Facility [Table]</link:label>
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    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LineOfCreditFacilityTable" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_LineOfCreditFacilityTable"/>
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    <link:label id="lab_us-gaap_PaymentsToAcquireAvailableForSaleSecuritiesDebt_ac53a3ff-4ef6-4e65-ae74-3c9ae524dd1c_negatedLabel_en-US" xlink:label="lab_us-gaap_PaymentsToAcquireAvailableForSaleSecuritiesDebt" xlink:role="http://www.xbrl.org/2009/role/negatedLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Purchases of available-for-sale securities</link:label>
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    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsToAcquireAvailableForSaleSecuritiesDebt" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_PaymentsToAcquireAvailableForSaleSecuritiesDebt"/>
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    <link:label id="lab_us-gaap_ShortTermBorrowings_35f43dee-9a14-4791-8d1b-7928925544c0_verboseLabel_en-US" xlink:label="lab_us-gaap_ShortTermBorrowings" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Short-Term</link:label>
    <link:label id="lab_us-gaap_ShortTermBorrowings_label_en-US" xlink:label="lab_us-gaap_ShortTermBorrowings" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Short-Term Debt</link:label>
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    <link:label id="lab_us-gaap_LoansReceivableFairValueDisclosure_5c3b57ef-847d-40c0-8ea1-d28a63be2409_terseLabel_en-US" xlink:label="lab_us-gaap_LoansReceivableFairValueDisclosure" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Loans held for investment, net</link:label>
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    <link:label id="lab_us-gaap_ScheduleOfVariableInterestEntitiesTextBlock_4646230d-3320-4e06-a658-a07dcccd94c6_terseLabel_en-US" xlink:label="lab_us-gaap_ScheduleOfVariableInterestEntitiesTextBlock" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Schedule of Variable Interest Entities</link:label>
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    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SecuritiesFinancingTransactionLineItems" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_SecuritiesFinancingTransactionLineItems"/>
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    <link:label id="lab_slm_LoansGrossOriginatedThreeYearsBeforeLatestFiscalYear_03fad3bf-d2a2-4bd2-bb81-5ce60f8e613d_terseLabel_en-US" xlink:label="lab_slm_LoansGrossOriginatedThreeYearsBeforeLatestFiscalYear" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Total Private Education Loans, gross, Year 4</link:label>
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    <link:label id="lab_slm_LoansGrossOriginatedThreeYearsBeforeLatestFiscalYear_documentation_en-US" xlink:label="lab_slm_LoansGrossOriginatedThreeYearsBeforeLatestFiscalYear" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Loans Gross, Originated Three Years Before Latest Fiscal Year</link:label>
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    <link:label id="lab_slm_AvailableForSaleSecuritiesUnrealizedLossPositionAbstract_2882f686-dd76-4306-b022-94c2d0a845aa_terseLabel_en-US" xlink:label="lab_slm_AvailableForSaleSecuritiesUnrealizedLossPositionAbstract" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Total</link:label>
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    <link:label id="lab_us-gaap_IncreaseDecreaseInInterestPayableNet_486558cb-f9a6-4cdd-8848-1f5f5d247bf2_terseLabel_en-US" xlink:label="lab_us-gaap_IncreaseDecreaseInInterestPayableNet" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Increase in accrued interest payable</link:label>
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    <link:label id="lab_slm_PercentageOfLoansInRepaymentOriginatedFourYearsBeforeLatestFiscalYear_43c7905a-fc67-447b-9313-5f5ef82f6a75_terseLabel_en-US" xlink:label="lab_slm_PercentageOfLoansInRepaymentOriginatedFourYearsBeforeLatestFiscalYear" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Percentage of Private Education Loans in repayment, Year 5</link:label>
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    <link:label id="lab_us-gaap_ScheduleOfDebtTableTextBlock_2af89ecf-9771-409f-a2aa-676dc3d1609a_terseLabel_en-US" xlink:label="lab_us-gaap_ScheduleOfDebtTableTextBlock" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Schedule of Debt</link:label>
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    <link:label id="lab_us-gaap_DebtInstrumentTable_48f11033-f3c4-4304-ac5b-56470b6ccb4b_terseLabel_en-US" xlink:label="lab_us-gaap_DebtInstrumentTable" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Schedule of Long-term Debt Instruments [Table]</link:label>
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    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_DebtInstrumentTable" xlink:to="lab_us-gaap_DebtInstrumentTable" xlink:type="arc" order="1"/>
    <link:label id="lab_slm_SchoolFicoMember_31e3d321-b7e6-4c7b-95e9-cc3c4ccb3941_terseLabel_en-US" xlink:label="lab_slm_SchoolFicoMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">FICO at Origination</link:label>
    <link:label id="lab_slm_SchoolFicoMember_label_en-US" xlink:label="lab_slm_SchoolFicoMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">School Fico [Member]</link:label>
    <link:label id="lab_slm_SchoolFicoMember_documentation_en-US" xlink:label="lab_slm_SchoolFicoMember" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">School type fico credit quality indicators that are developed and used internally by the company.</link:label>
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    <link:label id="lab_us-gaap_FairValueInputsLevel3Member_862ed1f1-66a6-4da1-94b5-b888674776e0_terseLabel_en-US" xlink:label="lab_us-gaap_FairValueInputsLevel3Member" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Level&#160;3&#160;</link:label>
    <link:label id="lab_us-gaap_FairValueInputsLevel3Member_label_en-US" xlink:label="lab_us-gaap_FairValueInputsLevel3Member" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Fair Value, Inputs, Level 3 [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueInputsLevel3Member" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_FairValueInputsLevel3Member"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_FairValueInputsLevel3Member" xlink:to="lab_us-gaap_FairValueInputsLevel3Member" xlink:type="arc" order="1"/>
    <link:label id="lab_slm_AdoptionOfNewAccountingPronouncementsPercentPhasedInDuringYear_fe05722e-107a-43c0-b47e-c74d9bd8a1d3_terseLabel_en-US" xlink:label="lab_slm_AdoptionOfNewAccountingPronouncementsPercentPhasedInDuringYear" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Percentage amount phased in during year</link:label>
    <link:label id="lab_slm_AdoptionOfNewAccountingPronouncementsPercentPhasedInDuringYear_label_en-US" xlink:label="lab_slm_AdoptionOfNewAccountingPronouncementsPercentPhasedInDuringYear" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Adoption Of New Accounting Pronouncements, Percent Phased In During Year</link:label>
    <link:label id="lab_slm_AdoptionOfNewAccountingPronouncementsPercentPhasedInDuringYear_documentation_en-US" xlink:label="lab_slm_AdoptionOfNewAccountingPronouncementsPercentPhasedInDuringYear" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Adoption Of New Accounting Pronouncements, Percent Phased In During Year</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_slm_AdoptionOfNewAccountingPronouncementsPercentPhasedInDuringYear" xlink:href="slm-20230331.xsd#slm_AdoptionOfNewAccountingPronouncementsPercentPhasedInDuringYear"/>
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    <link:label id="lab_slm_StableInterestbearingDepositsTotal_abe56b76-3a2e-4821-a60b-371bd551cb12_terseLabel_en-US" xlink:label="lab_slm_StableInterestbearingDepositsTotal" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Stable interest-bearing deposits, total</link:label>
    <link:label id="lab_slm_StableInterestbearingDepositsTotal_label_en-US" xlink:label="lab_slm_StableInterestbearingDepositsTotal" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Stable Interest-bearing Deposits, Total</link:label>
    <link:label id="lab_slm_StableInterestbearingDepositsTotal_documentation_en-US" xlink:label="lab_slm_StableInterestbearingDepositsTotal" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Stable Interest-bearing Deposits, Total</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_slm_StableInterestbearingDepositsTotal" xlink:href="slm-20230331.xsd#slm_StableInterestbearingDepositsTotal"/>
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    <link:label id="lab_us-gaap_WeightedAverageRateDomesticDepositSavings_bea9eea9-7be6-4a00-8f86-db415f37369e_terseLabel_en-US" xlink:label="lab_us-gaap_WeightedAverageRateDomesticDepositSavings" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Savings</link:label>
    <link:label id="lab_us-gaap_WeightedAverageRateDomesticDepositSavings_label_en-US" xlink:label="lab_us-gaap_WeightedAverageRateDomesticDepositSavings" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Weighted Average Rate Domestic Deposit, Savings</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_WeightedAverageRateDomesticDepositSavings" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_WeightedAverageRateDomesticDepositSavings"/>
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    <link:label id="lab_slm_SeasoningBasedOnMonthlyScheduledPaymentsDueFromThirteenToTwentyFourPaymentsInPercent_47dcbb19-fb0e-44fb-a63f-872786ee4ba0_terseLabel_en-US" xlink:label="lab_slm_SeasoningBasedOnMonthlyScheduledPaymentsDueFromThirteenToTwentyFourPaymentsInPercent" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Seasoning based on monthly scheduled payments due from 13 - 24 payments</link:label>
    <link:label id="lab_slm_SeasoningBasedOnMonthlyScheduledPaymentsDueFromThirteenToTwentyFourPaymentsInPercent_label_en-US" xlink:label="lab_slm_SeasoningBasedOnMonthlyScheduledPaymentsDueFromThirteenToTwentyFourPaymentsInPercent" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Seasoning Based On Monthly Scheduled Payments Due From Thirteen To Twenty Four Payments In Percent</link:label>
    <link:label id="lab_slm_SeasoningBasedOnMonthlyScheduledPaymentsDueFromThirteenToTwentyFourPaymentsInPercent_documentation_en-US" xlink:label="lab_slm_SeasoningBasedOnMonthlyScheduledPaymentsDueFromThirteenToTwentyFourPaymentsInPercent" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Seasoning based on monthly scheduled payments due from thirteen to twenty four payments in percent.</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_slm_SeasoningBasedOnMonthlyScheduledPaymentsDueFromThirteenToTwentyFourPaymentsInPercent" xlink:href="slm-20230331.xsd#slm_SeasoningBasedOnMonthlyScheduledPaymentsDueFromThirteenToTwentyFourPaymentsInPercent"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_slm_SeasoningBasedOnMonthlyScheduledPaymentsDueFromThirteenToTwentyFourPaymentsInPercent" xlink:to="lab_slm_SeasoningBasedOnMonthlyScheduledPaymentsDueFromThirteenToTwentyFourPaymentsInPercent" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_TimeDepositMaturitiesNextRollingTwelveMonths_82ff6c15-9626-4f54-8f72-d44e4d3671bd_terseLabel_en-US" xlink:label="lab_us-gaap_TimeDepositMaturitiesNextRollingTwelveMonths" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">One year or less</link:label>
    <link:label id="lab_us-gaap_TimeDepositMaturitiesNextRollingTwelveMonths_label_en-US" xlink:label="lab_us-gaap_TimeDepositMaturitiesNextRollingTwelveMonths" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Time Deposit Maturities, Next Rolling 12 Months</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_TimeDepositMaturitiesNextRollingTwelveMonths" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_TimeDepositMaturitiesNextRollingTwelveMonths"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_TimeDepositMaturitiesNextRollingTwelveMonths" xlink:to="lab_us-gaap_TimeDepositMaturitiesNextRollingTwelveMonths" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_InterestIncomeExpenseNet_65f8abb0-371a-4892-a4a8-3fc6f984fd06_totalLabel_en-US" xlink:label="lab_us-gaap_InterestIncomeExpenseNet" xlink:role="http://www.xbrl.org/2003/role/totalLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Net interest income</link:label>
    <link:label id="lab_us-gaap_InterestIncomeExpenseNet_label_en-US" xlink:label="lab_us-gaap_InterestIncomeExpenseNet" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Interest Income (Expense), Net</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestIncomeExpenseNet" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_InterestIncomeExpenseNet"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_InterestIncomeExpenseNet" xlink:to="lab_us-gaap_InterestIncomeExpenseNet" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_NoninterestIncomeAbstract_d6e6de3d-0d42-4944-84f1-dc69988ad848_terseLabel_en-US" xlink:label="lab_us-gaap_NoninterestIncomeAbstract" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Non-interest income:</link:label>
    <link:label id="lab_us-gaap_NoninterestIncomeAbstract_label_en-US" xlink:label="lab_us-gaap_NoninterestIncomeAbstract" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Noninterest Income [Abstract]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NoninterestIncomeAbstract" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_NoninterestIncomeAbstract"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_NoninterestIncomeAbstract" xlink:to="lab_us-gaap_NoninterestIncomeAbstract" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_ChangeInUnrealizedGainLossOnHedgedItemInFairValueHedge1_a823ec10-96c3-4cc5-a4ed-54ad4398a7f6_terseLabel_en-US" xlink:label="lab_us-gaap_ChangeInUnrealizedGainLossOnHedgedItemInFairValueHedge1" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Hedged items recorded in interest expense</link:label>
    <link:label id="lab_us-gaap_ChangeInUnrealizedGainLossOnHedgedItemInFairValueHedge1_label_en-US" xlink:label="lab_us-gaap_ChangeInUnrealizedGainLossOnHedgedItemInFairValueHedge1" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Change in Unrealized Gain (Loss) on Hedged Item in Fair Value Hedge</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ChangeInUnrealizedGainLossOnHedgedItemInFairValueHedge1" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ChangeInUnrealizedGainLossOnHedgedItemInFairValueHedge1"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_ChangeInUnrealizedGainLossOnHedgedItemInFairValueHedge1" xlink:to="lab_us-gaap_ChangeInUnrealizedGainLossOnHedgedItemInFairValueHedge1" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_InterestReceivable_9fde14f4-64da-4232-9ec0-316b6fec8817_terseLabel_en-US" xlink:label="lab_us-gaap_InterestReceivable" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Accrued interest receivable</link:label>
    <link:label id="lab_us-gaap_InterestReceivable_label_en-US" xlink:label="lab_us-gaap_InterestReceivable" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Interest Receivable</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestReceivable" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_InterestReceivable"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_InterestReceivable" xlink:to="lab_us-gaap_InterestReceivable" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_DepositLiabilitiesDisclosuresTextBlock_e7431472-38bd-4174-8441-af1de184e8e7_terseLabel_en-US" xlink:label="lab_us-gaap_DepositLiabilitiesDisclosuresTextBlock" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Deposits</link:label>
    <link:label id="lab_us-gaap_DepositLiabilitiesDisclosuresTextBlock_label_en-US" xlink:label="lab_us-gaap_DepositLiabilitiesDisclosuresTextBlock" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Deposit Liabilities Disclosures [Text Block]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DepositLiabilitiesDisclosuresTextBlock" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_DepositLiabilitiesDisclosuresTextBlock"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_DepositLiabilitiesDisclosuresTextBlock" xlink:to="lab_us-gaap_DepositLiabilitiesDisclosuresTextBlock" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_IncrementalCommonSharesAttributableToShareBasedPaymentArrangements_f76e5b28-81f1-44d6-a8b6-98685a5b331d_terseLabel_en-US" xlink:label="lab_us-gaap_IncrementalCommonSharesAttributableToShareBasedPaymentArrangements" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Dilutive effect of stock options, restricted stock, restricted stock units and Employee Stock Purchase Plan (ESPP) (in shares)</link:label>
    <link:label id="lab_us-gaap_IncrementalCommonSharesAttributableToShareBasedPaymentArrangements_label_en-US" xlink:label="lab_us-gaap_IncrementalCommonSharesAttributableToShareBasedPaymentArrangements" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Incremental Common Shares Attributable to Dilutive Effect of Share-Based Payment Arrangements</link:label>
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    <link:label id="lab_us-gaap_FairValueInputsLevel2Member_499ba63f-5948-45f0-b447-872287075c40_terseLabel_en-US" xlink:label="lab_us-gaap_FairValueInputsLevel2Member" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Level&#160;2&#160;</link:label>
    <link:label id="lab_us-gaap_FairValueInputsLevel2Member_label_en-US" xlink:label="lab_us-gaap_FairValueInputsLevel2Member" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Fair Value, Inputs, Level 2 [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueInputsLevel2Member" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_FairValueInputsLevel2Member"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_FairValueInputsLevel2Member" xlink:to="lab_us-gaap_FairValueInputsLevel2Member" xlink:type="arc" order="1"/>
    <link:label id="lab_slm_DelinquenciesAsPercentageOfLoansInRepaymentOriginatedFourYearsBeforeCurrentFiscalYear_7aa522fb-d3cf-406b-89a3-e76a92a5aadd_terseLabel_en-US" xlink:label="lab_slm_DelinquenciesAsPercentageOfLoansInRepaymentOriginatedFourYearsBeforeCurrentFiscalYear" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Delinquent Private Education Loans in repayment as a percentage of Private Education Loans in repayment, Year 5</link:label>
    <link:label id="lab_slm_DelinquenciesAsPercentageOfLoansInRepaymentOriginatedFourYearsBeforeCurrentFiscalYear_label_en-US" xlink:label="lab_slm_DelinquenciesAsPercentageOfLoansInRepaymentOriginatedFourYearsBeforeCurrentFiscalYear" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Delinquencies As Percentage Of Loans In Repayment, Originated Four Years Before Current Fiscal Year</link:label>
    <link:label id="lab_slm_DelinquenciesAsPercentageOfLoansInRepaymentOriginatedFourYearsBeforeCurrentFiscalYear_documentation_en-US" xlink:label="lab_slm_DelinquenciesAsPercentageOfLoansInRepaymentOriginatedFourYearsBeforeCurrentFiscalYear" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Delinquencies As Percentage Of Loans In Repayment, Originated Four Years Before Current Fiscal Year</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_slm_DelinquenciesAsPercentageOfLoansInRepaymentOriginatedFourYearsBeforeCurrentFiscalYear" xlink:href="slm-20230331.xsd#slm_DelinquenciesAsPercentageOfLoansInRepaymentOriginatedFourYearsBeforeCurrentFiscalYear"/>
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    <link:label id="lab_slm_ChangeInOtherComprehensiveIncomeLossForUnrealizedGainsLossesOnDerivativesBeforeIncomeTaxExpenseBenefit_e2163e98-aa4e-4277-9522-d0f860103906_totalLabel_en-US" xlink:label="lab_slm_ChangeInOtherComprehensiveIncomeLossForUnrealizedGainsLossesOnDerivativesBeforeIncomeTaxExpenseBenefit" xlink:role="http://www.xbrl.org/2003/role/totalLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Total change in other comprehensive income (loss) for unrealized gains (losses) on derivatives, before income tax (expense) benefit</link:label>
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    <link:label id="lab_slm_FICOscore700749Member_6fc96e1b-48af-4905-b60a-4a955c98c6de_terseLabel_en-US" xlink:label="lab_slm_FICOscore700749Member" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">700-749</link:label>
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    <link:label id="lab_slm_OffBalanceSheetCreditLossLiabilityTransferFromUnfundedCommitments_e1a5536d-c5f4-4c43-8dcd-9f6ec1a79241_terseLabel_en-US" xlink:label="lab_slm_OffBalanceSheetCreditLossLiabilityTransferFromUnfundedCommitments" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Transfer from unfunded commitment liability</link:label>
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    <link:label id="lab_slm_TierOneCommonEquityCapitalRequiredtobeWellCapitalizedtoRiskWeightedAssets_597d5bc1-dc25-4717-8193-a6f0bb935396_terseLabel_en-US" xlink:label="lab_slm_TierOneCommonEquityCapitalRequiredtobeWellCapitalizedtoRiskWeightedAssets" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Common Equity Tier 1 Capital (to Risk-Weighted Assets)</link:label>
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    <link:label id="lab_exch_XCME_e1864c2e-9702-418c-ab2c-423a14cc2cda_terseLabel_en-US" xlink:label="lab_exch_XCME" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">CME</link:label>
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    <link:label id="lab_slm_Maturity2038Member_99f3c583-179c-498d-8533-c0fa0750c8ca_terseLabel_en-US" xlink:label="lab_slm_Maturity2038Member" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">2038</link:label>
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    <link:label id="lab_slm_MoneyMarketandSavingsAccountsMember_e588f981-75ad-4fdc-b7ff-07eec3ea2dcd_terseLabel_en-US" xlink:label="lab_slm_MoneyMarketandSavingsAccountsMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Money-market and savings accounts</link:label>
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    <link:label id="lab_us-gaap_LeverageRatiosAbstract_be579cdb-4e22-4301-b29a-c7f1180f7afa_verboseLabel_en-US" xlink:label="lab_us-gaap_LeverageRatiosAbstract" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">U.S. Basel III Regulatory Requirements, Ratio</link:label>
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    <link:label id="lab_us-gaap_FinancialInstrumentsFinancialAssetsBalanceSheetGroupingsAbstract_63499e8b-bd6a-4745-aa1b-fa67f6d01ef0_terseLabel_en-US" xlink:label="lab_us-gaap_FinancialInstrumentsFinancialAssetsBalanceSheetGroupingsAbstract" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Earning assets:</link:label>
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    <link:label id="lab_us-gaap_CapitalRequiredToBeWellCapitalized_0d2fdc6e-d43d-43b5-8eed-db8d589c8513_terseLabel_en-US" xlink:label="lab_us-gaap_CapitalRequiredToBeWellCapitalized" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Total Capital (to Risk-Weighted Assets)</link:label>
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    <link:label id="lab_slm_LoansSecuritizedOrAssetBackedFinancingArrangementOwnershipInterestPercentage_bc2b3f28-1025-4a24-bd42-dc3d87fc4aeb_terseLabel_en-US" xlink:label="lab_slm_LoansSecuritizedOrAssetBackedFinancingArrangementOwnershipInterestPercentage" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Ownership interest percentage on asset-backed financing</link:label>
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    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_FairValueDisclosuresAbstract" xlink:to="lab_us-gaap_FairValueDisclosuresAbstract" xlink:type="arc" order="1"/>
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    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeInstrumentsAndHedgingActivitiesDisclosureAbstract" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_DerivativeInstrumentsAndHedgingActivitiesDisclosureAbstract"/>
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    <link:label id="lab_slm_PrivateEducationLoansMember_9dee4987-a68d-4ed2-a6da-ff4c31d9fa9d_terseLabel_en-US" xlink:label="lab_slm_PrivateEducationLoansMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Private Education Loans</link:label>
    <link:label id="lab_slm_PrivateEducationLoansMember_c202200b-8287-4327-bec8-c1bb4fccc425_verboseLabel_en-US" xlink:label="lab_slm_PrivateEducationLoansMember" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Private Education Loans</link:label>
    <link:label id="lab_slm_PrivateEducationLoansMember_label_en-US" xlink:label="lab_slm_PrivateEducationLoansMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Private Education Loans [Member]</link:label>
    <link:label id="lab_slm_PrivateEducationLoansMember_documentation_en-US" xlink:label="lab_slm_PrivateEducationLoansMember" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Private education loans.</link:label>
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    <link:label id="lab_us-gaap_ProceedsFromSaleAndMaturityOfAvailableForSaleSecurities_323a55c6-75c4-421e-8600-a2bae7bd4b41_terseLabel_en-US" xlink:label="lab_us-gaap_ProceedsFromSaleAndMaturityOfAvailableForSaleSecurities" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Proceeds from sales and maturities of available-for-sale securities</link:label>
    <link:label id="lab_us-gaap_ProceedsFromSaleAndMaturityOfAvailableForSaleSecurities_label_en-US" xlink:label="lab_us-gaap_ProceedsFromSaleAndMaturityOfAvailableForSaleSecurities" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Proceeds from Sale and Maturity of Debt Securities, Available-for-Sale</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProceedsFromSaleAndMaturityOfAvailableForSaleSecurities" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ProceedsFromSaleAndMaturityOfAvailableForSaleSecurities"/>
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    <link:label id="lab_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsAbstract_68905f41-c6b2-4c07-9298-942619cf294a_terseLabel_en-US" xlink:label="lab_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsAbstract" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Reconciliation of the Consolidated Statements of Cash Flows to the Consolidated Balance Sheets:</link:label>
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    <link:label id="lab_us-gaap_EquityAbstract_0a7a2ba2-c2ed-4f35-b248-51f3636fa3a0_terseLabel_en-US" xlink:label="lab_us-gaap_EquityAbstract" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Equity [Abstract]</link:label>
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    <link:label id="lab_slm_FinancingReceivableBeforeAllowanceForCreditLossAverageBalance_ca5d2df9-a902-471a-94f3-8387eac5c5b6_terseLabel_en-US" xlink:label="lab_slm_FinancingReceivableBeforeAllowanceForCreditLossAverageBalance" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Average Balance</link:label>
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    <link:label id="lab_dei_EntityTaxIdentificationNumber_5d53ab4d-84db-4e24-8360-0cae7fef5d8b_terseLabel_en-US" xlink:label="lab_dei_EntityTaxIdentificationNumber" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Entity Tax Identification Number</link:label>
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    <link:label id="lab_us-gaap_DerivativesFairValueLineItems_67a81c82-11c7-46d3-8c97-d71bd63597f7_terseLabel_en-US" xlink:label="lab_us-gaap_DerivativesFairValueLineItems" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Derivatives, Fair Value [Line Items]</link:label>
    <link:label id="lab_us-gaap_DerivativesFairValueLineItems_label_en-US" xlink:label="lab_us-gaap_DerivativesFairValueLineItems" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Derivatives, Fair Value [Line Items]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativesFairValueLineItems" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_DerivativesFairValueLineItems"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_DerivativesFairValueLineItems" xlink:to="lab_us-gaap_DerivativesFairValueLineItems" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_SecuritiesLoanedFairValueOfCollateral_9f4b6b5f-8a9e-4a3b-893f-b5bab61e3527_terseLabel_en-US" xlink:label="lab_us-gaap_SecuritiesLoanedFairValueOfCollateral" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Loans pledged as collateral</link:label>
    <link:label id="lab_us-gaap_SecuritiesLoanedFairValueOfCollateral_label_en-US" xlink:label="lab_us-gaap_SecuritiesLoanedFairValueOfCollateral" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Securities Loaned, Fair Value of Collateral</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SecuritiesLoanedFairValueOfCollateral" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_SecuritiesLoanedFairValueOfCollateral"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_SecuritiesLoanedFairValueOfCollateral" xlink:to="lab_us-gaap_SecuritiesLoanedFairValueOfCollateral" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_TradingActivityByTypeAxis_23733910-aa7e-4a73-969c-8ce8d6674274_terseLabel_en-US" xlink:label="lab_us-gaap_TradingActivityByTypeAxis" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Trading Activity [Axis]</link:label>
    <link:label id="lab_us-gaap_TradingActivityByTypeAxis_label_en-US" xlink:label="lab_us-gaap_TradingActivityByTypeAxis" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Trading Activity [Axis]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_TradingActivityByTypeAxis" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_TradingActivityByTypeAxis"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_TradingActivityByTypeAxis" xlink:to="lab_us-gaap_TradingActivityByTypeAxis" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_FinancingReceivableAllowanceForCreditLossesWriteOffs_394bdb96-e473-443d-a05a-56633d9f0736_terseLabel_en-US" xlink:label="lab_us-gaap_FinancingReceivableAllowanceForCreditLossesWriteOffs" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Charge-off</link:label>
    <link:label id="lab_us-gaap_FinancingReceivableAllowanceForCreditLossesWriteOffs_label_en-US" xlink:label="lab_us-gaap_FinancingReceivableAllowanceForCreditLossesWriteOffs" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Financing Receivable, Allowance for Credit Loss, Writeoff</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinancingReceivableAllowanceForCreditLossesWriteOffs" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_FinancingReceivableAllowanceForCreditLossesWriteOffs"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_FinancingReceivableAllowanceForCreditLossesWriteOffs" xlink:to="lab_us-gaap_FinancingReceivableAllowanceForCreditLossesWriteOffs" xlink:type="arc" order="1"/>
    <link:label id="lab_srt_ConsolidatedEntitiesDomain_bad53352-d4e4-4360-a92c-bd7bcbea2a30_terseLabel_en-US" xlink:label="lab_srt_ConsolidatedEntitiesDomain" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Consolidated Entities [Domain]</link:label>
    <link:label id="lab_srt_ConsolidatedEntitiesDomain_label_en-US" xlink:label="lab_srt_ConsolidatedEntitiesDomain" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Consolidated Entities [Domain]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_srt_ConsolidatedEntitiesDomain" xlink:href="https://xbrl.fasb.org/srt/2022/elts/srt-2022.xsd#srt_ConsolidatedEntitiesDomain"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_srt_ConsolidatedEntitiesDomain" xlink:to="lab_srt_ConsolidatedEntitiesDomain" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_SharesPaidForTaxWithholdingForShareBasedCompensation_3f2341aa-6e83-4c97-a517-7d1cc60dda01_negatedTerseLabel_en-US" xlink:label="lab_us-gaap_SharesPaidForTaxWithholdingForShareBasedCompensation" xlink:role="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Shares repurchased related to employee stock-based compensation plans (in shares)</link:label>
    <link:label id="lab_us-gaap_SharesPaidForTaxWithholdingForShareBasedCompensation_34293202-78c5-44ab-9155-0f243e6ca625_terseLabel_en-US" xlink:label="lab_us-gaap_SharesPaidForTaxWithholdingForShareBasedCompensation" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Shares repurchased related to employee stock-based compensation plans (in shares)</link:label>
    <link:label id="lab_us-gaap_SharesPaidForTaxWithholdingForShareBasedCompensation_label_en-US" xlink:label="lab_us-gaap_SharesPaidForTaxWithholdingForShareBasedCompensation" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Share-Based Payment Arrangement, Shares Withheld for Tax Withholding Obligation</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SharesPaidForTaxWithholdingForShareBasedCompensation" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_SharesPaidForTaxWithholdingForShareBasedCompensation"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_SharesPaidForTaxWithholdingForShareBasedCompensation" xlink:to="lab_us-gaap_SharesPaidForTaxWithholdingForShareBasedCompensation" xlink:type="arc" order="1"/>
    <link:label id="lab_slm_AmortizationOfABCPUpfrontLoanFees_a0faaef8-de25-4982-9551-99276871dfab_terseLabel_en-US" xlink:label="lab_slm_AmortizationOfABCPUpfrontLoanFees" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Amortization of Secured Borrowing Facility upfront fee</link:label>
    <link:label id="lab_slm_AmortizationOfABCPUpfrontLoanFees_label_en-US" xlink:label="lab_slm_AmortizationOfABCPUpfrontLoanFees" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Amortization of ABCP Upfront Loan Fees</link:label>
    <link:label id="lab_slm_AmortizationOfABCPUpfrontLoanFees_documentation_en-US" xlink:label="lab_slm_AmortizationOfABCPUpfrontLoanFees" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Amortization of ABCP Upfront Loan Fees</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_slm_AmortizationOfABCPUpfrontLoanFees" xlink:href="slm-20230331.xsd#slm_AmortizationOfABCPUpfrontLoanFees"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_slm_AmortizationOfABCPUpfrontLoanFees" xlink:to="lab_slm_AmortizationOfABCPUpfrontLoanFees" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect_7849dc14-a774-4fe5-8db7-42075bb7079f_totalLabel_en-US" xlink:label="lab_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect" xlink:role="http://www.xbrl.org/2003/role/totalLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Net increase (decrease) in cash, cash equivalents and restricted cash</link:label>
    <link:label id="lab_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect_label_en-US" xlink:label="lab_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Cash, Cash Equivalents, Restricted Cash, and Restricted Cash Equivalents, Period Increase (Decrease), Including Exchange Rate Effect</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect" xlink:to="lab_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect" xlink:type="arc" order="1"/>
    <link:label id="lab_dei_EntityCentralIndexKey_ee4f519a-c0e4-4122-80ed-d2685c5a2365_terseLabel_en-US" xlink:label="lab_dei_EntityCentralIndexKey" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Entity Central Index Key</link:label>
    <link:label id="lab_dei_EntityCentralIndexKey_label_en-US" xlink:label="lab_dei_EntityCentralIndexKey" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Entity Central Index Key</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityCentralIndexKey" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_EntityCentralIndexKey"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_dei_EntityCentralIndexKey" xlink:to="lab_dei_EntityCentralIndexKey" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_FiniteLivedIntangibleAssetsByMajorClassAxis_a8ad2b45-8a89-443a-a3c7-6681ffd2383b_terseLabel_en-US" xlink:label="lab_us-gaap_FiniteLivedIntangibleAssetsByMajorClassAxis" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Finite-Lived Intangible Assets by Major Class [Axis]</link:label>
    <link:label id="lab_us-gaap_FiniteLivedIntangibleAssetsByMajorClassAxis_label_en-US" xlink:label="lab_us-gaap_FiniteLivedIntangibleAssetsByMajorClassAxis" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Finite-Lived Intangible Assets by Major Class [Axis]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsByMajorClassAxis" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_FiniteLivedIntangibleAssetsByMajorClassAxis"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsByMajorClassAxis" xlink:to="lab_us-gaap_FiniteLivedIntangibleAssetsByMajorClassAxis" xlink:type="arc" order="1"/>
    <link:label id="lab_slm_WithoutCosignerMember_e8db6250-18c5-4239-8ee0-ecbbb0e200b3_terseLabel_en-US" xlink:label="lab_slm_WithoutCosignerMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Without cosigner</link:label>
    <link:label id="lab_slm_WithoutCosignerMember_label_en-US" xlink:label="lab_slm_WithoutCosignerMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Without Cosigner [Member]</link:label>
    <link:label id="lab_slm_WithoutCosignerMember_documentation_en-US" xlink:label="lab_slm_WithoutCosignerMember" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Without Cosigner [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_slm_WithoutCosignerMember" xlink:href="slm-20230331.xsd#slm_WithoutCosignerMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_slm_WithoutCosignerMember" xlink:to="lab_slm_WithoutCosignerMember" xlink:type="arc" order="1"/>
    <link:label id="lab_slm_AllowanceForCreditLossesAbstract_b37b8609-fbc3-47aa-9a8c-7a83d9e7c859_terseLabel_en-US" xlink:label="lab_slm_AllowanceForCreditLossesAbstract" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Allowance for Credit Losses</link:label>
    <link:label id="lab_slm_AllowanceForCreditLossesAbstract_label_en-US" xlink:label="lab_slm_AllowanceForCreditLossesAbstract" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Allowance For Credit Losses [Abstract]</link:label>
    <link:label id="lab_slm_AllowanceForCreditLossesAbstract_documentation_en-US" xlink:label="lab_slm_AllowanceForCreditLossesAbstract" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Allowance for credit losses.</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_slm_AllowanceForCreditLossesAbstract" xlink:href="slm-20230331.xsd#slm_AllowanceForCreditLossesAbstract"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_slm_AllowanceForCreditLossesAbstract" xlink:to="lab_slm_AllowanceForCreditLossesAbstract" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_AdjustmentsRelatedToTaxWithholdingForShareBasedCompensation_7d3fb908-b4d9-4ce0-b401-be1e969a141a_negatedTerseLabel_en-US" xlink:label="lab_us-gaap_AdjustmentsRelatedToTaxWithholdingForShareBasedCompensation" xlink:role="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Shares repurchased related to employee stock-based compensation plans</link:label>
    <link:label id="lab_us-gaap_AdjustmentsRelatedToTaxWithholdingForShareBasedCompensation_label_en-US" xlink:label="lab_us-gaap_AdjustmentsRelatedToTaxWithholdingForShareBasedCompensation" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Share-Based Payment Arrangement, Decrease for Tax Withholding Obligation</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AdjustmentsRelatedToTaxWithholdingForShareBasedCompensation" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AdjustmentsRelatedToTaxWithholdingForShareBasedCompensation"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_AdjustmentsRelatedToTaxWithholdingForShareBasedCompensation" xlink:to="lab_us-gaap_AdjustmentsRelatedToTaxWithholdingForShareBasedCompensation" xlink:type="arc" order="1"/>
    <link:label id="lab_slm_AllowanceAbstract_dcdaecae-a052-4a16-99b9-0917feea10af_terseLabel_en-US" xlink:label="lab_slm_AllowanceAbstract" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Allowance</link:label>
    <link:label id="lab_slm_AllowanceAbstract_label_en-US" xlink:label="lab_slm_AllowanceAbstract" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Allowance [Abstract]</link:label>
    <link:label id="lab_slm_AllowanceAbstract_documentation_en-US" xlink:label="lab_slm_AllowanceAbstract" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Allowance.</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_slm_AllowanceAbstract" xlink:href="slm-20230331.xsd#slm_AllowanceAbstract"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_slm_AllowanceAbstract" xlink:to="lab_slm_AllowanceAbstract" xlink:type="arc" order="1"/>
    <link:label id="lab_slm_AllowanceAsPercentageOfEndingLoanBalanceAndAccuredInterest_ed8b1269-9e41-4aae-9cf4-e440ea5aa6e7_terseLabel_en-US" xlink:label="lab_slm_AllowanceAsPercentageOfEndingLoanBalanceAndAccuredInterest" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Allowance as a percentage of the ending total loan balance and accrued interest to be capitalized(5)</link:label>
    <link:label id="lab_slm_AllowanceAsPercentageOfEndingLoanBalanceAndAccuredInterest_label_en-US" xlink:label="lab_slm_AllowanceAsPercentageOfEndingLoanBalanceAndAccuredInterest" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Allowance As Percentage Of Ending Loan Balance And Accured Interest</link:label>
    <link:label id="lab_slm_AllowanceAsPercentageOfEndingLoanBalanceAndAccuredInterest_documentation_en-US" xlink:label="lab_slm_AllowanceAsPercentageOfEndingLoanBalanceAndAccuredInterest" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Allowance As Percentage Of Ending Loan Balance And Accured Interest</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_slm_AllowanceAsPercentageOfEndingLoanBalanceAndAccuredInterest" xlink:href="slm-20230331.xsd#slm_AllowanceAsPercentageOfEndingLoanBalanceAndAccuredInterest"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_slm_AllowanceAsPercentageOfEndingLoanBalanceAndAccuredInterest" xlink:to="lab_slm_AllowanceAsPercentageOfEndingLoanBalanceAndAccuredInterest" xlink:type="arc" order="1"/>
    <link:label id="lab_dei_CityAreaCode_2b8b53ea-d650-4b7f-a629-785e3e544f3e_terseLabel_en-US" xlink:label="lab_dei_CityAreaCode" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">City Area Code</link:label>
    <link:label id="lab_dei_CityAreaCode_label_en-US" xlink:label="lab_dei_CityAreaCode" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">City Area Code</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_dei_CityAreaCode" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_CityAreaCode"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_dei_CityAreaCode" xlink:to="lab_dei_CityAreaCode" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_AssetsAbstract_4ee89983-6c06-437a-8b80-466d43d6bb1a_terseLabel_en-US" xlink:label="lab_us-gaap_AssetsAbstract" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Assets</link:label>
    <link:label id="lab_us-gaap_AssetsAbstract_label_en-US" xlink:label="lab_us-gaap_AssetsAbstract" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Assets [Abstract]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AssetsAbstract" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AssetsAbstract"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_AssetsAbstract" xlink:to="lab_us-gaap_AssetsAbstract" xlink:type="arc" order="1"/>
    <link:label id="lab_slm_StockRepurchaseProgramNumberOfAdditionalSharesAuthorizedToBeRepurchased_e1c8f574-3bff-41f9-8d76-23a3fd73f6ba_terseLabel_en-US" xlink:label="lab_slm_StockRepurchaseProgramNumberOfAdditionalSharesAuthorizedToBeRepurchased" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Increase in amount of common stock that may be repurchased</link:label>
    <link:label id="lab_slm_StockRepurchaseProgramNumberOfAdditionalSharesAuthorizedToBeRepurchased_label_en-US" xlink:label="lab_slm_StockRepurchaseProgramNumberOfAdditionalSharesAuthorizedToBeRepurchased" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Stock Repurchase Program, Number of Additional Shares Authorized to be Repurchased</link:label>
    <link:label id="lab_slm_StockRepurchaseProgramNumberOfAdditionalSharesAuthorizedToBeRepurchased_documentation_en-US" xlink:label="lab_slm_StockRepurchaseProgramNumberOfAdditionalSharesAuthorizedToBeRepurchased" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Stock Repurchase Program, Number of Additional Shares Authorized to be Repurchased</link:label>
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    <link:label id="lab_us-gaap_LinesOfCreditCurrent_052499c7-0119-4c2c-9825-91c8d71140cb_terseLabel_en-US" xlink:label="lab_us-gaap_LinesOfCreditCurrent" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Secured borrowings outstanding</link:label>
    <link:label id="lab_us-gaap_LinesOfCreditCurrent_label_en-US" xlink:label="lab_us-gaap_LinesOfCreditCurrent" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Line of Credit, Current</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LinesOfCreditCurrent" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_LinesOfCreditCurrent"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_LinesOfCreditCurrent" xlink:to="lab_us-gaap_LinesOfCreditCurrent" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_NoninterestBearingDepositLiabilities_ad380cec-76ce-49b6-8804-4ff9b7b4bbd2_terseLabel_en-US" xlink:label="lab_us-gaap_NoninterestBearingDepositLiabilities" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Deposits - non-interest-bearing</link:label>
    <link:label id="lab_us-gaap_NoninterestBearingDepositLiabilities_label_en-US" xlink:label="lab_us-gaap_NoninterestBearingDepositLiabilities" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Noninterest-Bearing Deposit Liabilities</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NoninterestBearingDepositLiabilities" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_NoninterestBearingDepositLiabilities"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_NoninterestBearingDepositLiabilities" xlink:to="lab_us-gaap_NoninterestBearingDepositLiabilities" xlink:type="arc" order="1"/>
    <link:label id="lab_slm_TierOneCommonEquityCapitaltoRiskWeightedAssets_3937c697-5a67-4f9b-8f7d-749946256010_terseLabel_en-US" xlink:label="lab_slm_TierOneCommonEquityCapitaltoRiskWeightedAssets" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Common Equity Tier 1 Capital (to Risk-Weighted Assets)</link:label>
    <link:label id="lab_slm_TierOneCommonEquityCapitaltoRiskWeightedAssets_label_en-US" xlink:label="lab_slm_TierOneCommonEquityCapitaltoRiskWeightedAssets" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Tier One Common Equity Capital to Risk Weighted Assets</link:label>
    <link:label id="lab_slm_TierOneCommonEquityCapitaltoRiskWeightedAssets_documentation_en-US" xlink:label="lab_slm_TierOneCommonEquityCapitaltoRiskWeightedAssets" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Tier One Common Equity Capital to Risk Weighted Assets</link:label>
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    <link:label id="lab_us-gaap_InterestExpenseAbstract_c158e85d-0f35-4374-b6ed-75402a45559f_terseLabel_en-US" xlink:label="lab_us-gaap_InterestExpenseAbstract" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Interest expense:</link:label>
    <link:label id="lab_us-gaap_InterestExpenseAbstract_label_en-US" xlink:label="lab_us-gaap_InterestExpenseAbstract" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Interest Expense [Abstract]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestExpenseAbstract" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_InterestExpenseAbstract"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_InterestExpenseAbstract" xlink:to="lab_us-gaap_InterestExpenseAbstract" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_MortgageBackedSecuritiesMember_b83754f0-14c7-413d-ab90-db5f6fe566fd_terseLabel_en-US" xlink:label="lab_us-gaap_MortgageBackedSecuritiesMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Mortgage-backed securities</link:label>
    <link:label id="lab_us-gaap_MortgageBackedSecuritiesMember_label_en-US" xlink:label="lab_us-gaap_MortgageBackedSecuritiesMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Collateralized Mortgage-Backed Securities [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_MortgageBackedSecuritiesMember" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_MortgageBackedSecuritiesMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_MortgageBackedSecuritiesMember" xlink:to="lab_us-gaap_MortgageBackedSecuritiesMember" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_FinancialLiabilitiesFairValueDisclosure_7e452aa9-1625-4404-88d7-bd3ea30794d3_totalLabel_en-US" xlink:label="lab_us-gaap_FinancialLiabilitiesFairValueDisclosure" xlink:role="http://www.xbrl.org/2003/role/totalLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Total interest-bearing liabilities</link:label>
    <link:label id="lab_us-gaap_FinancialLiabilitiesFairValueDisclosure_label_en-US" xlink:label="lab_us-gaap_FinancialLiabilitiesFairValueDisclosure" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Financial Liabilities Fair Value Disclosure</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinancialLiabilitiesFairValueDisclosure" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_FinancialLiabilitiesFairValueDisclosure"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_FinancialLiabilitiesFairValueDisclosure" xlink:to="lab_us-gaap_FinancialLiabilitiesFairValueDisclosure" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_FairValueByAssetClassAxis_a5f54e57-3553-47ad-a900-027d38246274_terseLabel_en-US" xlink:label="lab_us-gaap_FairValueByAssetClassAxis" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Asset Class [Axis]</link:label>
    <link:label id="lab_us-gaap_FairValueByAssetClassAxis_label_en-US" xlink:label="lab_us-gaap_FairValueByAssetClassAxis" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Asset Class [Axis]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueByAssetClassAxis" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_FairValueByAssetClassAxis"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_FairValueByAssetClassAxis" xlink:to="lab_us-gaap_FairValueByAssetClassAxis" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_ShareBasedCompensation_b67e74a2-6815-496d-b9ca-d7abec57cbce_verboseLabel_en-US" xlink:label="lab_us-gaap_ShareBasedCompensation" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Stock-based compensation expense</link:label>
    <link:label id="lab_us-gaap_ShareBasedCompensation_label_en-US" xlink:label="lab_us-gaap_ShareBasedCompensation" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Share-Based Payment Arrangement, Noncash Expense</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensation" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ShareBasedCompensation"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_ShareBasedCompensation" xlink:to="lab_us-gaap_ShareBasedCompensation" xlink:type="arc" order="1"/>
    <link:label id="lab_slm_NetUnamortizedPremiumOrDiscountOriginatedInCurrentFiscalYear_f4c4f466-cd49-40eb-80d4-45312a588a6c_terseLabel_en-US" xlink:label="lab_slm_NetUnamortizedPremiumOrDiscountOriginatedInCurrentFiscalYear" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Private Education Loans deferred origination costs and unamortized premium/(discount), Year 1</link:label>
    <link:label id="lab_slm_NetUnamortizedPremiumOrDiscountOriginatedInCurrentFiscalYear_label_en-US" xlink:label="lab_slm_NetUnamortizedPremiumOrDiscountOriginatedInCurrentFiscalYear" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Net Unamortized Premium Or Discount, Originated In Current Fiscal Year</link:label>
    <link:label id="lab_slm_NetUnamortizedPremiumOrDiscountOriginatedInCurrentFiscalYear_documentation_en-US" xlink:label="lab_slm_NetUnamortizedPremiumOrDiscountOriginatedInCurrentFiscalYear" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Net Unamortized Premium Or Discount, Originated In Current Fiscal Year</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_slm_NetUnamortizedPremiumOrDiscountOriginatedInCurrentFiscalYear" xlink:href="slm-20230331.xsd#slm_NetUnamortizedPremiumOrDiscountOriginatedInCurrentFiscalYear"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_slm_NetUnamortizedPremiumOrDiscountOriginatedInCurrentFiscalYear" xlink:to="lab_slm_NetUnamortizedPremiumOrDiscountOriginatedInCurrentFiscalYear" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_VariableRateAxis_c6b1404e-4f00-44fd-8c42-24be67c531fc_terseLabel_en-US" xlink:label="lab_us-gaap_VariableRateAxis" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Variable Rate [Axis]</link:label>
    <link:label id="lab_us-gaap_VariableRateAxis_label_en-US" xlink:label="lab_us-gaap_VariableRateAxis" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Variable Rate [Axis]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_VariableRateAxis" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_VariableRateAxis"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_VariableRateAxis" xlink:to="lab_us-gaap_VariableRateAxis" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_NoninterestExpense_1c98b7c8-f76f-48eb-ab0d-988b032cccc5_totalLabel_en-US" xlink:label="lab_us-gaap_NoninterestExpense" xlink:role="http://www.xbrl.org/2003/role/totalLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Total non-interest expenses</link:label>
    <link:label id="lab_us-gaap_NoninterestExpense_label_en-US" xlink:label="lab_us-gaap_NoninterestExpense" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Noninterest Expense</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NoninterestExpense" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_NoninterestExpense"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_NoninterestExpense" xlink:to="lab_us-gaap_NoninterestExpense" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_OffBalanceSheetCreditLossLiability_d09d44d6-7799-4b1b-8f47-701ebb84118f_periodStartLabel_en-US" xlink:label="lab_us-gaap_OffBalanceSheetCreditLossLiability" xlink:role="http://www.xbrl.org/2003/role/periodStartLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Beginning balance</link:label>
    <link:label id="lab_us-gaap_OffBalanceSheetCreditLossLiability_d55e0166-e48b-465f-b015-7329a457f38b_periodEndLabel_en-US" xlink:label="lab_us-gaap_OffBalanceSheetCreditLossLiability" xlink:role="http://www.xbrl.org/2003/role/periodEndLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Ending balance</link:label>
    <link:label id="lab_us-gaap_OffBalanceSheetCreditLossLiability_89a64db8-3094-419e-98ca-130c3056f947_verboseLabel_en-US" xlink:label="lab_us-gaap_OffBalanceSheetCreditLossLiability" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Total Exposure</link:label>
    <link:label id="lab_us-gaap_OffBalanceSheetCreditLossLiability_f2357e14-b406-4d07-a312-c4a1e54351e8_terseLabel_en-US" xlink:label="lab_us-gaap_OffBalanceSheetCreditLossLiability" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Liability for unfunded commitments</link:label>
    <link:label id="lab_us-gaap_OffBalanceSheetCreditLossLiability_label_en-US" xlink:label="lab_us-gaap_OffBalanceSheetCreditLossLiability" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Off-Balance-Sheet, Credit Loss, Liability</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OffBalanceSheetCreditLossLiability" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_OffBalanceSheetCreditLossLiability"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_OffBalanceSheetCreditLossLiability" xlink:to="lab_us-gaap_OffBalanceSheetCreditLossLiability" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_IncreaseDecreaseInOtherOperatingLiabilities_a8891da0-51f2-42cb-8975-20bcb5511b41_terseLabel_en-US" xlink:label="lab_us-gaap_IncreaseDecreaseInOtherOperatingLiabilities" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Decrease in other liabilities</link:label>
    <link:label id="lab_us-gaap_IncreaseDecreaseInOtherOperatingLiabilities_label_en-US" xlink:label="lab_us-gaap_IncreaseDecreaseInOtherOperatingLiabilities" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Increase (Decrease) in Other Operating Liabilities</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInOtherOperatingLiabilities" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_IncreaseDecreaseInOtherOperatingLiabilities"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_IncreaseDecreaseInOtherOperatingLiabilities" xlink:to="lab_us-gaap_IncreaseDecreaseInOtherOperatingLiabilities" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_TierOneLeverageCapitalAbstract_00d6e373-5b16-4cb8-a9d1-49eeb04cdc10_verboseLabel_en-US" xlink:label="lab_us-gaap_TierOneLeverageCapitalAbstract" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">U.S. Basel III Regulatory Requirements, Amount</link:label>
    <link:label id="lab_us-gaap_TierOneLeverageCapitalAbstract_label_en-US" xlink:label="lab_us-gaap_TierOneLeverageCapitalAbstract" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Banking Regulation, Tier 1 Leverage Capital [Abstract]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_TierOneLeverageCapitalAbstract" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_TierOneLeverageCapitalAbstract"/>
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    <link:label id="lab_slm_FairValueDisclosureOffBalanceSheetRisksAmountLiabilityOther_13470b42-d54d-4fa2-9499-0f2074cace56_terseLabel_en-US" xlink:label="lab_slm_FairValueDisclosureOffBalanceSheetRisksAmountLiabilityOther" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Other provision items</link:label>
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    <link:label id="lab_us-gaap_ConsumerPortfolioSegmentMember_f1f502d9-47cb-489d-a42f-da2d756e0440_terseLabel_en-US" xlink:label="lab_us-gaap_ConsumerPortfolioSegmentMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Consumer Portfolio Segment</link:label>
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    <link:label id="lab_us-gaap_ScheduleOfEarningsPerShareBasicAndDilutedTableTextBlock_65728b2d-0433-4824-b0ba-0a80875be037_terseLabel_en-US" xlink:label="lab_us-gaap_ScheduleOfEarningsPerShareBasicAndDilutedTableTextBlock" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Schedule of Earnings Per Share, Basic and Diluted</link:label>
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    <link:label id="lab_slm_NetUnamortizedPremiumOrDiscountBeforeAllowanceForCreditLoss_4997857d-b4ba-4288-855f-086036a201b3_totalLabel_en-US" xlink:label="lab_slm_NetUnamortizedPremiumOrDiscountBeforeAllowanceForCreditLoss" xlink:role="http://www.xbrl.org/2003/role/totalLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Private Education Loans deferred origination costs and unamortized premium/(discount), Total</link:label>
    <link:label id="lab_slm_NetUnamortizedPremiumOrDiscountBeforeAllowanceForCreditLoss_label_en-US" xlink:label="lab_slm_NetUnamortizedPremiumOrDiscountBeforeAllowanceForCreditLoss" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Net Unamortized Premium Or Discount, Before Allowance For Credit Loss</link:label>
    <link:label id="lab_slm_NetUnamortizedPremiumOrDiscountBeforeAllowanceForCreditLoss_documentation_en-US" xlink:label="lab_slm_NetUnamortizedPremiumOrDiscountBeforeAllowanceForCreditLoss" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Net Unamortized Premium Or Discount, Before Allowance For Credit Loss</link:label>
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    <link:label id="lab_us-gaap_TradingSecuritiesDebtAmortizedCost_f8a6debf-059c-4854-ac49-71dd165dc889_terseLabel_en-US" xlink:label="lab_us-gaap_TradingSecuritiesDebtAmortizedCost" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Trading investments, cost</link:label>
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    <link:label id="lab_us-gaap_PaymentsToAcquireInterestInSubsidiariesAndAffiliates_ab031352-7fec-4da0-b9b5-c18f08d80a7e_negatedTerseLabel_en-US" xlink:label="lab_us-gaap_PaymentsToAcquireInterestInSubsidiariesAndAffiliates" xlink:role="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Purchase of subsidiary, net of cash acquired</link:label>
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    <link:label id="lab_us-gaap_OffsettingAssetsTableTextBlock_8b9f0e5f-86fd-4c1e-9346-151fe8ca872b_terseLabel_en-US" xlink:label="lab_us-gaap_OffsettingAssetsTableTextBlock" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Schedule of Offsetting Assets</link:label>
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    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OffsettingAssetsTableTextBlock" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_OffsettingAssetsTableTextBlock"/>
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    <link:label id="lab_slm_LoansGrossOriginatedInCurrentFiscalYear_54624b7f-2483-4187-8cbf-486cfe98440a_terseLabel_en-US" xlink:label="lab_slm_LoansGrossOriginatedInCurrentFiscalYear" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Total Private Education Loans, gross, Year 1</link:label>
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    <link:label id="lab_slm_PrivateEducationLoansSecuritizedIn2022Member_19c44613-dbd9-41eb-b4dd-6bf1ff9c34f5_terseLabel_en-US" xlink:label="lab_slm_PrivateEducationLoansSecuritizedIn2022Member" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Private Education Loans Securitized in 2022</link:label>
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    <link:label id="lab_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_da040b88-0f49-48b1-9823-9cbf2c203b76_terseLabel_en-US" xlink:label="lab_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Increase (Decrease) in Stockholders' Equity [Roll Forward]</link:label>
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    <link:label id="lab_us-gaap_VariableInterestEntityPrimaryBeneficiaryMember_c8ebe894-4dc4-4cf5-b033-36b207f469de_terseLabel_en-US" xlink:label="lab_us-gaap_VariableInterestEntityPrimaryBeneficiaryMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Variable Interest Entity, Primary Beneficiary</link:label>
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    <link:label id="lab_slm_LoansGrossOriginatedTwoYearsBeforeLatestFiscalYear_ae8aa14b-cd69-4a19-8158-272218b579c6_terseLabel_en-US" xlink:label="lab_slm_LoansGrossOriginatedTwoYearsBeforeLatestFiscalYear" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Total Private Education Loans, gross, Year 3</link:label>
    <link:label id="lab_slm_LoansGrossOriginatedTwoYearsBeforeLatestFiscalYear_label_en-US" xlink:label="lab_slm_LoansGrossOriginatedTwoYearsBeforeLatestFiscalYear" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Loans Gross, Originated Two Years Before Latest Fiscal Year</link:label>
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    <link:label id="lab_slm_WeightedAverageInterestRateonLoans_d64b043b-132a-44de-9cea-fabd8f65ff09_terseLabel_en-US" xlink:label="lab_slm_WeightedAverageInterestRateonLoans" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Weighted Average Interest Rate</link:label>
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    <link:label id="lab_slm_SchoolFICORefreshedAmountsMember_710cb9fb-8ab6-4c4e-9b4c-e389112069a2_terseLabel_en-US" xlink:label="lab_slm_SchoolFICORefreshedAmountsMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">FICO Refreshed</link:label>
    <link:label id="lab_slm_SchoolFICORefreshedAmountsMember_label_en-US" xlink:label="lab_slm_SchoolFICORefreshedAmountsMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">School FICO, Refreshed Amounts [Member]</link:label>
    <link:label id="lab_slm_SchoolFICORefreshedAmountsMember_documentation_en-US" xlink:label="lab_slm_SchoolFICORefreshedAmountsMember" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">School FICO, Refreshed Amounts [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_slm_SchoolFICORefreshedAmountsMember" xlink:href="slm-20230331.xsd#slm_SchoolFICORefreshedAmountsMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_slm_SchoolFICORefreshedAmountsMember" xlink:to="lab_slm_SchoolFICORefreshedAmountsMember" xlink:type="arc" order="1"/>
    <link:label id="lab_dei_EntityAddressPostalZipCode_1f0e7ae6-7cbd-4ee3-b149-f52fbdb1f987_terseLabel_en-US" xlink:label="lab_dei_EntityAddressPostalZipCode" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Entity Address, Postal Zip Code</link:label>
    <link:label id="lab_dei_EntityAddressPostalZipCode_label_en-US" xlink:label="lab_dei_EntityAddressPostalZipCode" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Entity Address, Postal Zip Code</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityAddressPostalZipCode" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_EntityAddressPostalZipCode"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_dei_EntityAddressPostalZipCode" xlink:to="lab_dei_EntityAddressPostalZipCode" xlink:type="arc" order="1"/>
    <link:label id="lab_slm_NumeratorAbstract_47b59b9a-9adb-494b-99f3-0510fd23471e_terseLabel_en-US" xlink:label="lab_slm_NumeratorAbstract" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Numerator:</link:label>
    <link:label id="lab_slm_NumeratorAbstract_label_en-US" xlink:label="lab_slm_NumeratorAbstract" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Numerator [Abstract]</link:label>
    <link:label id="lab_slm_NumeratorAbstract_documentation_en-US" xlink:label="lab_slm_NumeratorAbstract" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Numerator.</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_slm_NumeratorAbstract" xlink:href="slm-20230331.xsd#slm_NumeratorAbstract"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_slm_NumeratorAbstract" xlink:to="lab_slm_NumeratorAbstract" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_InvestmentsFairValueDisclosure_b213d8a2-1e35-4d4e-8c6d-009059bb0240_terseLabel_en-US" xlink:label="lab_us-gaap_InvestmentsFairValueDisclosure" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Available-for-sale investments</link:label>
    <link:label id="lab_us-gaap_InvestmentsFairValueDisclosure_label_en-US" xlink:label="lab_us-gaap_InvestmentsFairValueDisclosure" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Investments, Fair Value Disclosure</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InvestmentsFairValueDisclosure" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_InvestmentsFairValueDisclosure"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_InvestmentsFairValueDisclosure" xlink:to="lab_us-gaap_InvestmentsFairValueDisclosure" xlink:type="arc" order="1"/>
    <link:label id="lab_slm_AffordableHousingTaxCreditsandOtherTaxBenefitsPercentage_890d047f-87f5-4e75-b2b3-b311e8067f1e_terseLabel_en-US" xlink:label="lab_slm_AffordableHousingTaxCreditsandOtherTaxBenefitsPercentage" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Low income housing tax credit investments, expected tax benefits recognized</link:label>
    <link:label id="lab_slm_AffordableHousingTaxCreditsandOtherTaxBenefitsPercentage_label_en-US" xlink:label="lab_slm_AffordableHousingTaxCreditsandOtherTaxBenefitsPercentage" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Affordable Housing Tax Credits and Other Tax Benefits, Percentage</link:label>
    <link:label id="lab_slm_AffordableHousingTaxCreditsandOtherTaxBenefitsPercentage_documentation_en-US" xlink:label="lab_slm_AffordableHousingTaxCreditsandOtherTaxBenefitsPercentage" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Affordable Housing Tax Credits and Other Tax Benefits, Percentage</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_slm_AffordableHousingTaxCreditsandOtherTaxBenefitsPercentage" xlink:href="slm-20230331.xsd#slm_AffordableHousingTaxCreditsandOtherTaxBenefitsPercentage"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_slm_AffordableHousingTaxCreditsandOtherTaxBenefitsPercentage" xlink:to="lab_slm_AffordableHousingTaxCreditsandOtherTaxBenefitsPercentage" xlink:type="arc" order="1"/>
    <link:label id="lab_slm_DerivativeInstrumentsIncreaseDecreaseInFairValueOfFutureInterestPaymentsRecordedInEarnings_9c5aff1c-f48e-40fd-9f98-43c32ad773b4_terseLabel_en-US" xlink:label="lab_slm_DerivativeInstrumentsIncreaseDecreaseInFairValueOfFutureInterestPaymentsRecordedInEarnings" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Change in fair value of future interest payments recorded in earnings</link:label>
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    <link:loc xlink:type="locator" xlink:label="loc_slm_DerivativeInstrumentsIncreaseDecreaseInFairValueOfFutureInterestPaymentsRecordedInEarnings" xlink:href="slm-20230331.xsd#slm_DerivativeInstrumentsIncreaseDecreaseInFairValueOfFutureInterestPaymentsRecordedInEarnings"/>
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    <link:label id="lab_us-gaap_LineOfCreditFacilityMaximumBorrowingCapacity_4ee1c235-a1ab-4fd2-976b-6a5ff6fea574_terseLabel_en-US" xlink:label="lab_us-gaap_LineOfCreditFacilityMaximumBorrowingCapacity" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Secured borrowing facility maximum borrowing capacity</link:label>
    <link:label id="lab_us-gaap_LineOfCreditFacilityMaximumBorrowingCapacity_label_en-US" xlink:label="lab_us-gaap_LineOfCreditFacilityMaximumBorrowingCapacity" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Line of Credit Facility, Maximum Borrowing Capacity</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LineOfCreditFacilityMaximumBorrowingCapacity" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_LineOfCreditFacilityMaximumBorrowingCapacity"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_LineOfCreditFacilityMaximumBorrowingCapacity" xlink:to="lab_us-gaap_LineOfCreditFacilityMaximumBorrowingCapacity" xlink:type="arc" order="1"/>
    <link:label id="lab_slm_PrivateEducationLoansGrossPercentage_43f0e88b-6006-46c7-8d16-9b6f93d25840_totalLabel_en-US" xlink:label="lab_slm_PrivateEducationLoansGrossPercentage" xlink:role="http://www.xbrl.org/2003/role/totalLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Total in percent</link:label>
    <link:label id="lab_slm_PrivateEducationLoansGrossPercentage_label_en-US" xlink:label="lab_slm_PrivateEducationLoansGrossPercentage" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Private Education Loans Gross, Percentage</link:label>
    <link:label id="lab_slm_PrivateEducationLoansGrossPercentage_documentation_en-US" xlink:label="lab_slm_PrivateEducationLoansGrossPercentage" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Private education loans gross in percent.</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_slm_PrivateEducationLoansGrossPercentage" xlink:href="slm-20230331.xsd#slm_PrivateEducationLoansGrossPercentage"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_slm_PrivateEducationLoansGrossPercentage" xlink:to="lab_slm_PrivateEducationLoansGrossPercentage" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_DerivativeAssetCollateralObligationToReturnCashOffset_4599d5e4-08b0-46ab-b311-9c3a2e42ca87_terseLabel_en-US" xlink:label="lab_us-gaap_DerivativeAssetCollateralObligationToReturnCashOffset" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Cash collateral pledged</link:label>
    <link:label id="lab_us-gaap_DerivativeAssetCollateralObligationToReturnCashOffset_label_en-US" xlink:label="lab_us-gaap_DerivativeAssetCollateralObligationToReturnCashOffset" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Derivative Asset, Subject to Master Netting Arrangement, Collateral, Obligation to Return Cash, Offset Against Derivative Asset</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeAssetCollateralObligationToReturnCashOffset" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_DerivativeAssetCollateralObligationToReturnCashOffset"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_DerivativeAssetCollateralObligationToReturnCashOffset" xlink:to="lab_us-gaap_DerivativeAssetCollateralObligationToReturnCashOffset" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_FederalDepositInsuranceCorporationPremiumExpense_a65f2c4a-6d8e-4de8-ba90-4011c19b75b5_terseLabel_en-US" xlink:label="lab_us-gaap_FederalDepositInsuranceCorporationPremiumExpense" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">FDIC assessment fees</link:label>
    <link:label id="lab_us-gaap_FederalDepositInsuranceCorporationPremiumExpense_label_en-US" xlink:label="lab_us-gaap_FederalDepositInsuranceCorporationPremiumExpense" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Federal Deposit Insurance Corporation Premium Expense</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FederalDepositInsuranceCorporationPremiumExpense" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_FederalDepositInsuranceCorporationPremiumExpense"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_FederalDepositInsuranceCorporationPremiumExpense" xlink:to="lab_us-gaap_FederalDepositInsuranceCorporationPremiumExpense" xlink:type="arc" order="1"/>
    <link:label id="lab_slm_LoansInRepaymentBeforeAllowanceForCreditLoss_8028ffb5-7955-4de0-9e51-f5752a2ae152_totalLabel_en-US" xlink:label="lab_slm_LoansInRepaymentBeforeAllowanceForCreditLoss" xlink:role="http://www.xbrl.org/2003/role/totalLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Private Education Loans in forbearance, total</link:label>
    <link:label id="lab_slm_LoansInRepaymentBeforeAllowanceForCreditLoss_label_en-US" xlink:label="lab_slm_LoansInRepaymentBeforeAllowanceForCreditLoss" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Loans In Repayment, Before Allowance For Credit Loss</link:label>
    <link:label id="lab_slm_LoansInRepaymentBeforeAllowanceForCreditLoss_documentation_en-US" xlink:label="lab_slm_LoansInRepaymentBeforeAllowanceForCreditLoss" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Loans In Repayment, Before Allowance For Credit Loss</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_slm_LoansInRepaymentBeforeAllowanceForCreditLoss" xlink:href="slm-20230331.xsd#slm_LoansInRepaymentBeforeAllowanceForCreditLoss"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_slm_LoansInRepaymentBeforeAllowanceForCreditLoss" xlink:to="lab_slm_LoansInRepaymentBeforeAllowanceForCreditLoss" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_FinancingReceivablesPeriodPastDueDomain_efb124c2-a8c9-4f99-90cc-f0decf107e84_terseLabel_en-US" xlink:label="lab_us-gaap_FinancingReceivablesPeriodPastDueDomain" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Financial Asset, Period Past Due [Domain]</link:label>
    <link:label id="lab_us-gaap_FinancingReceivablesPeriodPastDueDomain_label_en-US" xlink:label="lab_us-gaap_FinancingReceivablesPeriodPastDueDomain" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Financial Asset, Aging [Domain]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinancingReceivablesPeriodPastDueDomain" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_FinancingReceivablesPeriodPastDueDomain"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_FinancingReceivablesPeriodPastDueDomain" xlink:to="lab_us-gaap_FinancingReceivablesPeriodPastDueDomain" xlink:type="arc" order="1"/>
    <link:label id="lab_srt_RangeMember_f73f77fc-f18a-4085-8344-37c7c7e39a69_terseLabel_en-US" xlink:label="lab_srt_RangeMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Statistical Measurement [Domain]</link:label>
    <link:label id="lab_srt_RangeMember_label_en-US" xlink:label="lab_srt_RangeMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Statistical Measurement [Domain]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_srt_RangeMember" xlink:href="https://xbrl.fasb.org/srt/2022/elts/srt-2022.xsd#srt_RangeMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_srt_RangeMember" xlink:to="lab_srt_RangeMember" xlink:type="arc" order="1"/>
    <link:label id="lab_slm_DebtSecuritiesAvailableForSaleNumberOfPositions_031e4bad-2027-4a0f-b7e9-cf9898049994_terseLabel_en-US" xlink:label="lab_slm_DebtSecuritiesAvailableForSaleNumberOfPositions" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Number of mortgage-backed securities</link:label>
    <link:label id="lab_slm_DebtSecuritiesAvailableForSaleNumberOfPositions_label_en-US" xlink:label="lab_slm_DebtSecuritiesAvailableForSaleNumberOfPositions" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Debt Securities, Available-for-sale, Number of Positions</link:label>
    <link:label id="lab_slm_DebtSecuritiesAvailableForSaleNumberOfPositions_documentation_en-US" xlink:label="lab_slm_DebtSecuritiesAvailableForSaleNumberOfPositions" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Debt Securities, Available-for-sale, Number of Positions</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_slm_DebtSecuritiesAvailableForSaleNumberOfPositions" xlink:href="slm-20230331.xsd#slm_DebtSecuritiesAvailableForSaleNumberOfPositions"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_slm_DebtSecuritiesAvailableForSaleNumberOfPositions" xlink:to="lab_slm_DebtSecuritiesAvailableForSaleNumberOfPositions" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_InterestExpenseDeposits_61ec167c-a6e0-4155-a8f0-e0c06a24420f_terseLabel_en-US" xlink:label="lab_us-gaap_InterestExpenseDeposits" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Deposits</link:label>
    <link:label id="lab_us-gaap_InterestExpenseDeposits_label_en-US" xlink:label="lab_us-gaap_InterestExpenseDeposits" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Interest Expense, Deposits</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestExpenseDeposits" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_InterestExpenseDeposits"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_InterestExpenseDeposits" xlink:to="lab_us-gaap_InterestExpenseDeposits" xlink:type="arc" order="1"/>
    <link:label id="lab_slm_FICOscore670699Member_5979e571-7af7-43ca-9fab-48cdbc65d0e7_terseLabel_en-US" xlink:label="lab_slm_FICOscore670699Member" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">670-699</link:label>
    <link:label id="lab_slm_FICOscore670699Member_label_en-US" xlink:label="lab_slm_FICOscore670699Member" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">FICO score 670-699 [Member]</link:label>
    <link:label id="lab_slm_FICOscore670699Member_documentation_en-US" xlink:label="lab_slm_FICOscore670699Member" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">FICO score 670-699 [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_slm_FICOscore670699Member" xlink:href="slm-20230331.xsd#slm_FICOscore670699Member"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_slm_FICOscore670699Member" xlink:to="lab_slm_FICOscore670699Member" xlink:type="arc" order="1"/>
    <link:label id="lab_slm_FinancingReceivableAccruedInterestOriginationVintageOriginatedTwoYearsBeforeLatestFiscalYear_ac618b91-2d38-40cf-af86-2f39182c9fae_terseLabel_en-US" xlink:label="lab_slm_FinancingReceivableAccruedInterestOriginationVintageOriginatedTwoYearsBeforeLatestFiscalYear" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Total accrued interest by origination vintage, Year 3</link:label>
    <link:label id="lab_slm_FinancingReceivableAccruedInterestOriginationVintageOriginatedTwoYearsBeforeLatestFiscalYear_label_en-US" xlink:label="lab_slm_FinancingReceivableAccruedInterestOriginationVintageOriginatedTwoYearsBeforeLatestFiscalYear" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Financing Receivable, Accrued interest, Origination Vintage, Originated Two Years before Latest Fiscal Year</link:label>
    <link:label id="lab_slm_FinancingReceivableAccruedInterestOriginationVintageOriginatedTwoYearsBeforeLatestFiscalYear_documentation_en-US" xlink:label="lab_slm_FinancingReceivableAccruedInterestOriginationVintageOriginatedTwoYearsBeforeLatestFiscalYear" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Financing Receivable, Accrued interest, Origination Vintage, Originated Two Years before Latest Fiscal Year</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_slm_FinancingReceivableAccruedInterestOriginationVintageOriginatedTwoYearsBeforeLatestFiscalYear" xlink:href="slm-20230331.xsd#slm_FinancingReceivableAccruedInterestOriginationVintageOriginatedTwoYearsBeforeLatestFiscalYear"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_slm_FinancingReceivableAccruedInterestOriginationVintageOriginatedTwoYearsBeforeLatestFiscalYear" xlink:to="lab_slm_FinancingReceivableAccruedInterestOriginationVintageOriginatedTwoYearsBeforeLatestFiscalYear" xlink:type="arc" order="1"/>
    <link:label id="lab_slm_AssetsFairValueDisclosureDifferenceBetweenCarryingValueandFairValue_e7464d08-55c7-423e-8c42-572fbf0ca88f_terseLabel_en-US" xlink:label="lab_slm_AssetsFairValueDisclosureDifferenceBetweenCarryingValueandFairValue" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Total earning assets, difference</link:label>
    <link:label id="lab_slm_AssetsFairValueDisclosureDifferenceBetweenCarryingValueandFairValue_label_en-US" xlink:label="lab_slm_AssetsFairValueDisclosureDifferenceBetweenCarryingValueandFairValue" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Assets, Fair Value Disclosure, Difference Between Carrying Value and Fair Value</link:label>
    <link:label id="lab_slm_AssetsFairValueDisclosureDifferenceBetweenCarryingValueandFairValue_documentation_en-US" xlink:label="lab_slm_AssetsFairValueDisclosureDifferenceBetweenCarryingValueandFairValue" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Assets, Fair Value Disclosure, Difference Between Carrying Value and Fair Value</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_slm_AssetsFairValueDisclosureDifferenceBetweenCarryingValueandFairValue" xlink:href="slm-20230331.xsd#slm_AssetsFairValueDisclosureDifferenceBetweenCarryingValueandFairValue"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_slm_AssetsFairValueDisclosureDifferenceBetweenCarryingValueandFairValue" xlink:to="lab_slm_AssetsFairValueDisclosureDifferenceBetweenCarryingValueandFairValue" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_TreasuryStockValueAcquiredCostMethod_64096786-8b69-44b0-9b0e-1466d8df123f_terseLabel_en-US" xlink:label="lab_us-gaap_TreasuryStockValueAcquiredCostMethod" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Common stock repurchased, amount</link:label>
    <link:label id="lab_us-gaap_TreasuryStockValueAcquiredCostMethod_label_en-US" xlink:label="lab_us-gaap_TreasuryStockValueAcquiredCostMethod" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Treasury Stock, Value, Acquired, Cost Method</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_TreasuryStockValueAcquiredCostMethod" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_TreasuryStockValueAcquiredCostMethod"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_TreasuryStockValueAcquiredCostMethod" xlink:to="lab_us-gaap_TreasuryStockValueAcquiredCostMethod" xlink:type="arc" order="1"/>
    <link:label id="lab_slm_AccruedInterestReceivableNotExpectedToBeCapitalized_4a3a1495-0c2e-462e-b7fe-607f2f66616c_terseLabel_en-US" xlink:label="lab_slm_AccruedInterestReceivableNotExpectedToBeCapitalized" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Accrued interest receivable not expected to be capitalized</link:label>
    <link:label id="lab_slm_AccruedInterestReceivableNotExpectedToBeCapitalized_label_en-US" xlink:label="lab_slm_AccruedInterestReceivableNotExpectedToBeCapitalized" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Accrued Interest Receivable Not Expected To Be Capitalized</link:label>
    <link:label id="lab_slm_AccruedInterestReceivableNotExpectedToBeCapitalized_documentation_en-US" xlink:label="lab_slm_AccruedInterestReceivableNotExpectedToBeCapitalized" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Accrued Interest Receivable Not Expected To Be Capitalized</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_slm_AccruedInterestReceivableNotExpectedToBeCapitalized" xlink:href="slm-20230331.xsd#slm_AccruedInterestReceivableNotExpectedToBeCapitalized"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_slm_AccruedInterestReceivableNotExpectedToBeCapitalized" xlink:to="lab_slm_AccruedInterestReceivableNotExpectedToBeCapitalized" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_NetIncomeLoss_b146b40b-5e93-4766-8342-4d501ecfa994_terseLabel_en-US" xlink:label="lab_us-gaap_NetIncomeLoss" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Net income</link:label>
    <link:label id="lab_us-gaap_NetIncomeLoss_label_en-US" xlink:label="lab_us-gaap_NetIncomeLoss" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Net Income (Loss) Attributable to Parent</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetIncomeLoss" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_NetIncomeLoss"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_NetIncomeLoss" xlink:to="lab_us-gaap_NetIncomeLoss" xlink:type="arc" order="1"/>
    <link:label id="lab_srt_CumulativeEffectPeriodOfAdoptionAxis_df33f211-9aef-4479-9da9-3da30b47510c_terseLabel_en-US" xlink:label="lab_srt_CumulativeEffectPeriodOfAdoptionAxis" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Cumulative Effect, Period Of Adoption [Axis]</link:label>
    <link:label id="lab_srt_CumulativeEffectPeriodOfAdoptionAxis_label_en-US" xlink:label="lab_srt_CumulativeEffectPeriodOfAdoptionAxis" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Cumulative Effect, Period of Adoption [Axis]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_srt_CumulativeEffectPeriodOfAdoptionAxis" xlink:href="https://xbrl.fasb.org/srt/2022/elts/srt-2022.xsd#srt_CumulativeEffectPeriodOfAdoptionAxis"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_srt_CumulativeEffectPeriodOfAdoptionAxis" xlink:to="lab_srt_CumulativeEffectPeriodOfAdoptionAxis" xlink:type="arc" order="1"/>
    <link:label id="lab_slm_CosignerMember_2b89420c-cfeb-42b1-8b98-54b4e937e76c_terseLabel_en-US" xlink:label="lab_slm_CosignerMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">With and without cosigners</link:label>
    <link:label id="lab_slm_CosignerMember_label_en-US" xlink:label="lab_slm_CosignerMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Cosigner [Member]</link:label>
    <link:label id="lab_slm_CosignerMember_documentation_en-US" xlink:label="lab_slm_CosignerMember" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Cosigner credit quality indicators that are developed and used internally by the company.</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_slm_CosignerMember" xlink:href="slm-20230331.xsd#slm_CosignerMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_slm_CosignerMember" xlink:to="lab_slm_CosignerMember" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_FixedIncomeInterestRateMember_45ca66a0-b81a-41c6-8603-b084c27707ef_verboseLabel_en-US" xlink:label="lab_us-gaap_FixedIncomeInterestRateMember" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Fixed-rate</link:label>
    <link:label id="lab_us-gaap_FixedIncomeInterestRateMember_9ec521f3-99f7-4379-a7c6-c7197151a8a4_terseLabel_en-US" xlink:label="lab_us-gaap_FixedIncomeInterestRateMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Fixed-rate</link:label>
    <link:label id="lab_us-gaap_FixedIncomeInterestRateMember_label_en-US" xlink:label="lab_us-gaap_FixedIncomeInterestRateMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Fixed Income Interest Rate [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FixedIncomeInterestRateMember" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_FixedIncomeInterestRateMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_FixedIncomeInterestRateMember" xlink:to="lab_us-gaap_FixedIncomeInterestRateMember" xlink:type="arc" order="1"/>
    <link:label id="lab_srt_StatementScenarioAxis_ea7ca038-66e3-4d43-99bf-ad3c32ecf421_terseLabel_en-US" xlink:label="lab_srt_StatementScenarioAxis" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Scenario [Axis]</link:label>
    <link:label id="lab_srt_StatementScenarioAxis_label_en-US" xlink:label="lab_srt_StatementScenarioAxis" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Scenario [Axis]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_srt_StatementScenarioAxis" xlink:href="https://xbrl.fasb.org/srt/2022/elts/srt-2022.xsd#srt_StatementScenarioAxis"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_srt_StatementScenarioAxis" xlink:to="lab_srt_StatementScenarioAxis" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_AssetsFairValueDisclosure_e11bd057-5ffe-4e60-81a7-50b5e74024e9_totalLabel_en-US" xlink:label="lab_us-gaap_AssetsFairValueDisclosure" xlink:role="http://www.xbrl.org/2003/role/totalLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Total earning assets</link:label>
    <link:label id="lab_us-gaap_AssetsFairValueDisclosure_label_en-US" xlink:label="lab_us-gaap_AssetsFairValueDisclosure" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Assets, Fair Value Disclosure</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AssetsFairValueDisclosure" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AssetsFairValueDisclosure"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_AssetsFairValueDisclosure" xlink:to="lab_us-gaap_AssetsFairValueDisclosure" xlink:type="arc" order="1"/>
    <link:label id="lab_slm_LoansOriginatedInCurrentFiscalYear_c2d139fc-94a0-42af-acca-ad2eef81cb4f_terseLabel_en-US" xlink:label="lab_slm_LoansOriginatedInCurrentFiscalYear" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Total Private Education Loans, Year 1</link:label>
    <link:label id="lab_slm_LoansOriginatedInCurrentFiscalYear_label_en-US" xlink:label="lab_slm_LoansOriginatedInCurrentFiscalYear" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Loans, Originated In Current Fiscal Year</link:label>
    <link:label id="lab_slm_LoansOriginatedInCurrentFiscalYear_documentation_en-US" xlink:label="lab_slm_LoansOriginatedInCurrentFiscalYear" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Loans, Originated In Current Fiscal Year</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_slm_LoansOriginatedInCurrentFiscalYear" xlink:href="slm-20230331.xsd#slm_LoansOriginatedInCurrentFiscalYear"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_slm_LoansOriginatedInCurrentFiscalYear" xlink:to="lab_slm_LoansOriginatedInCurrentFiscalYear" xlink:type="arc" order="1"/>
    <link:label id="lab_slm_FinancingReceivableCreditLossExpenseReversalCommitments_af3f4aa4-968c-4c60-b048-a6b741ca29fd_totalLabel_en-US" xlink:label="lab_slm_FinancingReceivableCreditLossExpenseReversalCommitments" xlink:role="http://www.xbrl.org/2003/role/totalLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Total Private Education Loan provisions for credit losses</link:label>
    <link:label id="lab_slm_FinancingReceivableCreditLossExpenseReversalCommitments_label_en-US" xlink:label="lab_slm_FinancingReceivableCreditLossExpenseReversalCommitments" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Financing Receivable, Credit Loss, Expense (Reversal), Commitments</link:label>
    <link:label id="lab_slm_FinancingReceivableCreditLossExpenseReversalCommitments_documentation_en-US" xlink:label="lab_slm_FinancingReceivableCreditLossExpenseReversalCommitments" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Financing Receivable, Credit Loss, Expense (Reversal), Commitments</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_slm_FinancingReceivableCreditLossExpenseReversalCommitments" xlink:href="slm-20230331.xsd#slm_FinancingReceivableCreditLossExpenseReversalCommitments"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_slm_FinancingReceivableCreditLossExpenseReversalCommitments" xlink:to="lab_slm_FinancingReceivableCreditLossExpenseReversalCommitments" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_TreasuryStockCommonValue_a9a15233-7364-4b47-8580-7f591b19663c_negatedTerseLabel_en-US" xlink:label="lab_us-gaap_TreasuryStockCommonValue" xlink:role="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Less: Common stock held in treasury at cost: 195.4&#160;million and 194.4&#160;million shares, respectively</link:label>
    <link:label id="lab_us-gaap_TreasuryStockCommonValue_label_en-US" xlink:label="lab_us-gaap_TreasuryStockCommonValue" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Treasury Stock, Common, Value</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_TreasuryStockCommonValue" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_TreasuryStockCommonValue"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_TreasuryStockCommonValue" xlink:to="lab_us-gaap_TreasuryStockCommonValue" xlink:type="arc" order="1"/>
    <link:label id="lab_slm_Maturity2027Member_548c380e-30f5-4028-a655-df0a9260e74e_terseLabel_en-US" xlink:label="lab_slm_Maturity2027Member" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">2027</link:label>
    <link:label id="lab_slm_Maturity2027Member_label_en-US" xlink:label="lab_slm_Maturity2027Member" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Maturity 2027 [Member]</link:label>
    <link:label id="lab_slm_Maturity2027Member_documentation_en-US" xlink:label="lab_slm_Maturity2027Member" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Maturity 2027</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_slm_Maturity2027Member" xlink:href="slm-20230331.xsd#slm_Maturity2027Member"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_slm_Maturity2027Member" xlink:to="lab_slm_Maturity2027Member" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_DilutiveSecuritiesAbstract_16273fda-ed5e-4ba3-9bea-21856321c8f7_terseLabel_en-US" xlink:label="lab_us-gaap_DilutiveSecuritiesAbstract" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Effect of dilutive securities:</link:label>
    <link:label id="lab_us-gaap_DilutiveSecuritiesAbstract_label_en-US" xlink:label="lab_us-gaap_DilutiveSecuritiesAbstract" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Dilutive Securities, Effect on Basic Earnings Per Share [Abstract]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DilutiveSecuritiesAbstract" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_DilutiveSecuritiesAbstract"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_DilutiveSecuritiesAbstract" xlink:to="lab_us-gaap_DilutiveSecuritiesAbstract" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_NoninterestIncomeOtherOperatingIncome_09733217-bd70-4e36-b7e3-3202a63b71ba_terseLabel_en-US" xlink:label="lab_us-gaap_NoninterestIncomeOtherOperatingIncome" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Other income</link:label>
    <link:label id="lab_us-gaap_NoninterestIncomeOtherOperatingIncome_label_en-US" xlink:label="lab_us-gaap_NoninterestIncomeOtherOperatingIncome" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Noninterest Income, Other Operating Income</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NoninterestIncomeOtherOperatingIncome" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_NoninterestIncomeOtherOperatingIncome"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_NoninterestIncomeOtherOperatingIncome" xlink:to="lab_us-gaap_NoninterestIncomeOtherOperatingIncome" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_DerivativeInstrumentRiskAxis_1fa243ae-43b9-4cc2-9b0a-53b1c1dde799_terseLabel_en-US" xlink:label="lab_us-gaap_DerivativeInstrumentRiskAxis" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Derivative Instrument [Axis]</link:label>
    <link:label id="lab_us-gaap_DerivativeInstrumentRiskAxis_label_en-US" xlink:label="lab_us-gaap_DerivativeInstrumentRiskAxis" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Derivative Instrument [Axis]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeInstrumentRiskAxis" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_DerivativeInstrumentRiskAxis"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_DerivativeInstrumentRiskAxis" xlink:to="lab_us-gaap_DerivativeInstrumentRiskAxis" xlink:type="arc" order="1"/>
    <link:label id="lab_slm_FinancingReceivableAllowanceForCreditLossWriteoffAfterRecoveryOriginatedInFiscalYearBeforeLatestFiscalYear_b9a4c9fe-8b4f-456b-95af-7141e41220a3_negatedTerseLabel_en-US" xlink:label="lab_slm_FinancingReceivableAllowanceForCreditLossWriteoffAfterRecoveryOriginatedInFiscalYearBeforeLatestFiscalYear" xlink:role="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Current period net charge-offs, Year 2</link:label>
    <link:label id="lab_slm_FinancingReceivableAllowanceForCreditLossWriteoffAfterRecoveryOriginatedInFiscalYearBeforeLatestFiscalYear_label_en-US" xlink:label="lab_slm_FinancingReceivableAllowanceForCreditLossWriteoffAfterRecoveryOriginatedInFiscalYearBeforeLatestFiscalYear" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Financing Receivable, Allowance for Credit Loss, Writeoff, after Recovery, Originated In Fiscal Year Before Latest Fiscal Year</link:label>
    <link:label id="lab_slm_FinancingReceivableAllowanceForCreditLossWriteoffAfterRecoveryOriginatedInFiscalYearBeforeLatestFiscalYear_documentation_en-US" xlink:label="lab_slm_FinancingReceivableAllowanceForCreditLossWriteoffAfterRecoveryOriginatedInFiscalYearBeforeLatestFiscalYear" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Financing Receivable, Allowance for Credit Loss, Writeoff, after Recovery, Originated In Fiscal Year Before Latest Fiscal Year</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_slm_FinancingReceivableAllowanceForCreditLossWriteoffAfterRecoveryOriginatedInFiscalYearBeforeLatestFiscalYear" xlink:href="slm-20230331.xsd#slm_FinancingReceivableAllowanceForCreditLossWriteoffAfterRecoveryOriginatedInFiscalYearBeforeLatestFiscalYear"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_slm_FinancingReceivableAllowanceForCreditLossWriteoffAfterRecoveryOriginatedInFiscalYearBeforeLatestFiscalYear" xlink:to="lab_slm_FinancingReceivableAllowanceForCreditLossWriteoffAfterRecoveryOriginatedInFiscalYearBeforeLatestFiscalYear" xlink:type="arc" order="1"/>
    <link:label id="lab_slm_ChargeOffsAsPercentageOfAverageLoansInRepayment_c9c627bf-8a15-4054-a9e9-075c9e9c8481_terseLabel_en-US" xlink:label="lab_slm_ChargeOffsAsPercentageOfAverageLoansInRepayment" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Net charge-offs as a percentage of average loans in repayment (annualized)</link:label>
    <link:label id="lab_slm_ChargeOffsAsPercentageOfAverageLoansInRepayment_label_en-US" xlink:label="lab_slm_ChargeOffsAsPercentageOfAverageLoansInRepayment" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Charge Offs As Percentage Of Average Loans In Repayment</link:label>
    <link:label id="lab_slm_ChargeOffsAsPercentageOfAverageLoansInRepayment_documentation_en-US" xlink:label="lab_slm_ChargeOffsAsPercentageOfAverageLoansInRepayment" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Charge offs as percentage of average loans in repayment.</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_slm_ChargeOffsAsPercentageOfAverageLoansInRepayment" xlink:href="slm-20230331.xsd#slm_ChargeOffsAsPercentageOfAverageLoansInRepayment"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_slm_ChargeOffsAsPercentageOfAverageLoansInRepayment" xlink:to="lab_slm_ChargeOffsAsPercentageOfAverageLoansInRepayment" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_VariableInterestEntityNonconsolidatedComparisonOfCarryingAmountOfAssetsAndLiabilitiesToMaximumLossExposureAbstract_c373954f-f82d-4113-84fc-9e56b91f8405_terseLabel_en-US" xlink:label="lab_us-gaap_VariableInterestEntityNonconsolidatedComparisonOfCarryingAmountOfAssetsAndLiabilitiesToMaximumLossExposureAbstract" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Carrying Amount of Assets Securing Debt Outstanding</link:label>
    <link:label id="lab_us-gaap_VariableInterestEntityNonconsolidatedComparisonOfCarryingAmountOfAssetsAndLiabilitiesToMaximumLossExposureAbstract_label_en-US" xlink:label="lab_us-gaap_VariableInterestEntityNonconsolidatedComparisonOfCarryingAmountOfAssetsAndLiabilitiesToMaximumLossExposureAbstract" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Variable Interest Entity, Nonconsolidated, Comparison of Carrying Amount of Assets and Liabilities to Maximum Loss Exposure [Abstract]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_VariableInterestEntityNonconsolidatedComparisonOfCarryingAmountOfAssetsAndLiabilitiesToMaximumLossExposureAbstract" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_VariableInterestEntityNonconsolidatedComparisonOfCarryingAmountOfAssetsAndLiabilitiesToMaximumLossExposureAbstract"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_VariableInterestEntityNonconsolidatedComparisonOfCarryingAmountOfAssetsAndLiabilitiesToMaximumLossExposureAbstract" xlink:to="lab_us-gaap_VariableInterestEntityNonconsolidatedComparisonOfCarryingAmountOfAssetsAndLiabilitiesToMaximumLossExposureAbstract" xlink:type="arc" order="1"/>
    <link:label id="lab_slm_AccruedInterestReceivableOnPrivateEducationLoans_184ac57e-1b72-4ee4-9361-4399cc91e150_terseLabel_en-US" xlink:label="lab_slm_AccruedInterestReceivableOnPrivateEducationLoans" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Total Interest Receivable</link:label>
    <link:label id="lab_slm_AccruedInterestReceivableOnPrivateEducationLoans_label_en-US" xlink:label="lab_slm_AccruedInterestReceivableOnPrivateEducationLoans" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Accrued Interest Receivable On Private Education Loans</link:label>
    <link:label id="lab_slm_AccruedInterestReceivableOnPrivateEducationLoans_documentation_en-US" xlink:label="lab_slm_AccruedInterestReceivableOnPrivateEducationLoans" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Accrued interest receivable on private education loans.</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_slm_AccruedInterestReceivableOnPrivateEducationLoans" xlink:href="slm-20230331.xsd#slm_AccruedInterestReceivableOnPrivateEducationLoans"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_slm_AccruedInterestReceivableOnPrivateEducationLoans" xlink:to="lab_slm_AccruedInterestReceivableOnPrivateEducationLoans" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_StatementOfCashFlowsAbstract_545c9c2f-d42d-4d74-bb2c-760165a6fa38_terseLabel_en-US" xlink:label="lab_us-gaap_StatementOfCashFlowsAbstract" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Statement of Cash Flows [Abstract]</link:label>
    <link:label id="lab_us-gaap_StatementOfCashFlowsAbstract_label_en-US" xlink:label="lab_us-gaap_StatementOfCashFlowsAbstract" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Statement of Cash Flows [Abstract]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementOfCashFlowsAbstract" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_StatementOfCashFlowsAbstract"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_StatementOfCashFlowsAbstract" xlink:to="lab_us-gaap_StatementOfCashFlowsAbstract" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_FairValueInputsLevel1Member_fb2e9038-1002-4112-9805-1db1dc08d512_terseLabel_en-US" xlink:label="lab_us-gaap_FairValueInputsLevel1Member" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Level&#160;1&#160;</link:label>
    <link:label id="lab_us-gaap_FairValueInputsLevel1Member_label_en-US" xlink:label="lab_us-gaap_FairValueInputsLevel1Member" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Fair Value, Inputs, Level 1 [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueInputsLevel1Member" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_FairValueInputsLevel1Member"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_FairValueInputsLevel1Member" xlink:to="lab_us-gaap_FairValueInputsLevel1Member" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_ScheduleOfNotionalAmountsOfOutstandingDerivativePositionsTableTextBlock_4290e4af-e91d-47cf-84bf-674d74abe5bb_terseLabel_en-US" xlink:label="lab_us-gaap_ScheduleOfNotionalAmountsOfOutstandingDerivativePositionsTableTextBlock" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Schedule of Notional Amounts of Outstanding Derivative Positions</link:label>
    <link:label id="lab_us-gaap_ScheduleOfNotionalAmountsOfOutstandingDerivativePositionsTableTextBlock_label_en-US" xlink:label="lab_us-gaap_ScheduleOfNotionalAmountsOfOutstandingDerivativePositionsTableTextBlock" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Schedule of Notional Amounts of Outstanding Derivative Positions [Table Text Block]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfNotionalAmountsOfOutstandingDerivativePositionsTableTextBlock" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ScheduleOfNotionalAmountsOfOutstandingDerivativePositionsTableTextBlock"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_ScheduleOfNotionalAmountsOfOutstandingDerivativePositionsTableTextBlock" xlink:to="lab_us-gaap_ScheduleOfNotionalAmountsOfOutstandingDerivativePositionsTableTextBlock" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_FinancingReceivableExcludingAccruedInterestYearThreeOriginatedTwoYearsBeforeCurrentFiscalYear_6f2a9c5d-4370-4123-abc3-3b0581865606_terseLabel_en-US" xlink:label="lab_us-gaap_FinancingReceivableExcludingAccruedInterestYearThreeOriginatedTwoYearsBeforeCurrentFiscalYear" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Year 3</link:label>
    <link:label id="lab_us-gaap_FinancingReceivableExcludingAccruedInterestYearThreeOriginatedTwoYearsBeforeCurrentFiscalYear_label_en-US" xlink:label="lab_us-gaap_FinancingReceivableExcludingAccruedInterestYearThreeOriginatedTwoYearsBeforeCurrentFiscalYear" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Financing Receivable, Excluding Accrued Interest, Year Three, Originated, Two Years before Current Fiscal Year</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinancingReceivableExcludingAccruedInterestYearThreeOriginatedTwoYearsBeforeCurrentFiscalYear" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_FinancingReceivableExcludingAccruedInterestYearThreeOriginatedTwoYearsBeforeCurrentFiscalYear"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_FinancingReceivableExcludingAccruedInterestYearThreeOriginatedTwoYearsBeforeCurrentFiscalYear" xlink:to="lab_us-gaap_FinancingReceivableExcludingAccruedInterestYearThreeOriginatedTwoYearsBeforeCurrentFiscalYear" xlink:type="arc" order="1"/>
    <link:label id="lab_slm_Maturity2048Member_a80fb4fe-59f7-400d-893f-a9e4dc1e9e53_terseLabel_en-US" xlink:label="lab_slm_Maturity2048Member" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">2048</link:label>
    <link:label id="lab_slm_Maturity2048Member_label_en-US" xlink:label="lab_slm_Maturity2048Member" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Maturity 2048 [Member]</link:label>
    <link:label id="lab_slm_Maturity2048Member_documentation_en-US" xlink:label="lab_slm_Maturity2048Member" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Maturity 2048 [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_slm_Maturity2048Member" xlink:href="slm-20230331.xsd#slm_Maturity2048Member"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_slm_Maturity2048Member" xlink:to="lab_slm_Maturity2048Member" xlink:type="arc" order="1"/>
    <link:label id="lab_slm_Netproceedsfromsalesofstudentloansheldforinvestment_879e1375-6dce-49ac-a88e-2aa8144a39bf_terseLabel_en-US" xlink:label="lab_slm_Netproceedsfromsalesofstudentloansheldforinvestment" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Net proceeds from sales of loans held for investment</link:label>
    <link:label id="lab_slm_Netproceedsfromsalesofstudentloansheldforinvestment_label_en-US" xlink:label="lab_slm_Netproceedsfromsalesofstudentloansheldforinvestment" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Net proceeds from sales of student loans held for investment</link:label>
    <link:label id="lab_slm_Netproceedsfromsalesofstudentloansheldforinvestment_documentation_en-US" xlink:label="lab_slm_Netproceedsfromsalesofstudentloansheldforinvestment" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Net proceeds from sales of student loans held for investment</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_slm_Netproceedsfromsalesofstudentloansheldforinvestment" xlink:href="slm-20230331.xsd#slm_Netproceedsfromsalesofstudentloansheldforinvestment"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_slm_Netproceedsfromsalesofstudentloansheldforinvestment" xlink:to="lab_slm_Netproceedsfromsalesofstudentloansheldforinvestment" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_NetCashProvidedByUsedInOperatingActivities_0fb8282a-0950-4086-b972-327eff8c32b6_totalLabel_en-US" xlink:label="lab_us-gaap_NetCashProvidedByUsedInOperatingActivities" xlink:role="http://www.xbrl.org/2003/role/totalLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Total net cash provided by operating activities</link:label>
    <link:label id="lab_us-gaap_NetCashProvidedByUsedInOperatingActivities_label_en-US" xlink:label="lab_us-gaap_NetCashProvidedByUsedInOperatingActivities" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Net Cash Provided by (Used in) Operating Activities</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_NetCashProvidedByUsedInOperatingActivities"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities" xlink:to="lab_us-gaap_NetCashProvidedByUsedInOperatingActivities" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_TierOneRiskBasedCapital_2f39e944-048c-42b8-9fa2-40bc104c90f4_terseLabel_en-US" xlink:label="lab_us-gaap_TierOneRiskBasedCapital" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Tier 1 Capital (to Risk-Weighted Assets)</link:label>
    <link:label id="lab_us-gaap_TierOneRiskBasedCapital_label_en-US" xlink:label="lab_us-gaap_TierOneRiskBasedCapital" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Banking Regulation, Tier 1 Risk-Based Capital, Actual</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_TierOneRiskBasedCapital" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_TierOneRiskBasedCapital"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_TierOneRiskBasedCapital" xlink:to="lab_us-gaap_TierOneRiskBasedCapital" xlink:type="arc" order="1"/>
    <link:label id="lab_slm_FICOscorelessthan670Member_c7f70815-4e27-4378-824e-0a8d317e7a8e_terseLabel_en-US" xlink:label="lab_slm_FICOscorelessthan670Member" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Less than 670</link:label>
    <link:label id="lab_slm_FICOscorelessthan670Member_label_en-US" xlink:label="lab_slm_FICOscorelessthan670Member" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">FICO score less than 670 [Member]</link:label>
    <link:label id="lab_slm_FICOscorelessthan670Member_documentation_en-US" xlink:label="lab_slm_FICOscorelessthan670Member" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">FICO score less than 670 [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_slm_FICOscorelessthan670Member" xlink:href="slm-20230331.xsd#slm_FICOscorelessthan670Member"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_slm_FICOscorelessthan670Member" xlink:to="lab_slm_FICOscorelessthan670Member" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_DerivativeAssets_917d97a0-72a9-4e4c-aaaa-42e043499bf7_verboseLabel_en-US" xlink:label="lab_us-gaap_DerivativeAssets" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Derivative assets</link:label>
    <link:label id="lab_us-gaap_DerivativeAssets_ed8a7890-90fc-4bd0-a44f-353da0c0f911_totalLabel_en-US" xlink:label="lab_us-gaap_DerivativeAssets" xlink:role="http://www.xbrl.org/2003/role/totalLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Derivative values with impact of master netting agreements (as carried on balance sheet)</link:label>
    <link:label id="lab_us-gaap_DerivativeAssets_c848e2fe-aec0-4132-af4d-6c76789eb5e4_terseLabel_en-US" xlink:label="lab_us-gaap_DerivativeAssets" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Derivative instruments</link:label>
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    <link:label id="lab_us-gaap_NoninterestIncome_8b94b742-cca2-46b5-9134-770e17a9bfb4_totalLabel_en-US" xlink:label="lab_us-gaap_NoninterestIncome" xlink:role="http://www.xbrl.org/2003/role/totalLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Total non-interest income</link:label>
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    <link:label id="lab_us-gaap_FairValueByLiabilityClassAxis_25494463-b64e-450e-9cec-3d6e2d86b9d1_terseLabel_en-US" xlink:label="lab_us-gaap_FairValueByLiabilityClassAxis" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Liability Class [Axis]</link:label>
    <link:label id="lab_us-gaap_FairValueByLiabilityClassAxis_label_en-US" xlink:label="lab_us-gaap_FairValueByLiabilityClassAxis" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Liability Class [Axis]</link:label>
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    <link:label id="lab_slm_AccruedInterestToBeCapitalizedOnLoansInRepayment_88a0e068-f9a1-43a7-acf3-0c0bd7940b59_terseLabel_en-US" xlink:label="lab_slm_AccruedInterestToBeCapitalizedOnLoansInRepayment" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Accrued interest to be capitalized on loans in repayment</link:label>
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    <link:label id="lab_us-gaap_LoansNotesTradeAndOtherReceivablesDisclosureTextBlock_e5ed3e11-bcd5-4d42-80a1-67ef9d30d667_terseLabel_en-US" xlink:label="lab_us-gaap_LoansNotesTradeAndOtherReceivablesDisclosureTextBlock" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Loans Held for Investment</link:label>
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    <link:label id="lab_us-gaap_CertificatesOfDepositMember_6cb195f8-def9-4af8-9815-29dc72078b8c_terseLabel_en-US" xlink:label="lab_us-gaap_CertificatesOfDepositMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Certificates of deposit</link:label>
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    <link:label id="lab_slm_FinancingReceivableAfterAllowanceForCreditLossOriginatedInCurrentFiscalYear_3a3a1014-e502-4e24-99c8-14124f8b9e24_terseLabel_en-US" xlink:label="lab_slm_FinancingReceivableAfterAllowanceForCreditLossOriginatedInCurrentFiscalYear" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Private Education Loans, net, Year 1</link:label>
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    <link:label id="lab_us-gaap_OtherComprehensiveIncomeLossCashFlowHedgeGainLossReclassificationBeforeTax_07ba4a73-e1f5-4318-8df5-f84625178117_terseLabel_en-US" xlink:label="lab_us-gaap_OtherComprehensiveIncomeLossCashFlowHedgeGainLossReclassificationBeforeTax" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Less: amount of gain (loss) reclassified in interest expense</link:label>
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    <link:label id="lab_us-gaap_VariableIncomeInterestRateMember_39de09fa-1241-4d47-a3a5-747fe8bc6bae_terseLabel_en-US" xlink:label="lab_us-gaap_VariableIncomeInterestRateMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Variable-rate</link:label>
    <link:label id="lab_us-gaap_VariableIncomeInterestRateMember_label_en-US" xlink:label="lab_us-gaap_VariableIncomeInterestRateMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Variable Income Interest Rate [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_VariableIncomeInterestRateMember" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_VariableIncomeInterestRateMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_VariableIncomeInterestRateMember" xlink:to="lab_us-gaap_VariableIncomeInterestRateMember" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_CreditScoreFicoDomain_872d4ca1-7831-4459-9f76-9e158bede93e_terseLabel_en-US" xlink:label="lab_us-gaap_CreditScoreFicoDomain" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Credit Score, FICO [Domain]</link:label>
    <link:label id="lab_us-gaap_CreditScoreFicoDomain_label_en-US" xlink:label="lab_us-gaap_CreditScoreFicoDomain" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Credit Score, FICO [Domain]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CreditScoreFicoDomain" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_CreditScoreFicoDomain"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_CreditScoreFicoDomain" xlink:to="lab_us-gaap_CreditScoreFicoDomain" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_StockIssuedDuringPeriodValueNewIssues_9553a12e-3058-4d58-a991-f39068f734c9_terseLabel_en-US" xlink:label="lab_us-gaap_StockIssuedDuringPeriodValueNewIssues" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Issuance of common shares</link:label>
    <link:label id="lab_us-gaap_StockIssuedDuringPeriodValueNewIssues_label_en-US" xlink:label="lab_us-gaap_StockIssuedDuringPeriodValueNewIssues" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Stock Issued During Period, Value, New Issues</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockIssuedDuringPeriodValueNewIssues" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_StockIssuedDuringPeriodValueNewIssues"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_StockIssuedDuringPeriodValueNewIssues" xlink:to="lab_us-gaap_StockIssuedDuringPeriodValueNewIssues" xlink:type="arc" order="1"/>
    <link:label id="lab_slm_VerticalRiskRetentionPercentage_3b7fbfcb-767f-4f53-839f-5f0ea7e7becb_terseLabel_en-US" xlink:label="lab_slm_VerticalRiskRetentionPercentage" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Vertical risk retention interest</link:label>
    <link:label id="lab_slm_VerticalRiskRetentionPercentage_label_en-US" xlink:label="lab_slm_VerticalRiskRetentionPercentage" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Vertical Risk Retention, Percentage</link:label>
    <link:label id="lab_slm_VerticalRiskRetentionPercentage_documentation_en-US" xlink:label="lab_slm_VerticalRiskRetentionPercentage" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Vertical Risk Retention, Percentage</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_slm_VerticalRiskRetentionPercentage" xlink:href="slm-20230331.xsd#slm_VerticalRiskRetentionPercentage"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_slm_VerticalRiskRetentionPercentage" xlink:to="lab_slm_VerticalRiskRetentionPercentage" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_DividendsPreferredStockCash_0932ceee-091b-4458-a2af-ed5dbfcfa820_negatedTerseLabel_en-US" xlink:label="lab_us-gaap_DividendsPreferredStockCash" xlink:role="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Preferred Stock</link:label>
    <link:label id="lab_us-gaap_DividendsPreferredStockCash_label_en-US" xlink:label="lab_us-gaap_DividendsPreferredStockCash" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Dividends, Preferred Stock, Cash</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DividendsPreferredStockCash" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_DividendsPreferredStockCash"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_DividendsPreferredStockCash" xlink:to="lab_us-gaap_DividendsPreferredStockCash" xlink:type="arc" order="1"/>
    <link:label id="lab_slm_SeasoningBasedOnMonthlyScheduledPaymentsDueFromTwentyFiveToThirtySixPaymentsInPercent_a3894146-b5cf-4a91-8ee5-ab46f92cf100_terseLabel_en-US" xlink:label="lab_slm_SeasoningBasedOnMonthlyScheduledPaymentsDueFromTwentyFiveToThirtySixPaymentsInPercent" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Seasoning based on monthly scheduled payments due from 25 - 36 payments</link:label>
    <link:label id="lab_slm_SeasoningBasedOnMonthlyScheduledPaymentsDueFromTwentyFiveToThirtySixPaymentsInPercent_label_en-US" xlink:label="lab_slm_SeasoningBasedOnMonthlyScheduledPaymentsDueFromTwentyFiveToThirtySixPaymentsInPercent" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Seasoning Based On Monthly Scheduled Payments Due From Twenty Five To Thirty Six Payments In Percent</link:label>
    <link:label id="lab_slm_SeasoningBasedOnMonthlyScheduledPaymentsDueFromTwentyFiveToThirtySixPaymentsInPercent_documentation_en-US" xlink:label="lab_slm_SeasoningBasedOnMonthlyScheduledPaymentsDueFromTwentyFiveToThirtySixPaymentsInPercent" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Seasoning based on monthly scheduled payments due from thirteen to twenty four payments in percent</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_slm_SeasoningBasedOnMonthlyScheduledPaymentsDueFromTwentyFiveToThirtySixPaymentsInPercent" xlink:href="slm-20230331.xsd#slm_SeasoningBasedOnMonthlyScheduledPaymentsDueFromTwentyFiveToThirtySixPaymentsInPercent"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_slm_SeasoningBasedOnMonthlyScheduledPaymentsDueFromTwentyFiveToThirtySixPaymentsInPercent" xlink:to="lab_slm_SeasoningBasedOnMonthlyScheduledPaymentsDueFromTwentyFiveToThirtySixPaymentsInPercent" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_FinancingReceivablesPeriodPastDueAxis_676116bd-8375-41e8-bd95-fef8d4be0697_terseLabel_en-US" xlink:label="lab_us-gaap_FinancingReceivablesPeriodPastDueAxis" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Financial Asset, Period Past Due [Axis]</link:label>
    <link:label id="lab_us-gaap_FinancingReceivablesPeriodPastDueAxis_label_en-US" xlink:label="lab_us-gaap_FinancingReceivablesPeriodPastDueAxis" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Financial Asset, Aging [Axis]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinancingReceivablesPeriodPastDueAxis" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_FinancingReceivablesPeriodPastDueAxis"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_FinancingReceivablesPeriodPastDueAxis" xlink:to="lab_us-gaap_FinancingReceivablesPeriodPastDueAxis" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_DebtDisclosureTextBlock_918761b2-998c-4183-81a6-019c91def77f_terseLabel_en-US" xlink:label="lab_us-gaap_DebtDisclosureTextBlock" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Borrowings</link:label>
    <link:label id="lab_us-gaap_DebtDisclosureTextBlock_label_en-US" xlink:label="lab_us-gaap_DebtDisclosureTextBlock" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Debt Disclosure [Text Block]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtDisclosureTextBlock" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_DebtDisclosureTextBlock"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_DebtDisclosureTextBlock" xlink:to="lab_us-gaap_DebtDisclosureTextBlock" xlink:type="arc" order="1"/>
    <link:label id="lab_slm_DelinquenciesAsPercentageOfLoansInRepaymentOriginatedInFiscalYearBeforeLatestFiscalYear_59392a27-af30-49de-a4a1-b332b000d772_terseLabel_en-US" xlink:label="lab_slm_DelinquenciesAsPercentageOfLoansInRepaymentOriginatedInFiscalYearBeforeLatestFiscalYear" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Delinquent Private Education Loans in repayment as a percentage of Private Education Loans in repayment, Year 2</link:label>
    <link:label id="lab_slm_DelinquenciesAsPercentageOfLoansInRepaymentOriginatedInFiscalYearBeforeLatestFiscalYear_label_en-US" xlink:label="lab_slm_DelinquenciesAsPercentageOfLoansInRepaymentOriginatedInFiscalYearBeforeLatestFiscalYear" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Delinquencies As Percentage Of Loans In Repayment, Originated In Fiscal Year Before Latest Fiscal Year</link:label>
    <link:label id="lab_slm_DelinquenciesAsPercentageOfLoansInRepaymentOriginatedInFiscalYearBeforeLatestFiscalYear_documentation_en-US" xlink:label="lab_slm_DelinquenciesAsPercentageOfLoansInRepaymentOriginatedInFiscalYearBeforeLatestFiscalYear" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Delinquencies As Percentage Of Loans In Repayment, Originated In Fiscal Year Before Latest Fiscal Year</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_slm_DelinquenciesAsPercentageOfLoansInRepaymentOriginatedInFiscalYearBeforeLatestFiscalYear" xlink:href="slm-20230331.xsd#slm_DelinquenciesAsPercentageOfLoansInRepaymentOriginatedInFiscalYearBeforeLatestFiscalYear"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_slm_DelinquenciesAsPercentageOfLoansInRepaymentOriginatedInFiscalYearBeforeLatestFiscalYear" xlink:to="lab_slm_DelinquenciesAsPercentageOfLoansInRepaymentOriginatedInFiscalYearBeforeLatestFiscalYear" xlink:type="arc" order="1"/>
    <link:label id="lab_dei_EntityShellCompany_565aadde-3294-4e8b-86bb-9894e9eb3be2_terseLabel_en-US" xlink:label="lab_dei_EntityShellCompany" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Entity Shell Company</link:label>
    <link:label id="lab_dei_EntityShellCompany_label_en-US" xlink:label="lab_dei_EntityShellCompany" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Entity Shell Company</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityShellCompany" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_EntityShellCompany"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_dei_EntityShellCompany" xlink:to="lab_dei_EntityShellCompany" xlink:type="arc" order="1"/>
    <link:label id="lab_slm_LoansOriginatedFiveOrMoreYearsBeforeLatestFiscalYear_a70ef146-5506-4c4f-8e78-08b59b160ab6_terseLabel_en-US" xlink:label="lab_slm_LoansOriginatedFiveOrMoreYearsBeforeLatestFiscalYear" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Total Private Education Loans, After Year 5</link:label>
    <link:label id="lab_slm_LoansOriginatedFiveOrMoreYearsBeforeLatestFiscalYear_label_en-US" xlink:label="lab_slm_LoansOriginatedFiveOrMoreYearsBeforeLatestFiscalYear" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Loans, Originated Five Or More Years Before Latest Fiscal Year</link:label>
    <link:label id="lab_slm_LoansOriginatedFiveOrMoreYearsBeforeLatestFiscalYear_documentation_en-US" xlink:label="lab_slm_LoansOriginatedFiveOrMoreYearsBeforeLatestFiscalYear" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Loans, Originated Five Or More Years Before Latest Fiscal Year</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_slm_LoansOriginatedFiveOrMoreYearsBeforeLatestFiscalYear" xlink:href="slm-20230331.xsd#slm_LoansOriginatedFiveOrMoreYearsBeforeLatestFiscalYear"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_slm_LoansOriginatedFiveOrMoreYearsBeforeLatestFiscalYear" xlink:to="lab_slm_LoansOriginatedFiveOrMoreYearsBeforeLatestFiscalYear" xlink:type="arc" order="1"/>
    <link:label id="lab_slm_FinancingReceivableAllowanceForCreditLossWriteoffAfterRecoveryOriginatedTwoYearsBeforeCurrentFiscalYear_5081c92d-8543-4d7a-abc1-638d93e1a3fd_negatedTerseLabel_en-US" xlink:label="lab_slm_FinancingReceivableAllowanceForCreditLossWriteoffAfterRecoveryOriginatedTwoYearsBeforeCurrentFiscalYear" xlink:role="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Current period recoveries, Year 3</link:label>
    <link:label id="lab_slm_FinancingReceivableAllowanceForCreditLossWriteoffAfterRecoveryOriginatedTwoYearsBeforeCurrentFiscalYear_label_en-US" xlink:label="lab_slm_FinancingReceivableAllowanceForCreditLossWriteoffAfterRecoveryOriginatedTwoYearsBeforeCurrentFiscalYear" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Financing Receivable, Allowance for Credit Loss, Writeoff, after Recovery, Originated Two Years Before Current Fiscal Year</link:label>
    <link:label id="lab_slm_FinancingReceivableAllowanceForCreditLossWriteoffAfterRecoveryOriginatedTwoYearsBeforeCurrentFiscalYear_documentation_en-US" xlink:label="lab_slm_FinancingReceivableAllowanceForCreditLossWriteoffAfterRecoveryOriginatedTwoYearsBeforeCurrentFiscalYear" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Financing Receivable, Allowance for Credit Loss, Writeoff, after Recovery, Originated Two Years Before Current Fiscal Year</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_slm_FinancingReceivableAllowanceForCreditLossWriteoffAfterRecoveryOriginatedTwoYearsBeforeCurrentFiscalYear" xlink:href="slm-20230331.xsd#slm_FinancingReceivableAllowanceForCreditLossWriteoffAfterRecoveryOriginatedTwoYearsBeforeCurrentFiscalYear"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_slm_FinancingReceivableAllowanceForCreditLossWriteoffAfterRecoveryOriginatedTwoYearsBeforeCurrentFiscalYear" xlink:to="lab_slm_FinancingReceivableAllowanceForCreditLossWriteoffAfterRecoveryOriginatedTwoYearsBeforeCurrentFiscalYear" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_IncreaseDecreaseInOperatingAssetsAbstract_4400deb6-c462-4743-9080-27c3a3f5819d_terseLabel_en-US" xlink:label="lab_us-gaap_IncreaseDecreaseInOperatingAssetsAbstract" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Changes in operating assets and liabilities:</link:label>
    <link:label id="lab_us-gaap_IncreaseDecreaseInOperatingAssetsAbstract_label_en-US" xlink:label="lab_us-gaap_IncreaseDecreaseInOperatingAssetsAbstract" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Increase (Decrease) in Operating Assets [Abstract]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInOperatingAssetsAbstract" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_IncreaseDecreaseInOperatingAssetsAbstract"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_IncreaseDecreaseInOperatingAssetsAbstract" xlink:to="lab_us-gaap_IncreaseDecreaseInOperatingAssetsAbstract" xlink:type="arc" order="1"/>
    <link:label id="lab_slm_DerivativeCashCollateralHeldRelativetoDerivativeExposureNet_f35e06be-5dfc-429c-a841-b0fcea013f96_terseLabel_en-US" xlink:label="lab_slm_DerivativeCashCollateralHeldRelativetoDerivativeExposureNet" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Cash collateral held relative to derivative exposure</link:label>
    <link:label id="lab_slm_DerivativeCashCollateralHeldRelativetoDerivativeExposureNet_label_en-US" xlink:label="lab_slm_DerivativeCashCollateralHeldRelativetoDerivativeExposureNet" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Derivative, Cash Collateral Held Relative to Derivative Exposure, Net</link:label>
    <link:label id="lab_slm_DerivativeCashCollateralHeldRelativetoDerivativeExposureNet_documentation_en-US" xlink:label="lab_slm_DerivativeCashCollateralHeldRelativetoDerivativeExposureNet" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Derivative, Cash Collateral Held Relative to Derivative Exposure, Net</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_slm_DerivativeCashCollateralHeldRelativetoDerivativeExposureNet" xlink:href="slm-20230331.xsd#slm_DerivativeCashCollateralHeldRelativetoDerivativeExposureNet"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_slm_DerivativeCashCollateralHeldRelativetoDerivativeExposureNet" xlink:to="lab_slm_DerivativeCashCollateralHeldRelativetoDerivativeExposureNet" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_FinancialInstrumentAxis_35508a38-ee28-4be5-8cd6-63d46456b875_terseLabel_en-US" xlink:label="lab_us-gaap_FinancialInstrumentAxis" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Financial Instrument [Axis]</link:label>
    <link:label id="lab_us-gaap_FinancialInstrumentAxis_label_en-US" xlink:label="lab_us-gaap_FinancialInstrumentAxis" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Financial Instrument [Axis]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinancialInstrumentAxis" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_FinancialInstrumentAxis"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_FinancialInstrumentAxis" xlink:to="lab_us-gaap_FinancialInstrumentAxis" xlink:type="arc" order="1"/>
    <link:label id="lab_slm_ThresholdPeriodPastDueForWriteOffOfFinancingReceivable_634d53c3-7aa0-42ca-a92b-b7adbb3ebb3f_terseLabel_en-US" xlink:label="lab_slm_ThresholdPeriodPastDueForWriteOffOfFinancingReceivable" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Threshold period when delinquent loans are written off</link:label>
    <link:label id="lab_slm_ThresholdPeriodPastDueForWriteOffOfFinancingReceivable_label_en-US" xlink:label="lab_slm_ThresholdPeriodPastDueForWriteOffOfFinancingReceivable" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Threshold Period Past Due For Write-off Of Financing Receivable</link:label>
    <link:label id="lab_slm_ThresholdPeriodPastDueForWriteOffOfFinancingReceivable_documentation_en-US" xlink:label="lab_slm_ThresholdPeriodPastDueForWriteOffOfFinancingReceivable" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Threshold Period Past Due For Write-off Of Financing Receivable</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_slm_ThresholdPeriodPastDueForWriteOffOfFinancingReceivable" xlink:href="slm-20230331.xsd#slm_ThresholdPeriodPastDueForWriteOffOfFinancingReceivable"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_slm_ThresholdPeriodPastDueForWriteOffOfFinancingReceivable" xlink:to="lab_slm_ThresholdPeriodPastDueForWriteOffOfFinancingReceivable" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_OtherInvestments_d0da57cd-d862-4188-acdf-f467ccaac717_terseLabel_en-US" xlink:label="lab_us-gaap_OtherInvestments" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Other investments</link:label>
    <link:label id="lab_us-gaap_OtherInvestments_label_en-US" xlink:label="lab_us-gaap_OtherInvestments" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Other Investments</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherInvestments" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_OtherInvestments"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_OtherInvestments" xlink:to="lab_us-gaap_OtherInvestments" xlink:type="arc" order="1"/>
    <link:label id="lab_slm_FinancialAssetEqualToOrGreaterThan60DaysPastDueMember_9179559e-8b5b-4ad3-9a68-66f7ab87e1bc_terseLabel_en-US" xlink:label="lab_slm_FinancialAssetEqualToOrGreaterThan60DaysPastDueMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">60 Days or Greater Past Due</link:label>
    <link:label id="lab_slm_FinancialAssetEqualToOrGreaterThan60DaysPastDueMember_label_en-US" xlink:label="lab_slm_FinancialAssetEqualToOrGreaterThan60DaysPastDueMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Financial Asset, Equal To Or Greater Than 60 Days Past Due [Member]</link:label>
    <link:label id="lab_slm_FinancialAssetEqualToOrGreaterThan60DaysPastDueMember_documentation_en-US" xlink:label="lab_slm_FinancialAssetEqualToOrGreaterThan60DaysPastDueMember" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Financial Asset, Equal To Or Greater Than 60 Days Past Due</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_slm_FinancialAssetEqualToOrGreaterThan60DaysPastDueMember" xlink:href="slm-20230331.xsd#slm_FinancialAssetEqualToOrGreaterThan60DaysPastDueMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_slm_FinancialAssetEqualToOrGreaterThan60DaysPastDueMember" xlink:to="lab_slm_FinancialAssetEqualToOrGreaterThan60DaysPastDueMember" xlink:type="arc" order="1"/>
    <link:label id="lab_slm_AllowanceCoverageOfChargeOffsAverageLoansInRepayment_02d09c32-8ad4-4dd3-a5a5-f2bc98b16665_terseLabel_en-US" xlink:label="lab_slm_AllowanceCoverageOfChargeOffsAverageLoansInRepayment" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Average loans in repayment</link:label>
    <link:label id="lab_slm_AllowanceCoverageOfChargeOffsAverageLoansInRepayment_label_en-US" xlink:label="lab_slm_AllowanceCoverageOfChargeOffsAverageLoansInRepayment" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Allowance Coverage Of Charge Offs Average Loans In Repayment</link:label>
    <link:label id="lab_slm_AllowanceCoverageOfChargeOffsAverageLoansInRepayment_documentation_en-US" xlink:label="lab_slm_AllowanceCoverageOfChargeOffsAverageLoansInRepayment" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Allowance coverage of charge offs average loans in repayment.</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_slm_AllowanceCoverageOfChargeOffsAverageLoansInRepayment" xlink:href="slm-20230331.xsd#slm_AllowanceCoverageOfChargeOffsAverageLoansInRepayment"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_slm_AllowanceCoverageOfChargeOffsAverageLoansInRepayment" xlink:to="lab_slm_AllowanceCoverageOfChargeOffsAverageLoansInRepayment" xlink:type="arc" order="1"/>
    <link:label id="lab_dei_DocumentPeriodEndDate_43e39e1a-4361-4b23-8123-312b861bff87_terseLabel_en-US" xlink:label="lab_dei_DocumentPeriodEndDate" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Document Period End Date</link:label>
    <link:label id="lab_dei_DocumentPeriodEndDate_label_en-US" xlink:label="lab_dei_DocumentPeriodEndDate" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Document Period End Date</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_dei_DocumentPeriodEndDate" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_DocumentPeriodEndDate"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_dei_DocumentPeriodEndDate" xlink:to="lab_dei_DocumentPeriodEndDate" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_TimeDepositMaturitiesRollingYearFour_4ee9f7e4-b517-4ab1-b17e-4211c7c26566_terseLabel_en-US" xlink:label="lab_us-gaap_TimeDepositMaturitiesRollingYearFour" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">After three years to four years</link:label>
    <link:label id="lab_us-gaap_TimeDepositMaturitiesRollingYearFour_label_en-US" xlink:label="lab_us-gaap_TimeDepositMaturitiesRollingYearFour" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Time Deposit Maturities, Rolling Year Four</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_TimeDepositMaturitiesRollingYearFour" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_TimeDepositMaturitiesRollingYearFour"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_TimeDepositMaturitiesRollingYearFour" xlink:to="lab_us-gaap_TimeDepositMaturitiesRollingYearFour" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_ScheduleOfAccumulatedOtherComprehensiveIncomeLossTableTextBlock_6ff723af-603b-4a47-a95e-9be5a82f5360_terseLabel_en-US" xlink:label="lab_us-gaap_ScheduleOfAccumulatedOtherComprehensiveIncomeLossTableTextBlock" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Schedule of Derivative Instruments, Effect on Other Comprehensive Income (Loss)</link:label>
    <link:label id="lab_us-gaap_ScheduleOfAccumulatedOtherComprehensiveIncomeLossTableTextBlock_label_en-US" xlink:label="lab_us-gaap_ScheduleOfAccumulatedOtherComprehensiveIncomeLossTableTextBlock" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Schedule of Accumulated Other Comprehensive Income (Loss) [Table Text Block]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfAccumulatedOtherComprehensiveIncomeLossTableTextBlock" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ScheduleOfAccumulatedOtherComprehensiveIncomeLossTableTextBlock"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_ScheduleOfAccumulatedOtherComprehensiveIncomeLossTableTextBlock" xlink:to="lab_us-gaap_ScheduleOfAccumulatedOtherComprehensiveIncomeLossTableTextBlock" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_Assets_ac3525af-96b8-40f4-83d1-2361969705d2_totalLabel_en-US" xlink:label="lab_us-gaap_Assets" xlink:role="http://www.xbrl.org/2003/role/totalLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Total assets</link:label>
    <link:label id="lab_us-gaap_Assets_label_en-US" xlink:label="lab_us-gaap_Assets" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Assets</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_Assets" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_Assets"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_Assets" xlink:to="lab_us-gaap_Assets" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_EarningsPerShareAbstract_2c7a9e40-414c-4c1d-95d3-36849a125d74_terseLabel_en-US" xlink:label="lab_us-gaap_EarningsPerShareAbstract" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Earnings Per Share [Abstract]</link:label>
    <link:label id="lab_us-gaap_EarningsPerShareAbstract_label_en-US" xlink:label="lab_us-gaap_EarningsPerShareAbstract" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Earnings Per Share [Abstract]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EarningsPerShareAbstract" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_EarningsPerShareAbstract"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_EarningsPerShareAbstract" xlink:to="lab_us-gaap_EarningsPerShareAbstract" xlink:type="arc" order="1"/>
    <link:label id="lab_slm_Maturity2052Member_8df923d8-29d5-4be4-8c59-9577e27e7ef2_terseLabel_en-US" xlink:label="lab_slm_Maturity2052Member" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">2052</link:label>
    <link:label id="lab_slm_Maturity2052Member_label_en-US" xlink:label="lab_slm_Maturity2052Member" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Maturity 2052 [Member]</link:label>
    <link:label id="lab_slm_Maturity2052Member_documentation_en-US" xlink:label="lab_slm_Maturity2052Member" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Maturity 2052</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_slm_Maturity2052Member" xlink:href="slm-20230331.xsd#slm_Maturity2052Member"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_slm_Maturity2052Member" xlink:to="lab_slm_Maturity2052Member" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_AccountsNotesLoansAndFinancingReceivablesByIndustryOfCounterpartyTypeAxis_0d3cdb64-e9bd-48dd-8ca3-c3cc29194182_terseLabel_en-US" xlink:label="lab_us-gaap_AccountsNotesLoansAndFinancingReceivablesByIndustryOfCounterpartyTypeAxis" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Industry of Counterparty, Type [Axis]</link:label>
    <link:label id="lab_us-gaap_AccountsNotesLoansAndFinancingReceivablesByIndustryOfCounterpartyTypeAxis_label_en-US" xlink:label="lab_us-gaap_AccountsNotesLoansAndFinancingReceivablesByIndustryOfCounterpartyTypeAxis" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Industry of Counterparty, Type [Axis]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccountsNotesLoansAndFinancingReceivablesByIndustryOfCounterpartyTypeAxis" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AccountsNotesLoansAndFinancingReceivablesByIndustryOfCounterpartyTypeAxis"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_AccountsNotesLoansAndFinancingReceivablesByIndustryOfCounterpartyTypeAxis" xlink:to="lab_us-gaap_AccountsNotesLoansAndFinancingReceivablesByIndustryOfCounterpartyTypeAxis" xlink:type="arc" order="1"/>
    <link:label id="lab_slm_CreditCardsMember_270169d4-c9fb-4231-bdb9-3f1f87751626_terseLabel_en-US" xlink:label="lab_slm_CreditCardsMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Credit Cards</link:label>
    <link:label id="lab_slm_CreditCardsMember_label_en-US" xlink:label="lab_slm_CreditCardsMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Credit Cards [Member]</link:label>
    <link:label id="lab_slm_CreditCardsMember_documentation_en-US" xlink:label="lab_slm_CreditCardsMember" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Credit Cards</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_slm_CreditCardsMember" xlink:href="slm-20230331.xsd#slm_CreditCardsMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_slm_CreditCardsMember" xlink:to="lab_slm_CreditCardsMember" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_InterestRateSwapMember_195f9851-b5c1-4d01-88a1-732030a79ee4_verboseLabel_en-US" xlink:label="lab_us-gaap_InterestRateSwapMember" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Interest rate swaps</link:label>
    <link:label id="lab_us-gaap_InterestRateSwapMember_d276ad9d-751d-4b04-a678-04bbe283b0c1_terseLabel_en-US" xlink:label="lab_us-gaap_InterestRateSwapMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Interest rate swaps</link:label>
    <link:label id="lab_us-gaap_InterestRateSwapMember_label_en-US" xlink:label="lab_us-gaap_InterestRateSwapMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Interest Rate Swap [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestRateSwapMember" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_InterestRateSwapMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_InterestRateSwapMember" xlink:to="lab_us-gaap_InterestRateSwapMember" xlink:type="arc" order="1"/>
    <link:label id="lab_slm_AnnualizedAllowanceOnPrivateEducationLoanCoverageOfChargeOffs_0a4a2dac-6420-49b0-a2a2-d614331cb590_terseLabel_en-US" xlink:label="lab_slm_AnnualizedAllowanceOnPrivateEducationLoanCoverageOfChargeOffs" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Allowance coverage of net charge-offs (annualized)</link:label>
    <link:label id="lab_slm_AnnualizedAllowanceOnPrivateEducationLoanCoverageOfChargeOffs_label_en-US" xlink:label="lab_slm_AnnualizedAllowanceOnPrivateEducationLoanCoverageOfChargeOffs" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Annualized Allowance On Private Education Loan Coverage Of Charge Offs</link:label>
    <link:label id="lab_slm_AnnualizedAllowanceOnPrivateEducationLoanCoverageOfChargeOffs_documentation_en-US" xlink:label="lab_slm_AnnualizedAllowanceOnPrivateEducationLoanCoverageOfChargeOffs" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Annualized allowance on private education loan coverage of charge offs.</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_slm_AnnualizedAllowanceOnPrivateEducationLoanCoverageOfChargeOffs" xlink:href="slm-20230331.xsd#slm_AnnualizedAllowanceOnPrivateEducationLoanCoverageOfChargeOffs"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_slm_AnnualizedAllowanceOnPrivateEducationLoanCoverageOfChargeOffs" xlink:to="lab_slm_AnnualizedAllowanceOnPrivateEducationLoanCoverageOfChargeOffs" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_SharesIssued_dbd7770c-5d61-4197-869e-19c1e5d7cb05_periodStartLabel_en-US" xlink:label="lab_us-gaap_SharesIssued" xlink:role="http://www.xbrl.org/2003/role/periodStartLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Beginning balance, shares issued (in shares)</link:label>
    <link:label id="lab_us-gaap_SharesIssued_5027183c-546e-4f27-bdfc-0a43ec6bb116_periodEndLabel_en-US" xlink:label="lab_us-gaap_SharesIssued" xlink:role="http://www.xbrl.org/2003/role/periodEndLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Ending balance, shares issued (in shares)</link:label>
    <link:label id="lab_us-gaap_SharesIssued_label_en-US" xlink:label="lab_us-gaap_SharesIssued" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Shares, Issued</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SharesIssued" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_SharesIssued"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_SharesIssued" xlink:to="lab_us-gaap_SharesIssued" xlink:type="arc" order="1"/>
    <link:label id="lab_slm_TaxIndemnificationReceivable_551301ef-cb84-4b73-bcfa-b18ee4953dd5_terseLabel_en-US" xlink:label="lab_slm_TaxIndemnificationReceivable" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Tax indemnification receivable</link:label>
    <link:label id="lab_slm_TaxIndemnificationReceivable_label_en-US" xlink:label="lab_slm_TaxIndemnificationReceivable" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Tax Indemnification Receivable</link:label>
    <link:label id="lab_slm_TaxIndemnificationReceivable_documentation_en-US" xlink:label="lab_slm_TaxIndemnificationReceivable" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Tax Indemnification Receivable</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_slm_TaxIndemnificationReceivable" xlink:href="slm-20230331.xsd#slm_TaxIndemnificationReceivable"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_slm_TaxIndemnificationReceivable" xlink:to="lab_slm_TaxIndemnificationReceivable" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_PreferredStockLiquidationPreference_de0aa99e-55ab-4c7f-9d01-6a5de3d966b3_terseLabel_en-US" xlink:label="lab_us-gaap_PreferredStockLiquidationPreference" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Preferred stock, liquidation preference (in dollars per share)</link:label>
    <link:label id="lab_us-gaap_PreferredStockLiquidationPreference_label_en-US" xlink:label="lab_us-gaap_PreferredStockLiquidationPreference" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Preferred Stock, Liquidation Preference Per Share</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PreferredStockLiquidationPreference" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_PreferredStockLiquidationPreference"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_PreferredStockLiquidationPreference" xlink:to="lab_us-gaap_PreferredStockLiquidationPreference" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_LongTermDebtFairValue_22868ffe-cccf-482e-a4ec-0df4d0e563f3_terseLabel_en-US" xlink:label="lab_us-gaap_LongTermDebtFairValue" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Long-term borrowings</link:label>
    <link:label id="lab_us-gaap_LongTermDebtFairValue_label_en-US" xlink:label="lab_us-gaap_LongTermDebtFairValue" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Long-Term Debt, Fair Value</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongTermDebtFairValue" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_LongTermDebtFairValue"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_LongTermDebtFairValue" xlink:to="lab_us-gaap_LongTermDebtFairValue" xlink:type="arc" order="1"/>
    <link:label id="lab_slm_FinancingReceivableChangeInContractualRate_445f8d9f-2184-43e1-9896-fd03d5d02e16_terseLabel_en-US" xlink:label="lab_slm_FinancingReceivableChangeInContractualRate" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Average contractual rate</link:label>
    <link:label id="lab_slm_FinancingReceivableChangeInContractualRate_label_en-US" xlink:label="lab_slm_FinancingReceivableChangeInContractualRate" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Financing Receivable, Change in Contractual Rate</link:label>
    <link:label id="lab_slm_FinancingReceivableChangeInContractualRate_documentation_en-US" xlink:label="lab_slm_FinancingReceivableChangeInContractualRate" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Financing Receivable, Change in Contractual Rate</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_slm_FinancingReceivableChangeInContractualRate" xlink:href="slm-20230331.xsd#slm_FinancingReceivableChangeInContractualRate"/>
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    <link:label id="lab_us-gaap_StockRepurchaseProgramAuthorizedAmount1_f7527a26-35e8-4298-96cf-4599912fbe92_terseLabel_en-US" xlink:label="lab_us-gaap_StockRepurchaseProgramAuthorizedAmount1" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Aggregate purchase price (not to exceed)</link:label>
    <link:label id="lab_us-gaap_StockRepurchaseProgramAuthorizedAmount1_label_en-US" xlink:label="lab_us-gaap_StockRepurchaseProgramAuthorizedAmount1" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Stock Repurchase Program, Authorized Amount</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockRepurchaseProgramAuthorizedAmount1" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_StockRepurchaseProgramAuthorizedAmount1"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_StockRepurchaseProgramAuthorizedAmount1" xlink:to="lab_us-gaap_StockRepurchaseProgramAuthorizedAmount1" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_NotesReceivableGross_8eafa46e-49fa-43d5-9fcd-0a3f4892baa6_verboseLabel_en-US" xlink:label="lab_us-gaap_NotesReceivableGross" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Loans</link:label>
    <link:label id="lab_us-gaap_NotesReceivableGross_label_en-US" xlink:label="lab_us-gaap_NotesReceivableGross" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Financing Receivable, before Allowance for Credit Loss</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NotesReceivableGross" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_NotesReceivableGross"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_NotesReceivableGross" xlink:to="lab_us-gaap_NotesReceivableGross" xlink:type="arc" order="1"/>
    <link:label id="lab_slm_LoansInRepaymentOriginatedFourYearsBeforeCurrentFiscalYear_b308f363-2b2b-4f92-b7a7-1a2a0fdff0d0_terseLabel_en-US" xlink:label="lab_slm_LoansInRepaymentOriginatedFourYearsBeforeCurrentFiscalYear" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Total Private Education Loans in forbearance, Year 5</link:label>
    <link:label id="lab_slm_LoansInRepaymentOriginatedFourYearsBeforeCurrentFiscalYear_label_en-US" xlink:label="lab_slm_LoansInRepaymentOriginatedFourYearsBeforeCurrentFiscalYear" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Loans In Repayment, Originated Four Years Before Current Fiscal Year</link:label>
    <link:label id="lab_slm_LoansInRepaymentOriginatedFourYearsBeforeCurrentFiscalYear_documentation_en-US" xlink:label="lab_slm_LoansInRepaymentOriginatedFourYearsBeforeCurrentFiscalYear" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Loans In Repayment, Originated Four Years Before Current Fiscal Year</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_slm_LoansInRepaymentOriginatedFourYearsBeforeCurrentFiscalYear" xlink:href="slm-20230331.xsd#slm_LoansInRepaymentOriginatedFourYearsBeforeCurrentFiscalYear"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_slm_LoansInRepaymentOriginatedFourYearsBeforeCurrentFiscalYear" xlink:to="lab_slm_LoansInRepaymentOriginatedFourYearsBeforeCurrentFiscalYear" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_CreditLossFinancialInstrumentTextBlock_62b4bdb1-1189-456b-b310-2fd26f9d0ea7_terseLabel_en-US" xlink:label="lab_us-gaap_CreditLossFinancialInstrumentTextBlock" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Unfunded Loan Commitments</link:label>
    <link:label id="lab_us-gaap_CreditLossFinancialInstrumentTextBlock_label_en-US" xlink:label="lab_us-gaap_CreditLossFinancialInstrumentTextBlock" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Credit Loss, Financial Instrument [Text Block]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CreditLossFinancialInstrumentTextBlock" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_CreditLossFinancialInstrumentTextBlock"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_CreditLossFinancialInstrumentTextBlock" xlink:to="lab_us-gaap_CreditLossFinancialInstrumentTextBlock" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest_18613056-e19e-4f95-8e18-c1263a84e1b9_totalLabel_en-US" xlink:label="lab_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest" xlink:role="http://www.xbrl.org/2003/role/totalLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Income before income tax expense</link:label>
    <link:label id="lab_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest_label_en-US" xlink:label="lab_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Income (Loss) from Continuing Operations before Income Taxes, Noncontrolling Interest</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest" xlink:to="lab_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_ScheduleOfFairValueHedgingInstrumentsStatementsOfFinancialPerformanceAndFinancialPositionLocationTableTextBlock_1261049c-fafe-43e0-a091-5a391bfbc16b_terseLabel_en-US" xlink:label="lab_us-gaap_ScheduleOfFairValueHedgingInstrumentsStatementsOfFinancialPerformanceAndFinancialPositionLocationTableTextBlock" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Schedule of Cumulative Basis Adjustments for Fair Value Hedges</link:label>
    <link:label id="lab_us-gaap_ScheduleOfFairValueHedgingInstrumentsStatementsOfFinancialPerformanceAndFinancialPositionLocationTableTextBlock_label_en-US" xlink:label="lab_us-gaap_ScheduleOfFairValueHedgingInstrumentsStatementsOfFinancialPerformanceAndFinancialPositionLocationTableTextBlock" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Schedule of Fair Value Hedging Instruments, Statements of Financial Performance and Financial Position, Location [Table Text Block]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfFairValueHedgingInstrumentsStatementsOfFinancialPerformanceAndFinancialPositionLocationTableTextBlock" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ScheduleOfFairValueHedgingInstrumentsStatementsOfFinancialPerformanceAndFinancialPositionLocationTableTextBlock"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_ScheduleOfFairValueHedgingInstrumentsStatementsOfFinancialPerformanceAndFinancialPositionLocationTableTextBlock" xlink:to="lab_us-gaap_ScheduleOfFairValueHedgingInstrumentsStatementsOfFinancialPerformanceAndFinancialPositionLocationTableTextBlock" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_PaymentsOfDividendsPreferredStockAndPreferenceStock_2b19cbb3-de9a-406b-b9d5-1b91cd56c90d_negatedLabel_en-US" xlink:label="lab_us-gaap_PaymentsOfDividendsPreferredStockAndPreferenceStock" xlink:role="http://www.xbrl.org/2009/role/negatedLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Preferred stock dividends paid</link:label>
    <link:label id="lab_us-gaap_PaymentsOfDividendsPreferredStockAndPreferenceStock_label_en-US" xlink:label="lab_us-gaap_PaymentsOfDividendsPreferredStockAndPreferenceStock" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Payments of Ordinary Dividends, Preferred Stock and Preference Stock</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsOfDividendsPreferredStockAndPreferenceStock" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_PaymentsOfDividendsPreferredStockAndPreferenceStock"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_PaymentsOfDividendsPreferredStockAndPreferenceStock" xlink:to="lab_us-gaap_PaymentsOfDividendsPreferredStockAndPreferenceStock" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_EarningsPerShareTextBlock_66ba5a26-42fe-471e-a7ce-e5ba493c4489_terseLabel_en-US" xlink:label="lab_us-gaap_EarningsPerShareTextBlock" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Earnings per Common Share</link:label>
    <link:label id="lab_us-gaap_EarningsPerShareTextBlock_label_en-US" xlink:label="lab_us-gaap_EarningsPerShareTextBlock" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Earnings Per Share [Text Block]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EarningsPerShareTextBlock" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_EarningsPerShareTextBlock"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_EarningsPerShareTextBlock" xlink:to="lab_us-gaap_EarningsPerShareTextBlock" xlink:type="arc" order="1"/>
    <link:label id="lab_slm_DerivativeInstrumentPercentofTotalNotionalDerivativeContracts_4794473c-9c76-4ced-a83e-6aaebf1b3fb1_terseLabel_en-US" xlink:label="lab_slm_DerivativeInstrumentPercentofTotalNotionalDerivativeContracts" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Percent of total notional derivative contracts</link:label>
    <link:label id="lab_slm_DerivativeInstrumentPercentofTotalNotionalDerivativeContracts_label_en-US" xlink:label="lab_slm_DerivativeInstrumentPercentofTotalNotionalDerivativeContracts" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Derivative Instrument, Percent of Total Notional Derivative Contracts</link:label>
    <link:label id="lab_slm_DerivativeInstrumentPercentofTotalNotionalDerivativeContracts_documentation_en-US" xlink:label="lab_slm_DerivativeInstrumentPercentofTotalNotionalDerivativeContracts" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Derivative Instrument, Percent of Total Notional Derivative Contracts</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_slm_DerivativeInstrumentPercentofTotalNotionalDerivativeContracts" xlink:href="slm-20230331.xsd#slm_DerivativeInstrumentPercentofTotalNotionalDerivativeContracts"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_slm_DerivativeInstrumentPercentofTotalNotionalDerivativeContracts" xlink:to="lab_slm_DerivativeInstrumentPercentofTotalNotionalDerivativeContracts" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_ComprehensiveIncomeNetOfTaxIncludingPortionAttributableToNoncontrollingInterest_bfae67b4-57aa-4b40-93f3-76a1b5d0c240_totalLabel_en-US" xlink:label="lab_us-gaap_ComprehensiveIncomeNetOfTaxIncludingPortionAttributableToNoncontrollingInterest" xlink:role="http://www.xbrl.org/2003/role/totalLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Total comprehensive income</link:label>
    <link:label id="lab_us-gaap_ComprehensiveIncomeNetOfTaxIncludingPortionAttributableToNoncontrollingInterest_label_en-US" xlink:label="lab_us-gaap_ComprehensiveIncomeNetOfTaxIncludingPortionAttributableToNoncontrollingInterest" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Comprehensive Income (Loss), Net of Tax, Including Portion Attributable to Noncontrolling Interest</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ComprehensiveIncomeNetOfTaxIncludingPortionAttributableToNoncontrollingInterest" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ComprehensiveIncomeNetOfTaxIncludingPortionAttributableToNoncontrollingInterest"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_ComprehensiveIncomeNetOfTaxIncludingPortionAttributableToNoncontrollingInterest" xlink:to="lab_us-gaap_ComprehensiveIncomeNetOfTaxIncludingPortionAttributableToNoncontrollingInterest" xlink:type="arc" order="1"/>
    <link:label id="lab_slm_CumulativeEffectPeriodOfAdoptionAdjustedPhaseInAmountsRemainingMember_21e2ddf2-f37f-41a2-a929-19157ee783e0_terseLabel_en-US" xlink:label="lab_slm_CumulativeEffectPeriodOfAdoptionAdjustedPhaseInAmountsRemainingMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Adjusted Phase-In Amounts Remaining</link:label>
    <link:label id="lab_slm_CumulativeEffectPeriodOfAdoptionAdjustedPhaseInAmountsRemainingMember_label_en-US" xlink:label="lab_slm_CumulativeEffectPeriodOfAdoptionAdjustedPhaseInAmountsRemainingMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Cumulative Effect, Period Of Adoption, Adjusted Phase-In Amounts Remaining [Member]</link:label>
    <link:label id="lab_slm_CumulativeEffectPeriodOfAdoptionAdjustedPhaseInAmountsRemainingMember_documentation_en-US" xlink:label="lab_slm_CumulativeEffectPeriodOfAdoptionAdjustedPhaseInAmountsRemainingMember" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Cumulative Effect, Period Of Adoption, Adjusted Phase-In Amounts Remaining</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_slm_CumulativeEffectPeriodOfAdoptionAdjustedPhaseInAmountsRemainingMember" xlink:href="slm-20230331.xsd#slm_CumulativeEffectPeriodOfAdoptionAdjustedPhaseInAmountsRemainingMember"/>
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    <link:label id="lab_slm_BrokeredDeposits_83f8655f-51e9-4e18-a2c0-9158ad118d02_terseLabel_en-US" xlink:label="lab_slm_BrokeredDeposits" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Brokered deposits</link:label>
    <link:label id="lab_slm_BrokeredDeposits_label_en-US" xlink:label="lab_slm_BrokeredDeposits" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Brokered Deposits</link:label>
    <link:label id="lab_slm_BrokeredDeposits_documentation_en-US" xlink:label="lab_slm_BrokeredDeposits" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Brokered Deposits</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_slm_BrokeredDeposits" xlink:href="slm-20230331.xsd#slm_BrokeredDeposits"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_slm_BrokeredDeposits" xlink:to="lab_slm_BrokeredDeposits" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_InterestBearingDomesticDepositMoneyMarket_6d746250-ff86-4fab-9a66-a97c9fbd77fe_terseLabel_en-US" xlink:label="lab_us-gaap_InterestBearingDomesticDepositMoneyMarket" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Money market</link:label>
    <link:label id="lab_us-gaap_InterestBearingDomesticDepositMoneyMarket_label_en-US" xlink:label="lab_us-gaap_InterestBearingDomesticDepositMoneyMarket" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Interest-Bearing Domestic Deposit, Money Market</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestBearingDomesticDepositMoneyMarket" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_InterestBearingDomesticDepositMoneyMarket"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_InterestBearingDomesticDepositMoneyMarket" xlink:to="lab_us-gaap_InterestBearingDomesticDepositMoneyMarket" xlink:type="arc" order="1"/>
    <link:label id="lab_slm_PercentageOfLoansInRepaymentOriginatedTwoYearsBeforeLatestFiscalYear_5f476721-5ed6-4591-b6b2-fe036deb4640_terseLabel_en-US" xlink:label="lab_slm_PercentageOfLoansInRepaymentOriginatedTwoYearsBeforeLatestFiscalYear" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Percentage of Private Education Loans in repayment, Year 3</link:label>
    <link:label id="lab_slm_PercentageOfLoansInRepaymentOriginatedTwoYearsBeforeLatestFiscalYear_label_en-US" xlink:label="lab_slm_PercentageOfLoansInRepaymentOriginatedTwoYearsBeforeLatestFiscalYear" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Percentage Of Loans In Repayment, Originated Two Years Before Latest Fiscal Year</link:label>
    <link:label id="lab_slm_PercentageOfLoansInRepaymentOriginatedTwoYearsBeforeLatestFiscalYear_documentation_en-US" xlink:label="lab_slm_PercentageOfLoansInRepaymentOriginatedTwoYearsBeforeLatestFiscalYear" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Percentage Of Loans In Repayment, Originated Two Years Before Latest Fiscal Year</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_slm_PercentageOfLoansInRepaymentOriginatedTwoYearsBeforeLatestFiscalYear" xlink:href="slm-20230331.xsd#slm_PercentageOfLoansInRepaymentOriginatedTwoYearsBeforeLatestFiscalYear"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_slm_PercentageOfLoansInRepaymentOriginatedTwoYearsBeforeLatestFiscalYear" xlink:to="lab_slm_PercentageOfLoansInRepaymentOriginatedTwoYearsBeforeLatestFiscalYear" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_StockIssuedDuringPeriodSharesNewIssues_3f0dae87-c150-4667-9b12-a274a6aabfb9_terseLabel_en-US" xlink:label="lab_us-gaap_StockIssuedDuringPeriodSharesNewIssues" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Issuance of common shares (in shares)</link:label>
    <link:label id="lab_us-gaap_StockIssuedDuringPeriodSharesNewIssues_5a8e9368-3918-4272-81b1-2dd11d363ec9_verboseLabel_en-US" xlink:label="lab_us-gaap_StockIssuedDuringPeriodSharesNewIssues" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Common shares issued (in shares)</link:label>
    <link:label id="lab_us-gaap_StockIssuedDuringPeriodSharesNewIssues_label_en-US" xlink:label="lab_us-gaap_StockIssuedDuringPeriodSharesNewIssues" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Stock Issued During Period, Shares, New Issues</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockIssuedDuringPeriodSharesNewIssues" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_StockIssuedDuringPeriodSharesNewIssues"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_StockIssuedDuringPeriodSharesNewIssues" xlink:to="lab_us-gaap_StockIssuedDuringPeriodSharesNewIssues" xlink:type="arc" order="1"/>
    <link:label id="lab_slm_DelinquenciesAsPercentageOfLoansInRepayment_ff6ea21a-5f1e-4ac3-98cc-6354cca4e09e_terseLabel_en-US" xlink:label="lab_slm_DelinquenciesAsPercentageOfLoansInRepayment" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Delinquent Private Education Loans in repayment as a percentage of Private Education Loans in repayment, total</link:label>
    <link:label id="lab_slm_DelinquenciesAsPercentageOfLoansInRepayment_label_en-US" xlink:label="lab_slm_DelinquenciesAsPercentageOfLoansInRepayment" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Delinquencies As Percentage Of Loans In Repayment</link:label>
    <link:label id="lab_slm_DelinquenciesAsPercentageOfLoansInRepayment_documentation_en-US" xlink:label="lab_slm_DelinquenciesAsPercentageOfLoansInRepayment" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Delinquencies as a percentage of loans in repayment.</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_slm_DelinquenciesAsPercentageOfLoansInRepayment" xlink:href="slm-20230331.xsd#slm_DelinquenciesAsPercentageOfLoansInRepayment"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_slm_DelinquenciesAsPercentageOfLoansInRepayment" xlink:to="lab_slm_DelinquenciesAsPercentageOfLoansInRepayment" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_CustomerRelationshipsMember_662cc92f-3e2e-41cf-89c8-c6f74fb09546_terseLabel_en-US" xlink:label="lab_us-gaap_CustomerRelationshipsMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Customer relationships</link:label>
    <link:label id="lab_us-gaap_CustomerRelationshipsMember_label_en-US" xlink:label="lab_us-gaap_CustomerRelationshipsMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Customer Relationships [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CustomerRelationshipsMember" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_CustomerRelationshipsMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_CustomerRelationshipsMember" xlink:to="lab_us-gaap_CustomerRelationshipsMember" xlink:type="arc" order="1"/>
    <link:label id="lab_dei_EntityAddressCityOrTown_9162e534-9b32-437e-ae5a-f51330cd5ba0_terseLabel_en-US" xlink:label="lab_dei_EntityAddressCityOrTown" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Entity Address, City or Town</link:label>
    <link:label id="lab_dei_EntityAddressCityOrTown_label_en-US" xlink:label="lab_dei_EntityAddressCityOrTown" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Entity Address, City or Town</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityAddressCityOrTown" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_EntityAddressCityOrTown"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_dei_EntityAddressCityOrTown" xlink:to="lab_dei_EntityAddressCityOrTown" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_AccumulatedGainLossNetCashFlowHedgeParentMember_3ced24e3-3ab2-4032-9faf-95e537f6c97a_terseLabel_en-US" xlink:label="lab_us-gaap_AccumulatedGainLossNetCashFlowHedgeParentMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Accumulated Gain (Loss), Net, Cash Flow Hedge, Parent</link:label>
    <link:label id="lab_us-gaap_AccumulatedGainLossNetCashFlowHedgeParentMember_label_en-US" xlink:label="lab_us-gaap_AccumulatedGainLossNetCashFlowHedgeParentMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Accumulated Gain (Loss), Net, Cash Flow Hedge, Parent [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccumulatedGainLossNetCashFlowHedgeParentMember" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AccumulatedGainLossNetCashFlowHedgeParentMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_AccumulatedGainLossNetCashFlowHedgeParentMember" xlink:to="lab_us-gaap_AccumulatedGainLossNetCashFlowHedgeParentMember" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_OperatingExpensesAbstract_af33408e-7587-4ee7-8453-9c1c7addac84_terseLabel_en-US" xlink:label="lab_us-gaap_OperatingExpensesAbstract" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Operating expenses:</link:label>
    <link:label id="lab_us-gaap_OperatingExpensesAbstract_label_en-US" xlink:label="lab_us-gaap_OperatingExpensesAbstract" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Operating Expenses [Abstract]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingExpensesAbstract" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_OperatingExpensesAbstract"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_OperatingExpensesAbstract" xlink:to="lab_us-gaap_OperatingExpensesAbstract" xlink:type="arc" order="1"/>
    <link:label id="lab_slm_FairValueDisclosureOffBalanceSheetRisksAmountLiabilityAdditionalCommitments_f55030a5-d305-4577-a5e0-0e3ab367b8d9_terseLabel_en-US" xlink:label="lab_slm_FairValueDisclosureOffBalanceSheetRisksAmountLiabilityAdditionalCommitments" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Provision/New commitments - net</link:label>
    <link:label id="lab_slm_FairValueDisclosureOffBalanceSheetRisksAmountLiabilityAdditionalCommitments_label_en-US" xlink:label="lab_slm_FairValueDisclosureOffBalanceSheetRisksAmountLiabilityAdditionalCommitments" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Fair Value Disclosure, Off-balance Sheet Risks, Amount, Liability, Additional Commitments</link:label>
    <link:label id="lab_slm_FairValueDisclosureOffBalanceSheetRisksAmountLiabilityAdditionalCommitments_documentation_en-US" xlink:label="lab_slm_FairValueDisclosureOffBalanceSheetRisksAmountLiabilityAdditionalCommitments" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Fair Value Disclosure, Off-balance Sheet Risks, Amount, Liability, Additional Commitments</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_slm_FairValueDisclosureOffBalanceSheetRisksAmountLiabilityAdditionalCommitments" xlink:href="slm-20230331.xsd#slm_FairValueDisclosureOffBalanceSheetRisksAmountLiabilityAdditionalCommitments"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_slm_FairValueDisclosureOffBalanceSheetRisksAmountLiabilityAdditionalCommitments" xlink:to="lab_slm_FairValueDisclosureOffBalanceSheetRisksAmountLiabilityAdditionalCommitments" xlink:type="arc" order="1"/>
    <link:label id="lab_slm_CreditQualityIndicatorsDomain_b899eab1-01c3-4097-91b6-36ec1f729f45_terseLabel_en-US" xlink:label="lab_slm_CreditQualityIndicatorsDomain" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Credit Quality Indicators [Domain]</link:label>
    <link:label id="lab_slm_CreditQualityIndicatorsDomain_label_en-US" xlink:label="lab_slm_CreditQualityIndicatorsDomain" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Credit Quality Indicators [Domain]</link:label>
    <link:label id="lab_slm_CreditQualityIndicatorsDomain_documentation_en-US" xlink:label="lab_slm_CreditQualityIndicatorsDomain" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Credit Quality Indicators [Domain]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_slm_CreditQualityIndicatorsDomain" xlink:href="slm-20230331.xsd#slm_CreditQualityIndicatorsDomain"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_slm_CreditQualityIndicatorsDomain" xlink:to="lab_slm_CreditQualityIndicatorsDomain" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_StatementOfFinancialPositionAbstract_6120662b-4002-4080-af81-f774e3b9a890_terseLabel_en-US" xlink:label="lab_us-gaap_StatementOfFinancialPositionAbstract" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Statement of Financial Position [Abstract]</link:label>
    <link:label id="lab_us-gaap_StatementOfFinancialPositionAbstract_label_en-US" xlink:label="lab_us-gaap_StatementOfFinancialPositionAbstract" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Statement of Financial Position [Abstract]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementOfFinancialPositionAbstract" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_StatementOfFinancialPositionAbstract"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_StatementOfFinancialPositionAbstract" xlink:to="lab_us-gaap_StatementOfFinancialPositionAbstract" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_UnrealizedGainLossOnDerivatives_d34d7848-801e-451e-8bdb-2101b593fbf7_negatedTerseLabel_en-US" xlink:label="lab_us-gaap_UnrealizedGainLossOnDerivatives" xlink:role="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Unrealized (gains) losses on derivatives and hedging activities, net</link:label>
    <link:label id="lab_us-gaap_UnrealizedGainLossOnDerivatives_label_en-US" xlink:label="lab_us-gaap_UnrealizedGainLossOnDerivatives" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Unrealized Gain (Loss) on Derivatives</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_UnrealizedGainLossOnDerivatives" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_UnrealizedGainLossOnDerivatives"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_UnrealizedGainLossOnDerivatives" xlink:to="lab_us-gaap_UnrealizedGainLossOnDerivatives" xlink:type="arc" order="1"/>
    <link:label id="lab_slm_ProceedsfromClaimpayments_3a503d29-f376-4f92-8d3d-f73fcfb2b381_terseLabel_en-US" xlink:label="lab_slm_ProceedsfromClaimpayments" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Proceeds from FFELP Loan claim payments</link:label>
    <link:label id="lab_slm_ProceedsfromClaimpayments_label_en-US" xlink:label="lab_slm_ProceedsfromClaimpayments" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Proceeds from Claim payments</link:label>
    <link:label id="lab_slm_ProceedsfromClaimpayments_documentation_en-US" xlink:label="lab_slm_ProceedsfromClaimpayments" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Proceeds from Claim payments</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_slm_ProceedsfromClaimpayments" xlink:href="slm-20230331.xsd#slm_ProceedsfromClaimpayments"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_slm_ProceedsfromClaimpayments" xlink:to="lab_slm_ProceedsfromClaimpayments" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_TreasuryStockCommonMember_380128f7-d7e2-4eec-994b-d3cbf02decb7_terseLabel_en-US" xlink:label="lab_us-gaap_TreasuryStockCommonMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Treasury Stock</link:label>
    <link:label id="lab_us-gaap_TreasuryStockCommonMember_label_en-US" xlink:label="lab_us-gaap_TreasuryStockCommonMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Treasury Stock, Common [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_TreasuryStockCommonMember" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_TreasuryStockCommonMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_TreasuryStockCommonMember" xlink:to="lab_us-gaap_TreasuryStockCommonMember" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_AdjustmentsForNewAccountingPronouncementsAxis_afe3f428-9c7b-4aed-b7ea-47a29a73547e_terseLabel_en-US" xlink:label="lab_us-gaap_AdjustmentsForNewAccountingPronouncementsAxis" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Adjustments for New Accounting Pronouncements [Axis]</link:label>
    <link:label id="lab_us-gaap_AdjustmentsForNewAccountingPronouncementsAxis_label_en-US" xlink:label="lab_us-gaap_AdjustmentsForNewAccountingPronouncementsAxis" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Accounting Standards Update [Axis]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AdjustmentsForNewAccountingPronouncementsAxis" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AdjustmentsForNewAccountingPronouncementsAxis"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_AdjustmentsForNewAccountingPronouncementsAxis" xlink:to="lab_us-gaap_AdjustmentsForNewAccountingPronouncementsAxis" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_SharePrice_406e0d69-0734-40a6-a1fd-a6d4295c22c5_terseLabel_en-US" xlink:label="lab_us-gaap_SharePrice" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Common stock closing price (in dollars per share)</link:label>
    <link:label id="lab_us-gaap_SharePrice_label_en-US" xlink:label="lab_us-gaap_SharePrice" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Share Price</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SharePrice" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_SharePrice"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_SharePrice" xlink:to="lab_us-gaap_SharePrice" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_ConvertibleDebtSecuritiesMember_ae6a4b91-0648-40c0-88c3-2468e4e2419f_terseLabel_en-US" xlink:label="lab_us-gaap_ConvertibleDebtSecuritiesMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Convertible Debt Securities</link:label>
    <link:label id="lab_us-gaap_ConvertibleDebtSecuritiesMember_label_en-US" xlink:label="lab_us-gaap_ConvertibleDebtSecuritiesMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Convertible Debt Securities [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ConvertibleDebtSecuritiesMember" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ConvertibleDebtSecuritiesMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_ConvertibleDebtSecuritiesMember" xlink:to="lab_us-gaap_ConvertibleDebtSecuritiesMember" xlink:type="arc" order="1"/>
    <link:label id="lab_slm_DenominatorAbstract_7f2e2c4c-bcf7-4948-af49-cb9b1104eacf_terseLabel_en-US" xlink:label="lab_slm_DenominatorAbstract" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Denominator:</link:label>
    <link:label id="lab_slm_DenominatorAbstract_label_en-US" xlink:label="lab_slm_DenominatorAbstract" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Denominator [Abstract]</link:label>
    <link:label id="lab_slm_DenominatorAbstract_documentation_en-US" xlink:label="lab_slm_DenominatorAbstract" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Denominator [Abstract]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_slm_DenominatorAbstract" xlink:href="slm-20230331.xsd#slm_DenominatorAbstract"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_slm_DenominatorAbstract" xlink:to="lab_slm_DenominatorAbstract" xlink:type="arc" order="1"/>
    <link:label id="lab_slm_FinancingReceivablesAmortizedCostBasisTableTextBlock_d773755b-ca0a-4a4e-a20f-709c21ba9be8_terseLabel_en-US" xlink:label="lab_slm_FinancingReceivablesAmortizedCostBasisTableTextBlock" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Schedule of Amortized Cost Basis of Financing Receivables</link:label>
    <link:label id="lab_slm_FinancingReceivablesAmortizedCostBasisTableTextBlock_label_en-US" xlink:label="lab_slm_FinancingReceivablesAmortizedCostBasisTableTextBlock" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Financing Receivables, Amortized Cost Basis [Table Text Block]</link:label>
    <link:label id="lab_slm_FinancingReceivablesAmortizedCostBasisTableTextBlock_documentation_en-US" xlink:label="lab_slm_FinancingReceivablesAmortizedCostBasisTableTextBlock" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Financing Receivables, Amortized Cost Basis</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_slm_FinancingReceivablesAmortizedCostBasisTableTextBlock" xlink:href="slm-20230331.xsd#slm_FinancingReceivablesAmortizedCostBasisTableTextBlock"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_slm_FinancingReceivablesAmortizedCostBasisTableTextBlock" xlink:to="lab_slm_FinancingReceivablesAmortizedCostBasisTableTextBlock" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_TreasuryStockCommonShares_0ddb3bd8-5e8b-4f78-9f7f-60b7f0386722_terseLabel_en-US" xlink:label="lab_us-gaap_TreasuryStockCommonShares" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Common stock held in treasury (in shares)</link:label>
    <link:label id="lab_us-gaap_TreasuryStockCommonShares_eee115c8-d0fb-45a8-b7be-708f6e61da93_negatedPeriodStartLabel_en-US" xlink:label="lab_us-gaap_TreasuryStockCommonShares" xlink:role="http://www.xbrl.org/2009/role/negatedPeriodStartLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Beginning balance (in shares)</link:label>
    <link:label id="lab_us-gaap_TreasuryStockCommonShares_1704b6e9-3ea4-4677-87eb-4ef7e4c10ca7_negatedPeriodEndLabel_en-US" xlink:label="lab_us-gaap_TreasuryStockCommonShares" xlink:role="http://www.xbrl.org/2009/role/negatedPeriodEndLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Ending Balance (in shares)</link:label>
    <link:label id="lab_us-gaap_TreasuryStockCommonShares_label_en-US" xlink:label="lab_us-gaap_TreasuryStockCommonShares" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Treasury Stock, Common, Shares</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_TreasuryStockCommonShares" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_TreasuryStockCommonShares"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_TreasuryStockCommonShares" xlink:to="lab_us-gaap_TreasuryStockCommonShares" xlink:type="arc" order="1"/>
    <link:label id="lab_slm_RetailandOtherDeposits_4847aad8-d3b0-456f-9958-68d9b1b27426_terseLabel_en-US" xlink:label="lab_slm_RetailandOtherDeposits" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Retail and other deposits</link:label>
    <link:label id="lab_slm_RetailandOtherDeposits_label_en-US" xlink:label="lab_slm_RetailandOtherDeposits" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Retail and Other Deposits</link:label>
    <link:label id="lab_slm_RetailandOtherDeposits_documentation_en-US" xlink:label="lab_slm_RetailandOtherDeposits" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Retail and Other Deposits</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_slm_RetailandOtherDeposits" xlink:href="slm-20230331.xsd#slm_RetailandOtherDeposits"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_slm_RetailandOtherDeposits" xlink:to="lab_slm_RetailandOtherDeposits" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_OtherInvestmentNotReadilyMarketableFairValue_2f81780c-0c80-4ea6-b287-029d53cc5b50_terseLabel_en-US" xlink:label="lab_us-gaap_OtherInvestmentNotReadilyMarketableFairValue" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Non-marketable securities investment</link:label>
    <link:label id="lab_us-gaap_OtherInvestmentNotReadilyMarketableFairValue_label_en-US" xlink:label="lab_us-gaap_OtherInvestmentNotReadilyMarketableFairValue" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Other Investment Not Readily Marketable, Fair Value</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherInvestmentNotReadilyMarketableFairValue" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_OtherInvestmentNotReadilyMarketableFairValue"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_OtherInvestmentNotReadilyMarketableFairValue" xlink:to="lab_us-gaap_OtherInvestmentNotReadilyMarketableFairValue" xlink:type="arc" order="1"/>
    <link:label id="lab_slm_PrivateEducationLoanSecuritizationMember_da19c485-2e27-4740-ac2d-a9ecb48906ba_terseLabel_en-US" xlink:label="lab_slm_PrivateEducationLoanSecuritizationMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Private Education Loan term securitizations</link:label>
    <link:label id="lab_slm_PrivateEducationLoanSecuritizationMember_label_en-US" xlink:label="lab_slm_PrivateEducationLoanSecuritizationMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Private Education Loan Securitization [Member]</link:label>
    <link:label id="lab_slm_PrivateEducationLoanSecuritizationMember_documentation_en-US" xlink:label="lab_slm_PrivateEducationLoanSecuritizationMember" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Private Education Loan Securitization [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_slm_PrivateEducationLoanSecuritizationMember" xlink:href="slm-20230331.xsd#slm_PrivateEducationLoanSecuritizationMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_slm_PrivateEducationLoanSecuritizationMember" xlink:to="lab_slm_PrivateEducationLoanSecuritizationMember" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_AllowanceForCreditLossesTextBlock_3f54ec3c-8474-4330-8429-4a882ff085bf_terseLabel_en-US" xlink:label="lab_us-gaap_AllowanceForCreditLossesTextBlock" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Allowance for Credit Losses</link:label>
    <link:label id="lab_us-gaap_AllowanceForCreditLossesTextBlock_label_en-US" xlink:label="lab_us-gaap_AllowanceForCreditLossesTextBlock" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Allowance for Credit Losses [Text Block]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AllowanceForCreditLossesTextBlock" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AllowanceForCreditLossesTextBlock"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_AllowanceForCreditLossesTextBlock" xlink:to="lab_us-gaap_AllowanceForCreditLossesTextBlock" xlink:type="arc" order="1"/>
    <link:label id="lab_slm_PeriodofLoansPastDueThatHaveAccruedInterest_a8996700-39bd-4000-969a-6229c64a0fc5_terseLabel_en-US" xlink:label="lab_slm_PeriodofLoansPastDueThatHaveAccruedInterest" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Period of loans past due that have accrued interest</link:label>
    <link:label id="lab_slm_PeriodofLoansPastDueThatHaveAccruedInterest_label_en-US" xlink:label="lab_slm_PeriodofLoansPastDueThatHaveAccruedInterest" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Period of Loans Past Due That Have Accrued Interest</link:label>
    <link:label id="lab_slm_PeriodofLoansPastDueThatHaveAccruedInterest_documentation_en-US" xlink:label="lab_slm_PeriodofLoansPastDueThatHaveAccruedInterest" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Period of Loans Past Due That Have Accrued Interest</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_slm_PeriodofLoansPastDueThatHaveAccruedInterest" xlink:href="slm-20230331.xsd#slm_PeriodofLoansPastDueThatHaveAccruedInterest"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_slm_PeriodofLoansPastDueThatHaveAccruedInterest" xlink:to="lab_slm_PeriodofLoansPastDueThatHaveAccruedInterest" xlink:type="arc" order="1"/>
    <link:label id="lab_dei_EntityInformationLineItems_86160d15-f18a-4a34-a357-58d38bfc0ea9_terseLabel_en-US" xlink:label="lab_dei_EntityInformationLineItems" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Entity Information [Line Items]</link:label>
    <link:label id="lab_dei_EntityInformationLineItems_label_en-US" xlink:label="lab_dei_EntityInformationLineItems" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Entity Information [Line Items]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityInformationLineItems" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_EntityInformationLineItems"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_dei_EntityInformationLineItems" xlink:to="lab_dei_EntityInformationLineItems" xlink:type="arc" order="1"/>
    <link:label id="lab_slm_Maturity2049Member_541e3403-64e2-4c89-aa2f-2f3f0d34fed2_terseLabel_en-US" xlink:label="lab_slm_Maturity2049Member" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">2049</link:label>
    <link:label id="lab_slm_Maturity2049Member_label_en-US" xlink:label="lab_slm_Maturity2049Member" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Maturity 2049 [Member]</link:label>
    <link:label id="lab_slm_Maturity2049Member_documentation_en-US" xlink:label="lab_slm_Maturity2049Member" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Maturity 2049 [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_slm_Maturity2049Member" xlink:href="slm-20230331.xsd#slm_Maturity2049Member"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_slm_Maturity2049Member" xlink:to="lab_slm_Maturity2049Member" xlink:type="arc" order="1"/>
    <link:label id="lab_slm_FinancingReceivableAccruedInterestOriginationVintageOriginatedInFiscalYearBeforeLatestFiscalYear_dc89ea8d-f297-4331-aff5-500053dc6dc5_terseLabel_en-US" xlink:label="lab_slm_FinancingReceivableAccruedInterestOriginationVintageOriginatedInFiscalYearBeforeLatestFiscalYear" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Total accrued interest by origination vintage, Year 2</link:label>
    <link:label id="lab_slm_FinancingReceivableAccruedInterestOriginationVintageOriginatedInFiscalYearBeforeLatestFiscalYear_label_en-US" xlink:label="lab_slm_FinancingReceivableAccruedInterestOriginationVintageOriginatedInFiscalYearBeforeLatestFiscalYear" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Financing Receivable, Accrued Interest, Origination Vintage, Originated in Fiscal Year before Latest Fiscal Year</link:label>
    <link:label id="lab_slm_FinancingReceivableAccruedInterestOriginationVintageOriginatedInFiscalYearBeforeLatestFiscalYear_documentation_en-US" xlink:label="lab_slm_FinancingReceivableAccruedInterestOriginationVintageOriginatedInFiscalYearBeforeLatestFiscalYear" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Financing Receivable, Accrued Interest, Origination Vintage, Originated in Fiscal Year before Latest Fiscal Year</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_slm_FinancingReceivableAccruedInterestOriginationVintageOriginatedInFiscalYearBeforeLatestFiscalYear" xlink:href="slm-20230331.xsd#slm_FinancingReceivableAccruedInterestOriginationVintageOriginatedInFiscalYearBeforeLatestFiscalYear"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_slm_FinancingReceivableAccruedInterestOriginationVintageOriginatedInFiscalYearBeforeLatestFiscalYear" xlink:to="lab_slm_FinancingReceivableAccruedInterestOriginationVintageOriginatedInFiscalYearBeforeLatestFiscalYear" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_FinancingReceivableExcludingAccruedInterestBeforeAllowanceForCreditLoss_0619e2b7-09dd-4766-8b8e-77eedb370dda_terseLabel_en-US" xlink:label="lab_us-gaap_FinancingReceivableExcludingAccruedInterestBeforeAllowanceForCreditLoss" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Loan type</link:label>
    <link:label id="lab_us-gaap_FinancingReceivableExcludingAccruedInterestBeforeAllowanceForCreditLoss_2a8607eb-169f-4268-9f7e-10a32a18de60_totalLabel_en-US" xlink:label="lab_us-gaap_FinancingReceivableExcludingAccruedInterestBeforeAllowanceForCreditLoss" xlink:role="http://www.xbrl.org/2003/role/totalLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Loan type</link:label>
    <link:label id="lab_us-gaap_FinancingReceivableExcludingAccruedInterestBeforeAllowanceForCreditLoss_label_en-US" xlink:label="lab_us-gaap_FinancingReceivableExcludingAccruedInterestBeforeAllowanceForCreditLoss" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Financing Receivable, Excluding Accrued Interest, before Allowance for Credit Loss</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinancingReceivableExcludingAccruedInterestBeforeAllowanceForCreditLoss" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_FinancingReceivableExcludingAccruedInterestBeforeAllowanceForCreditLoss"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_FinancingReceivableExcludingAccruedInterestBeforeAllowanceForCreditLoss" xlink:to="lab_us-gaap_FinancingReceivableExcludingAccruedInterestBeforeAllowanceForCreditLoss" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_ScheduleOfComplianceWithRegulatoryCapitalRequirementsUnderBankingRegulationsTextBlock_35f4627c-212c-4449-b46a-123f19e56286_terseLabel_en-US" xlink:label="lab_us-gaap_ScheduleOfComplianceWithRegulatoryCapitalRequirementsUnderBankingRegulationsTextBlock" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Schedule of Compliance with Regulatory Capital Requirements Under Banking Regulations</link:label>
    <link:label id="lab_us-gaap_ScheduleOfComplianceWithRegulatoryCapitalRequirementsUnderBankingRegulationsTextBlock_label_en-US" xlink:label="lab_us-gaap_ScheduleOfComplianceWithRegulatoryCapitalRequirementsUnderBankingRegulationsTextBlock" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Schedule of Compliance with Regulatory Capital Requirements under Banking Regulations [Table Text Block]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfComplianceWithRegulatoryCapitalRequirementsUnderBankingRegulationsTextBlock" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ScheduleOfComplianceWithRegulatoryCapitalRequirementsUnderBankingRegulationsTextBlock"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_ScheduleOfComplianceWithRegulatoryCapitalRequirementsUnderBankingRegulationsTextBlock" xlink:to="lab_us-gaap_ScheduleOfComplianceWithRegulatoryCapitalRequirementsUnderBankingRegulationsTextBlock" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_CashAndCashEquivalentsFairValueDisclosure_6c6c3c86-8337-43d8-811a-dbff8921cf25_terseLabel_en-US" xlink:label="lab_us-gaap_CashAndCashEquivalentsFairValueDisclosure" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Cash and cash equivalents</link:label>
    <link:label id="lab_us-gaap_CashAndCashEquivalentsFairValueDisclosure_label_en-US" xlink:label="lab_us-gaap_CashAndCashEquivalentsFairValueDisclosure" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Cash and Cash Equivalents, Fair Value Disclosure</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashAndCashEquivalentsFairValueDisclosure" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_CashAndCashEquivalentsFairValueDisclosure"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_CashAndCashEquivalentsFairValueDisclosure" xlink:to="lab_us-gaap_CashAndCashEquivalentsFairValueDisclosure" xlink:type="arc" order="1"/>
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    <link:label id="lab_slm_FinancingReceivableLoansInForbearanceYearFourOriginatedThreeYearsBeforeCurrentFiscalYear_c9f0c97a-5743-4177-ab00-0b646d5a7a30_terseLabel_en-US" xlink:label="lab_slm_FinancingReceivableLoansInForbearanceYearFourOriginatedThreeYearsBeforeCurrentFiscalYear" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Total Private Education Loans in forbearance, Year 4</link:label>
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    <link:label id="lab_us-gaap_DebtSecuritiesAvailableForSaleContinuousUnrealizedLossPosition12MonthsOrLonger_23df1646-6307-4d2a-84c0-937b40f3b6b7_terseLabel_en-US" xlink:label="lab_us-gaap_DebtSecuritiesAvailableForSaleContinuousUnrealizedLossPosition12MonthsOrLonger" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Estimated Fair Value</link:label>
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    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtSecuritiesAvailableForSaleContinuousUnrealizedLossPosition12MonthsOrLonger" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_DebtSecuritiesAvailableForSaleContinuousUnrealizedLossPosition12MonthsOrLonger"/>
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    <link:label id="lab_slm_PercentageOfLoansInRepaymentBeforeAllowanceForCreditLoss_43d5ae80-582d-4438-b782-ab768b352a8c_terseLabel_en-US" xlink:label="lab_slm_PercentageOfLoansInRepaymentBeforeAllowanceForCreditLoss" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Percentage of Private Education Loans in repayment</link:label>
    <link:label id="lab_slm_PercentageOfLoansInRepaymentBeforeAllowanceForCreditLoss_label_en-US" xlink:label="lab_slm_PercentageOfLoansInRepaymentBeforeAllowanceForCreditLoss" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Percentage Of Loans In Repayment, Before Allowance For Credit Loss</link:label>
    <link:label id="lab_slm_PercentageOfLoansInRepaymentBeforeAllowanceForCreditLoss_documentation_en-US" xlink:label="lab_slm_PercentageOfLoansInRepaymentBeforeAllowanceForCreditLoss" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Percentage Of Loans In Repayment, Before Allowance For Credit Loss</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_slm_PercentageOfLoansInRepaymentBeforeAllowanceForCreditLoss" xlink:href="slm-20230331.xsd#slm_PercentageOfLoansInRepaymentBeforeAllowanceForCreditLoss"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_slm_PercentageOfLoansInRepaymentBeforeAllowanceForCreditLoss" xlink:to="lab_slm_PercentageOfLoansInRepaymentBeforeAllowanceForCreditLoss" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_NoninterestExpenseAbstract_0323a226-6eea-4a5d-8797-19ef1e2e6f08_terseLabel_en-US" xlink:label="lab_us-gaap_NoninterestExpenseAbstract" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Non-interest expenses:</link:label>
    <link:label id="lab_us-gaap_NoninterestExpenseAbstract_label_en-US" xlink:label="lab_us-gaap_NoninterestExpenseAbstract" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Noninterest Expense [Abstract]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NoninterestExpenseAbstract" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_NoninterestExpenseAbstract"/>
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    <link:label id="lab_slm_FinancingReceivableAccruedInterestOriginationVintageOriginatedFourYearsBeforeLatestFiscalYear_feb3e1d5-82c9-4fdf-bcbd-9a6b49979703_terseLabel_en-US" xlink:label="lab_slm_FinancingReceivableAccruedInterestOriginationVintageOriginatedFourYearsBeforeLatestFiscalYear" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Total accrued interest by origination vintage, Year 5</link:label>
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    <link:label id="lab_slm_FinancingReceivableAccruedInterestOriginationVintageOriginatedFourYearsBeforeLatestFiscalYear_documentation_en-US" xlink:label="lab_slm_FinancingReceivableAccruedInterestOriginationVintageOriginatedFourYearsBeforeLatestFiscalYear" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Financing Receivable, Accrued interest, Origination Vintage, Originated Four Years before Latest Fiscal Year</link:label>
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    <link:label id="lab_slm_FinancingReceivableAllowanceForCreditLossRecoveryOriginatedFourYearsBeforeCurrentFiscalYear_c76558eb-9858-42db-bd57-05337178c15a_terseLabel_en-US" xlink:label="lab_slm_FinancingReceivableAllowanceForCreditLossRecoveryOriginatedFourYearsBeforeCurrentFiscalYear" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Current period recoveries, Year 5</link:label>
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    <link:label id="lab_slm_FinancingReceivableAllowanceForCreditLossRecoveryOriginatedFourYearsBeforeCurrentFiscalYear_documentation_en-US" xlink:label="lab_slm_FinancingReceivableAllowanceForCreditLossRecoveryOriginatedFourYearsBeforeCurrentFiscalYear" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Financing Receivable, Allowance for Credit Loss, Recovery, Originated Four Years Before Current Fiscal Year</link:label>
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    <link:label id="lab_us-gaap_QualifiedAffordableHousingProjectInvestmentsCommitment_5014aace-fffc-4396-9305-1b7283efdf0d_terseLabel_en-US" xlink:label="lab_us-gaap_QualifiedAffordableHousingProjectInvestmentsCommitment" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Low income housing tax credit investments, liability for unfunded commitments</link:label>
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    <link:label id="lab_us-gaap_DebtLongtermAndShorttermCombinedAmount_b5945f46-ad42-4957-9f67-4d9827ff07f3_totalLabel_en-US" xlink:label="lab_us-gaap_DebtLongtermAndShorttermCombinedAmount" xlink:role="http://www.xbrl.org/2003/role/totalLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Total</link:label>
    <link:label id="lab_us-gaap_DebtLongtermAndShorttermCombinedAmount_label_en-US" xlink:label="lab_us-gaap_DebtLongtermAndShorttermCombinedAmount" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Debt, Long-Term and Short-Term, Combined Amount</link:label>
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    <link:label id="lab_us-gaap_ScheduleOfTreasuryStockByClassTextBlock_ae6831bb-0d62-4f6d-bb25-3d71544a45af_terseLabel_en-US" xlink:label="lab_us-gaap_ScheduleOfTreasuryStockByClassTextBlock" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Schedule of Common Share Repurchases</link:label>
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    <link:label id="lab_slm_FinancingReceivableAfterAllowanceForCreditLossOriginatedFourYearsBeforeCurrentFiscalYear_942d20c7-711c-4dbd-8680-b2a773dcca3e_terseLabel_en-US" xlink:label="lab_slm_FinancingReceivableAfterAllowanceForCreditLossOriginatedFourYearsBeforeCurrentFiscalYear" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Private Education Loans, net, Year 5</link:label>
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    <link:label id="lab_slm_NetProceedsFromSalesOfStudentLoansHeldForSaleCapitalizedInterest_3e675098-4c98-4590-bd9d-ca32840f32be_terseLabel_en-US" xlink:label="lab_slm_NetProceedsFromSalesOfStudentLoansHeldForSaleCapitalizedInterest" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Net proceeds from sales of loans held for investment, capitalized interest</link:label>
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    <link:label id="lab_slm_LoansInForbearanceAsAPercentageOfPrivateEducationLoansInRepaymentAndForbearanceOriginatedThreeYearsBeforeCurrentFiscalYear_22a76da6-9f85-42c4-834c-32682b2f2e93_terseLabel_en-US" xlink:label="lab_slm_LoansInForbearanceAsAPercentageOfPrivateEducationLoansInRepaymentAndForbearanceOriginatedThreeYearsBeforeCurrentFiscalYear" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Loans in forbearance as a percentage of loans in repayment and forbearance, Year 4</link:label>
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    <link:label id="lab_slm_AccruedInterestReceivableFairValueDisclosure_51bcaa5e-0503-4b92-8581-245313d8a9b1_terseLabel_en-US" xlink:label="lab_slm_AccruedInterestReceivableFairValueDisclosure" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Accrued interest receivable</link:label>
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    <link:label id="lab_slm_FinancingReceivableAllowanceForCreditLossOriginatedTwoYearsBeforeCurrentFiscalYear_1bf680d9-8989-4013-8329-0a2c3b09060a_negatedTerseLabel_en-US" xlink:label="lab_slm_FinancingReceivableAllowanceForCreditLossOriginatedTwoYearsBeforeCurrentFiscalYear" xlink:role="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Private Education Loans allowance for losses, Year 3</link:label>
    <link:label id="lab_slm_FinancingReceivableAllowanceForCreditLossOriginatedTwoYearsBeforeCurrentFiscalYear_label_en-US" xlink:label="lab_slm_FinancingReceivableAllowanceForCreditLossOriginatedTwoYearsBeforeCurrentFiscalYear" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Financing Receivable, Allowance For Credit Loss, Originated Two Years Before Current Fiscal Year</link:label>
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    <link:label id="lab_slm_CreditQualityIndicatorsAxis_6427285d-bc81-4a49-9caf-811b8df412fc_terseLabel_en-US" xlink:label="lab_slm_CreditQualityIndicatorsAxis" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Credit Quality Indicators [Axis]</link:label>
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    <link:label id="lab_slm_CreditQualityIndicatorsAxis_documentation_en-US" xlink:label="lab_slm_CreditQualityIndicatorsAxis" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Credit Quality Indicators [Axis]</link:label>
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    <link:label id="lab_us-gaap_VariableRateDomain_a1144d5a-2095-4c26-a95b-2a7345acc77a_terseLabel_en-US" xlink:label="lab_us-gaap_VariableRateDomain" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Variable Rate [Domain]</link:label>
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    <link:label id="lab_slm_PrivateEducationLoansAtOrigination_e4457bca-ea8b-4570-bf09-48d427e99dac_terseLabel_en-US" xlink:label="lab_slm_PrivateEducationLoansAtOrigination" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Private education loans at origination</link:label>
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    <link:label id="lab_us-gaap_AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedLossBeforeTax_365e6187-e136-4567-b7a4-24c0237afb38_negatedTerseLabel_en-US" xlink:label="lab_us-gaap_AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedLossBeforeTax" xlink:role="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Gross Unrealized Losses</link:label>
    <link:label id="lab_us-gaap_AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedLossBeforeTax_label_en-US" xlink:label="lab_us-gaap_AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedLossBeforeTax" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Debt Securities, Available-for-Sale, Accumulated Gross Unrealized Loss, before Tax</link:label>
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    <link:label id="lab_us-gaap_AccumulatedOtherComprehensiveIncomeMember_0227da76-4cbf-4417-a454-0096e40e8d47_terseLabel_en-US" xlink:label="lab_us-gaap_AccumulatedOtherComprehensiveIncomeMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Accumulated Other Comprehensive Loss</link:label>
    <link:label id="lab_us-gaap_AccumulatedOtherComprehensiveIncomeMember_label_en-US" xlink:label="lab_us-gaap_AccumulatedOtherComprehensiveIncomeMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">AOCI Attributable to Parent [Member]</link:label>
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    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_AccumulatedOtherComprehensiveIncomeMember" xlink:to="lab_us-gaap_AccumulatedOtherComprehensiveIncomeMember" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_FinancingReceivablePortfolioSegmentAxis_fe5e4cce-b8f6-4f4a-a63d-7560c874b775_terseLabel_en-US" xlink:label="lab_us-gaap_FinancingReceivablePortfolioSegmentAxis" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Financing Receivable Portfolio Segment [Axis]</link:label>
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    <link:label id="lab_dei_DocumentTransitionReport_e060ef61-c82d-4670-8be4-bb06ea076162_terseLabel_en-US" xlink:label="lab_dei_DocumentTransitionReport" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Document Transition Report</link:label>
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    <link:label id="lab_us-gaap_OffBalanceSheetCreditLossLiabilityCreditLossExpenseReversal_acb33bc0-3ccd-494b-b2a1-0305325bfd28_terseLabel_en-US" xlink:label="lab_us-gaap_OffBalanceSheetCreditLossLiabilityCreditLossExpenseReversal" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Provision/New commitments - net</link:label>
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    <link:label id="lab_dei_LocalPhoneNumber_fd71ea38-7d52-41a9-985e-67f4d1851422_terseLabel_en-US" xlink:label="lab_dei_LocalPhoneNumber" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Local Phone Number</link:label>
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    <link:label id="lab_slm_CommonStockParValue20PerShareMember_e8cf0989-293a-4880-9af0-5a6369a61082_terseLabel_en-US" xlink:label="lab_slm_CommonStockParValue20PerShareMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Common stock, par value $.20 per share</link:label>
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    <link:label id="lab_us-gaap_DerivativeGainLossStatementOfIncomeOrComprehensiveIncomeExtensibleEnumeration_b5cd14c8-e379-41b0-b1a5-4574a03d5969_terseLabel_en-US" xlink:label="lab_us-gaap_DerivativeGainLossStatementOfIncomeOrComprehensiveIncomeExtensibleEnumeration" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Derivative, Gain (Loss), Statement of Income or Comprehensive Income [Extensible Enumeration]</link:label>
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    <link:label id="lab_us-gaap_GoodwillAndIntangibleAssetsDisclosureTextBlock_bf14f2a3-6d65-4838-acbc-a8032c8d76b5_terseLabel_en-US" xlink:label="lab_us-gaap_GoodwillAndIntangibleAssetsDisclosureTextBlock" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Goodwill and Acquired Intangible Assets</link:label>
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    <link:label id="lab_slm_AllowanceCoverageOfChargeOffsEndingLoansInRepayment_a24dab06-5228-4c81-8b50-77b738ec2735_terseLabel_en-US" xlink:label="lab_slm_AllowanceCoverageOfChargeOffsEndingLoansInRepayment" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Ending loans in repayment</link:label>
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    <link:loc xlink:type="locator" xlink:label="loc_slm_AllowanceCoverageOfChargeOffsEndingLoansInRepayment" xlink:href="slm-20230331.xsd#slm_AllowanceCoverageOfChargeOffsEndingLoansInRepayment"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_slm_AllowanceCoverageOfChargeOffsEndingLoansInRepayment" xlink:to="lab_slm_AllowanceCoverageOfChargeOffsEndingLoansInRepayment" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_InterestBearingDomesticDepositSavings_0a65f496-e42e-43ed-86df-c8072717e025_terseLabel_en-US" xlink:label="lab_us-gaap_InterestBearingDomesticDepositSavings" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Savings</link:label>
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    <link:label id="lab_us-gaap_InterestRateBelowMarketReductionMember_d4ab7f4e-f16d-414f-af2b-664253636510_terseLabel_en-US" xlink:label="lab_us-gaap_InterestRateBelowMarketReductionMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Interest Rate Reduction</link:label>
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    <link:label id="lab_slm_LoansInForbearanceAsAPercentageOfPrivateEducationLoansInRepaymentAndForbearance_2c1c6eef-c1b0-4500-86e7-d6ed335da8da_terseLabel_en-US" xlink:label="lab_slm_LoansInForbearanceAsAPercentageOfPrivateEducationLoansInRepaymentAndForbearance" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Loans in forbearance as a percentage of loans in repayment and forbearance</link:label>
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    <link:label id="lab_us-gaap_ScheduleOfAvailableForSaleSecuritiesLineItems_6e3b5438-eef9-4e87-aa4b-08af03a914ec_terseLabel_en-US" xlink:label="lab_us-gaap_ScheduleOfAvailableForSaleSecuritiesLineItems" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Debt Securities, Available-for-sale [Line Items]</link:label>
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    <link:label id="lab_us-gaap_CommonStockDividendsPerShareCashPaid_5669f242-5e61-4dab-b476-7ca893958e89_terseLabel_en-US" xlink:label="lab_us-gaap_CommonStockDividendsPerShareCashPaid" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Common stock dividend (in dollars per share)</link:label>
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    <link:label id="lab_us-gaap_CarryingReportedAmountFairValueDisclosureMember_label_en-US" xlink:label="lab_us-gaap_CarryingReportedAmountFairValueDisclosureMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Reported Value Measurement [Member]</link:label>
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    <link:label id="lab_slm_FinancingReceivableLoansInForbearanceYearSixOriginatedMoreThanSixYearsBeforeCurrentFiscalYear_5911d4f4-5b8a-40ec-9c71-00f7787aa075_terseLabel_en-US" xlink:label="lab_slm_FinancingReceivableLoansInForbearanceYearSixOriginatedMoreThanSixYearsBeforeCurrentFiscalYear" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Total Private Education Loans in forbearance, After Year 5</link:label>
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    <link:label id="lab_slm_OffBalanceSheetCreditLossLiabilityWriteoff_a28bbeb2-1c33-4e3e-bac8-ed1b6b7427cd_negatedLabel_en-US" xlink:label="lab_slm_OffBalanceSheetCreditLossLiabilityWriteoff" xlink:role="http://www.xbrl.org/2009/role/negatedLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Transfer - funded loans</link:label>
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    <link:label id="lab_slm_OffBalanceSheetCreditLossLiabilityWriteoff_documentation_en-US" xlink:label="lab_slm_OffBalanceSheetCreditLossLiabilityWriteoff" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Off-Balance Sheet, Credit Loss, Liability, Writeoff</link:label>
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    <link:label id="lab_slm_LoansOriginatedTwoYearsBeforeCurrentFiscalYear_bcafd75b-1b04-469f-8a1e-728be25b476e_terseLabel_en-US" xlink:label="lab_slm_LoansOriginatedTwoYearsBeforeCurrentFiscalYear" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Total Private Education Loans, Year 3</link:label>
    <link:label id="lab_slm_LoansOriginatedTwoYearsBeforeCurrentFiscalYear_label_en-US" xlink:label="lab_slm_LoansOriginatedTwoYearsBeforeCurrentFiscalYear" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Loans, Originated Two Years Before Current Fiscal Year</link:label>
    <link:label id="lab_slm_LoansOriginatedTwoYearsBeforeCurrentFiscalYear_documentation_en-US" xlink:label="lab_slm_LoansOriginatedTwoYearsBeforeCurrentFiscalYear" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Loans, Originated Two Years Before Current Fiscal Year</link:label>
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    <link:label id="lab_slm_PercentageOfLoansInRepaymentOriginatedInCurrentFiscalYear_4c4b62c6-726d-41b6-b187-7ebffa419362_terseLabel_en-US" xlink:label="lab_slm_PercentageOfLoansInRepaymentOriginatedInCurrentFiscalYear" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Percentage of Private Education Loans in repayment, Year 1</link:label>
    <link:label id="lab_slm_PercentageOfLoansInRepaymentOriginatedInCurrentFiscalYear_label_en-US" xlink:label="lab_slm_PercentageOfLoansInRepaymentOriginatedInCurrentFiscalYear" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Percentage Of Loans In Repayment, Originated In Current Fiscal Year</link:label>
    <link:label id="lab_slm_PercentageOfLoansInRepaymentOriginatedInCurrentFiscalYear_documentation_en-US" xlink:label="lab_slm_PercentageOfLoansInRepaymentOriginatedInCurrentFiscalYear" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Percentage Of Loans In Repayment, Originated In Current Fiscal Year</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_slm_PercentageOfLoansInRepaymentOriginatedInCurrentFiscalYear" xlink:href="slm-20230331.xsd#slm_PercentageOfLoansInRepaymentOriginatedInCurrentFiscalYear"/>
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    <link:label id="lab_us-gaap_FinancingReceivableExcludingAccruedInterestAllowanceForCreditLossWriteoffAfterRecovery_0271f0ec-e67c-465d-9313-c1504d4dec4e_negatedTerseLabel_en-US" xlink:label="lab_us-gaap_FinancingReceivableExcludingAccruedInterestAllowanceForCreditLossWriteoffAfterRecovery" xlink:role="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Net charge-offs</link:label>
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    <link:label id="lab_us-gaap_NetCashProvidedByUsedInInvestingActivities_99d29288-9b8a-4237-b1b4-4bb85501fae2_totalLabel_en-US" xlink:label="lab_us-gaap_NetCashProvidedByUsedInInvestingActivities" xlink:role="http://www.xbrl.org/2003/role/totalLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Total net cash used in investing activities</link:label>
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    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_NetCashProvidedByUsedInInvestingActivities"/>
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    <link:label id="lab_us-gaap_DebtInstrumentFaceAmount_556f91e5-6dba-477d-8fe3-27511faa9a7c_terseLabel_en-US" xlink:label="lab_us-gaap_DebtInstrumentFaceAmount" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Total Issued</link:label>
    <link:label id="lab_us-gaap_DebtInstrumentFaceAmount_label_en-US" xlink:label="lab_us-gaap_DebtInstrumentFaceAmount" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Debt Instrument, Face Amount</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentFaceAmount" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_DebtInstrumentFaceAmount"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_DebtInstrumentFaceAmount" xlink:to="lab_us-gaap_DebtInstrumentFaceAmount" xlink:type="arc" order="1"/>
    <link:label id="lab_slm_NetIncreaseDecreaseinUpfrontLoanFees_3c89e01d-03d0-47db-93f1-300039ca6709_terseLabel_en-US" xlink:label="lab_slm_NetIncreaseDecreaseinUpfrontLoanFees" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Fees paid on Secured Borrowing Facility</link:label>
    <link:label id="lab_slm_NetIncreaseDecreaseinUpfrontLoanFees_label_en-US" xlink:label="lab_slm_NetIncreaseDecreaseinUpfrontLoanFees" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Net Increase (Decrease) in Upfront Loan Fees</link:label>
    <link:label id="lab_slm_NetIncreaseDecreaseinUpfrontLoanFees_documentation_en-US" xlink:label="lab_slm_NetIncreaseDecreaseinUpfrontLoanFees" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Net Increase (Decrease) in Upfront Loan Fees</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_slm_NetIncreaseDecreaseinUpfrontLoanFees" xlink:href="slm-20230331.xsd#slm_NetIncreaseDecreaseinUpfrontLoanFees"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_slm_NetIncreaseDecreaseinUpfrontLoanFees" xlink:to="lab_slm_NetIncreaseDecreaseinUpfrontLoanFees" xlink:type="arc" order="1"/>
    <link:label id="lab_slm_LoansGrossOriginatedFourYearsBeforeLatestFiscalYear_97c8509e-ecd6-4d31-8072-b9a59500c94e_terseLabel_en-US" xlink:label="lab_slm_LoansGrossOriginatedFourYearsBeforeLatestFiscalYear" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Total Private Education Loans, gross, Year 5</link:label>
    <link:label id="lab_slm_LoansGrossOriginatedFourYearsBeforeLatestFiscalYear_label_en-US" xlink:label="lab_slm_LoansGrossOriginatedFourYearsBeforeLatestFiscalYear" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Loans Gross, Originated Four Years Before Latest Fiscal Year</link:label>
    <link:label id="lab_slm_LoansGrossOriginatedFourYearsBeforeLatestFiscalYear_documentation_en-US" xlink:label="lab_slm_LoansGrossOriginatedFourYearsBeforeLatestFiscalYear" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Loans Gross, Originated Four Years Before Latest Fiscal Year</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_slm_LoansGrossOriginatedFourYearsBeforeLatestFiscalYear" xlink:href="slm-20230331.xsd#slm_LoansGrossOriginatedFourYearsBeforeLatestFiscalYear"/>
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    <link:label id="lab_dei_EntityCurrentReportingStatus_ef48e4a1-1b68-4c69-a080-af0ca2d1f37d_terseLabel_en-US" xlink:label="lab_dei_EntityCurrentReportingStatus" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Entity Current Reporting Status</link:label>
    <link:label id="lab_dei_EntityCurrentReportingStatus_label_en-US" xlink:label="lab_dei_EntityCurrentReportingStatus" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Entity Current Reporting Status</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityCurrentReportingStatus" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_EntityCurrentReportingStatus"/>
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    <link:label id="lab_us-gaap_TierOneLeverageCapitalRequiredToBeWellCapitalizedToAverageAssets_c956b7bd-da66-4660-bb40-47f892f0ef38_terseLabel_en-US" xlink:label="lab_us-gaap_TierOneLeverageCapitalRequiredToBeWellCapitalizedToAverageAssets" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Tier 1 Capital (to Average Assets)</link:label>
    <link:label id="lab_us-gaap_TierOneLeverageCapitalRequiredToBeWellCapitalizedToAverageAssets_label_en-US" xlink:label="lab_us-gaap_TierOneLeverageCapitalRequiredToBeWellCapitalizedToAverageAssets" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Banking Regulation, Tier 1 Leverage Capital Ratio, Well Capitalized, Minimum</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_TierOneLeverageCapitalRequiredToBeWellCapitalizedToAverageAssets" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_TierOneLeverageCapitalRequiredToBeWellCapitalizedToAverageAssets"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_TierOneLeverageCapitalRequiredToBeWellCapitalizedToAverageAssets" xlink:to="lab_us-gaap_TierOneLeverageCapitalRequiredToBeWellCapitalizedToAverageAssets" xlink:type="arc" order="1"/>
    <link:label id="lab_slm_FinancingReceivableAllowanceForCreditLossOriginatedFourYearsBeforeCurrentFiscalYear_c769255d-9aad-42ee-8c3a-39be25ba0a70_negatedTerseLabel_en-US" xlink:label="lab_slm_FinancingReceivableAllowanceForCreditLossOriginatedFourYearsBeforeCurrentFiscalYear" xlink:role="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Private Education Loans allowance for losses, Year 5</link:label>
    <link:label id="lab_slm_FinancingReceivableAllowanceForCreditLossOriginatedFourYearsBeforeCurrentFiscalYear_label_en-US" xlink:label="lab_slm_FinancingReceivableAllowanceForCreditLossOriginatedFourYearsBeforeCurrentFiscalYear" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Financing Receivable, Allowance For Credit Loss, Originated Four Years Before Current Fiscal Year</link:label>
    <link:label id="lab_slm_FinancingReceivableAllowanceForCreditLossOriginatedFourYearsBeforeCurrentFiscalYear_documentation_en-US" xlink:label="lab_slm_FinancingReceivableAllowanceForCreditLossOriginatedFourYearsBeforeCurrentFiscalYear" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Financing Receivable, Allowance For Credit Loss, Originated Four Years Before Current Fiscal Year</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_slm_FinancingReceivableAllowanceForCreditLossOriginatedFourYearsBeforeCurrentFiscalYear" xlink:href="slm-20230331.xsd#slm_FinancingReceivableAllowanceForCreditLossOriginatedFourYearsBeforeCurrentFiscalYear"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_slm_FinancingReceivableAllowanceForCreditLossOriginatedFourYearsBeforeCurrentFiscalYear" xlink:to="lab_slm_FinancingReceivableAllowanceForCreditLossOriginatedFourYearsBeforeCurrentFiscalYear" xlink:type="arc" order="1"/>
    <link:label id="lab_slm_DelinquenciesAsPercentageOfLoansInRepaymentOriginatedThreeYearsBeforeCurrentFiscalYear_4704f706-5fef-4384-9030-cea6f469fd6e_terseLabel_en-US" xlink:label="lab_slm_DelinquenciesAsPercentageOfLoansInRepaymentOriginatedThreeYearsBeforeCurrentFiscalYear" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Delinquent Private Education Loans in repayment as a percentage of Private Education Loans in repayment, Year 4</link:label>
    <link:label id="lab_slm_DelinquenciesAsPercentageOfLoansInRepaymentOriginatedThreeYearsBeforeCurrentFiscalYear_label_en-US" xlink:label="lab_slm_DelinquenciesAsPercentageOfLoansInRepaymentOriginatedThreeYearsBeforeCurrentFiscalYear" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Delinquencies As Percentage Of Loans In Repayment, Originated Three Years Before Current Fiscal Year</link:label>
    <link:label id="lab_slm_DelinquenciesAsPercentageOfLoansInRepaymentOriginatedThreeYearsBeforeCurrentFiscalYear_documentation_en-US" xlink:label="lab_slm_DelinquenciesAsPercentageOfLoansInRepaymentOriginatedThreeYearsBeforeCurrentFiscalYear" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Delinquencies As Percentage Of Loans In Repayment, Originated Three Years Before Current Fiscal Year</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_slm_DelinquenciesAsPercentageOfLoansInRepaymentOriginatedThreeYearsBeforeCurrentFiscalYear" xlink:href="slm-20230331.xsd#slm_DelinquenciesAsPercentageOfLoansInRepaymentOriginatedThreeYearsBeforeCurrentFiscalYear"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_slm_DelinquenciesAsPercentageOfLoansInRepaymentOriginatedThreeYearsBeforeCurrentFiscalYear" xlink:to="lab_slm_DelinquenciesAsPercentageOfLoansInRepaymentOriginatedThreeYearsBeforeCurrentFiscalYear" xlink:type="arc" order="1"/>
    <link:label id="lab_slm_FixedPayLoanMonthlyPaymentAmountBelowMonthlyAccruedInterest_63647c62-9f83-438a-b8b5-a4e202ec96eb_terseLabel_en-US" xlink:label="lab_slm_FixedPayLoanMonthlyPaymentAmountBelowMonthlyAccruedInterest" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Monthly payment that is smaller than the interest accrued on the loan in that month</link:label>
    <link:label id="lab_slm_FixedPayLoanMonthlyPaymentAmountBelowMonthlyAccruedInterest_label_en-US" xlink:label="lab_slm_FixedPayLoanMonthlyPaymentAmountBelowMonthlyAccruedInterest" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Fixed-Pay Loan, Monthly Payment Amount, Below Monthly Accrued Interest</link:label>
    <link:label id="lab_slm_FixedPayLoanMonthlyPaymentAmountBelowMonthlyAccruedInterest_documentation_en-US" xlink:label="lab_slm_FixedPayLoanMonthlyPaymentAmountBelowMonthlyAccruedInterest" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Fixed-Pay Loan, Monthly Payment Amount, Below Monthly Accrued Interest</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_slm_FixedPayLoanMonthlyPaymentAmountBelowMonthlyAccruedInterest" xlink:href="slm-20230331.xsd#slm_FixedPayLoanMonthlyPaymentAmountBelowMonthlyAccruedInterest"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_slm_FixedPayLoanMonthlyPaymentAmountBelowMonthlyAccruedInterest" xlink:to="lab_slm_FixedPayLoanMonthlyPaymentAmountBelowMonthlyAccruedInterest" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_DebtSecuritiesAvailableForSaleUnrealizedGainLoss_33e345a7-b904-490f-9741-c3fd795e1466_negatedTerseLabel_en-US" xlink:label="lab_us-gaap_DebtSecuritiesAvailableForSaleUnrealizedGainLoss" xlink:role="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Unrealized loss</link:label>
    <link:label id="lab_us-gaap_DebtSecuritiesAvailableForSaleUnrealizedGainLoss_label_en-US" xlink:label="lab_us-gaap_DebtSecuritiesAvailableForSaleUnrealizedGainLoss" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Debt Securities, Available-for-Sale, Unrealized Gain (Loss)</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtSecuritiesAvailableForSaleUnrealizedGainLoss" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_DebtSecuritiesAvailableForSaleUnrealizedGainLoss"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_DebtSecuritiesAvailableForSaleUnrealizedGainLoss" xlink:to="lab_us-gaap_DebtSecuritiesAvailableForSaleUnrealizedGainLoss" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_InterestAndDividendIncomeOperating_ed35e66d-a73b-4cba-97c7-133519cb25ee_totalLabel_en-US" xlink:label="lab_us-gaap_InterestAndDividendIncomeOperating" xlink:role="http://www.xbrl.org/2003/role/totalLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Total interest income</link:label>
    <link:label id="lab_us-gaap_InterestAndDividendIncomeOperating_label_en-US" xlink:label="lab_us-gaap_InterestAndDividendIncomeOperating" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Interest and Dividend Income, Operating</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestAndDividendIncomeOperating" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_InterestAndDividendIncomeOperating"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_InterestAndDividendIncomeOperating" xlink:to="lab_us-gaap_InterestAndDividendIncomeOperating" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_DerivativeTable_2acf1b0b-7a52-4e55-a308-d7a3c96b4e0a_terseLabel_en-US" xlink:label="lab_us-gaap_DerivativeTable" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Derivative [Table]</link:label>
    <link:label id="lab_us-gaap_DerivativeTable_label_en-US" xlink:label="lab_us-gaap_DerivativeTable" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Derivative [Table]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeTable" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_DerivativeTable"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_DerivativeTable" xlink:to="lab_us-gaap_DerivativeTable" xlink:type="arc" order="1"/>
    <link:label id="lab_slm_AccruedInterestReceivableExpectedToBeCapitalizedReservedAllowanceForCreditLosses_568b3988-05d1-4a05-a095-eca5c5e8d631_terseLabel_en-US" xlink:label="lab_slm_AccruedInterestReceivableExpectedToBeCapitalizedReservedAllowanceForCreditLosses" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Accrued interest receivable expected to be capitalized reserved</link:label>
    <link:label id="lab_slm_AccruedInterestReceivableExpectedToBeCapitalizedReservedAllowanceForCreditLosses_label_en-US" xlink:label="lab_slm_AccruedInterestReceivableExpectedToBeCapitalizedReservedAllowanceForCreditLosses" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Accrued Interest Receivable Expected To Be Capitalized Reserved Allowance For Credit Losses</link:label>
    <link:label id="lab_slm_AccruedInterestReceivableExpectedToBeCapitalizedReservedAllowanceForCreditLosses_documentation_en-US" xlink:label="lab_slm_AccruedInterestReceivableExpectedToBeCapitalizedReservedAllowanceForCreditLosses" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Accrued Interest Receivable Expected To Be Capitalized Reserved Allowance For Credit Losses</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_slm_AccruedInterestReceivableExpectedToBeCapitalizedReservedAllowanceForCreditLosses" xlink:href="slm-20230331.xsd#slm_AccruedInterestReceivableExpectedToBeCapitalizedReservedAllowanceForCreditLosses"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_slm_AccruedInterestReceivableExpectedToBeCapitalizedReservedAllowanceForCreditLosses" xlink:to="lab_slm_AccruedInterestReceivableExpectedToBeCapitalizedReservedAllowanceForCreditLosses" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_FinancingReceivables30To59DaysPastDueMember_85ce517e-aaff-480f-ae7a-28fefa048cb3_verboseLabel_en-US" xlink:label="lab_us-gaap_FinancingReceivables30To59DaysPastDueMember" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">30-59 Days Past Due</link:label>
    <link:label id="lab_us-gaap_FinancingReceivables30To59DaysPastDueMember_42ada0b7-fe84-4d01-a757-02cad6dcc673_terseLabel_en-US" xlink:label="lab_us-gaap_FinancingReceivables30To59DaysPastDueMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Loan delinquent 30-59 days</link:label>
    <link:label id="lab_us-gaap_FinancingReceivables30To59DaysPastDueMember_label_en-US" xlink:label="lab_us-gaap_FinancingReceivables30To59DaysPastDueMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Financial Asset, 30 to 59 Days Past Due [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinancingReceivables30To59DaysPastDueMember" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_FinancingReceivables30To59DaysPastDueMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_FinancingReceivables30To59DaysPastDueMember" xlink:to="lab_us-gaap_FinancingReceivables30To59DaysPastDueMember" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_ScheduleOfStockByClassTable_446888af-3655-4667-8d96-65293847658a_terseLabel_en-US" xlink:label="lab_us-gaap_ScheduleOfStockByClassTable" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Schedule of Stock by Class [Table]</link:label>
    <link:label id="lab_us-gaap_ScheduleOfStockByClassTable_label_en-US" xlink:label="lab_us-gaap_ScheduleOfStockByClassTable" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Schedule of Stock by Class [Table]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfStockByClassTable" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ScheduleOfStockByClassTable"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_ScheduleOfStockByClassTable" xlink:to="lab_us-gaap_ScheduleOfStockByClassTable" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_BasisOfAccountingPolicyPolicyTextBlock_4a76a392-ac8f-4cce-a3fc-f0709b3569a2_terseLabel_en-US" xlink:label="lab_us-gaap_BasisOfAccountingPolicyPolicyTextBlock" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Basis of Presentation</link:label>
    <link:label id="lab_us-gaap_BasisOfAccountingPolicyPolicyTextBlock_label_en-US" xlink:label="lab_us-gaap_BasisOfAccountingPolicyPolicyTextBlock" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Basis of Accounting, Policy [Policy Text Block]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BasisOfAccountingPolicyPolicyTextBlock" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_BasisOfAccountingPolicyPolicyTextBlock"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_BasisOfAccountingPolicyPolicyTextBlock" xlink:to="lab_us-gaap_BasisOfAccountingPolicyPolicyTextBlock" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_LiabilitiesAbstract_29f9ef11-56f5-46ad-aefa-278ed1f3e7e9_terseLabel_en-US" xlink:label="lab_us-gaap_LiabilitiesAbstract" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Liabilities</link:label>
    <link:label id="lab_us-gaap_LiabilitiesAbstract_label_en-US" xlink:label="lab_us-gaap_LiabilitiesAbstract" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Liabilities [Abstract]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LiabilitiesAbstract" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_LiabilitiesAbstract"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_LiabilitiesAbstract" xlink:to="lab_us-gaap_LiabilitiesAbstract" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_PropertyPlantAndEquipmentNet_ec678aff-1d11-434d-ab0a-680308966f97_terseLabel_en-US" xlink:label="lab_us-gaap_PropertyPlantAndEquipmentNet" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Premises and equipment, net</link:label>
    <link:label id="lab_us-gaap_PropertyPlantAndEquipmentNet_label_en-US" xlink:label="lab_us-gaap_PropertyPlantAndEquipmentNet" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Property, Plant and Equipment, Net</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentNet" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_PropertyPlantAndEquipmentNet"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentNet" xlink:to="lab_us-gaap_PropertyPlantAndEquipmentNet" xlink:type="arc" order="1"/>
    <link:label id="lab_slm_Lendablevalueofcollateral_a56e226c-a0a7-41b5-b2e0-13868f6c6de3_terseLabel_en-US" xlink:label="lab_slm_Lendablevalueofcollateral" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Lendable value of collateral</link:label>
    <link:label id="lab_slm_Lendablevalueofcollateral_label_en-US" xlink:label="lab_slm_Lendablevalueofcollateral" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Lendable value of collateral</link:label>
    <link:label id="lab_slm_Lendablevalueofcollateral_documentation_en-US" xlink:label="lab_slm_Lendablevalueofcollateral" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Lendable value of collateral</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_slm_Lendablevalueofcollateral" xlink:href="slm-20230331.xsd#slm_Lendablevalueofcollateral"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_slm_Lendablevalueofcollateral" xlink:to="lab_slm_Lendablevalueofcollateral" xlink:type="arc" order="1"/>
    <link:label id="lab_slm_CashAndInvestmentsInterestIncomeLoss_5cdf2235-6b11-431f-9204-2ad03c137b31_terseLabel_en-US" xlink:label="lab_slm_CashAndInvestmentsInterestIncomeLoss" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Cash and cash equivalents</link:label>
    <link:label id="lab_slm_CashAndInvestmentsInterestIncomeLoss_label_en-US" xlink:label="lab_slm_CashAndInvestmentsInterestIncomeLoss" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Cash And Investments Interest Income Loss</link:label>
    <link:label id="lab_slm_CashAndInvestmentsInterestIncomeLoss_documentation_en-US" xlink:label="lab_slm_CashAndInvestmentsInterestIncomeLoss" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Cash and investments interest income (loss).</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_slm_CashAndInvestmentsInterestIncomeLoss" xlink:href="slm-20230331.xsd#slm_CashAndInvestmentsInterestIncomeLoss"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_slm_CashAndInvestmentsInterestIncomeLoss" xlink:to="lab_slm_CashAndInvestmentsInterestIncomeLoss" xlink:type="arc" order="1"/>
    <link:label id="lab_dei_EntitiesTable_cc09a022-d2e6-4130-af38-8d434118c719_terseLabel_en-US" xlink:label="lab_dei_EntitiesTable" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Entities [Table]</link:label>
    <link:label id="lab_dei_EntitiesTable_label_en-US" xlink:label="lab_dei_EntitiesTable" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Entities [Table]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntitiesTable" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_EntitiesTable"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_dei_EntitiesTable" xlink:to="lab_dei_EntitiesTable" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_ProceedsFromIncomeTaxRefunds_85aecfff-682d-47a4-9ff6-e5f358dc8d95_negatedTerseLabel_en-US" xlink:label="lab_us-gaap_ProceedsFromIncomeTaxRefunds" xlink:role="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Income taxes refunded</link:label>
    <link:label id="lab_us-gaap_ProceedsFromIncomeTaxRefunds_label_en-US" xlink:label="lab_us-gaap_ProceedsFromIncomeTaxRefunds" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Proceeds from Income Tax Refunds</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProceedsFromIncomeTaxRefunds" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ProceedsFromIncomeTaxRefunds"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_ProceedsFromIncomeTaxRefunds" xlink:to="lab_us-gaap_ProceedsFromIncomeTaxRefunds" xlink:type="arc" order="1"/>
    <link:label id="lab_slm_LossContingencyLossEmergencePeriod_025edab4-cb9b-4e42-a10e-c74987c995d0_terseLabel_en-US" xlink:label="lab_slm_LossContingencyLossEmergencePeriod" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Loss emergence period</link:label>
    <link:label id="lab_slm_LossContingencyLossEmergencePeriod_label_en-US" xlink:label="lab_slm_LossContingencyLossEmergencePeriod" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Loss Contingency, Loss Emergence Period</link:label>
    <link:label id="lab_slm_LossContingencyLossEmergencePeriod_documentation_en-US" xlink:label="lab_slm_LossContingencyLossEmergencePeriod" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Loss Contingency, Loss Emergence Period</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_slm_LossContingencyLossEmergencePeriod" xlink:href="slm-20230331.xsd#slm_LossContingencyLossEmergencePeriod"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_slm_LossContingencyLossEmergencePeriod" xlink:to="lab_slm_LossContingencyLossEmergencePeriod" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_TransfersAndServicingAbstract_label_en-US" xlink:label="lab_us-gaap_TransfersAndServicingAbstract" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Transfers and Servicing [Abstract]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_TransfersAndServicingAbstract" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_TransfersAndServicingAbstract"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_TransfersAndServicingAbstract" xlink:to="lab_us-gaap_TransfersAndServicingAbstract" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_Dividends_63f8af25-2192-4de0-8599-808388931e5c_terseLabel_en-US" xlink:label="lab_us-gaap_Dividends" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Dividends</link:label>
    <link:label id="lab_us-gaap_Dividends_label_en-US" xlink:label="lab_us-gaap_Dividends" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Dividends</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_Dividends" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_Dividends"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_Dividends" xlink:to="lab_us-gaap_Dividends" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_EffectOfCashFlowHedgesOnResultsOfOperationsAbstract_1e2042a4-ca17-4ad1-88dc-9fcc1a0f6bfb_terseLabel_en-US" xlink:label="lab_us-gaap_EffectOfCashFlowHedgesOnResultsOfOperationsAbstract" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Cash Flow Hedges</link:label>
    <link:label id="lab_us-gaap_EffectOfCashFlowHedgesOnResultsOfOperationsAbstract_label_en-US" xlink:label="lab_us-gaap_EffectOfCashFlowHedgesOnResultsOfOperationsAbstract" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Effect of Cash Flow Hedges on Results of Operations [Abstract]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EffectOfCashFlowHedgesOnResultsOfOperationsAbstract" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_EffectOfCashFlowHedgesOnResultsOfOperationsAbstract"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_EffectOfCashFlowHedgesOnResultsOfOperationsAbstract" xlink:to="lab_us-gaap_EffectOfCashFlowHedgesOnResultsOfOperationsAbstract" xlink:type="arc" order="1"/>
    <link:label id="lab_slm_FinancingReceivablePeriodOfInterestRateReductionFinancialDifficultyStatus_16264224-abe7-4421-9fae-dafe56e4acfd_terseLabel_en-US" xlink:label="lab_slm_FinancingReceivablePeriodOfInterestRateReductionFinancialDifficultyStatus" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Interest rate offered to borrowers facing financial difficulty, period</link:label>
    <link:label id="lab_slm_FinancingReceivablePeriodOfInterestRateReductionFinancialDifficultyStatus_label_en-US" xlink:label="lab_slm_FinancingReceivablePeriodOfInterestRateReductionFinancialDifficultyStatus" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Financing Receivable, Period Of Interest Rate Reduction, Financial Difficulty Status</link:label>
    <link:label id="lab_slm_FinancingReceivablePeriodOfInterestRateReductionFinancialDifficultyStatus_documentation_en-US" xlink:label="lab_slm_FinancingReceivablePeriodOfInterestRateReductionFinancialDifficultyStatus" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Financing Receivable, Period Of Interest Rate Reduction, Financial Difficulty Status</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_slm_FinancingReceivablePeriodOfInterestRateReductionFinancialDifficultyStatus" xlink:href="slm-20230331.xsd#slm_FinancingReceivablePeriodOfInterestRateReductionFinancialDifficultyStatus"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_slm_FinancingReceivablePeriodOfInterestRateReductionFinancialDifficultyStatus" xlink:to="lab_slm_FinancingReceivablePeriodOfInterestRateReductionFinancialDifficultyStatus" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_LongTermDebt_03a85b1c-64c2-4bbc-887f-1b2640d45754_terseLabel_en-US" xlink:label="lab_us-gaap_LongTermDebt" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Long-term borrowings</link:label>
    <link:label id="lab_us-gaap_LongTermDebt_6f70d3b3-4ea1-4a40-9416-b359b2ce5e06_verboseLabel_en-US" xlink:label="lab_us-gaap_LongTermDebt" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Long-Term</link:label>
    <link:label id="lab_us-gaap_LongTermDebt_label_en-US" xlink:label="lab_us-gaap_LongTermDebt" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Long-Term Debt</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongTermDebt" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_LongTermDebt"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_LongTermDebt" xlink:to="lab_us-gaap_LongTermDebt" xlink:type="arc" order="1"/>
    <link:label id="lab_slm_NetUnamortizedPremiumOrDiscountOriginatedFourYearsBeforeCurrentFiscalYear_59947087-d0bd-4996-ac21-bc20cd25271b_terseLabel_en-US" xlink:label="lab_slm_NetUnamortizedPremiumOrDiscountOriginatedFourYearsBeforeCurrentFiscalYear" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Private Education Loans deferred origination costs and unamortized premium/(discount), Year 5</link:label>
    <link:label id="lab_slm_NetUnamortizedPremiumOrDiscountOriginatedFourYearsBeforeCurrentFiscalYear_label_en-US" xlink:label="lab_slm_NetUnamortizedPremiumOrDiscountOriginatedFourYearsBeforeCurrentFiscalYear" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Net Unamortized Premium Or Discount, Originated Four Years Before Current Fiscal Year</link:label>
    <link:label id="lab_slm_NetUnamortizedPremiumOrDiscountOriginatedFourYearsBeforeCurrentFiscalYear_documentation_en-US" xlink:label="lab_slm_NetUnamortizedPremiumOrDiscountOriginatedFourYearsBeforeCurrentFiscalYear" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Net Unamortized Premium Or Discount, Originated Four Years Before Current Fiscal Year</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_slm_NetUnamortizedPremiumOrDiscountOriginatedFourYearsBeforeCurrentFiscalYear" xlink:href="slm-20230331.xsd#slm_NetUnamortizedPremiumOrDiscountOriginatedFourYearsBeforeCurrentFiscalYear"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_slm_NetUnamortizedPremiumOrDiscountOriginatedFourYearsBeforeCurrentFiscalYear" xlink:to="lab_slm_NetUnamortizedPremiumOrDiscountOriginatedFourYearsBeforeCurrentFiscalYear" xlink:type="arc" order="1"/>
    <link:label id="lab_slm_LongtermDebtFairValueDifferenceBetweenCarryingValueandFairValue_828ce3b8-0bc6-4531-ba6d-a69f5b4db2c1_terseLabel_en-US" xlink:label="lab_slm_LongtermDebtFairValueDifferenceBetweenCarryingValueandFairValue" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Long-term borrowings, difference</link:label>
    <link:label id="lab_slm_LongtermDebtFairValueDifferenceBetweenCarryingValueandFairValue_label_en-US" xlink:label="lab_slm_LongtermDebtFairValueDifferenceBetweenCarryingValueandFairValue" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Long-term Debt, Fair Value, Difference Between Carrying Value and Fair Value</link:label>
    <link:label id="lab_slm_LongtermDebtFairValueDifferenceBetweenCarryingValueandFairValue_documentation_en-US" xlink:label="lab_slm_LongtermDebtFairValueDifferenceBetweenCarryingValueandFairValue" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Long-term Debt, Fair Value, Difference Between Carrying Value and Fair Value</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_slm_LongtermDebtFairValueDifferenceBetweenCarryingValueandFairValue" xlink:href="slm-20230331.xsd#slm_LongtermDebtFairValueDifferenceBetweenCarryingValueandFairValue"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_slm_LongtermDebtFairValueDifferenceBetweenCarryingValueandFairValue" xlink:to="lab_slm_LongtermDebtFairValueDifferenceBetweenCarryingValueandFairValue" xlink:type="arc" order="1"/>
    <link:label id="lab_slm_LoansPledgedAsCollateralCapitalizedInterest_ffa6819b-02da-4a8a-99c3-aa1a05a8f380_terseLabel_en-US" xlink:label="lab_slm_LoansPledgedAsCollateralCapitalizedInterest" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Capitalized interest</link:label>
    <link:label id="lab_slm_LoansPledgedAsCollateralCapitalizedInterest_label_en-US" xlink:label="lab_slm_LoansPledgedAsCollateralCapitalizedInterest" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Loans Pledged As Collateral, Capitalized Interest</link:label>
    <link:label id="lab_slm_LoansPledgedAsCollateralCapitalizedInterest_documentation_en-US" xlink:label="lab_slm_LoansPledgedAsCollateralCapitalizedInterest" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Loans Pledged As Collateral, Capitalized Interest</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_slm_LoansPledgedAsCollateralCapitalizedInterest" xlink:href="slm-20230331.xsd#slm_LoansPledgedAsCollateralCapitalizedInterest"/>
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    <link:label id="lab_us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTax_c9bb1574-cdbe-474c-b8ff-602a6a5ac6eb_terseLabel_en-US" xlink:label="lab_us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTax" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Accumulated other comprehensive loss (net of tax benefit of ($25,139) and ($30,160), respectively)</link:label>
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    <link:label id="lab_slm_AmortizationofBrokeredDepositPlacement_documentation_en-US" xlink:label="lab_slm_AmortizationofBrokeredDepositPlacement" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">amortization of brokered deposit placement</link:label>
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    <link:label id="lab_us-gaap_RegulatoryCapitalRequirementsUnderBankingRegulationsTextBlock_1e6c0177-b3ad-4de3-a494-851054500691_terseLabel_en-US" xlink:label="lab_us-gaap_RegulatoryCapitalRequirementsUnderBankingRegulationsTextBlock" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Regulatory Capital</link:label>
    <link:label id="lab_us-gaap_RegulatoryCapitalRequirementsUnderBankingRegulationsTextBlock_label_en-US" xlink:label="lab_us-gaap_RegulatoryCapitalRequirementsUnderBankingRegulationsTextBlock" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Regulatory Capital Requirements under Banking Regulations [Text Block]</link:label>
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    <link:label id="lab_slm_LoansInForbearanceAsAPercentageOfPrivateEducationLoansInRepaymentAndForbearanceOriginatedInFiscalYearBeforeLatestFiscalYear_label_en-US" xlink:label="lab_slm_LoansInForbearanceAsAPercentageOfPrivateEducationLoansInRepaymentAndForbearanceOriginatedInFiscalYearBeforeLatestFiscalYear" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Loans In Forbearance As A Percentage Of Private Education Loans In repayment And Forbearance, Originated In Fiscal Year Before Latest Fiscal Year</link:label>
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    <link:label id="lab_dei_EntitySmallBusiness_10e48da9-173e-4dab-a467-6b16bae3f380_terseLabel_en-US" xlink:label="lab_dei_EntitySmallBusiness" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Entity Small Business</link:label>
    <link:label id="lab_dei_EntitySmallBusiness_label_en-US" xlink:label="lab_dei_EntitySmallBusiness" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Entity Small Business</link:label>
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    <link:label id="lab_us-gaap_FairValueByMeasurementBasisAxis_3f89de7e-720e-4c6e-9442-29965c00730f_terseLabel_en-US" xlink:label="lab_us-gaap_FairValueByMeasurementBasisAxis" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Measurement Basis [Axis]</link:label>
    <link:label id="lab_us-gaap_FairValueByMeasurementBasisAxis_label_en-US" xlink:label="lab_us-gaap_FairValueByMeasurementBasisAxis" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Measurement Basis [Axis]</link:label>
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    <link:label id="lab_us-gaap_CommonStockDividendsPerShareDeclared_5daf831d-0020-4da9-847b-c925eafb9ab4_verboseLabel_en-US" xlink:label="lab_us-gaap_CommonStockDividendsPerShareDeclared" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Declared dividends per common share (in dollars per share)</link:label>
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    <link:label id="lab_slm_LoansInForbearanceAsAPercentageOfPrivateEducationLoansInRepaymentAndForbearanceOriginatedFourYearsBeforeCurrentFiscalYear_1230e275-7e2b-403c-8ebe-21a5531eabc8_terseLabel_en-US" xlink:label="lab_slm_LoansInForbearanceAsAPercentageOfPrivateEducationLoansInRepaymentAndForbearanceOriginatedFourYearsBeforeCurrentFiscalYear" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Loans in forbearance as a percentage of loans in repayment and forbearance, Year 5</link:label>
    <link:label id="lab_slm_LoansInForbearanceAsAPercentageOfPrivateEducationLoansInRepaymentAndForbearanceOriginatedFourYearsBeforeCurrentFiscalYear_label_en-US" xlink:label="lab_slm_LoansInForbearanceAsAPercentageOfPrivateEducationLoansInRepaymentAndForbearanceOriginatedFourYearsBeforeCurrentFiscalYear" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Loans In Forbearance As A Percentage Of Private Education Loans In repayment And Forbearance, Originated Four Years Before Current Fiscal Year</link:label>
    <link:label id="lab_slm_LoansInForbearanceAsAPercentageOfPrivateEducationLoansInRepaymentAndForbearanceOriginatedFourYearsBeforeCurrentFiscalYear_documentation_en-US" xlink:label="lab_slm_LoansInForbearanceAsAPercentageOfPrivateEducationLoansInRepaymentAndForbearanceOriginatedFourYearsBeforeCurrentFiscalYear" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Loans In Forbearance As A Percentage Of Private Education Loans In repayment And Forbearance, Originated Four Years Before Current Fiscal Year</link:label>
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    <link:label id="lab_slm_BorrowingsCollateralizedByLoansInTrustIssued_7964bdc4-0a1b-4182-ad84-41ccc9af8710_terseLabel_en-US" xlink:label="lab_slm_BorrowingsCollateralizedByLoansInTrustIssued" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Borrowings collateralized by loans in securitization trusts - issued</link:label>
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    <link:label id="lab_slm_BorrowingsCollateralizedByLoansInTrustIssued_documentation_en-US" xlink:label="lab_slm_BorrowingsCollateralizedByLoansInTrustIssued" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Borrowings Collateralized By Loans In Trust Issued</link:label>
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    <link:label id="lab_srt_ConsolidatedEntitiesAxis_89fa46e2-0530-44b5-ab15-a3dbd75614d5_terseLabel_en-US" xlink:label="lab_srt_ConsolidatedEntitiesAxis" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Consolidated Entities [Axis]</link:label>
    <link:label id="lab_srt_ConsolidatedEntitiesAxis_label_en-US" xlink:label="lab_srt_ConsolidatedEntitiesAxis" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Consolidated Entities [Axis]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_srt_ConsolidatedEntitiesAxis" xlink:href="https://xbrl.fasb.org/srt/2022/elts/srt-2022.xsd#srt_ConsolidatedEntitiesAxis"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_srt_ConsolidatedEntitiesAxis" xlink:to="lab_srt_ConsolidatedEntitiesAxis" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_PrincipalAmountOutstandingOnLoansHeldForSaleOrSecuritization_165189ed-80ac-4a88-a730-c255d41ea376_terseLabel_en-US" xlink:label="lab_us-gaap_PrincipalAmountOutstandingOnLoansHeldForSaleOrSecuritization" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Private education loan term accounted for as a secured financing</link:label>
    <link:label id="lab_us-gaap_PrincipalAmountOutstandingOnLoansHeldForSaleOrSecuritization_label_en-US" xlink:label="lab_us-gaap_PrincipalAmountOutstandingOnLoansHeldForSaleOrSecuritization" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Principal Amount Outstanding on Loans Held-for-sale or Securitization or Asset-Backed Financing Arrangement</link:label>
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    <link:label id="lab_slm_LondonClearingHouseMember_336522f4-772f-4d0e-95a7-15193290d846_terseLabel_en-US" xlink:label="lab_slm_LondonClearingHouseMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">LCH</link:label>
    <link:label id="lab_slm_LondonClearingHouseMember_label_en-US" xlink:label="lab_slm_LondonClearingHouseMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">London Clearing House [Member]</link:label>
    <link:label id="lab_slm_LondonClearingHouseMember_documentation_en-US" xlink:label="lab_slm_LondonClearingHouseMember" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">London Clearing House [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_slm_LondonClearingHouseMember" xlink:href="slm-20230331.xsd#slm_LondonClearingHouseMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_slm_LondonClearingHouseMember" xlink:to="lab_slm_LondonClearingHouseMember" xlink:type="arc" order="1"/>
    <link:label id="lab_slm_AllowanceAsPercentageOfEndingLoansInRepayment_3a15572e-c5e5-47f1-bd0e-6448f7a2a25d_terseLabel_en-US" xlink:label="lab_slm_AllowanceAsPercentageOfEndingLoansInRepayment" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Allowance as a percentage of the ending loans in repayment and accrued interest to be capitalized on loans in repayment</link:label>
    <link:label id="lab_slm_AllowanceAsPercentageOfEndingLoansInRepayment_label_en-US" xlink:label="lab_slm_AllowanceAsPercentageOfEndingLoansInRepayment" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Allowance As Percentage Of Ending Loans In Repayment</link:label>
    <link:label id="lab_slm_AllowanceAsPercentageOfEndingLoansInRepayment_documentation_en-US" xlink:label="lab_slm_AllowanceAsPercentageOfEndingLoansInRepayment" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Allowance as a percentage of the ending loans in repayment.</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_slm_AllowanceAsPercentageOfEndingLoansInRepayment" xlink:href="slm-20230331.xsd#slm_AllowanceAsPercentageOfEndingLoansInRepayment"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_slm_AllowanceAsPercentageOfEndingLoansInRepayment" xlink:to="lab_slm_AllowanceAsPercentageOfEndingLoansInRepayment" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_DebtInstrumentLineItems_aeda584a-5c0b-4711-a3ab-88c2cb18f302_terseLabel_en-US" xlink:label="lab_us-gaap_DebtInstrumentLineItems" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Debt Instrument [Line Items]</link:label>
    <link:label id="lab_us-gaap_DebtInstrumentLineItems_label_en-US" xlink:label="lab_us-gaap_DebtInstrumentLineItems" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Debt Instrument [Line Items]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentLineItems" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_DebtInstrumentLineItems"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_DebtInstrumentLineItems" xlink:to="lab_us-gaap_DebtInstrumentLineItems" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_ClassOfStockLineItems_36c49f05-0bba-4806-8d5e-8ad62759aded_terseLabel_en-US" xlink:label="lab_us-gaap_ClassOfStockLineItems" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Class of Stock [Line Items]</link:label>
    <link:label id="lab_us-gaap_ClassOfStockLineItems_label_en-US" xlink:label="lab_us-gaap_ClassOfStockLineItems" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Class of Stock [Line Items]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfStockLineItems" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ClassOfStockLineItems"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_ClassOfStockLineItems" xlink:to="lab_us-gaap_ClassOfStockLineItems" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_PaymentsOfDebtIssuanceCosts_7bb72c2f-c6d5-4a60-88ac-49451a33f0ef_negatedTerseLabel_en-US" xlink:label="lab_us-gaap_PaymentsOfDebtIssuanceCosts" xlink:role="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Issuance costs for unsecured debt offering</link:label>
    <link:label id="lab_us-gaap_PaymentsOfDebtIssuanceCosts_label_en-US" xlink:label="lab_us-gaap_PaymentsOfDebtIssuanceCosts" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Payments of Debt Issuance Costs</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsOfDebtIssuanceCosts" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_PaymentsOfDebtIssuanceCosts"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_PaymentsOfDebtIssuanceCosts" xlink:to="lab_us-gaap_PaymentsOfDebtIssuanceCosts" xlink:type="arc" order="1"/>
    <link:label id="lab_slm_Maturity2047Member_e53c56aa-3258-406f-90c2-b61636878b27_terseLabel_en-US" xlink:label="lab_slm_Maturity2047Member" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">2047</link:label>
    <link:label id="lab_slm_Maturity2047Member_label_en-US" xlink:label="lab_slm_Maturity2047Member" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Maturity 2047 [Member]</link:label>
    <link:label id="lab_slm_Maturity2047Member_documentation_en-US" xlink:label="lab_slm_Maturity2047Member" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Maturity 2047 [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_slm_Maturity2047Member" xlink:href="slm-20230331.xsd#slm_Maturity2047Member"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_slm_Maturity2047Member" xlink:to="lab_slm_Maturity2047Member" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_InvestmentsDebtAndEquitySecuritiesAbstract_2e90c5bf-f32e-429e-aabb-912084a569c9_terseLabel_en-US" xlink:label="lab_us-gaap_InvestmentsDebtAndEquitySecuritiesAbstract" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Investments, Debt and Equity Securities [Abstract]</link:label>
    <link:label id="lab_us-gaap_InvestmentsDebtAndEquitySecuritiesAbstract_label_en-US" xlink:label="lab_us-gaap_InvestmentsDebtAndEquitySecuritiesAbstract" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Investments, Debt and Equity Securities [Abstract]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InvestmentsDebtAndEquitySecuritiesAbstract" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_InvestmentsDebtAndEquitySecuritiesAbstract"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_InvestmentsDebtAndEquitySecuritiesAbstract" xlink:to="lab_us-gaap_InvestmentsDebtAndEquitySecuritiesAbstract" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_DerivativeGainLossOnDerivativeNet_10f16ca2-78a2-4518-8a5b-087ede672025_totalLabel_en-US" xlink:label="lab_us-gaap_DerivativeGainLossOnDerivativeNet" xlink:role="http://www.xbrl.org/2003/role/totalLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Total</link:label>
    <link:label id="lab_us-gaap_DerivativeGainLossOnDerivativeNet_label_en-US" xlink:label="lab_us-gaap_DerivativeGainLossOnDerivativeNet" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Derivative, Gain (Loss) on Derivative, Net</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeGainLossOnDerivativeNet" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_DerivativeGainLossOnDerivativeNet"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_DerivativeGainLossOnDerivativeNet" xlink:to="lab_us-gaap_DerivativeGainLossOnDerivativeNet" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearTwo_e2828b74-606a-4130-95aa-20e4b5bd1785_terseLabel_en-US" xlink:label="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearTwo" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Expected amortization of 2024</link:label>
    <link:label id="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearTwo_label_en-US" xlink:label="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearTwo" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Finite-Lived Intangible Asset, Expected Amortization, Year Two</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearTwo" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearTwo"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearTwo" xlink:to="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearTwo" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_AvailableForSaleDebtSecuritiesAmortizedCostBasis_1a3f9931-73e7-438d-9974-e0cb8b658600_verboseLabel_en-US" xlink:label="lab_us-gaap_AvailableForSaleDebtSecuritiesAmortizedCostBasis" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Available-for sale investments at fair value, cost</link:label>
    <link:label id="lab_us-gaap_AvailableForSaleDebtSecuritiesAmortizedCostBasis_44532a3e-a66c-4edb-a873-ceb5977a81d7_terseLabel_en-US" xlink:label="lab_us-gaap_AvailableForSaleDebtSecuritiesAmortizedCostBasis" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Amortized Cost</link:label>
    <link:label id="lab_us-gaap_AvailableForSaleDebtSecuritiesAmortizedCostBasis_label_en-US" xlink:label="lab_us-gaap_AvailableForSaleDebtSecuritiesAmortizedCostBasis" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Debt Securities, Available-for-Sale, Amortized Cost</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AvailableForSaleDebtSecuritiesAmortizedCostBasis" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AvailableForSaleDebtSecuritiesAmortizedCostBasis"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_AvailableForSaleDebtSecuritiesAmortizedCostBasis" xlink:to="lab_us-gaap_AvailableForSaleDebtSecuritiesAmortizedCostBasis" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_FinancingReceivableExcludingAccruedInterestAllowanceForCreditLossRecovery_29ef63a2-9d69-4b91-bc0b-fdb47529bf1c_terseLabel_en-US" xlink:label="lab_us-gaap_FinancingReceivableExcludingAccruedInterestAllowanceForCreditLossRecovery" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Recoveries</link:label>
    <link:label id="lab_us-gaap_FinancingReceivableExcludingAccruedInterestAllowanceForCreditLossRecovery_7b1fb122-f41a-49ca-bddc-a58fe97b18eb_totalLabel_en-US" xlink:label="lab_us-gaap_FinancingReceivableExcludingAccruedInterestAllowanceForCreditLossRecovery" xlink:role="http://www.xbrl.org/2003/role/totalLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Recoveries</link:label>
    <link:label id="lab_us-gaap_FinancingReceivableExcludingAccruedInterestAllowanceForCreditLossRecovery_label_en-US" xlink:label="lab_us-gaap_FinancingReceivableExcludingAccruedInterestAllowanceForCreditLossRecovery" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Financing Receivable, Excluding Accrued Interest, Allowance for Credit Loss, Recovery</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinancingReceivableExcludingAccruedInterestAllowanceForCreditLossRecovery" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_FinancingReceivableExcludingAccruedInterestAllowanceForCreditLossRecovery"/>
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    <link:label id="lab_slm_SeasoningBasedOnMonthlyScheduledPaymentsDueFromOneToTwelvePaymentsInPercent_4fa30c55-af51-4705-b17e-ec88983583aa_terseLabel_en-US" xlink:label="lab_slm_SeasoningBasedOnMonthlyScheduledPaymentsDueFromOneToTwelvePaymentsInPercent" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Seasoning based on monthly scheduled payments due from 1-12 payments</link:label>
    <link:label id="lab_slm_SeasoningBasedOnMonthlyScheduledPaymentsDueFromOneToTwelvePaymentsInPercent_label_en-US" xlink:label="lab_slm_SeasoningBasedOnMonthlyScheduledPaymentsDueFromOneToTwelvePaymentsInPercent" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Seasoning Based On Monthly Scheduled Payments Due From One To Twelve Payments In Percent</link:label>
    <link:label id="lab_slm_SeasoningBasedOnMonthlyScheduledPaymentsDueFromOneToTwelvePaymentsInPercent_documentation_en-US" xlink:label="lab_slm_SeasoningBasedOnMonthlyScheduledPaymentsDueFromOneToTwelvePaymentsInPercent" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Seasoning based on monthly scheduled payments due from one to twelve payments in percent.</link:label>
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    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_slm_SeasoningBasedOnMonthlyScheduledPaymentsDueFromOneToTwelvePaymentsInPercent" xlink:to="lab_slm_SeasoningBasedOnMonthlyScheduledPaymentsDueFromOneToTwelvePaymentsInPercent" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_PastDueFinancingReceivablesTableTextBlock_17139c3b-3469-498d-8177-e5b051ae98f4_terseLabel_en-US" xlink:label="lab_us-gaap_PastDueFinancingReceivablesTableTextBlock" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Age Analysis of Past Due Loans Delinquencies</link:label>
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    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PastDueFinancingReceivablesTableTextBlock" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_PastDueFinancingReceivablesTableTextBlock"/>
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    <link:label id="lab_us-gaap_IncreaseDecreaseInOtherOperatingAssets_32ed40e8-f2a4-43a4-936d-6cbd62766f95_negatedTerseLabel_en-US" xlink:label="lab_us-gaap_IncreaseDecreaseInOtherOperatingAssets" xlink:role="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Increase in other assets</link:label>
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    <link:label id="lab_us-gaap_HedgingRelationshipDomain_5dffc875-0988-405b-9e13-87f6f4b08c47_terseLabel_en-US" xlink:label="lab_us-gaap_HedgingRelationshipDomain" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Hedging Relationship [Domain]</link:label>
    <link:label id="lab_us-gaap_HedgingRelationshipDomain_label_en-US" xlink:label="lab_us-gaap_HedgingRelationshipDomain" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Hedging Relationship [Domain]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_HedgingRelationshipDomain" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_HedgingRelationshipDomain"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_HedgingRelationshipDomain" xlink:to="lab_us-gaap_HedgingRelationshipDomain" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_InvestmentsClassifiedByContractualMaturityDateTableTextBlock_c9aab40d-ebbe-4a34-ad86-7171f7d79538_terseLabel_en-US" xlink:label="lab_us-gaap_InvestmentsClassifiedByContractualMaturityDateTableTextBlock" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Schedule of Amortized Cost and Fair Value of Securities by Contractual Maturities</link:label>
    <link:label id="lab_us-gaap_InvestmentsClassifiedByContractualMaturityDateTableTextBlock_label_en-US" xlink:label="lab_us-gaap_InvestmentsClassifiedByContractualMaturityDateTableTextBlock" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Investments Classified by Contractual Maturity Date [Table Text Block]</link:label>
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    <link:label id="lab_us-gaap_HedgingDesignationAxis_094634dd-9b47-4591-b7dc-44e2b07046e7_terseLabel_en-US" xlink:label="lab_us-gaap_HedgingDesignationAxis" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Hedging Designation [Axis]</link:label>
    <link:label id="lab_us-gaap_HedgingDesignationAxis_label_en-US" xlink:label="lab_us-gaap_HedgingDesignationAxis" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Hedging Designation [Axis]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_HedgingDesignationAxis" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_HedgingDesignationAxis"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_HedgingDesignationAxis" xlink:to="lab_us-gaap_HedgingDesignationAxis" xlink:type="arc" order="1"/>
    <link:label id="lab_dei_EntityFilerCategory_ba0f3044-cea5-4b0a-b0ea-ed0d12d07aef_terseLabel_en-US" xlink:label="lab_dei_EntityFilerCategory" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Entity Filer Category</link:label>
    <link:label id="lab_dei_EntityFilerCategory_label_en-US" xlink:label="lab_dei_EntityFilerCategory" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Entity Filer Category</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityFilerCategory" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_EntityFilerCategory"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_dei_EntityFilerCategory" xlink:to="lab_dei_EntityFilerCategory" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_DerivativeAssetFairValueGrossLiability_462e9003-d26e-4fd7-be49-82cf0a46f4c7_negatedTerseLabel_en-US" xlink:label="lab_us-gaap_DerivativeAssetFairValueGrossLiability" xlink:role="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Impact of master netting agreement</link:label>
    <link:label id="lab_us-gaap_DerivativeAssetFairValueGrossLiability_label_en-US" xlink:label="lab_us-gaap_DerivativeAssetFairValueGrossLiability" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Derivative Asset, Subject to Master Netting Arrangement, Liability Offset</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeAssetFairValueGrossLiability" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_DerivativeAssetFairValueGrossLiability"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_DerivativeAssetFairValueGrossLiability" xlink:to="lab_us-gaap_DerivativeAssetFairValueGrossLiability" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_LiabilitiesFairValueDisclosureAbstract_8618d297-0493-49ca-9fff-0673adfc12f5_terseLabel_en-US" xlink:label="lab_us-gaap_LiabilitiesFairValueDisclosureAbstract" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Liabilities:</link:label>
    <link:label id="lab_us-gaap_LiabilitiesFairValueDisclosureAbstract_label_en-US" xlink:label="lab_us-gaap_LiabilitiesFairValueDisclosureAbstract" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Liabilities, Fair Value Disclosure [Abstract]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LiabilitiesFairValueDisclosureAbstract" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_LiabilitiesFairValueDisclosureAbstract"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_LiabilitiesFairValueDisclosureAbstract" xlink:to="lab_us-gaap_LiabilitiesFairValueDisclosureAbstract" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_CommitmentsAndContingencies_9918ee17-c656-425f-b544-d844809673f4_terseLabel_en-US" xlink:label="lab_us-gaap_CommitmentsAndContingencies" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Commitments and contingencies</link:label>
    <link:label id="lab_us-gaap_CommitmentsAndContingencies_label_en-US" xlink:label="lab_us-gaap_CommitmentsAndContingencies" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Commitments and Contingencies</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommitmentsAndContingencies" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_CommitmentsAndContingencies"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_CommitmentsAndContingencies" xlink:to="lab_us-gaap_CommitmentsAndContingencies" xlink:type="arc" order="1"/>
    <link:label id="lab_dei_SecurityExchangeName_7ac98748-4d69-43b2-99e9-0cf1c4c504ac_terseLabel_en-US" xlink:label="lab_dei_SecurityExchangeName" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Security Exchange Name</link:label>
    <link:label id="lab_dei_SecurityExchangeName_label_en-US" xlink:label="lab_dei_SecurityExchangeName" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Security Exchange Name</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_dei_SecurityExchangeName" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_SecurityExchangeName"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_dei_SecurityExchangeName" xlink:to="lab_dei_SecurityExchangeName" xlink:type="arc" order="1"/>
    <link:label id="lab_slm_Maturity2024Member_833d9a8a-9a71-4ea9-ba52-a671bfe6d918_terseLabel_en-US" xlink:label="lab_slm_Maturity2024Member" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">2024</link:label>
    <link:label id="lab_slm_Maturity2024Member_label_en-US" xlink:label="lab_slm_Maturity2024Member" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Maturity 2024 [Member]</link:label>
    <link:label id="lab_slm_Maturity2024Member_documentation_en-US" xlink:label="lab_slm_Maturity2024Member" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Maturity 2024</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_slm_Maturity2024Member" xlink:href="slm-20230331.xsd#slm_Maturity2024Member"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_slm_Maturity2024Member" xlink:to="lab_slm_Maturity2024Member" xlink:type="arc" order="1"/>
    <link:label id="lab_slm_Maturity2044Member_9e6913ad-efbf-4ada-9c09-a15f72ba33cc_terseLabel_en-US" xlink:label="lab_slm_Maturity2044Member" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">2044</link:label>
    <link:label id="lab_slm_Maturity2044Member_label_en-US" xlink:label="lab_slm_Maturity2044Member" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Maturity 2044 [Member]</link:label>
    <link:label id="lab_slm_Maturity2044Member_documentation_en-US" xlink:label="lab_slm_Maturity2044Member" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Maturity 2044 [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_slm_Maturity2044Member" xlink:href="slm-20230331.xsd#slm_Maturity2044Member"/>
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    <link:label id="lab_us-gaap_AcquiredFiniteLivedIntangibleAssetsWeightedAverageUsefulLife_d60278b3-1a6b-4c0e-8a66-7d16a0ec1bf6_terseLabel_en-US" xlink:label="lab_us-gaap_AcquiredFiniteLivedIntangibleAssetsWeightedAverageUsefulLife" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Weighted average useful life of acquired intangible assets</link:label>
    <link:label id="lab_us-gaap_AcquiredFiniteLivedIntangibleAssetsWeightedAverageUsefulLife_label_en-US" xlink:label="lab_us-gaap_AcquiredFiniteLivedIntangibleAssetsWeightedAverageUsefulLife" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Acquired Finite-Lived Intangible Assets, Weighted Average Useful Life</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AcquiredFiniteLivedIntangibleAssetsWeightedAverageUsefulLife" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AcquiredFiniteLivedIntangibleAssetsWeightedAverageUsefulLife"/>
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    <link:label id="lab_us-gaap_FairValueBalanceSheetGroupingFinancialStatementCaptionsLineItems_28dc0c59-cb99-45ff-9505-904b42b030f7_terseLabel_en-US" xlink:label="lab_us-gaap_FairValueBalanceSheetGroupingFinancialStatementCaptionsLineItems" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Fair Value, Balance Sheet Grouping, Financial Statement Captions [Line Items]</link:label>
    <link:label id="lab_us-gaap_FairValueBalanceSheetGroupingFinancialStatementCaptionsLineItems_label_en-US" xlink:label="lab_us-gaap_FairValueBalanceSheetGroupingFinancialStatementCaptionsLineItems" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Fair Value, Balance Sheet Grouping, Financial Statement Captions [Line Items]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueBalanceSheetGroupingFinancialStatementCaptionsLineItems" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_FairValueBalanceSheetGroupingFinancialStatementCaptionsLineItems"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_FairValueBalanceSheetGroupingFinancialStatementCaptionsLineItems" xlink:to="lab_us-gaap_FairValueBalanceSheetGroupingFinancialStatementCaptionsLineItems" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_GainLossOnFairValueHedgesRecognizedInEarningsAbstract_82e22632-6df8-4381-8aa6-42fe23076da3_terseLabel_en-US" xlink:label="lab_us-gaap_GainLossOnFairValueHedgesRecognizedInEarningsAbstract" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Fair Value Hedges</link:label>
    <link:label id="lab_us-gaap_GainLossOnFairValueHedgesRecognizedInEarningsAbstract_label_en-US" xlink:label="lab_us-gaap_GainLossOnFairValueHedgesRecognizedInEarningsAbstract" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Gain (Loss) on Fair Value Hedges Recognized in Earnings [Abstract]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_GainLossOnFairValueHedgesRecognizedInEarningsAbstract" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_GainLossOnFairValueHedgesRecognizedInEarningsAbstract"/>
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    <link:label id="lab_slm_FinancingReceivableAllowanceForCreditLossRecoveryOriginatedTwoYearsBeforeCurrentFiscalYear_fca592b3-0990-4ba4-a83d-4feaad5931bf_terseLabel_en-US" xlink:label="lab_slm_FinancingReceivableAllowanceForCreditLossRecoveryOriginatedTwoYearsBeforeCurrentFiscalYear" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Current period recoveries, Year 3</link:label>
    <link:label id="lab_slm_FinancingReceivableAllowanceForCreditLossRecoveryOriginatedTwoYearsBeforeCurrentFiscalYear_label_en-US" xlink:label="lab_slm_FinancingReceivableAllowanceForCreditLossRecoveryOriginatedTwoYearsBeforeCurrentFiscalYear" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Financing Receivable, Allowance for Credit Loss, Recovery, Originated Two Years Before Current Fiscal Year</link:label>
    <link:label id="lab_slm_FinancingReceivableAllowanceForCreditLossRecoveryOriginatedTwoYearsBeforeCurrentFiscalYear_documentation_en-US" xlink:label="lab_slm_FinancingReceivableAllowanceForCreditLossRecoveryOriginatedTwoYearsBeforeCurrentFiscalYear" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Financing Receivable, Allowance for Credit Loss, Recovery, Originated Two Years Before Current Fiscal Year</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_slm_FinancingReceivableAllowanceForCreditLossRecoveryOriginatedTwoYearsBeforeCurrentFiscalYear" xlink:href="slm-20230331.xsd#slm_FinancingReceivableAllowanceForCreditLossRecoveryOriginatedTwoYearsBeforeCurrentFiscalYear"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_slm_FinancingReceivableAllowanceForCreditLossRecoveryOriginatedTwoYearsBeforeCurrentFiscalYear" xlink:to="lab_slm_FinancingReceivableAllowanceForCreditLossRecoveryOriginatedTwoYearsBeforeCurrentFiscalYear" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_FinancialInstrumentsFinancialLiabilitiesBalanceSheetGroupingsAbstract_4dfbeec7-7804-4162-a829-6a84fef61817_terseLabel_en-US" xlink:label="lab_us-gaap_FinancialInstrumentsFinancialLiabilitiesBalanceSheetGroupingsAbstract" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Interest-bearing liabilities:</link:label>
    <link:label id="lab_us-gaap_FinancialInstrumentsFinancialLiabilitiesBalanceSheetGroupingsAbstract_label_en-US" xlink:label="lab_us-gaap_FinancialInstrumentsFinancialLiabilitiesBalanceSheetGroupingsAbstract" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Financial Instruments, Financial Liabilities, Balance Sheet Groupings [Abstract]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinancialInstrumentsFinancialLiabilitiesBalanceSheetGroupingsAbstract" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_FinancialInstrumentsFinancialLiabilitiesBalanceSheetGroupingsAbstract"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_FinancialInstrumentsFinancialLiabilitiesBalanceSheetGroupingsAbstract" xlink:to="lab_us-gaap_FinancialInstrumentsFinancialLiabilitiesBalanceSheetGroupingsAbstract" xlink:type="arc" order="1"/>
    <link:label id="lab_slm_FinancingReceivableAllowanceForCreditLossOriginatedFiscalYearBeforeLatestFiscalYear_269c3510-4378-4ddb-8237-2dbd04761de5_negatedTerseLabel_en-US" xlink:label="lab_slm_FinancingReceivableAllowanceForCreditLossOriginatedFiscalYearBeforeLatestFiscalYear" xlink:role="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Private Education Loans allowance for losses, Year 2</link:label>
    <link:label id="lab_slm_FinancingReceivableAllowanceForCreditLossOriginatedFiscalYearBeforeLatestFiscalYear_label_en-US" xlink:label="lab_slm_FinancingReceivableAllowanceForCreditLossOriginatedFiscalYearBeforeLatestFiscalYear" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Financing Receivable, Allowance For Credit Loss, Originated Fiscal Year Before Latest Fiscal Year</link:label>
    <link:label id="lab_slm_FinancingReceivableAllowanceForCreditLossOriginatedFiscalYearBeforeLatestFiscalYear_documentation_en-US" xlink:label="lab_slm_FinancingReceivableAllowanceForCreditLossOriginatedFiscalYearBeforeLatestFiscalYear" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Financing Receivable, Allowance For Credit Loss, Originated Fiscal Year Before Latest Fiscal Year</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_slm_FinancingReceivableAllowanceForCreditLossOriginatedFiscalYearBeforeLatestFiscalYear" xlink:href="slm-20230331.xsd#slm_FinancingReceivableAllowanceForCreditLossOriginatedFiscalYearBeforeLatestFiscalYear"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_slm_FinancingReceivableAllowanceForCreditLossOriginatedFiscalYearBeforeLatestFiscalYear" xlink:to="lab_slm_FinancingReceivableAllowanceForCreditLossOriginatedFiscalYearBeforeLatestFiscalYear" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_CapitalToRiskWeightedAssets_9aae0622-5ebb-47a1-88f2-1c27dc51052a_terseLabel_en-US" xlink:label="lab_us-gaap_CapitalToRiskWeightedAssets" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Total Capital (to Risk-Weighted Assets)</link:label>
    <link:label id="lab_us-gaap_CapitalToRiskWeightedAssets_label_en-US" xlink:label="lab_us-gaap_CapitalToRiskWeightedAssets" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Banking Regulation, Total Risk-Based Capital Ratio, Actual</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CapitalToRiskWeightedAssets" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_CapitalToRiskWeightedAssets"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_CapitalToRiskWeightedAssets" xlink:to="lab_us-gaap_CapitalToRiskWeightedAssets" xlink:type="arc" order="1"/>
    <link:label id="lab_slm_FinancingReceivableLoansInForbearanceYearTwoOriginatedFiscalYearBeforeCurrentFiscalYear_797e6fa4-4ba3-481a-af5c-6c19130da904_terseLabel_en-US" xlink:label="lab_slm_FinancingReceivableLoansInForbearanceYearTwoOriginatedFiscalYearBeforeCurrentFiscalYear" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Total Private Education Loans in forbearance, Year 2</link:label>
    <link:label id="lab_slm_FinancingReceivableLoansInForbearanceYearTwoOriginatedFiscalYearBeforeCurrentFiscalYear_label_en-US" xlink:label="lab_slm_FinancingReceivableLoansInForbearanceYearTwoOriginatedFiscalYearBeforeCurrentFiscalYear" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Financing Receivable, Loans In Forbearance, Year Two, Originated, Fiscal Year before Current Fiscal Year</link:label>
    <link:label id="lab_slm_FinancingReceivableLoansInForbearanceYearTwoOriginatedFiscalYearBeforeCurrentFiscalYear_documentation_en-US" xlink:label="lab_slm_FinancingReceivableLoansInForbearanceYearTwoOriginatedFiscalYearBeforeCurrentFiscalYear" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Financing Receivable, Loans In Forbearance, Year Two, Originated, Fiscal Year before Current Fiscal Year</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_slm_FinancingReceivableLoansInForbearanceYearTwoOriginatedFiscalYearBeforeCurrentFiscalYear" xlink:href="slm-20230331.xsd#slm_FinancingReceivableLoansInForbearanceYearTwoOriginatedFiscalYearBeforeCurrentFiscalYear"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_slm_FinancingReceivableLoansInForbearanceYearTwoOriginatedFiscalYearBeforeCurrentFiscalYear" xlink:to="lab_slm_FinancingReceivableLoansInForbearanceYearTwoOriginatedFiscalYearBeforeCurrentFiscalYear" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_FinancingReceivables60To89DaysPastDueMember_08c9690d-0b03-483c-ac15-9411c965f3a4_verboseLabel_en-US" xlink:label="lab_us-gaap_FinancingReceivables60To89DaysPastDueMember" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">60-89 Days Past Due</link:label>
    <link:label id="lab_us-gaap_FinancingReceivables60To89DaysPastDueMember_73323871-2849-4bcf-b69b-1f8357e93053_terseLabel_en-US" xlink:label="lab_us-gaap_FinancingReceivables60To89DaysPastDueMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Loan delinquent 60-89 days</link:label>
    <link:label id="lab_us-gaap_FinancingReceivables60To89DaysPastDueMember_label_en-US" xlink:label="lab_us-gaap_FinancingReceivables60To89DaysPastDueMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Financial Asset, 60 to 89 Days Past Due [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinancingReceivables60To89DaysPastDueMember" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_FinancingReceivables60To89DaysPastDueMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_FinancingReceivables60To89DaysPastDueMember" xlink:to="lab_us-gaap_FinancingReceivables60To89DaysPastDueMember" xlink:type="arc" order="1"/>
    <link:label id="lab_dei_CoverAbstract_6b4691a9-3f48-4adb-bf30-f860cac0559c_terseLabel_en-US" xlink:label="lab_dei_CoverAbstract" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Cover page.</link:label>
    <link:label id="lab_dei_CoverAbstract_label_en-US" xlink:label="lab_dei_CoverAbstract" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Cover [Abstract]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_dei_CoverAbstract" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_CoverAbstract"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_dei_CoverAbstract" xlink:to="lab_dei_CoverAbstract" xlink:type="arc" order="1"/>
    <link:label id="lab_slm_DelinquenciesAsPercentageOfLoansInRepaymentOriginatedInCurrentFiscalYear_b4218dea-7d38-4e0c-8dae-07f230ccae1e_terseLabel_en-US" xlink:label="lab_slm_DelinquenciesAsPercentageOfLoansInRepaymentOriginatedInCurrentFiscalYear" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Delinquent Private Education Loans in repayment as a percentage of Private Education Loans in repayment, Year 1</link:label>
    <link:label id="lab_slm_DelinquenciesAsPercentageOfLoansInRepaymentOriginatedInCurrentFiscalYear_label_en-US" xlink:label="lab_slm_DelinquenciesAsPercentageOfLoansInRepaymentOriginatedInCurrentFiscalYear" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Delinquencies As Percentage Of Loans In Repayment, Originated In Current Fiscal Year</link:label>
    <link:label id="lab_slm_DelinquenciesAsPercentageOfLoansInRepaymentOriginatedInCurrentFiscalYear_documentation_en-US" xlink:label="lab_slm_DelinquenciesAsPercentageOfLoansInRepaymentOriginatedInCurrentFiscalYear" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Delinquencies As Percentage Of Loans In Repayment, Originated In Current Fiscal Year</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_slm_DelinquenciesAsPercentageOfLoansInRepaymentOriginatedInCurrentFiscalYear" xlink:href="slm-20230331.xsd#slm_DelinquenciesAsPercentageOfLoansInRepaymentOriginatedInCurrentFiscalYear"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_slm_DelinquenciesAsPercentageOfLoansInRepaymentOriginatedInCurrentFiscalYear" xlink:to="lab_slm_DelinquenciesAsPercentageOfLoansInRepaymentOriginatedInCurrentFiscalYear" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_FinancingReceivableExcludingAccruedInterestYearOneOriginatedCurrentFiscalYear_69083e35-bc31-4e77-ba40-176c2254f61f_terseLabel_en-US" xlink:label="lab_us-gaap_FinancingReceivableExcludingAccruedInterestYearOneOriginatedCurrentFiscalYear" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Year 1</link:label>
    <link:label id="lab_us-gaap_FinancingReceivableExcludingAccruedInterestYearOneOriginatedCurrentFiscalYear_label_en-US" xlink:label="lab_us-gaap_FinancingReceivableExcludingAccruedInterestYearOneOriginatedCurrentFiscalYear" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Financing Receivable, Excluding Accrued Interest, Year One, Originated, Current Fiscal Year</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinancingReceivableExcludingAccruedInterestYearOneOriginatedCurrentFiscalYear" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_FinancingReceivableExcludingAccruedInterestYearOneOriginatedCurrentFiscalYear"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_FinancingReceivableExcludingAccruedInterestYearOneOriginatedCurrentFiscalYear" xlink:to="lab_us-gaap_FinancingReceivableExcludingAccruedInterestYearOneOriginatedCurrentFiscalYear" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_InterestExpenseShortTermBorrowings_1ef681eb-0cba-4bfe-9c8b-ba3ed381d031_terseLabel_en-US" xlink:label="lab_us-gaap_InterestExpenseShortTermBorrowings" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Interest expense on short-term borrowings</link:label>
    <link:label id="lab_us-gaap_InterestExpenseShortTermBorrowings_label_en-US" xlink:label="lab_us-gaap_InterestExpenseShortTermBorrowings" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Interest Expense, Short-Term Borrowings</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestExpenseShortTermBorrowings" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_InterestExpenseShortTermBorrowings"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_InterestExpenseShortTermBorrowings" xlink:to="lab_us-gaap_InterestExpenseShortTermBorrowings" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_FinancingReceivableSale_a6f9fe48-cd25-4b42-a334-bf9fa538a261_terseLabel_en-US" xlink:label="lab_us-gaap_FinancingReceivableSale" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Sale of financing receivables</link:label>
    <link:label id="lab_us-gaap_FinancingReceivableSale_label_en-US" xlink:label="lab_us-gaap_FinancingReceivableSale" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Financing Receivable, Sale</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinancingReceivableSale" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_FinancingReceivableSale"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_FinancingReceivableSale" xlink:to="lab_us-gaap_FinancingReceivableSale" xlink:type="arc" order="1"/>
    <link:label id="lab_slm_TreasuryStockAcquiredAverageCostPerShareIncludingCommissionCosts_e4221543-b8c5-4896-84f4-9457ef5171cc_terseLabel_en-US" xlink:label="lab_slm_TreasuryStockAcquiredAverageCostPerShareIncludingCommissionCosts" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Average purchase price per share (in dollars per share)</link:label>
    <link:label id="lab_slm_TreasuryStockAcquiredAverageCostPerShareIncludingCommissionCosts_label_en-US" xlink:label="lab_slm_TreasuryStockAcquiredAverageCostPerShareIncludingCommissionCosts" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Treasury Stock Acquired, Average Cost Per Share, Including Commission Costs</link:label>
    <link:label id="lab_slm_TreasuryStockAcquiredAverageCostPerShareIncludingCommissionCosts_documentation_en-US" xlink:label="lab_slm_TreasuryStockAcquiredAverageCostPerShareIncludingCommissionCosts" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Treasury Stock Acquired, Average Cost Per Share, Including Commission Costs</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_slm_TreasuryStockAcquiredAverageCostPerShareIncludingCommissionCosts" xlink:href="slm-20230331.xsd#slm_TreasuryStockAcquiredAverageCostPerShareIncludingCommissionCosts"/>
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    <link:label id="lab_us-gaap_OtherAssets_be9df887-9d1f-4f7b-bcc8-6663f19bcc13_verboseLabel_en-US" xlink:label="lab_us-gaap_OtherAssets" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Other assets</link:label>
    <link:label id="lab_us-gaap_OtherAssets_644eb38f-9502-4d58-8097-d5bc41508b7c_terseLabel_en-US" xlink:label="lab_us-gaap_OtherAssets" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Other Assets</link:label>
    <link:label id="lab_us-gaap_OtherAssets_label_en-US" xlink:label="lab_us-gaap_OtherAssets" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Other Assets</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherAssets" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_OtherAssets"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_OtherAssets" xlink:to="lab_us-gaap_OtherAssets" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_InvestmentTypeCategorizationMember_1f63979f-4af9-4329-861a-1cb6c3613e71_terseLabel_en-US" xlink:label="lab_us-gaap_InvestmentTypeCategorizationMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Investments [Domain]</link:label>
    <link:label id="lab_us-gaap_InvestmentTypeCategorizationMember_label_en-US" xlink:label="lab_us-gaap_InvestmentTypeCategorizationMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Investments [Domain]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InvestmentTypeCategorizationMember" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_InvestmentTypeCategorizationMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_InvestmentTypeCategorizationMember" xlink:to="lab_us-gaap_InvestmentTypeCategorizationMember" xlink:type="arc" order="1"/>
    <link:label id="lab_srt_ScenarioForecastMember_be6c716f-2b0f-476b-be85-771cf6540bf8_terseLabel_en-US" xlink:label="lab_srt_ScenarioForecastMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Forecast</link:label>
    <link:label id="lab_srt_ScenarioForecastMember_label_en-US" xlink:label="lab_srt_ScenarioForecastMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Forecast [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_srt_ScenarioForecastMember" xlink:href="https://xbrl.fasb.org/srt/2022/elts/srt-2022.xsd#srt_ScenarioForecastMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_srt_ScenarioForecastMember" xlink:to="lab_srt_ScenarioForecastMember" xlink:type="arc" order="1"/>
    <link:label id="lab_slm_LoanAmountSecuritized_b7dd4d67-86c5-4c92-ae44-5ef6ef7c68af_terseLabel_en-US" xlink:label="lab_slm_LoanAmountSecuritized" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Total loans and accrued interest amount securitized at inception</link:label>
    <link:label id="lab_slm_LoanAmountSecuritized_label_en-US" xlink:label="lab_slm_LoanAmountSecuritized" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Loan Amount Securitized</link:label>
    <link:label id="lab_slm_LoanAmountSecuritized_documentation_en-US" xlink:label="lab_slm_LoanAmountSecuritized" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Loan Amount Securitized</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_slm_LoanAmountSecuritized" xlink:href="slm-20230331.xsd#slm_LoanAmountSecuritized"/>
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    <link:label id="lab_us-gaap_ContractualObligation_4234884a-2775-4d0d-8e94-dc27ce04b75e_terseLabel_en-US" xlink:label="lab_us-gaap_ContractualObligation" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Contractual obligation</link:label>
    <link:label id="lab_us-gaap_ContractualObligation_label_en-US" xlink:label="lab_us-gaap_ContractualObligation" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Contractual Obligation</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ContractualObligation" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ContractualObligation"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_ContractualObligation" xlink:to="lab_us-gaap_ContractualObligation" xlink:type="arc" order="1"/>
    <link:label id="lab_slm_NetUnamortizedPremiumOrDiscountOriginatedThreeYearsBeforeCurrentFiscalYear_f401253b-6e12-473e-a406-1b748edaa501_terseLabel_en-US" xlink:label="lab_slm_NetUnamortizedPremiumOrDiscountOriginatedThreeYearsBeforeCurrentFiscalYear" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Private Education Loans deferred origination costs and unamortized premium/(discount), Year 4</link:label>
    <link:label id="lab_slm_NetUnamortizedPremiumOrDiscountOriginatedThreeYearsBeforeCurrentFiscalYear_label_en-US" xlink:label="lab_slm_NetUnamortizedPremiumOrDiscountOriginatedThreeYearsBeforeCurrentFiscalYear" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Net Unamortized Premium Or Discount, Originated Three Years Before Current Fiscal Year</link:label>
    <link:label id="lab_slm_NetUnamortizedPremiumOrDiscountOriginatedThreeYearsBeforeCurrentFiscalYear_documentation_en-US" xlink:label="lab_slm_NetUnamortizedPremiumOrDiscountOriginatedThreeYearsBeforeCurrentFiscalYear" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Net Unamortized Premium Or Discount, Originated Three Years Before Current Fiscal Year</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_slm_NetUnamortizedPremiumOrDiscountOriginatedThreeYearsBeforeCurrentFiscalYear" xlink:href="slm-20230331.xsd#slm_NetUnamortizedPremiumOrDiscountOriginatedThreeYearsBeforeCurrentFiscalYear"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_slm_NetUnamortizedPremiumOrDiscountOriginatedThreeYearsBeforeCurrentFiscalYear" xlink:to="lab_slm_NetUnamortizedPremiumOrDiscountOriginatedThreeYearsBeforeCurrentFiscalYear" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_AociTaxAttributableToParent_406b0ce3-7fbe-4e8e-bfea-5b492db03ef9_terseLabel_en-US" xlink:label="lab_us-gaap_AociTaxAttributableToParent" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Tax benefit on accumulated other comprehensive loss</link:label>
    <link:label id="lab_us-gaap_AociTaxAttributableToParent_label_en-US" xlink:label="lab_us-gaap_AociTaxAttributableToParent" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">AOCI Tax, Attributable to Parent</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AociTaxAttributableToParent" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AociTaxAttributableToParent"/>
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    <link:label id="lab_slm_LoansInSchoolGraceDefermentMember_9e96cb37-922a-49e7-8e7c-b41f1db45f96_verboseLabel_en-US" xlink:label="lab_slm_LoansInSchoolGraceDefermentMember" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Deferment</link:label>
    <link:label id="lab_slm_LoansInSchoolGraceDefermentMember_73698386-6c3f-4963-8dc7-b83d594f5d9c_terseLabel_en-US" xlink:label="lab_slm_LoansInSchoolGraceDefermentMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Loans In-School/Grace/Deferment</link:label>
    <link:label id="lab_slm_LoansInSchoolGraceDefermentMember_label_en-US" xlink:label="lab_slm_LoansInSchoolGraceDefermentMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Loans In-School/Grace/Deferment [Member]</link:label>
    <link:label id="lab_slm_LoansInSchoolGraceDefermentMember_documentation_en-US" xlink:label="lab_slm_LoansInSchoolGraceDefermentMember" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Loans In-School/Grace/Deferment</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_slm_LoansInSchoolGraceDefermentMember" xlink:href="slm-20230331.xsd#slm_LoansInSchoolGraceDefermentMember"/>
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    <link:label id="lab_slm_Maturity2043Member_74ec667f-fbf6-4f97-a087-3591627fd441_terseLabel_en-US" xlink:label="lab_slm_Maturity2043Member" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">2043</link:label>
    <link:label id="lab_slm_Maturity2043Member_label_en-US" xlink:label="lab_slm_Maturity2043Member" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Maturity 2043 [Member]</link:label>
    <link:label id="lab_slm_Maturity2043Member_documentation_en-US" xlink:label="lab_slm_Maturity2043Member" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Maturity 2043 [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_slm_Maturity2043Member" xlink:href="slm-20230331.xsd#slm_Maturity2043Member"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_slm_Maturity2043Member" xlink:to="lab_slm_Maturity2043Member" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_LiabilitiesAndStockholdersEquity_fc016d4c-4b14-4a0f-9af6-6babbc5aa27f_totalLabel_en-US" xlink:label="lab_us-gaap_LiabilitiesAndStockholdersEquity" xlink:role="http://www.xbrl.org/2003/role/totalLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Total liabilities and equity</link:label>
    <link:label id="lab_us-gaap_LiabilitiesAndStockholdersEquity_label_en-US" xlink:label="lab_us-gaap_LiabilitiesAndStockholdersEquity" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Liabilities and Equity</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LiabilitiesAndStockholdersEquity" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_LiabilitiesAndStockholdersEquity"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquity" xlink:to="lab_us-gaap_LiabilitiesAndStockholdersEquity" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_DepositsMember_76a0e034-f92a-4e98-8c4e-97c267b7b638_terseLabel_en-US" xlink:label="lab_us-gaap_DepositsMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Deposits</link:label>
    <link:label id="lab_us-gaap_DepositsMember_label_en-US" xlink:label="lab_us-gaap_DepositsMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Deposits [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DepositsMember" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_DepositsMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_DepositsMember" xlink:to="lab_us-gaap_DepositsMember" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_LongtermDebtTypeAxis_f7cd0294-4b08-4e9e-8a39-34f0dc894b6b_terseLabel_en-US" xlink:label="lab_us-gaap_LongtermDebtTypeAxis" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Long-term Debt, Type [Axis]</link:label>
    <link:label id="lab_us-gaap_LongtermDebtTypeAxis_label_en-US" xlink:label="lab_us-gaap_LongtermDebtTypeAxis" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Long-Term Debt, Type [Axis]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongtermDebtTypeAxis" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_LongtermDebtTypeAxis"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_LongtermDebtTypeAxis" xlink:to="lab_us-gaap_LongtermDebtTypeAxis" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_StockRepurchaseProgramRemainingAuthorizedRepurchaseAmount1_690d1fdb-d0f4-44a0-a014-86a30d0a0535_terseLabel_en-US" xlink:label="lab_us-gaap_StockRepurchaseProgramRemainingAuthorizedRepurchaseAmount1" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Remaining authority under the share repurchase program</link:label>
    <link:label id="lab_us-gaap_StockRepurchaseProgramRemainingAuthorizedRepurchaseAmount1_label_en-US" xlink:label="lab_us-gaap_StockRepurchaseProgramRemainingAuthorizedRepurchaseAmount1" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Stock Repurchase Program, Remaining Authorized Repurchase Amount</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockRepurchaseProgramRemainingAuthorizedRepurchaseAmount1" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_StockRepurchaseProgramRemainingAuthorizedRepurchaseAmount1"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_StockRepurchaseProgramRemainingAuthorizedRepurchaseAmount1" xlink:to="lab_us-gaap_StockRepurchaseProgramRemainingAuthorizedRepurchaseAmount1" xlink:type="arc" order="1"/>
    <link:label id="lab_slm_FinancingReceivableLoansInForbearanceYearFiveOriginatedFourYearsBeforeCurrentFiscalYear_0e739197-7ff9-44e8-9502-5faa3cfc2488_terseLabel_en-US" xlink:label="lab_slm_FinancingReceivableLoansInForbearanceYearFiveOriginatedFourYearsBeforeCurrentFiscalYear" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Total Private Education Loans in forbearance, Year 5</link:label>
    <link:label id="lab_slm_FinancingReceivableLoansInForbearanceYearFiveOriginatedFourYearsBeforeCurrentFiscalYear_label_en-US" xlink:label="lab_slm_FinancingReceivableLoansInForbearanceYearFiveOriginatedFourYearsBeforeCurrentFiscalYear" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Financing Receivable, Loans In Forbearance, Year Five, Originated, Four Years before Current Fiscal Year</link:label>
    <link:label id="lab_slm_FinancingReceivableLoansInForbearanceYearFiveOriginatedFourYearsBeforeCurrentFiscalYear_documentation_en-US" xlink:label="lab_slm_FinancingReceivableLoansInForbearanceYearFiveOriginatedFourYearsBeforeCurrentFiscalYear" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Financing Receivable, Loans In Forbearance, Year Five, Originated, Four Years before Current Fiscal Year</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_slm_FinancingReceivableLoansInForbearanceYearFiveOriginatedFourYearsBeforeCurrentFiscalYear" xlink:href="slm-20230331.xsd#slm_FinancingReceivableLoansInForbearanceYearFiveOriginatedFourYearsBeforeCurrentFiscalYear"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_slm_FinancingReceivableLoansInForbearanceYearFiveOriginatedFourYearsBeforeCurrentFiscalYear" xlink:to="lab_slm_FinancingReceivableLoansInForbearanceYearFiveOriginatedFourYearsBeforeCurrentFiscalYear" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_NondesignatedMember_eb266dd6-d86c-4468-8c75-dfca70be19be_verboseLabel_en-US" xlink:label="lab_us-gaap_NondesignatedMember" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Trading</link:label>
    <link:label id="lab_us-gaap_NondesignatedMember_1d198fa3-6317-4180-9f12-5da2af9294af_terseLabel_en-US" xlink:label="lab_us-gaap_NondesignatedMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Trading</link:label>
    <link:label id="lab_us-gaap_NondesignatedMember_label_en-US" xlink:label="lab_us-gaap_NondesignatedMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Not Designated as Hedging Instrument [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NondesignatedMember" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_NondesignatedMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_NondesignatedMember" xlink:to="lab_us-gaap_NondesignatedMember" xlink:type="arc" order="1"/>
    <link:label id="lab_slm_AllowanceCoverageOfChargeOffsEndingLoans_9c0dbf03-1b3a-45b6-a8c6-9be266f56b16_terseLabel_en-US" xlink:label="lab_slm_AllowanceCoverageOfChargeOffsEndingLoans" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Ending total loans, gross</link:label>
    <link:label id="lab_slm_AllowanceCoverageOfChargeOffsEndingLoans_label_en-US" xlink:label="lab_slm_AllowanceCoverageOfChargeOffsEndingLoans" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Allowance Coverage Of Charge Offs Ending Loans</link:label>
    <link:label id="lab_slm_AllowanceCoverageOfChargeOffsEndingLoans_documentation_en-US" xlink:label="lab_slm_AllowanceCoverageOfChargeOffsEndingLoans" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Allowance coverage of charge-offs ending total loans.</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_slm_AllowanceCoverageOfChargeOffsEndingLoans" xlink:href="slm-20230331.xsd#slm_AllowanceCoverageOfChargeOffsEndingLoans"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_slm_AllowanceCoverageOfChargeOffsEndingLoans" xlink:to="lab_slm_AllowanceCoverageOfChargeOffsEndingLoans" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_NetIncomeLossAvailableToCommonStockholdersDiluted_54bbe4a2-9c0a-465b-aaa2-c7bfa2405ed6_totalLabel_en-US" xlink:label="lab_us-gaap_NetIncomeLossAvailableToCommonStockholdersDiluted" xlink:role="http://www.xbrl.org/2003/role/totalLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Net income attributable to SLM Corporation common stock</link:label>
    <link:label id="lab_us-gaap_NetIncomeLossAvailableToCommonStockholdersDiluted_label_en-US" xlink:label="lab_us-gaap_NetIncomeLossAvailableToCommonStockholdersDiluted" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Net Income (Loss) Available to Common Stockholders, Diluted</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetIncomeLossAvailableToCommonStockholdersDiluted" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_NetIncomeLossAvailableToCommonStockholdersDiluted"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_NetIncomeLossAvailableToCommonStockholdersDiluted" xlink:to="lab_us-gaap_NetIncomeLossAvailableToCommonStockholdersDiluted" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_EarningsPerShareDiluted_e9050fe1-4d35-4adf-b9b5-37ff62161950_terseLabel_en-US" xlink:label="lab_us-gaap_EarningsPerShareDiluted" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Diluted earnings per common share (in dollars per share)</link:label>
    <link:label id="lab_us-gaap_EarningsPerShareDiluted_label_en-US" xlink:label="lab_us-gaap_EarningsPerShareDiluted" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Earnings Per Share, Diluted</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EarningsPerShareDiluted" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_EarningsPerShareDiluted"/>
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    <link:label id="lab_us-gaap_TrademarksAndTradeNamesMember_50b84783-1cd6-48b8-ac63-f214b3d38efe_terseLabel_en-US" xlink:label="lab_us-gaap_TrademarksAndTradeNamesMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Tradename and trademarks</link:label>
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    <link:label id="lab_srt_CumulativeEffectPeriodOfAdoptionAdjustmentMember_b89f1b0f-f807-49c6-80fe-deda521e57cc_terseLabel_en-US" xlink:label="lab_srt_CumulativeEffectPeriodOfAdoptionAdjustmentMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Adjustments</link:label>
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    <link:label id="lab_us-gaap_DerivativeFairValueOfDerivativeAsset_3aba2bf5-4ffa-4844-98e2-47fd9b9799cd_verboseLabel_en-US" xlink:label="lab_us-gaap_DerivativeFairValueOfDerivativeAsset" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Gross position</link:label>
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    <link:label id="lab_us-gaap_OtherComprehensiveIncomeLossTax_eab0b3d6-08d8-4ee8-ae2c-3027c2806ad7_negatedLabel_en-US" xlink:label="lab_us-gaap_OtherComprehensiveIncomeLossTax" xlink:role="http://www.xbrl.org/2009/role/negatedLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Income tax (expense) benefit</link:label>
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    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_slm_FinancingReceivableIncrementsInWhichForbearanceIsGranted" xlink:to="lab_slm_FinancingReceivableIncrementsInWhichForbearanceIsGranted" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_TimeDepositMaturitiesTableTextBlock_5c0ce6e3-a16b-48c7-9998-2e6ae7a48adc_terseLabel_en-US" xlink:label="lab_us-gaap_TimeDepositMaturitiesTableTextBlock" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Schedule of Certificates of Deposit Maturities</link:label>
    <link:label id="lab_us-gaap_TimeDepositMaturitiesTableTextBlock_label_en-US" xlink:label="lab_us-gaap_TimeDepositMaturitiesTableTextBlock" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Time Deposit Maturities [Table Text Block]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_TimeDepositMaturitiesTableTextBlock" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_TimeDepositMaturitiesTableTextBlock"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_TimeDepositMaturitiesTableTextBlock" xlink:to="lab_us-gaap_TimeDepositMaturitiesTableTextBlock" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_ClassOfStockDomain_0694790e-4496-491f-b5e8-dc37db7cd70a_terseLabel_en-US" xlink:label="lab_us-gaap_ClassOfStockDomain" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Class of Stock [Domain]</link:label>
    <link:label id="lab_us-gaap_ClassOfStockDomain_label_en-US" xlink:label="lab_us-gaap_ClassOfStockDomain" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Class of Stock [Domain]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfStockDomain" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ClassOfStockDomain"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_ClassOfStockDomain" xlink:to="lab_us-gaap_ClassOfStockDomain" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_TimeDepositMaturitiesRollingYearThree_75b509c1-2a9e-4aa4-aff7-e92dd83d7bf0_terseLabel_en-US" xlink:label="lab_us-gaap_TimeDepositMaturitiesRollingYearThree" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">After two years to three years</link:label>
    <link:label id="lab_us-gaap_TimeDepositMaturitiesRollingYearThree_label_en-US" xlink:label="lab_us-gaap_TimeDepositMaturitiesRollingYearThree" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Time Deposit Maturities, Rolling Year Three</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_TimeDepositMaturitiesRollingYearThree" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_TimeDepositMaturitiesRollingYearThree"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_TimeDepositMaturitiesRollingYearThree" xlink:to="lab_us-gaap_TimeDepositMaturitiesRollingYearThree" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_InterestExpense_153a848a-2732-4459-afc5-a6ea09f15a6b_totalLabel_en-US" xlink:label="lab_us-gaap_InterestExpense" xlink:role="http://www.xbrl.org/2003/role/totalLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Total interest expense</link:label>
    <link:label id="lab_us-gaap_InterestExpense_fe66d679-517a-4a35-b78f-b648ae11b171_terseLabel_en-US" xlink:label="lab_us-gaap_InterestExpense" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Interest expense</link:label>
    <link:label id="lab_us-gaap_InterestExpense_label_en-US" xlink:label="lab_us-gaap_InterestExpense" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Interest Expense</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestExpense" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_InterestExpense"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_InterestExpense" xlink:to="lab_us-gaap_InterestExpense" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_AvailableForSaleSecuritiesAbstract_9de21bb1-7d38-470e-af79-8893569ffc99_terseLabel_en-US" xlink:label="lab_us-gaap_AvailableForSaleSecuritiesAbstract" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">12 months or more</link:label>
    <link:label id="lab_us-gaap_AvailableForSaleSecuritiesAbstract_label_en-US" xlink:label="lab_us-gaap_AvailableForSaleSecuritiesAbstract" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Debt Securities, Available-for-Sale [Abstract]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AvailableForSaleSecuritiesAbstract" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AvailableForSaleSecuritiesAbstract"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_AvailableForSaleSecuritiesAbstract" xlink:to="lab_us-gaap_AvailableForSaleSecuritiesAbstract" xlink:type="arc" order="1"/>
    <link:label id="lab_slm_TierThreeofGovernmentGuarantee_488f22b1-3848-4d3f-9cf4-e08005ac8066_terseLabel_en-US" xlink:label="lab_slm_TierThreeofGovernmentGuarantee" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Tier 3 of government guarantee</link:label>
    <link:label id="lab_slm_TierThreeofGovernmentGuarantee_label_en-US" xlink:label="lab_slm_TierThreeofGovernmentGuarantee" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Tier Three of Government Guarantee</link:label>
    <link:label id="lab_slm_TierThreeofGovernmentGuarantee_documentation_en-US" xlink:label="lab_slm_TierThreeofGovernmentGuarantee" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Tier Three of Government Guarantee</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_slm_TierThreeofGovernmentGuarantee" xlink:href="slm-20230331.xsd#slm_TierThreeofGovernmentGuarantee"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_slm_TierThreeofGovernmentGuarantee" xlink:to="lab_slm_TierThreeofGovernmentGuarantee" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_TimeDepositMaturitiesRollingYearTwo_6573a825-d11a-44a1-804e-11252f3c7bfd_terseLabel_en-US" xlink:label="lab_us-gaap_TimeDepositMaturitiesRollingYearTwo" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">After one year to two years</link:label>
    <link:label id="lab_us-gaap_TimeDepositMaturitiesRollingYearTwo_label_en-US" xlink:label="lab_us-gaap_TimeDepositMaturitiesRollingYearTwo" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Time Deposit Maturities, Rolling Year Two</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_TimeDepositMaturitiesRollingYearTwo" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_TimeDepositMaturitiesRollingYearTwo"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_TimeDepositMaturitiesRollingYearTwo" xlink:to="lab_us-gaap_TimeDepositMaturitiesRollingYearTwo" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_AmortizationOfAcquisitionCosts_7bdef08a-74cd-48cf-8959-7176989c8ab8_terseLabel_en-US" xlink:label="lab_us-gaap_AmortizationOfAcquisitionCosts" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Acquisition transaction costs, net</link:label>
    <link:label id="lab_us-gaap_AmortizationOfAcquisitionCosts_label_en-US" xlink:label="lab_us-gaap_AmortizationOfAcquisitionCosts" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Amortization of Acquisition Costs</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AmortizationOfAcquisitionCosts" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AmortizationOfAcquisitionCosts"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_AmortizationOfAcquisitionCosts" xlink:to="lab_us-gaap_AmortizationOfAcquisitionCosts" xlink:type="arc" order="1"/>
    <link:label id="lab_slm_Maturity2042Member_e7caded3-9924-4682-9ef7-0d40d95241ae_terseLabel_en-US" xlink:label="lab_slm_Maturity2042Member" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">2042</link:label>
    <link:label id="lab_slm_Maturity2042Member_label_en-US" xlink:label="lab_slm_Maturity2042Member" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Maturity 2042 [Member]</link:label>
    <link:label id="lab_slm_Maturity2042Member_documentation_en-US" xlink:label="lab_slm_Maturity2042Member" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Maturity 2042 [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_slm_Maturity2042Member" xlink:href="slm-20230331.xsd#slm_Maturity2042Member"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_slm_Maturity2042Member" xlink:to="lab_slm_Maturity2042Member" xlink:type="arc" order="1"/>
    <link:label id="lab_slm_DepositsFairValueDisclosureDifferenceBetweenCarryingValueandFairValue_59bf82f5-a10e-42fa-a25a-5aef62d4c6ea_terseLabel_en-US" xlink:label="lab_slm_DepositsFairValueDisclosureDifferenceBetweenCarryingValueandFairValue" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Deposits, difference</link:label>
    <link:label id="lab_slm_DepositsFairValueDisclosureDifferenceBetweenCarryingValueandFairValue_label_en-US" xlink:label="lab_slm_DepositsFairValueDisclosureDifferenceBetweenCarryingValueandFairValue" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Deposits, Fair Value Disclosure, Difference Between Carrying Value and Fair Value</link:label>
    <link:label id="lab_slm_DepositsFairValueDisclosureDifferenceBetweenCarryingValueandFairValue_documentation_en-US" xlink:label="lab_slm_DepositsFairValueDisclosureDifferenceBetweenCarryingValueandFairValue" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Deposits, Fair Value Disclosure, Difference Between Carrying Value and Fair Value</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_slm_DepositsFairValueDisclosureDifferenceBetweenCarryingValueandFairValue" xlink:href="slm-20230331.xsd#slm_DepositsFairValueDisclosureDifferenceBetweenCarryingValueandFairValue"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_slm_DepositsFairValueDisclosureDifferenceBetweenCarryingValueandFairValue" xlink:to="lab_slm_DepositsFairValueDisclosureDifferenceBetweenCarryingValueandFairValue" xlink:type="arc" order="1"/>
    <link:label id="lab_slm_FinancingReceivableAllowanceForCreditLossRecoveryOriginatedInCurrentFiscalYear_41bff148-4234-4b43-a4b6-b5bb341a4413_terseLabel_en-US" xlink:label="lab_slm_FinancingReceivableAllowanceForCreditLossRecoveryOriginatedInCurrentFiscalYear" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Current period recoveries, Year 1</link:label>
    <link:label id="lab_slm_FinancingReceivableAllowanceForCreditLossRecoveryOriginatedInCurrentFiscalYear_label_en-US" xlink:label="lab_slm_FinancingReceivableAllowanceForCreditLossRecoveryOriginatedInCurrentFiscalYear" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Financing Receivable, Allowance for Credit Loss, Recovery, Originated In Current Fiscal Year</link:label>
    <link:label id="lab_slm_FinancingReceivableAllowanceForCreditLossRecoveryOriginatedInCurrentFiscalYear_documentation_en-US" xlink:label="lab_slm_FinancingReceivableAllowanceForCreditLossRecoveryOriginatedInCurrentFiscalYear" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Financing Receivable, Allowance for Credit Loss, Recovery, Originated In Current Fiscal Year</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_slm_FinancingReceivableAllowanceForCreditLossRecoveryOriginatedInCurrentFiscalYear" xlink:href="slm-20230331.xsd#slm_FinancingReceivableAllowanceForCreditLossRecoveryOriginatedInCurrentFiscalYear"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_slm_FinancingReceivableAllowanceForCreditLossRecoveryOriginatedInCurrentFiscalYear" xlink:to="lab_slm_FinancingReceivableAllowanceForCreditLossRecoveryOriginatedInCurrentFiscalYear" xlink:type="arc" order="1"/>
    <link:label id="lab_slm_DebtInstrumentWeightedAverageLife_59ac183e-7140-4f76-93b0-836d848cf0cc_terseLabel_en-US" xlink:label="lab_slm_DebtInstrumentWeightedAverageLife" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Weighted Average Life (in years)</link:label>
    <link:label id="lab_slm_DebtInstrumentWeightedAverageLife_label_en-US" xlink:label="lab_slm_DebtInstrumentWeightedAverageLife" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Debt Instrument, Weighted Average Life</link:label>
    <link:label id="lab_slm_DebtInstrumentWeightedAverageLife_documentation_en-US" xlink:label="lab_slm_DebtInstrumentWeightedAverageLife" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Debt Instrument, Weighted Average Life</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_slm_DebtInstrumentWeightedAverageLife" xlink:href="slm-20230331.xsd#slm_DebtInstrumentWeightedAverageLife"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_slm_DebtInstrumentWeightedAverageLife" xlink:to="lab_slm_DebtInstrumentWeightedAverageLife" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_CapitalAbstract_2d6dd574-eef7-4adf-9936-9210583b89d8_terseLabel_en-US" xlink:label="lab_us-gaap_CapitalAbstract" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Actual Amount</link:label>
    <link:label id="lab_us-gaap_CapitalAbstract_label_en-US" xlink:label="lab_us-gaap_CapitalAbstract" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Banking Regulation, Total Capital [Abstract]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CapitalAbstract" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_CapitalAbstract"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_CapitalAbstract" xlink:to="lab_us-gaap_CapitalAbstract" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_HedgedLiabilityFairValueHedge_9e8c778a-08b1-4be8-a24d-d6b0dbc67c53_negatedTerseLabel_en-US" xlink:label="lab_us-gaap_HedgedLiabilityFairValueHedge" xlink:role="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Carrying Amount of the Hedged Assets/(Liabilities)</link:label>
    <link:label id="lab_us-gaap_HedgedLiabilityFairValueHedge_label_en-US" xlink:label="lab_us-gaap_HedgedLiabilityFairValueHedge" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Hedged Liability, Fair Value Hedge</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_HedgedLiabilityFairValueHedge" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_HedgedLiabilityFairValueHedge"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_HedgedLiabilityFairValueHedge" xlink:to="lab_us-gaap_HedgedLiabilityFairValueHedge" xlink:type="arc" order="1"/>
    <link:label id="lab_slm_FinancingReceivableAllowanceForCreditLossExcludingAccruedInterestWriteoffOriginatedInCurrentFiscalYear_175e6cef-abc7-426a-ad4b-3753a4e023d1_negatedTerseLabel_en-US" xlink:label="lab_slm_FinancingReceivableAllowanceForCreditLossExcludingAccruedInterestWriteoffOriginatedInCurrentFiscalYear" xlink:role="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Current period gross charge-offs, Year 1</link:label>
    <link:label id="lab_slm_FinancingReceivableAllowanceForCreditLossExcludingAccruedInterestWriteoffOriginatedInCurrentFiscalYear_label_en-US" xlink:label="lab_slm_FinancingReceivableAllowanceForCreditLossExcludingAccruedInterestWriteoffOriginatedInCurrentFiscalYear" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Financing Receivable, Allowance for Credit Loss, Excluding Accrued Interest, Writeoff, Originated In Current Fiscal Year</link:label>
    <link:label id="lab_slm_FinancingReceivableAllowanceForCreditLossExcludingAccruedInterestWriteoffOriginatedInCurrentFiscalYear_documentation_en-US" xlink:label="lab_slm_FinancingReceivableAllowanceForCreditLossExcludingAccruedInterestWriteoffOriginatedInCurrentFiscalYear" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Financing Receivable, Allowance for Credit Loss, Excluding Accrued Interest, Writeoff, Originated In Current Fiscal Year</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_slm_FinancingReceivableAllowanceForCreditLossExcludingAccruedInterestWriteoffOriginatedInCurrentFiscalYear" xlink:href="slm-20230331.xsd#slm_FinancingReceivableAllowanceForCreditLossExcludingAccruedInterestWriteoffOriginatedInCurrentFiscalYear"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_slm_FinancingReceivableAllowanceForCreditLossExcludingAccruedInterestWriteoffOriginatedInCurrentFiscalYear" xlink:to="lab_slm_FinancingReceivableAllowanceForCreditLossExcludingAccruedInterestWriteoffOriginatedInCurrentFiscalYear" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_UnamortizedLoanCommitmentAndOriginationFeesAndUnamortizedDiscountsOrPremiums_49d9a508-3ffa-4fa8-a54c-bed3827865b9_terseLabel_en-US" xlink:label="lab_us-gaap_UnamortizedLoanCommitmentAndOriginationFeesAndUnamortizedDiscountsOrPremiums" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Deferred origination costs and unamortized premium/(discount)</link:label>
    <link:label id="lab_us-gaap_UnamortizedLoanCommitmentAndOriginationFeesAndUnamortizedDiscountsOrPremiums_label_en-US" xlink:label="lab_us-gaap_UnamortizedLoanCommitmentAndOriginationFeesAndUnamortizedDiscountsOrPremiums" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Unamortized Loan Commitment and Origination Fees and Unamortized Discounts or Premiums</link:label>
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    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_UnamortizedLoanCommitmentAndOriginationFeesAndUnamortizedDiscountsOrPremiums" xlink:to="lab_us-gaap_UnamortizedLoanCommitmentAndOriginationFeesAndUnamortizedDiscountsOrPremiums" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_IncreaseDecreaseInAccruedInterestReceivableNet_e39e22f9-9015-45d7-9145-2e7bd4079b53_negatedLabel_en-US" xlink:label="lab_us-gaap_IncreaseDecreaseInAccruedInterestReceivableNet" xlink:role="http://www.xbrl.org/2009/role/negatedLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Increase in accrued interest receivable</link:label>
    <link:label id="lab_us-gaap_IncreaseDecreaseInAccruedInterestReceivableNet_label_en-US" xlink:label="lab_us-gaap_IncreaseDecreaseInAccruedInterestReceivableNet" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Increase (Decrease) in Accrued Interest Receivable, Net</link:label>
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    <link:label id="lab_us-gaap_FinancialAssetNotPastDueMember_488742ac-c865-417d-b098-55fa0a2d9c2a_verboseLabel_en-US" xlink:label="lab_us-gaap_FinancialAssetNotPastDueMember" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Current</link:label>
    <link:label id="lab_us-gaap_FinancialAssetNotPastDueMember_64a2b883-86d9-4932-bc24-a3badde23a81_terseLabel_en-US" xlink:label="lab_us-gaap_FinancialAssetNotPastDueMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Loan delinquent, current</link:label>
    <link:label id="lab_us-gaap_FinancialAssetNotPastDueMember_label_en-US" xlink:label="lab_us-gaap_FinancialAssetNotPastDueMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Financial Asset, Not Past Due [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinancialAssetNotPastDueMember" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_FinancialAssetNotPastDueMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_FinancialAssetNotPastDueMember" xlink:to="lab_us-gaap_FinancialAssetNotPastDueMember" xlink:type="arc" order="1"/>
    <link:label id="lab_slm_FinancingReceivableAfterAllowanceForCreditLossOriginatedFiveYearsBeforeCurrentFiscalYear_cb4c9f67-0b4b-46a2-8f46-fb0abe4683a4_terseLabel_en-US" xlink:label="lab_slm_FinancingReceivableAfterAllowanceForCreditLossOriginatedFiveYearsBeforeCurrentFiscalYear" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Private Education Loans, net, After Year 5</link:label>
    <link:label id="lab_slm_FinancingReceivableAfterAllowanceForCreditLossOriginatedFiveYearsBeforeCurrentFiscalYear_label_en-US" xlink:label="lab_slm_FinancingReceivableAfterAllowanceForCreditLossOriginatedFiveYearsBeforeCurrentFiscalYear" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Financing Receivable, after Allowance for Credit Loss, Originated Five Years Before Current Fiscal Year</link:label>
    <link:label id="lab_slm_FinancingReceivableAfterAllowanceForCreditLossOriginatedFiveYearsBeforeCurrentFiscalYear_documentation_en-US" xlink:label="lab_slm_FinancingReceivableAfterAllowanceForCreditLossOriginatedFiveYearsBeforeCurrentFiscalYear" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Financing Receivable, after Allowance for Credit Loss, Originated Five Years Before Current Fiscal Year</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_slm_FinancingReceivableAfterAllowanceForCreditLossOriginatedFiveYearsBeforeCurrentFiscalYear" xlink:href="slm-20230331.xsd#slm_FinancingReceivableAfterAllowanceForCreditLossOriginatedFiveYearsBeforeCurrentFiscalYear"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_slm_FinancingReceivableAfterAllowanceForCreditLossOriginatedFiveYearsBeforeCurrentFiscalYear" xlink:to="lab_slm_FinancingReceivableAfterAllowanceForCreditLossOriginatedFiveYearsBeforeCurrentFiscalYear" xlink:type="arc" order="1"/>
    <link:label id="lab_slm_PercentageOfLoansInRepaymentOriginatedFiveOrMoreYearsBeforeLatestFiscalYear_911036f0-f696-424c-a095-d126033ffb26_terseLabel_en-US" xlink:label="lab_slm_PercentageOfLoansInRepaymentOriginatedFiveOrMoreYearsBeforeLatestFiscalYear" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Percentage of Private Education Loans in repayment, After Year 5</link:label>
    <link:label id="lab_slm_PercentageOfLoansInRepaymentOriginatedFiveOrMoreYearsBeforeLatestFiscalYear_label_en-US" xlink:label="lab_slm_PercentageOfLoansInRepaymentOriginatedFiveOrMoreYearsBeforeLatestFiscalYear" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Percentage Of Loans In Repayment, Originated Five Or More Years Before Latest Fiscal Year</link:label>
    <link:label id="lab_slm_PercentageOfLoansInRepaymentOriginatedFiveOrMoreYearsBeforeLatestFiscalYear_documentation_en-US" xlink:label="lab_slm_PercentageOfLoansInRepaymentOriginatedFiveOrMoreYearsBeforeLatestFiscalYear" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Percentage Of Loans In Repayment, Originated Five Or More Years Before Latest Fiscal Year</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_slm_PercentageOfLoansInRepaymentOriginatedFiveOrMoreYearsBeforeLatestFiscalYear" xlink:href="slm-20230331.xsd#slm_PercentageOfLoansInRepaymentOriginatedFiveOrMoreYearsBeforeLatestFiscalYear"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_slm_PercentageOfLoansInRepaymentOriginatedFiveOrMoreYearsBeforeLatestFiscalYear" xlink:to="lab_slm_PercentageOfLoansInRepaymentOriginatedFiveOrMoreYearsBeforeLatestFiscalYear" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFive_6d50d886-c769-4bf5-a898-c78640328870_terseLabel_en-US" xlink:label="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFive" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Expected amortization of 2027</link:label>
    <link:label id="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFive_label_en-US" xlink:label="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFive" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Finite-Lived Intangible Asset, Expected Amortization, Year Five</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFive" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFive"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFive" xlink:to="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFive" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_AmortizationOfDeferredLoanOriginationFeesNet_6ae1d506-8d8f-4ebf-b465-d2a5c931512c_negatedTerseLabel_en-US" xlink:label="lab_us-gaap_AmortizationOfDeferredLoanOriginationFeesNet" xlink:role="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Amortization of deferred loan origination costs and loan premium/(discounts), net</link:label>
    <link:label id="lab_us-gaap_AmortizationOfDeferredLoanOriginationFeesNet_label_en-US" xlink:label="lab_us-gaap_AmortizationOfDeferredLoanOriginationFeesNet" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Amortization of Deferred Loan Origination Fees, Net</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AmortizationOfDeferredLoanOriginationFeesNet" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AmortizationOfDeferredLoanOriginationFeesNet"/>
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    <link:label id="lab_us-gaap_FairValueByMeasurementFrequencyAxis_abd8f1bb-bd9a-4d71-b3c1-c1b3b737abbf_terseLabel_en-US" xlink:label="lab_us-gaap_FairValueByMeasurementFrequencyAxis" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Measurement Frequency [Axis]</link:label>
    <link:label id="lab_us-gaap_FairValueByMeasurementFrequencyAxis_label_en-US" xlink:label="lab_us-gaap_FairValueByMeasurementFrequencyAxis" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Measurement Frequency [Axis]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueByMeasurementFrequencyAxis" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_FairValueByMeasurementFrequencyAxis"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_FairValueByMeasurementFrequencyAxis" xlink:to="lab_us-gaap_FairValueByMeasurementFrequencyAxis" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_InterestBearingDepositLiabilities_a871f9d9-fdd1-4ec6-ba05-95cc833a7519_terseLabel_en-US" xlink:label="lab_us-gaap_InterestBearingDepositLiabilities" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Deposits - interest-bearing</link:label>
    <link:label id="lab_us-gaap_InterestBearingDepositLiabilities_b8f4c50d-b899-4a3f-9a28-e4b99b9472b0_totalLabel_en-US" xlink:label="lab_us-gaap_InterestBearingDepositLiabilities" xlink:role="http://www.xbrl.org/2003/role/totalLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Deposits - interest bearing</link:label>
    <link:label id="lab_us-gaap_InterestBearingDepositLiabilities_label_en-US" xlink:label="lab_us-gaap_InterestBearingDepositLiabilities" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Interest-Bearing Deposit Liabilities</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestBearingDepositLiabilities" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_InterestBearingDepositLiabilities"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_InterestBearingDepositLiabilities" xlink:to="lab_us-gaap_InterestBearingDepositLiabilities" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_InterestBearingDomesticDepositTimeDeposits_2ec2ae4f-f285-480b-ab4c-30637d9726f1_terseLabel_en-US" xlink:label="lab_us-gaap_InterestBearingDomesticDepositTimeDeposits" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Certificates of deposit</link:label>
    <link:label id="lab_us-gaap_InterestBearingDomesticDepositTimeDeposits_label_en-US" xlink:label="lab_us-gaap_InterestBearingDomesticDepositTimeDeposits" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Interest-Bearing Domestic Deposit, Time Deposits</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestBearingDomesticDepositTimeDeposits" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_InterestBearingDomesticDepositTimeDeposits"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_InterestBearingDomesticDepositTimeDeposits" xlink:to="lab_us-gaap_InterestBearingDomesticDepositTimeDeposits" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_TierOneLeverageCapitalToAverageAssets_f2a5a153-5332-47c2-b731-8ffbf36df742_terseLabel_en-US" xlink:label="lab_us-gaap_TierOneLeverageCapitalToAverageAssets" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Tier 1 Capital (to Average Assets)</link:label>
    <link:label id="lab_us-gaap_TierOneLeverageCapitalToAverageAssets_label_en-US" xlink:label="lab_us-gaap_TierOneLeverageCapitalToAverageAssets" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Banking Regulation, Tier 1 Leverage Capital Ratio, Actual</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_TierOneLeverageCapitalToAverageAssets" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_TierOneLeverageCapitalToAverageAssets"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_TierOneLeverageCapitalToAverageAssets" xlink:to="lab_us-gaap_TierOneLeverageCapitalToAverageAssets" xlink:type="arc" order="1"/>
    <link:label id="lab_slm_PercentOfPrivateLoansIndexedToLIBOROrSOFR_60921399-b780-4d74-b28f-d28ad917b48d_terseLabel_en-US" xlink:label="lab_slm_PercentOfPrivateLoansIndexedToLIBOROrSOFR" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Percent of private loans indexed to LIBOR</link:label>
    <link:label id="lab_slm_PercentOfPrivateLoansIndexedToLIBOROrSOFR_label_en-US" xlink:label="lab_slm_PercentOfPrivateLoansIndexedToLIBOROrSOFR" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Percent of Private Loans indexed to LIBOR Or SOFR</link:label>
    <link:label id="lab_slm_PercentOfPrivateLoansIndexedToLIBOROrSOFR_documentation_en-US" xlink:label="lab_slm_PercentOfPrivateLoansIndexedToLIBOROrSOFR" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Percent of Private Loans indexed to LIBOR Or SOFR</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_slm_PercentOfPrivateLoansIndexedToLIBOROrSOFR" xlink:href="slm-20230331.xsd#slm_PercentOfPrivateLoansIndexedToLIBOROrSOFR"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_slm_PercentOfPrivateLoansIndexedToLIBOROrSOFR" xlink:to="lab_slm_PercentOfPrivateLoansIndexedToLIBOROrSOFR" xlink:type="arc" order="1"/>
    <link:label id="lab_slm_FinancingReceivableAccruedInterestOriginationInterestOriginatedFiveOrMoreYearsBeforeLatestFiscalYear_8b0e4b96-98b7-4559-87a4-b1eb85e6ac2e_terseLabel_en-US" xlink:label="lab_slm_FinancingReceivableAccruedInterestOriginationInterestOriginatedFiveOrMoreYearsBeforeLatestFiscalYear" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Total accrued interest by origination vintage, After Year 5</link:label>
    <link:label id="lab_slm_FinancingReceivableAccruedInterestOriginationInterestOriginatedFiveOrMoreYearsBeforeLatestFiscalYear_label_en-US" xlink:label="lab_slm_FinancingReceivableAccruedInterestOriginationInterestOriginatedFiveOrMoreYearsBeforeLatestFiscalYear" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Financing Receivable, Accrued Interest, Origination Interest, Originated Five or More Years before Latest Fiscal Year</link:label>
    <link:label id="lab_slm_FinancingReceivableAccruedInterestOriginationInterestOriginatedFiveOrMoreYearsBeforeLatestFiscalYear_documentation_en-US" xlink:label="lab_slm_FinancingReceivableAccruedInterestOriginationInterestOriginatedFiveOrMoreYearsBeforeLatestFiscalYear" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Financing Receivable, Accrued Interest, Origination Interest, Originated Five or More Years before Latest Fiscal Year</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_slm_FinancingReceivableAccruedInterestOriginationInterestOriginatedFiveOrMoreYearsBeforeLatestFiscalYear" xlink:href="slm-20230331.xsd#slm_FinancingReceivableAccruedInterestOriginationInterestOriginatedFiveOrMoreYearsBeforeLatestFiscalYear"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_slm_FinancingReceivableAccruedInterestOriginationInterestOriginatedFiveOrMoreYearsBeforeLatestFiscalYear" xlink:to="lab_slm_FinancingReceivableAccruedInterestOriginationInterestOriginatedFiveOrMoreYearsBeforeLatestFiscalYear" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_TypeOfAdoptionMember_e6cb74f6-1b49-410a-be07-6a633e904f32_terseLabel_en-US" xlink:label="lab_us-gaap_TypeOfAdoptionMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Type of Adoption [Domain]</link:label>
    <link:label id="lab_us-gaap_TypeOfAdoptionMember_label_en-US" xlink:label="lab_us-gaap_TypeOfAdoptionMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Accounting Standards Update [Domain]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_TypeOfAdoptionMember" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_TypeOfAdoptionMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_TypeOfAdoptionMember" xlink:to="lab_us-gaap_TypeOfAdoptionMember" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_LongtermDebtTypeDomain_1b1ec6ab-de31-467e-a9a6-9d8d4b22b89c_terseLabel_en-US" xlink:label="lab_us-gaap_LongtermDebtTypeDomain" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Long-term Debt, Type [Domain]</link:label>
    <link:label id="lab_us-gaap_LongtermDebtTypeDomain_label_en-US" xlink:label="lab_us-gaap_LongtermDebtTypeDomain" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Long-Term Debt, Type [Domain]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongtermDebtTypeDomain" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_LongtermDebtTypeDomain"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_LongtermDebtTypeDomain" xlink:to="lab_us-gaap_LongtermDebtTypeDomain" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_OtherDebtSecuritiesMember_6516ae13-b452-4cf9-ace1-26c4d9abe128_terseLabel_en-US" xlink:label="lab_us-gaap_OtherDebtSecuritiesMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Other securities</link:label>
    <link:label id="lab_us-gaap_OtherDebtSecuritiesMember_label_en-US" xlink:label="lab_us-gaap_OtherDebtSecuritiesMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Other Debt Obligations [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherDebtSecuritiesMember" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_OtherDebtSecuritiesMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_OtherDebtSecuritiesMember" xlink:to="lab_us-gaap_OtherDebtSecuritiesMember" xlink:type="arc" order="1"/>
    <link:label id="lab_slm_FinancingReceivableAllowanceForCreditLossOriginatedThreeYearsBeforeCurrentFiscalYear_902a958f-6a62-409d-acc6-8629458efea3_negatedTerseLabel_en-US" xlink:label="lab_slm_FinancingReceivableAllowanceForCreditLossOriginatedThreeYearsBeforeCurrentFiscalYear" xlink:role="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Private Education Loans allowance for losses, Year 4</link:label>
    <link:label id="lab_slm_FinancingReceivableAllowanceForCreditLossOriginatedThreeYearsBeforeCurrentFiscalYear_label_en-US" xlink:label="lab_slm_FinancingReceivableAllowanceForCreditLossOriginatedThreeYearsBeforeCurrentFiscalYear" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Financing Receivable, Allowance For Credit Loss, Originated Three Years Before Current Fiscal Year</link:label>
    <link:label id="lab_slm_FinancingReceivableAllowanceForCreditLossOriginatedThreeYearsBeforeCurrentFiscalYear_documentation_en-US" xlink:label="lab_slm_FinancingReceivableAllowanceForCreditLossOriginatedThreeYearsBeforeCurrentFiscalYear" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Financing Receivable, Allowance For Credit Loss, Originated Three Years Before Current Fiscal Year</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_slm_FinancingReceivableAllowanceForCreditLossOriginatedThreeYearsBeforeCurrentFiscalYear" xlink:href="slm-20230331.xsd#slm_FinancingReceivableAllowanceForCreditLossOriginatedThreeYearsBeforeCurrentFiscalYear"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_slm_FinancingReceivableAllowanceForCreditLossOriginatedThreeYearsBeforeCurrentFiscalYear" xlink:to="lab_slm_FinancingReceivableAllowanceForCreditLossOriginatedThreeYearsBeforeCurrentFiscalYear" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_StatementOfStockholdersEquityAbstract_2ffda187-a1d1-4e3e-beb3-200c8c8b255f_terseLabel_en-US" xlink:label="lab_us-gaap_StatementOfStockholdersEquityAbstract" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Statement of Stockholders' Equity [Abstract]</link:label>
    <link:label id="lab_us-gaap_StatementOfStockholdersEquityAbstract_label_en-US" xlink:label="lab_us-gaap_StatementOfStockholdersEquityAbstract" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Statement of Stockholders' Equity [Abstract]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementOfStockholdersEquityAbstract" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_StatementOfStockholdersEquityAbstract"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_StatementOfStockholdersEquityAbstract" xlink:to="lab_us-gaap_StatementOfStockholdersEquityAbstract" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_FinancingReceivableTransferToHeldForSaleAllowanceForCreditLossExpenseReversal_5a6ddf84-17b0-44de-9a82-b310ec15cb55_terseLabel_en-US" xlink:label="lab_us-gaap_FinancingReceivableTransferToHeldForSaleAllowanceForCreditLossExpenseReversal" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Financing receivable allowance for credit loss, transfer to held-to-sale</link:label>
    <link:label id="lab_us-gaap_FinancingReceivableTransferToHeldForSaleAllowanceForCreditLossExpenseReversal_label_en-US" xlink:label="lab_us-gaap_FinancingReceivableTransferToHeldForSaleAllowanceForCreditLossExpenseReversal" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Financing Receivable, Transfer to Held-for-Sale, Allowance for Credit Loss, Expense Reversal</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinancingReceivableTransferToHeldForSaleAllowanceForCreditLossExpenseReversal" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_FinancingReceivableTransferToHeldForSaleAllowanceForCreditLossExpenseReversal"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_FinancingReceivableTransferToHeldForSaleAllowanceForCreditLossExpenseReversal" xlink:to="lab_us-gaap_FinancingReceivableTransferToHeldForSaleAllowanceForCreditLossExpenseReversal" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_e3d9b89d-cbb5-427b-928c-11b23348ed0c_terseLabel_en-US" xlink:label="lab_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Financing activities</link:label>
    <link:label id="lab_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_label_en-US" xlink:label="lab_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Net Cash Provided by (Used in) Financing Activities [Abstract]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract" xlink:to="lab_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract" xlink:type="arc" order="1"/>
    <link:label id="lab_slm_FinancingPercentageOfFFELPLoansInsuredAndGuaranteed_04e29ecd-fad2-4fe1-9b39-5afd74264a1d_terseLabel_en-US" xlink:label="lab_slm_FinancingPercentageOfFFELPLoansInsuredAndGuaranteed" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Percentage of FFELP loans insured and guaranteed (at least)</link:label>
    <link:label id="lab_slm_FinancingPercentageOfFFELPLoansInsuredAndGuaranteed_label_en-US" xlink:label="lab_slm_FinancingPercentageOfFFELPLoansInsuredAndGuaranteed" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Financing, Percentage of FFELP Loans Insured and Guaranteed</link:label>
    <link:label id="lab_slm_FinancingPercentageOfFFELPLoansInsuredAndGuaranteed_documentation_en-US" xlink:label="lab_slm_FinancingPercentageOfFFELPLoansInsuredAndGuaranteed" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Financing, Percentage of FFELP Loans Insured and Guaranteed</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_slm_FinancingPercentageOfFFELPLoansInsuredAndGuaranteed" xlink:href="slm-20230331.xsd#slm_FinancingPercentageOfFFELPLoansInsuredAndGuaranteed"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_slm_FinancingPercentageOfFFELPLoansInsuredAndGuaranteed" xlink:to="lab_slm_FinancingPercentageOfFFELPLoansInsuredAndGuaranteed" xlink:type="arc" order="1"/>
    <link:label id="lab_slm_USGovernmentSponsoredEnterprisesAndTreasuriesMember_de62c854-4745-47f0-a77c-3bd8f4b23ad7_terseLabel_en-US" xlink:label="lab_slm_USGovernmentSponsoredEnterprisesAndTreasuriesMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">U.S. government-sponsored enterprises and Treasuries</link:label>
    <link:label id="lab_slm_USGovernmentSponsoredEnterprisesAndTreasuriesMember_label_en-US" xlink:label="lab_slm_USGovernmentSponsoredEnterprisesAndTreasuriesMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">U.S. Government-Sponsored Enterprises and Treasuries [Member]</link:label>
    <link:label id="lab_slm_USGovernmentSponsoredEnterprisesAndTreasuriesMember_documentation_en-US" xlink:label="lab_slm_USGovernmentSponsoredEnterprisesAndTreasuriesMember" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">U.S. Government-Sponsored Enterprises and Treasuries</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_slm_USGovernmentSponsoredEnterprisesAndTreasuriesMember" xlink:href="slm-20230331.xsd#slm_USGovernmentSponsoredEnterprisesAndTreasuriesMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_slm_USGovernmentSponsoredEnterprisesAndTreasuriesMember" xlink:to="lab_slm_USGovernmentSponsoredEnterprisesAndTreasuriesMember" xlink:type="arc" order="1"/>
    <link:label id="lab_slm_PrivateEducationLoansSecuritizedIn2023Member_5e8fb9a1-301e-414b-8a0a-e0986c89757f_terseLabel_en-US" xlink:label="lab_slm_PrivateEducationLoansSecuritizedIn2023Member" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Private Education Loans Securitized In 2023</link:label>
    <link:label id="lab_slm_PrivateEducationLoansSecuritizedIn2023Member_label_en-US" xlink:label="lab_slm_PrivateEducationLoansSecuritizedIn2023Member" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Private Education Loans Securitized In 2023 [Member]</link:label>
    <link:label id="lab_slm_PrivateEducationLoansSecuritizedIn2023Member_documentation_en-US" xlink:label="lab_slm_PrivateEducationLoansSecuritizedIn2023Member" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Private Education Loans Securitized In 2023</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_slm_PrivateEducationLoansSecuritizedIn2023Member" xlink:href="slm-20230331.xsd#slm_PrivateEducationLoansSecuritizedIn2023Member"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_slm_PrivateEducationLoansSecuritizedIn2023Member" xlink:to="lab_slm_PrivateEducationLoansSecuritizedIn2023Member" xlink:type="arc" order="1"/>
    <link:label id="lab_slm_FinancingReceivableAllowanceForCreditLossExcludingAccruedInterestWriteoffOriginatedFiveOrMoreYearsBeforeLatestFiscalYear_99a1c2c3-f555-4bd5-a732-a0d8eaf4d66e_negatedTerseLabel_en-US" xlink:label="lab_slm_FinancingReceivableAllowanceForCreditLossExcludingAccruedInterestWriteoffOriginatedFiveOrMoreYearsBeforeLatestFiscalYear" xlink:role="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Current period gross charge-offs, After Year 5</link:label>
    <link:label id="lab_slm_FinancingReceivableAllowanceForCreditLossExcludingAccruedInterestWriteoffOriginatedFiveOrMoreYearsBeforeLatestFiscalYear_label_en-US" xlink:label="lab_slm_FinancingReceivableAllowanceForCreditLossExcludingAccruedInterestWriteoffOriginatedFiveOrMoreYearsBeforeLatestFiscalYear" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Financing Receivable, Allowance for Credit Loss, Excluding Accrued Interest, Writeoff, Originated Five Or More Years Before Latest Fiscal Year</link:label>
    <link:label id="lab_slm_FinancingReceivableAllowanceForCreditLossExcludingAccruedInterestWriteoffOriginatedFiveOrMoreYearsBeforeLatestFiscalYear_documentation_en-US" xlink:label="lab_slm_FinancingReceivableAllowanceForCreditLossExcludingAccruedInterestWriteoffOriginatedFiveOrMoreYearsBeforeLatestFiscalYear" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Financing Receivable, Allowance for Credit Loss, Excluding Accrued Interest, Writeoff, Originated Five Or More Years Before Latest Fiscal Year</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_slm_FinancingReceivableAllowanceForCreditLossExcludingAccruedInterestWriteoffOriginatedFiveOrMoreYearsBeforeLatestFiscalYear" xlink:href="slm-20230331.xsd#slm_FinancingReceivableAllowanceForCreditLossExcludingAccruedInterestWriteoffOriginatedFiveOrMoreYearsBeforeLatestFiscalYear"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_slm_FinancingReceivableAllowanceForCreditLossExcludingAccruedInterestWriteoffOriginatedFiveOrMoreYearsBeforeLatestFiscalYear" xlink:to="lab_slm_FinancingReceivableAllowanceForCreditLossExcludingAccruedInterestWriteoffOriginatedFiveOrMoreYearsBeforeLatestFiscalYear" xlink:type="arc" order="1"/>
    <link:label id="lab_slm_ABCPBorrowingsMember_efca9195-9b17-4f87-bda0-b400c0003ba9_verboseLabel_en-US" xlink:label="lab_slm_ABCPBorrowingsMember" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Secured Borrowing Facility</link:label>
    <link:label id="lab_slm_ABCPBorrowingsMember_6c3ce156-9212-47ef-9248-a1dc1d515534_terseLabel_en-US" xlink:label="lab_slm_ABCPBorrowingsMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">ABCP borrowings</link:label>
    <link:label id="lab_slm_ABCPBorrowingsMember_label_en-US" xlink:label="lab_slm_ABCPBorrowingsMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">ABCP Borrowings [Member]</link:label>
    <link:label id="lab_slm_ABCPBorrowingsMember_documentation_en-US" xlink:label="lab_slm_ABCPBorrowingsMember" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">ABCP Borrowings [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_slm_ABCPBorrowingsMember" xlink:href="slm-20230331.xsd#slm_ABCPBorrowingsMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_slm_ABCPBorrowingsMember" xlink:to="lab_slm_ABCPBorrowingsMember" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_OtherNoninterestExpense_b02ecf70-d976-436b-802f-e8c56132d4ae_terseLabel_en-US" xlink:label="lab_us-gaap_OtherNoninterestExpense" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Other operating expenses</link:label>
    <link:label id="lab_us-gaap_OtherNoninterestExpense_label_en-US" xlink:label="lab_us-gaap_OtherNoninterestExpense" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Other Noninterest Expense</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherNoninterestExpense" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_OtherNoninterestExpense"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_OtherNoninterestExpense" xlink:to="lab_us-gaap_OtherNoninterestExpense" xlink:type="arc" order="1"/>
    <link:label id="lab_slm_NetUnamortizedPremiumOrDiscountOriginatedTwoYearsBeforeCurrentFiscalYear_5cf10008-29b0-4409-863f-57ae808be931_terseLabel_en-US" xlink:label="lab_slm_NetUnamortizedPremiumOrDiscountOriginatedTwoYearsBeforeCurrentFiscalYear" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Private Education Loans deferred origination costs and unamortized premium/(discount), Year 3</link:label>
    <link:label id="lab_slm_NetUnamortizedPremiumOrDiscountOriginatedTwoYearsBeforeCurrentFiscalYear_label_en-US" xlink:label="lab_slm_NetUnamortizedPremiumOrDiscountOriginatedTwoYearsBeforeCurrentFiscalYear" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Net Unamortized Premium Or Discount, Originated Two Years Before Current Fiscal Year</link:label>
    <link:label id="lab_slm_NetUnamortizedPremiumOrDiscountOriginatedTwoYearsBeforeCurrentFiscalYear_documentation_en-US" xlink:label="lab_slm_NetUnamortizedPremiumOrDiscountOriginatedTwoYearsBeforeCurrentFiscalYear" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Net Unamortized Premium Or Discount, Originated Two Years Before Current Fiscal Year</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_slm_NetUnamortizedPremiumOrDiscountOriginatedTwoYearsBeforeCurrentFiscalYear" xlink:href="slm-20230331.xsd#slm_NetUnamortizedPremiumOrDiscountOriginatedTwoYearsBeforeCurrentFiscalYear"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_slm_NetUnamortizedPremiumOrDiscountOriginatedTwoYearsBeforeCurrentFiscalYear" xlink:to="lab_slm_NetUnamortizedPremiumOrDiscountOriginatedTwoYearsBeforeCurrentFiscalYear" xlink:type="arc" order="1"/>
    <link:label id="lab_slm_Cashpaidforbrokereddepositplacementfee_144ad631-81a0-4776-baf4-148819bbe75b_negatedLabel_en-US" xlink:label="lab_slm_Cashpaidforbrokereddepositplacementfee" xlink:role="http://www.xbrl.org/2009/role/negatedLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Brokered deposit placement fee</link:label>
    <link:label id="lab_slm_Cashpaidforbrokereddepositplacementfee_label_en-US" xlink:label="lab_slm_Cashpaidforbrokereddepositplacementfee" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Cash paid for brokered deposit placement fee</link:label>
    <link:label id="lab_slm_Cashpaidforbrokereddepositplacementfee_documentation_en-US" xlink:label="lab_slm_Cashpaidforbrokereddepositplacementfee" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Cash paid for brokered deposit placement fee</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_slm_Cashpaidforbrokereddepositplacementfee" xlink:href="slm-20230331.xsd#slm_Cashpaidforbrokereddepositplacementfee"/>
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